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Adalate (Nifedipine)

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Adalate is used to treat high blood pressure or angina (chest pain). For high blood pressure: Adalate works by relaxing and expanding the blood vessels. This makes the blood flow more easily and lowers blood pressure. Lower blood pressure reduces the strain on your heart. For angina: Adalate works by relaxing and expanding the arteries supplying the heart. This allows more blood and oxygen to reach the heart and decreases the strain on it. Your angina attacks will be less severe and less frequent if there is less strain on the heart.

Other names for this medication:
Adefin, Adipine, Afeditab, Calchan, Cardifen, Cardiosol, Cardipin, Coral, Cordafen, Cordipin, Corinfar, Depine, Emaberin, Menoprizin, Myogard, Nedipin, Nidilat, Nidipine, Nifecardia, Nifedel, Nifediac, Nifedin, Nifedipina, Nifedipine, Nifelat, Nifeslow, Nifezzard, Niften, Nilol, Noviken, Pressolat, Sidalat, Tensopin, Tredalat

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Adalate PA 20. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Adalate and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Adalate dosage information

Side effects

The most common side effects associated with Adalate are:

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Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

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Recent advances in the treatment and management of asthma have suggested that leukotriene (LT) receptor antagonists may be very beneficial as a second generation therapy with steroid-sparing properties and negligible side effects. Until recent times one of the most studied behavioural correlates of endogenous analgesia was stress-induced analgesia, in which the activation of endogenous opioid systems is known to be involved. The purpose of an external quality assessment (EQA) is to evaluate the analytical capability of clinical laboratories, identify differences among the laboratories and improve analytical quality. We found that one MPK-1 signaling-responsive gene encoding a C2H2 zinc finger protein plays a role in meiotic chromosome segregation downstream of MPK-1. Biochemical quantitation of PM2 phage DNA as a substrate for endonuclease assay.

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Identification of ethylene-mediated protein changes during nodulation in Medicago truncatula using proteome analysis. This study evaluates the dosimetric benefits and feasibility of a deep inspiration breath-hold (DIBH) technique in the treatment of lung tumors. The proportion of saturated fatty acids in adipose tissue was highest in Finland, intermediate in Scotland, and lowest in Italy. It is important to quantify how comparative genomics can improve computational detection of such modules. A subject who does not know the word will pronounce it false, i.e., according to the German pronunciation rule. The validity of the polygraph with hypnotically induced repression and guilt. HS families were also less likely to be dissatisfied with their pediatric primary care.

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To elucidate the role of VEGF in the angiogenesis of these experimental tumors, the effect of okadaic acid on VEGF gene expression was examined. The need to improve quality, rigour and dissemination of operations research. This article outlines the researches about using traditional Chinese medicine in the treatment of PF. This study evaluated the long-term cost-effectiveness of insurance coverage with imatinib as the first-line treatment for patients with CML in China from a societal perspective. The allele frequencies were determined based on diabetic medicine glimepiride typing of 242 genetically independent canine individuals from 72 breeds.

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Onset of the circulation is normally a progressive periphery-center phenomenon, and high levels of oxidative stress in the periphery may induce formation of the chorion laeve. Serious adverse events (SAEs) were reported by investigators and compiled in a pharmacovigilance database for all patients enrolled in the EAP. Compound 6j demonstrated efficacy in a mouse xenograft experiment. We retrospectively reviewed the medical records of all patients diagnosed with placenta accreta admitted to our tertiary center from January 1993 through December 2002. Cell divisions directly related to formation of stomates and of vascular tissue from their respective precursors occur throughout the period of leaf extension, so that differing tissue patterns reflect superposition of cycling related to cell differentiation on more general tissue proliferation. Longitudinal and structural neuroimaging studies show that patients with schizophrenia that converted to psychosis were found lipitor 80 mg tablet to have progressive gray matter loss in the cortex. Pancreas-preserving biliary amputation has been developed as an organ-preserving procedure alternative to pancreatoduodenectomy.

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Multiple sclerosis (MS) is an incurable chronic disease that predominantly affects young adults. Around materials and on its surface cell grew well with good morphology. When MgSO4 is used, systemic hypotension can be adequately controlled with ionotropes. Colicin D is a plasmid-encoded proteinaceous toxin which kills sensitive Escherichia coli. At present, surgical treatment offers the only chance of cure and therefore, early clinical and genetic detection and prophylactic surgery in subjects at risk are the main therapeutic goal. Anatomic Anterolateral Ligament Reconstruction Improves Postoperative Clinical Outcomes Combined with Anatomic Anterior Cruciate tenormin atenolol 25 mg Ligament Reconstruction. A dominant-negative form of the Ciona FGF receptor suppresses the formation of polarized actin-rich protrusions in notochord cells, resulting in defective notochord intercalation. A search for disease gene linkage revealed that a locus for autosomal dominant retinitis pigmentosa (adRP) known as RP17 resided in that region, and Northern blot analysis showed that hDGK epsilon was expressed in human retina. We review the entity and report two new cases, one a casual finding in a 49-year-old man and the other in a 63-year-old woman who presented with occasional bloody sputum.

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Moreover, clonazepam may exert its antiabsence actions through this mechanism. Effect of self-association and protein binding on the photochemical reactivity of triarylmethanes. Review: antiviral agents reduce risk of influenza in healthy adults and alleviate symptoms faster than placebo. reinhardtii cyclophilin transcript and protein levels during low-CO2 adaptation. NT3 induced a series of intracellular responses including enhancement of phosphorylation of Erk1/2 or Akt and increase of expression of oligodendrocyte lineage gene (Olig)-1, a transcriptional factor known to participate in oligodendrocyte development. The presence of speckle in ultrasound images aygestin 5 mg side effects makes it hard to segment them using active contours. Three EAS units, an electromagnetic plate at a library, a luggage control unit, and an antitheft gate, showed E fields reaching 658-1,069 V/m. The optimal strategy for abdominal wall reconstruction in the presence of a stomal-site hernia is unclear.

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This gradient is related to the metabolic activity of the thick ascending limb of Henle and the countercurrent vascular architecture, and may be relevant to a variety of physiological phenomena involved in volume, electrolyte, and acid-based homeostasis. Adinazolam, a new triazolobenzodiazepine, and imipramine in the treatment of major depressive disorder. Galacto-oligosaccharides potentially attenuate colonic inflammation by two mechanisms: through beneficial effects on intestinal microflora and by increasing the colonic short-chain fatty acid concentration. Detection of non-dipper hypertensives in clinical practice: does it really matter?. We examined memory performance and cortical source localization of old/new effects in a source memory task in obsessive-compulsive disorder (OCD) patients by employing an equivalent current dipole (ECD) model using EEG and a realistic head model. The diagnosis of cancer may lead to psychological distress with anxiety and depression as the most prevalent symptoms. This review provides a practical summary of the updated lexicon, including selective illustrations with original clinical images, a discussion of overarching concepts, and examples of current clinical applications. Dieting and weight loss do not affect on the platelet serotonin 5-HT2A receptor. Here, we used FGF-2 transgenic mice (TgFGF2) to study the effects of endogenous FGF-2 overexpression on susceptibility to seizures and to the pathological consequences of seizures.

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Early decompression may prevent permanent recurrent laryngeal nerve injury and airway obstruction. Regulation of collecting duct AQP3 expression: response to mineralocorticoid. The ecdysoneless (ecd1ts) mutation disrupts ecdysteroid synthesis autonomously in the ring gland of Drosophila melanogaster. Thunderclap protonix dosing gi bleed headache and normal computed tomographic results: value of cerebrospinal fluid analysis. We exploited variations in a gene encoding a protein with calcium-binding motifs (GPA) and in the major capsid protein (MCP) gene to assess allelic and genotypic richness within E.

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From an analysis of 40 electrocardiograms (20 before and 20 after dialysis) of a further 17 patients it was found that the height of the T wave is a good index of the plasma potassium level. To report the experience with gynecologic laparoscopic surgery at the Temuco Regional Hospital. Single-strand conformation polymorphism and sequencing did not identify any mutations in the DNA-binding domain of core-binding factor alpha 1. The Nonparametric variance statistics method was used to analyze the correlations between clinical breast cancer tissue of BCRP expression and drug resistance. We recently reported that phagocytosis of apoptotic cells inhibits the release of inflammatory cytokines by human macrophages.

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CVD risk factors and health outcomes persist among American Indians even as some risks (e.g., smoking) appear to be stabilizing or even declining in the general US population. It allows for easy control of the electron temperature (2-3.8 eV) and density ( approximately 10(9)-10(10) cm(-3)) by removing either of the two hexapoles or by varying the separation distance between the two hexapoles. Here, we characterise a novel moduretic drug FOXJ1 target, Cfap157, that is specifically expressed in motile ciliated tissues in mouse and Xenopus in a FOXJ1-dependent manner. Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase. It incorporates empirical rates for formation of secondary and tertiary structure. The present paper reports a questionnaire study regarding sleep and behaviour in a group of 29 subjects with PWS, compared with an age- and gender-matched control group. In these types of lesions, the subepithelial infiltrate varied in intensity but was mainly composed of T-lymphocytes reactive with anti-Leu 3a antibodies.

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