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Acivir (Acyclovir)
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Acivir

Acivir is an antiviral medication used for the treatment of herpes, shingles, and chickenpox. It comes in many different formulations including a capsule, oral and buccal tablet, and topical cream or ointment.

Other names for this medication:
Acivir, Acloriv, Aclovir, Acvirax, Acycloguanosine, Acyclor, Acyclovir, Acylab, Axovir, Civir, Clovir, Clovirax, Clyvir, Herpex, Herpovir, Lyrovir, Nisivir, Ocuvir, Ophtrhovir, Oveer, Psyvir, Rivol, Rovir, Rowapil, Virex, Viroderm, Vivorax, Zovir, Zoylex

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Also known as: Acyclovir

Description

{name} Topical (for the skin) is an antiviral medicine that is used to treat skin symptoms caused by the herpes virus.

{name} Topical cream is used to treat cold sores on the lips and face.

{name} Topical ointment is used to treat genital herpes lesions.

There is no cure for herpes and acyclovir will not prevent you from developing symptoms in the future.

Dosage

Patient information about the treatment of herpes, chickenpox, or shingles is available with this medicine. Read it carefully before using this medicine.

Acyclovir is best used as soon as possible after the symptoms of herpes infection or shingles (for example, pain, burning, blisters) begin to appear.

If you are taking acyclovir for the treatment of chickenpox, it is best to start taking acyclovir as soon as possible after the first sign of the chickenpox rash, usually within one day.

Acyclovir capsules, tablets, and oral suspension may be taken with meals or on an empty stomach.

Acyclovir is best taken with a full glass (8 ounces) of water.

If you are using acyclovir oral suspension, use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your herpes infection, chickenpox, or shingles, keep taking acyclovir for the full time of treatment, even if your symptoms begin to clear up after a few days. Do not miss any doses. However, do not use this medicine more often or for a longer time than your doctor ordered.

If you are taking acyclovir capsules, tablets, or oral suspension, you should drink plenty of water to avoid becoming dehydrated.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules, oral suspension, or tablets): For treatment of genital herpes: Adults and children 12 years of age and older—200 milligrams (mg) five times a day for ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. For prevention of recurrent outbreaks of genital herpes infections: Adults and children 12 years of age and older—200 to 400 mg two to five times a day for five days or up to twelve months, depending on how often your outbreaks of infection occur. Children up to 12 years of age—Use and dose must be determined by the doctor. For treatment of chickenpox: Adults and children who weigh over 88 pounds (40 kilograms)—800 mg four times a day for five days. Children 2 years of age and older and weighing 88 pounds (40 kilograms) or less—Dose is based on body weight and must be determined by the doctor. The usual dose is 20 mg per kilogram (kg) of body weight, up to 800 mg, four times a day for five days. Children up to 2 years of age—Use and dose must be determined by the doctor. For treatment of shingles: Adults and children 12 years of age and older—800 mg five times a day for seven to ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. For injection dosage form: For treatment of herpes of the brain, genitals, or mucous membranes, or for the treatment of shingles: Adults and children 12 years of age and older—Dose is based on body weight and must be determined by the doctor. The usual dose is 5 to 10 mg of acyclovir per kg (2.3 to 4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period, and repeated every eight hours for five to ten days. Children up to 12 years of age—Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg to 20 mg of acyclovir per kg (4.5 mg to 9.1 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for seven to ten days. For treatment of widespread herpes virus infection in newborns: Infants from birth to 3 months of age—Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg of acyclovir per kg (4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for ten days.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Acivir dosage information

Side effects

The most common side effects associated with Acivir are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Qualitative narratives described three pathways to care: elder care only, limited life course of care, and live course of care. Levels of evidence were judged as outlined by the Canadian Task Force on the Periodic Health Examination. Here we confirm that CED-9 and CED-4 interact and using a series of deletion mutants, demonstrate that only short N-terminal deletions are tolerated in each molecule without loss-of-interaction. Animals were killed 4 h after the final EB/5 alpha-DHT injection and their brains processed for in vitro autoradiography. Neurological deficits were significantly decreased in rats treated with lithium at 24 and 48 hours after ischemia. We conclude that the bulk of the steroidogenic pool of cholesterol, mobilized by Bt2cAMP for acute steroidogenesis, originates from the plasma membrane. Treadmill exercise stress testing for identifying patients with a higher likelihood of coronary artery disease (CAD) before elective coronary angiography is recommended in the current guidelines.

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Using validated scales, 178 patients from the general population diagnosed with newly developed seizures were assessed, at a point in time when the nature of their seizures was yet unknown to either doctors or patients. The cytotoxicity effects of all compounds from the MGC-803, HepG2, T24, NCI-H460, Spca-2, and HL-7702 cell lines were studied by MTT assays. Our findings suggest that maternal mRNA stored during oogenesis is utilized during the preimplantation period. The capabilities of FIP-gts and chloroquine to induce cytotoxicity and sub-G1 phase accumulation were abolished in autophagy-defective cells. We suggest that the unusual inheritance pattern of RD is due to these alleles, either by changing the pattern of expression of Cox-2 or making Cox-2 levels susceptible to influences of other genes or environmental factors that play an unknown but important role in the development of RD in dogs. The most common clinical feature of malaria is fever, which may present months and occasionally years after exposure which can lead to failure or delay in the diagnosis. Oral Mucosa Harbors a High Frequency of Endothelial Cells: A Novel Postnatal Cell Source for Angiogenic Regeneration.

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In the present study, we demonstrate for the first time the uptake of lipophorin (Lp), the main lipid-transporting particle of insect hemolymph. purpurea and an experimental vegetation emerging from natural seed banks on a natural soil was studied during two successive growth seasons under natural radiation and temperature conditions.Growth and seed production were found to be strongly reduced and germination was inhibited in the early/midsuccessional vegetation. A strain with only enterochelin remained sensitive to the bactericidal action of streptonigrin, suggesting that assimilated iron was contributed to an intracellular pool from which the rate of its withdrawal for growth is probably concentration dependent. The New York Statewide Planning and Research Cooperative System was used to identify 33,582 patients undergoing revision THA between 2000 and 2013. New thioderivatives of gossypol and gossypolone, as prodrugs of cytotoxic agents. Testing Compounds for Antiviral Activity in Cell Cultures Infected with HIV. Thermography, a central component of a large preventive health care unit. Sepsis leads to an overwhelming inflammatory response of the host and is usually accompanied by well-known clinical symptoms (fever, tachycardia, leukocytosis, and so on) and the accompanying systemic inflammatory response syndrome (SIRS). Reform of undergraduate medical teaching in the United Kingdom: a triumph of evangelism over common sense.

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Although elevated levels of IL-6 may correlate with the extent of left ventricular dysfunction in IDC, the markedly elevated IL-6 levels did not correlate with left ventricular function in HC. However, little is known about the biodegradation potential or basic microbial ecology of ULO-contaminated soils. In the final two sections (7 and 8), we discuss the current status in understanding of electronic structures and properties of SAMs in electrochemical environments and what could be expected for future perspectives. In the last few years 5-HT receptors have been cloned in many animal species, and there is evidence that different 5-HT receptors are also present in ascidians. 15 cases of cholesteatoma coexisting with cholesterol granuloma were found among the 63 patients. External Validation of the Cancer of the Prostate Risk Assessment Postsurgical Score for Prediction of Disease Recurrence after Radical Prostatectomy. At the population level, most women found epidural analgesia effective for labor pain relief, but specific attention should be paid to obese parturients and multiparous women not receiving oxytocin. Implant Composed of Demineralized Bone and Mesenchymal Stem Cells Genetically Modified with AdBMP2/AdBMP7 for the Regeneration of Bone Fractures in Ovis aries. These were all with common-type atrial flutter, treated by RFCA for the posterior isthmus, without difficulty.

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Genetic evidence for tula virus in Microtus arvalis and Microtus agrestis populations in Croatia. Comparison between intra-operative fine needle aspiration cytology and rapid histopathologic examination of a pancreatic mass. After this period long-term results depend on progression of the disease in other coronary arteries or segments. The antistressor and antioxidant properties of preparations from the underground part of elfwort (Inula helenium) were studied on a model of acute stress in mice. Other possible evidence of this is focal interruption of the cyst wall and the presence of peritoneal fluid around the adnexa. After ligament plastic the bore canal for the alloplastic ligament is visible. Major advances in the field have notably been possible thanks to the development of computer simulations and live quantitative imaging protocols in recent years.

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Several steps of the maturation processes on the sperm plasma membrane are mediated by external enzymes and secretions derived from the epithelium lining of the genital tract. In six cases, four surgical and two necropsy, these fibrils contained immunoreactive alpha human atrial natriuretic peptide. Clinical skin involvement was evaluated using the modified Rodnan skin score. The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas. These results suggest, that recycling GB into agricultural soils has the potential to be developed into a system combining bioenergy generation from agricultural residues and crop production, while maintaining soil quality.

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This study assessed the effects of matching clients from a non-English-speaking background with bilingual, bicultural clinicians in a mental health system in Australia that emphasizes community-based psychiatric case management. This case illustrated the difficulty of early diagnosis of such infrequent complication and suggested that dysphagia following anterior cervical spine surgery should prompt cervical imaging. Age or vocabulary size did not predict the expansion of f0 or intensity in words, whereas vocabulary size was related to the production of more even-timed syllables. In 7 out of these 10 cases, the leukemic cells responded to both cytokines. Accordingly, stenting of the proximal LAD using SES might prove a suitable alternative to surgery. In this context, this paper presents experimental results on the application of a combined sequential ozonation-activated carbon-biological system to treat effluents containing chlorinated aromatic contaminants from chlorine based pulp bleaching. Enhanced full-face skin rejuvenation using synchronous intense pulsed optical and conducted bipolar radiofrequency energy (ELOS): introducing selective radiophotothermolysis.

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