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Aaptol (Cetirizine)

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Aaptol is an antihistamine. When you're exposed to an allergen, such as pollen or dust, your body releases histamine to help get rid of it. Histamine is a chemical in the body that can cause allergy symptoms. Aaptol works by blocking histamine, which can help prevent or relieve itchiness and other allergy symptoms.

Other names for this medication:
Alleroff, Allicet, Alrin, Amven, Cepar, Cetirizine, Cetoday, Cetriken, Cetrina, Cetrine, Cetrisan, Cetrish, Cetrisyn, Cetrix, Cetrizine, Cetroffin, Cezor, Cinzim, Cistin, Citrazan, Coldec, Coriz, Fedrine, Flamoset, Flomicet, Fulday, Grecet, Hicet, Hydrozet, Illah, Incez, Incold, Kidcet, Mastifen, Morazin, Noalzy, Olcit, Racezine, Rizkold, Setrik, Solodryl, Sparzin, Spazin, Triact, Winnow, Zicet, Zimat

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Prometrium, Inderal, Luvox, Acticin, Zyrtec, Levaquin, Omnicef, Amaryl

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Also known as: Cetirizine


Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.

Cough/cold combination products contain more than one ingredient. For example, some products may contain an antihistamine, a decongestant, and an analgesic, in addition to a medicine for coughing. If you are treating yourself, it is important to select a product that is best for your symptoms. Also, in general, it is best to buy a product that includes only those medicines you really need. If you have questions about which product to buy, check with your pharmacist.

Since different products contain ingredients that will have different precautions and side effects, it is important that you know the ingredients of the medicine you are taking. The different kinds of ingredients that may be found in cough/cold combinations include:

Antihistamines—Antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They also help relieve some symptoms of the common cold, such as sneezing and runny nose. They work by preventing the effects of a substance called histamine, which is produced by the body. Some examples of antihistamines contained in these combinations are:

Bromodiphenhydramine Brompheniramine Carbinoxamine Chlorpheniramine Dexchlorpheniramine Diphenhydramine Doxylamine Phenindamine Pheniramine Phenyltoloxamine Pyrilamine Promethazine Triprolidine

Decongestants—Decongestants produce a narrowing of blood vessels. This leads to clearing of nasal congestion. However, this effect may also increase blood pressure in patients who have high blood pressure. These include:

Ephedrine Phenylephrine Pseudoephedrine

Antitussives—Antitussives help relieve coughing and are some contain a narcotic. These antitussives act directly on the cough center in the brain. Narcotics may become habit-forming, causing mental or physical dependence, if used for a long time. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.

Narcotic antitussives Codeine Dihydrocodeine Hydrocodone Hydromorphone

Non-narcotic antitussives Carbetapentane Caramiphen Dextromethorphan

Expectorants—Expectorants work by loosening the mucus or phlegm in the lungs. The main expectorant used in cough and cold medicines is guaifenesin. Other ingredients added as expectorants (for example, ammonium chloride, calcium iodide, iodinated glycerol, ipecac, potassium guaiacolsulfonate, potassium iodide, and sodium citrate) have not been proven to be effective. In general, the best thing you can do to loosen mucus or phlegm is to drink plenty of water.

Analgesics—Analgesics are used in these combination medicines to help relieve the aches and pain that may occur with the common cold. These include:

Acetaminophen Aspirin Other salicylates such as salicylamide and sodium salicylate

The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large amounts of both medicines are taken together for a long time. However, taking the recommended amounts of combination medicines that contain both acetaminophen and a salicylate for short periods of time has not been shown to cause these unwanted effects.

Anticholinergics—Anticholinergics, such as homatropine may help produce a drying effect in the nose and chest.

These cough and cold combinations are available both over-the-counter (OTC) and with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .


This section provides information on the proper use of a number of products that contain cough and cold combinations. It may not be specific to Aaptol-D. Please read with care.

To help loosen mucus or phlegm in the lungs, drink a glass of water after each dose of this medicine, unless otherwise directed by your doctor.

Take this medicine only as directed. Do not take more of it and do not take it more often than recommended on the label, unless otherwise directed by your doctor. To do so may increase the chance of side effects.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

For patients taking the extended-release capsule or tablet form of this medicine:

Swallow the capsule or tablet whole. Do not crush, break, or chew before swallowing. If the capsule is too large to swallow, you may mix the contents of the capsule with applesauce, jelly, honey, or syrup and swallow without chewing.

For patients taking the extended-release oral solution or oral suspension form of this medicine:

Do not dilute with fluids or mix with other drugs.

For patients taking a combination medicine containing an antihistamine and/or aspirin or other salicylate:

Take with food or a glass of water or milk to lessen stomach irritation, if necessary.

If a combination medicine containing aspirin has a strong vinegar-like odor, do not use it. This odor means the medicine is breaking down. If you have any questions about this, check with your pharmacist.


If you overdose Aaptol and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Aaptol overdosage: extreme sleepiness, confused mental state, weakness.


Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Keep the liquid form of this medicine from freezing. Do not refrigerate the syrup.

Side effects

The most common side effects associated with Aaptol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Very young children are usually more sensitive to the effects of this medicine. Before giving any of these combination medicines to a child, check the package label very carefully. Some of these medicines are too strong for use in children. If you are not certain whether a specific product can be given to a child, or if you have any questions about the amount to give, check with your health care professional, especially if it contains:

Antihistamines—Nightmares, unusual excitement, nervousness, restlessness, or irritability may be more likely to occur in children taking antihistamines. Decongestants (e.g., ephedrine, phenylephrine, pseudoephedrine—Increases in blood pressure may be more likely to occur in children taking decongestants. Iodides (e.g., calcium iodide and iodinated glycerol)—These medicines pass into the breast milk and may cause unwanted effects, such as underactive thyroid, in the baby. Narcotic antitussives (e.g., codeine, dihydrocodeine, hydrocodone, and hydromorphone)—Breathing problems may be especially likely to occur in children younger than 2 years of age taking narcotic antitussives. Also, unusual excitement or restlessness may be more likely to occur in children receiving these medicines. Salicylates (e.g., aspirin)—Do not give medicines containing aspirin or other salicylates to a child or teenager with a fever or other symptoms of a virus infection, especially flu or chickenpox, without first discussing its use with your child's doctor. This is very important because salicylates may cause a serious illness called Reye's syndrome in children with fever caused by a virus infection, especially flu or chickenpox. Also, children may be more sensitive to the aspirin or other salicylates contained in some of these medicines, especially if they have a fever or have lost large amounts of body fluid because of vomiting, diarrhea, or sweating.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

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Shrinkage of uterine fibroids during therapy with goserelin (Zoladex): a luteinizing hormone-releasing hormone agonist administered as a monthly subcutaneous depot. A mechanical theory to account for bitemporal hemianopia from chiasmal compression. Accumulative effect of two low doses of irradiation in inducing an adaptive response in human lymphocytes. The most striking differences between the rabbit and insect S1 are values for the Vmax and the Km of actin during actin-activation of the MgATPase activity, which are up to an order of magnitude lower and greater in the insect than in the rabbit, respectively. In contrast, no GnRH appositions were tenormin atenolol dosage observed in adult females at diestrus. Caregiving Immediately After Stroke: A Study of Uncertainty in Caregivers of Older Adults.

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We conclude that cessation of cell replication and the onset of crystallin production are not directly linked. Increased levels of Ang-2 have been shown to be correlated with abnormal tumor angiogenesis in several malignancies. Novel eradication strategies should target HIV persistence in CCR6CD4 T cells from various anatomic sites. Based on BRT analysis patients undergoing TKA may be allowed to return to driving 6 weeks after surgery. Use of oligonucleotide microarrays for rapid detection and serotyping of acute respiratory disease-associated adenoviruses. Several experimental techniques, such as X-Ray crystallography, nuclear magnetic resonance and electron microscopy are available to gain insight about the structure and function of a protein molecule. Recombinantly produced human receptor in yeast extracts was attached to scintillating microtitration plates. To establish a simple assay to simultaneously monitor the expression of skin-related homing molecules and their proliferative response to an allergen on peripheral T cells. Ancient protein sequences are increasingly used to elucidate the phylogenetic relationships between extinct and extant mammalian taxa. It has been demonstrated that the mRNA-expression of BDNF is increased after TH-treatment during the first postnatal weeks.

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Hospital transmitted Candida auris infections confirmed in the US. It is suggested that major mechanism of atenolol tenormin cost action of fluoxetine is that of elevating brain tryptophan concentration and hence 5-HT synthesis by increasing the availability of circulating tryptophan to the brain secondarily to inhibition of major tryptophan degrading enzyme, hepatic tryptophan pyrrolase. Prolonged per-laryngeal endotracheal intubation in children: 40 years on--reply. The rinse water of carpet shell and giant tiger prawn showed higher attractiveness for ovipostion than the other candidate attractants. However, enrichment devices vary as to their effectiveness in normalizing the behavioral repertoire and eliminating abnormal behavior. Anterior segment optical coherence tomography in subtypes of angle closure glaucoma. Molecular genetics of human color vision: the genes encoding blue, green, and red pigments. To account for time-dependent batch effects in IC 50 measurements, we employ independent test sets generated with more recent GDSC data than that used to train the predictors and show that this is a more realistic validation than K-fold cross-validation. The synthesis and biological properties of seven polyoxins (4-10) designed to avoid peptidase hydrolysis in Candida albicans are presented. The investigation of antimicrobial screening data revealed that all the tested compounds showed moderate to good microbial inhibitions.

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Do all patients in the phase I oncology trials need to be hospitalized?. Two artificial 55-meter experimental streams were dosed with different concentrations of Fire-Trol GTS-R, or uncontaminated for a control. Characterization of monoclonal antibodies against prostate specific antigen produced by genetic immunization. Together, our results suggest that the evolutionary origin of Cys-49 within the plants has provided R2R3 MYB domains with a regulatory feature not present in animal MYB domains, highlighting fundamental structural and functional differences between similar DNA-binding domains from plants and animals. Impact of stress response in development of first-episode psychosis in schizophrenia: An overview of systematic reviews. We report the simultaneous use of cardiac re-synchronisation therapy and total cavopulmonary connection in a patient with dyssynchrony, wide QRS, and cardiac failure. Brassica juncea HMG-CoA synthase: localization of mRNA and protein. Catheter reperfusion to allow optimal coronary bypass grafting following failed transluminal coronary angioplasty. We used a structured means Social Relations Model in order to examine negativity in multiple levels of the family system.

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Upon sensing of the required cell mass, the proliferation response is terminated (termination phase) and is mainly mediated by transforming growth factor-beta and activins. The increased effectiveness has to be taken into account in treatment planning in order to estimate the corresponding photon equivalent doses in normal and tumor tissues, thus allowing a link e.g., to normal tissue dose limits in conventional photon therapy. To better understand it, we analyzed the QTc interval duration in patients with heart failure with high B-type natriuretic peptide (BNP) levels and analyzed the combined prognostic impact of prolonged QTc and elevated BNP. A case of the Carney triad is presented, and the related literature is discussed. Hypoxic incubation leads to concerted changes of carbonic anhydrase activity and 2.3 DPG concentration of chick embryo red cells.

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We analyse the therapeutic options regarding the use of stimulants when both disorders coexist and we endorse the association of antiepileptic and psychostimulant drugs when necessary. Owing to the importance of angiogenesis, a relatively simple and rapid in vivo method to determine the angiogenic potential of compounds is desirable to valium 5mg pill augment in vitro findings. We cloned the MDR-1 and MRP-1 gene promoters containing Runx binding sites and constructed the luciferase reporter vectors of these 2 promoters. Using in vitro RNA synthesis assays, we show that a depurinated template causes the BMV replicase to stall at the template nucleotide adjacent to the missing base. The recombinant plasmids TR421-preS2/S and TR421-preS2/S-C3d3 were transfected into the human breast cancer cells of the line 4T1 as a transient expression system. The construct containing the structural gene of the type II DNA topoisomerase of Drosophila melanogaster fused to the sequence of the chloroplast transit peptide directed by the 35 S promoter was produced on the basis of the binary vector Bin 19. As a consequence the actually relevant results might be overlooked, because of the large number of spurious results accumulating in the literature. When Lipofectamine (a liposome-type gene carrier) was used as a complex forming reagent with DNA, the cytosolic fraction caused no DNA release from the complex. The purpose of this prospective study was to determine the value of detection of H-ras (also known as HRAS) mutations in urine sediment DNA as a clinical indicator of tumor presence, recurrence, and/or progression. HaCaT keratinocytes were characterized by a constitutive phosphorylation of janus kinase (JAK)-2.

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