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Acyclovir

Acyclovir is an inexpensive drug used to treat or prevent infections caused by certain kinds of viruses. Examples of these infections include herpes and shingles. This drug is slightly more popular than comparable drugs. It is available in generic and brand form.

Other names for this medication:
Accrivir, Aciherpin, Acirax, Acivir, Acloriv, Acvirall, Acvirax, Acyclor, Alovir, Axovir, Cevirin, Civir, Cloviderm, Clyvir, Cutivir, Cycloex, Docvir, Herperax, Herpex, Herzovir, Lyrovir, Okavir, Ophtrhovir, Optiviral, Oveer, Ridoherp, Rivol, Rowapil, Setuvir, Trikase, Virclo, Viroderm, Vivorax, Zovir, Zoylex

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Description

Acyclovir belongs to the family of medicines called antivirals, which are used to treat infections caused by viruses. Usually these medicines work for only one kind or group of virus infections.

Acyclovir is used to treat the symptoms of chickenpox, shingles, herpes virus infections of the genitals (sex organs), the skin, the brain, and mucous membranes (lips and mouth), and widespread herpes virus infections in newborns. Acyclovir is also used to prevent recurrent genital herpes infections. Although acyclovir will not cure herpes, it does help relieve the pain and discomfort and helps the sores (if any) heal faster.

Acyclovir may also be used for other virus infections as determined by your doctor. However, it does not work in treating certain virus infections, such as the common cold.

Acyclovir is available only with your doctor's prescription.

Dosage

Patient information about the treatment of herpes, chickenpox, or shingles is available with this medicine. Read it carefully before using this medicine.

Acyclovir is best used as soon as possible after the symptoms of herpes infection or shingles (for example, pain, burning, blisters) begin to appear.

If you are taking acyclovir for the treatment of chickenpox, it is best to start taking acyclovir as soon as possible after the first sign of the chickenpox rash, usually within one day.

Acyclovir capsules, tablets, and oral suspension may be taken with meals or on an empty stomach.

Acyclovir is best taken with a full glass (8 ounces) of water.

If you are using acyclovir oral suspension, use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your herpes infection, chickenpox, or shingles, keep taking acyclovir for the full time of treatment, even if your symptoms begin to clear up after a few days. Do not miss any doses. However, do not use this medicine more often or for a longer time than your doctor ordered.

If you are taking acyclovir capsules, tablets, or oral suspension, you should drink plenty of water to avoid becoming dehydrated.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules, oral suspension, or tablets): For treatment of genital herpes: Adults and children 12 years of age and older—200 milligrams (mg) five times a day for ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. For prevention of recurrent outbreaks of genital herpes infections: Adults and children 12 years of age and older—200 to 400 mg two to five times a day for five days or up to twelve months, depending on how often your outbreaks of infection occur. Children up to 12 years of age—Use and dose must be determined by the doctor. For treatment of chickenpox: Adults and children who weigh over 88 pounds (40 kilograms)—800 mg four times a day for five days. Children 2 years of age and older and weighing 88 pounds (40 kilograms) or less—Dose is based on body weight and must be determined by the doctor. The usual dose is 20 mg per kilogram (kg) of body weight, up to 800 mg, four times a day for five days. Children up to 2 years of age—Use and dose must be determined by the doctor. For treatment of shingles: Adults and children 12 years of age and older—800 mg five times a day for seven to ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. For injection dosage form: For treatment of herpes of the brain, genitals, or mucous membranes, or for the treatment of shingles: Adults and children 12 years of age and older—Dose is based on body weight and must be determined by the doctor. The usual dose is 5 to 10 mg of acyclovir per kg (2.3 to 4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period, and repeated every eight hours for five to ten days. Children up to 12 years of age—Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg to 20 mg of acyclovir per kg (4.5 mg to 9.1 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for seven to ten days. For treatment of widespread herpes virus infection in newborns: Infants from birth to 3 months of age—Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg of acyclovir per kg (4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for ten days.

Overdose

An overdose of Acyclovir Topical is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

Storage

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Acyclovir are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Douglas-fir (Pseudotsuga menziesii)-spruce budworm (Choristoneura occidentalis) interactions: the effect of nutrition, chemical defenses, tissue phenology, and tree physical parameters on budworm success. An adaptive control system (NEURADAPT) based on artificial neural networks (ANNs) was developed to control the knee joint in accordance with desired trajectories by stimulating quadriceps muscles. Using a lipase as a high-throughput screening method for measuring the enantiomeric excess of allylic acetates. Relationships between serum soluble leptin receptor level and serum leptin and adiponectin levels, insulin resistance index, lipid profile, and leptin receptor gene polymorphisms in the Japanese population. Comparative studies on the function of the metapleural gland in ants. Urinary 1-POH levels in the rats of the exposure group increased remarkably over those of the control group, 2.4 times as much by the 2nd week of exposure and 5.6 times by the 4th and 8th weeks. Our findings vindicate that stochastic resonance does occur in these nonlinear, globally coupled biological systems.

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The presence of a factor toxic to pancreatic beta cells in some collagenase preparations. When all inflammatory myopathy patients (polymyositis, dermatomyositis, and polymyositis plus second connective tissue disease) were compared with normal adults, their muscle biopsies had fewer capillaries per fiber over the same diameter range. Previous study (Mays, ) with a known-age collection of human remains suggested the potential of this phenomenon for age estimation in remains of adults who have lost one or more molar teeth. We further showed that exposure of T-ALL cells to MSCs decreased mitochondrial reactive oxygen species (ROS) levels and promoted a pro-glycolytic shift that was characterized by increased glucose uptake and lactate production with concomitant reductions in adenosine triphosphate production and mitochondrial membrane potential. Two methods were used: Method 1, which corresponded with results of the NFCS (over-sampled for low socio-economic status), and Method 2, which was based on ethnic proportions of the population. Induction of leptin resistance by activation of cAMP-Epac signaling. Oral health related quality of life depending amiloride dosing on oral health and specific factors in patients after lung transplantation.

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Nitroglycerin and NONOate produced similar vasodilation in non-alcohol-fed and alcohol-fed male and female rats. Results indicate that it may be possible to determine whether stimulation of different implant channels activates different regions of cochleotopically organized auditory cortex. Evaluation of the methods of differentiation of variola and alastrim viruses. For low instep circumference, age did not prevail significantly over Body Mass Index. Interaction between viruses and platelets: requirement of haemolytic activity for platelet aggregation induced by paramyxoviruses. In this situation, the possibility of intestinal necrosis expose the patient to a possible fatal outcome. Value of activities and participation glyburide dose route of patients with circulation diseases.

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