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Adamon (Tramadol)
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Adamon

Adamon is a centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults. Adamon is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine.

Other names for this medication:
Bolodol, Bramadol, Contramal, Decotram, Didol, Gemodol, Ibudol, Madol, Mobiya, Nobligan, Opiran, Paxmax, Pentazen, Relidol, Rimol, Rybix, Supridol, Tacil, Takol, Taramol, Traceta, Tramache, Tramacip, Tramagesic, Tramak, Tramared, Tramasol, Tramataur, Trambax, Tramdop, Tramoflex, Tranat, Trandy, Transic, Tridol, Tromfil, Ultrax, Unidol, Urgendol

Similar Products:
Zyvox, Silagra, Mobic, Antabuse, Sovaldi

Also known as: Tramadol

Description

{name} (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

{name} is used to treat moderate to severe pain in adults.

The extended-release form of tramadol ({name} ER) is for around-the-clock treatment of pain. {name} ER is not for use on an as-needed basis for pain.

Dosage

Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Adamon: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Adamon is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Adamon dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.

Storage

Store Ativan at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Adamon is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Adamon are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Adamon ER if you are allergic to it, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Adamon ER should not be given to a child younger than 12 years old. Adamon ER should not be given to anyone younger than 18 years old.

Do not give Adamon ER to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Adamon ER. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

Tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use Adamon ER during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using Adamon ER if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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Evaluation of Freeze-Dried Dura Mater Allograft as a Collagen Based Barrier (an experimental animal study). Pharmacological inhibition of AKT in human melanoma cell lines substantially reduced the expression of MelCAM. Effect of Terminalia arjuna bark powder on some diagnostic enzymes in buffalo (Bubalus bubalis) ingesting arsenic contaminated water and fodder. In this paper we investigate the linear instability of a compound inviscid liquid jet falling under gravity in a surrounding gas with respect to nonaxisymmetric waves. We show that TMS reduced the synchronization error when delivered to the vPMC.

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In order to regulate the apoptosis induced by Fas-FasL system, a soluble isoform of mouse Fas was cloned from thymocytes of immature mice with the primers designed according to the full-length Fas cDNA sequence in the GeneBank. After topical treatment with norepinephrine or stimulation of norepinephrine-containing afferents from locus coeruleus, there was a striking increase in the number of Purkinje cells with strong cyclic adenosine monophosphate reactivity. The radiological appearance of the cementless ALLOCLASSIC SL-stem, implanted in patients with primary osteoarthritis of the hip and aged at least 80 years at time of surgery, was investigated. Although, PAVM is a rare cause of haemothorax, the diagnosis should still be considered and transpleural ultrasound can detect these malformations non-invasively by the bedside. The aim of the present study was to investigate what kind of factor(s) is associated with this spontaneous survival of eosinophils.

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Eight samples of normal vulval tissue were selected from the excision margins of resected vulval biopsies. Recent epidemiological studies raised a concern for male reproduction given their observations of reduced sperm counts and altered semen quality. Effect of pharmacological agents on human keratinocyte mitosis in vitro. Ultrastructurally, the rods closely resembled those described in human nemaline myopathy. Spleen cells obtained from mice cured by Th1-cell therapy produced high levels of IFN-gamma, while spleen cells from mice cured by Th2-cell therapy produced high levels of IL-4. The present results are consistent with the conventional delta-value analysis of the second moment of probability. However, there exist multiple and effective management options for statin intolerant patients. First, these results indicate that the T4 molecule plays an essential role in T-B cell interaction even when it is not absolutely required for T cell proliferation. This retrospective study analyzes variation in prostate-specific antigen (PSA) levels in 129 males who were not diagnosed with prostate cancer or other known malignancies. beta-acetoxy-cycloart-25-en-24-one (1a) and glutinol (6), lupenone (7), dammaranodienol (9), cycloartenol acetate (10), 24-methylenecycloartanol acetate (11) and beta-sitosterol (12), isolated previously, were evaluated for their antiviral activities against Herpes simplex virus (HSV) and African swine fever virus (ASFV).

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The absolute configurations of (S)- and (R)-ACPA were established by X-ray crystallographic analysis of a protected (1S,2S,5S)-2-hydroxy-3-pinanone imine derivative of (R)-ACPA. Strain on the LUCL was measured in situ during extension and flexion with the forearm in supination, pronation and neutral. Survival after stenting in saphenous vein grafts is similar with direct and conventional techniques, although there was a tendency toward a lower incidence of myocardial infarction with the former. We analyzed the potential role of hepatic macrophages in acetaminophen hepatotoxicity by examining the effects of modulating the activity of these cells on tissue injury. Cue integration with categories: Weighting acoustic cues in speech using unsupervised learning and distributional statistics. Liver fat accumulation as a barometer of insulin responsiveness again points to adipose tissue as the culprit. With new knowledge of the structural similarities and relationships between related antibiotic biosynthesis pathways, the possibility of directed manipulation of specific genes to allow synthesis of novel antibiotics is now possible. Screening Hodgkin lymphoma survivors for radiotherapy induced cardiovascular disease. The transanal pull-through consists of a rectal mucosectomy, resection of the aganglionic bowel and a colo-anal anastomosis.

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Furthermore, monoclonal antibodies to either bFGF or FGFR-2 attenuated the increased proliferation of HUVECs exposed to 60/20 mm Hg cyclic pressure. The synergism/antagonism for lowering the stable values of dynamic IFTs in surfactant/alkali/hydrocarbon and surfactant/alkali/acidic model oil systems depends on factors that can change the EACN/n(min) value, such as the oleic acid in the oil phase and the n(min) values of surfactant and alkali. After all, our results could not confirm the static magnetic field effect. When accompanied by signs or symptoms that are compatible with androgen deficiency, treatment with testosterone should be considered in older men without evidence of prostate or breast cancer. This paper presents a multi-criteria based tool for assessing the relative impact of diffuse-source pollution to the Great Barrier Reef (GBR) from the river basins draining into the GBR lagoon. This paper explores the design of a BCI that can adapt to these short-term changes. In an effort to clarify the extent to which the psychostimulant methylphenidate has abuse potential, the existing published evidence has been reviewed and is summarized here, with an emphasis on delineating a number of related but independent issues that are often confused. Development of the Physical activity and Your Nutrition for Cancer (PYNC) smartphone app for preventing breast cancer in women. Desmoplastic fibromas are rare, benign, but aggressive lesions, affecting predominantly young people, with an affinity for the mandible. Many bacteria are demonstrating increasing levels of resistance to commonly used antibiotics.

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Hence, we promote the application of ICS to high-throughput genotype data in addition to the established PCA. As a consequence of the prolonged training with the brief perturbations, the M2 component of the electromyographic (EMG) response of the biceps and triceps muscles became gradually smaller, and finally disappeared. Ion exchange chromatography and hydrophobic chromatography play a central role in the purification scheme. The aim of this review was to identify the best available evidence on the effectiveness of using simulated learning experiences in pre-licensure health profession education. Extracorporeal shock wave lithotripsy of urolithiasis in patients with urinary diversion. The definitive obturator was inserted and evaluated for fit, function, and esthetics and was successfully delivered at the second visit. The ability of glyceollin II to induce osteogenic differentiation in ASCs and BMSCs indicates that glyceollins hold the potential for the development of pharmacological interventions to improve clinical outcomes of patients with osteoporosis. An isolated transarterial approach through the right femoral artery was used.

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The reaction sample is then flowed through the capillary cell of a single molecule detector. Forced expression of PTTG-1 by transient transfection stimulates bFGF and VEGF expression as well as changes the expression pattern of cell cycle proteins. It is therefore concluded that alpha-h-ANP is the only form of ANP circulating in human plasma. This might also avoid the problems of adaptation and the need for detailed investigations of pelvic nervous and vascular function. The age of onset of symptoms ranges from infancy to the geriatric age. In vitro genotoxicity and mechanistic studies demonstrated a mutagenic effect of bitumen fume condensates (BFC) and some data suggested that the polycyclic aromatic hydrocarbons (PAH) analysed were not the major genotoxic compounds in bitumen fume condensates. Phr-EGFP migration to CPD sites and redistribution after photorepair was followed, and shown to present similar kinetics in normal or DNA-repair-deficient cells. To identify vascular and dosimetric predictors of symptomatic T2 signal change and adverse radiation effects after radiosurgery for arteriovenous malformation, in order to define and validate preexisting risk models.

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Building materials as intrinsic sources of sulphate: a hidden face of salt weathering of historical monuments investigated through multi-isotope tracing (B, O, S). The Management of Symptomatic Cerebral Developmental Venous Anomalies: A Clinical Experience of 43 Cases. The results of using this MIPO approach for humeral shaft fractures in 4 patients were also reviewed. This pathogen is able to infect basidiocarps when surface-inoculated on mushroom casing soil. Although this condition is usually benign, there are other potentially fatal conditions, which often present similarly and clinically are difficult to differentiate from this entity. A comprehensive systematic review of the impact of planned interventions offered to pregnant women who have requested a caesarean section as a result of tokophobia (fear of childbirth). The micromechanical environment of intervertebral disc cells determined by a finite deformation, anisotropic, and biphasic finite element model. Studies have shown that functioning myocytes can be derived from stem cells in vitro and engrafted into infarcted areas of heart where they develop into functional adult like cardiomyocytes with action potentials and capacity for beta adrenergic and muscarinic regulation. These results suggest that RES can effectively inhibit lung cancer progression by suppressing the protumor activation of TAMs.

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Innate BALB/c enteric epithelial responses to Trichinella spiralis: inducible expression of a novel goblet cell lectin, intelectin-2, and its natural deletion in C57BL/10 mice. We feel that multidisciplinary triage performs a useful function in our department enabling us to reduce waiting times. The unforced BZ reaction shows both spatially uniform oscillations and rotating spiral waves, while the forced system shows patterns such as standing-wave labyrinths and rotating spiral waves. Research dissemination and utilization improving care at the bedside. Propagules (caryopsis plus glumes) from a diallel cross among eight genotypes of Anthoxanthum odoratum were weighed to asses the relative contribution of nuclear, reciprocal, and environmental effects to propagule size. Conversion of beta-human atrial natriuretic polypeptide into alpha-human atrial natriuretic polypeptide in human plasma in vitro. Comparing the in vitro threshold values for griseofulvin in human and rat lymphocytes with in vivo NOAEL/LOAEL in bone marrow/gut/erythrocytes suggests that the in vitro human system is the most sensitive. Haemophilus influenzae, the second cause of bacterial meningitis in children in Madagascar. Falls in older adults are associated with low education levels, regular to very bad self-perceived health, visual impairment, and recurrent falls. Stability of isoflavones in soy milk stored at elevated and ambient temperatures.

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A novel swine origin influenza virus (S-OIV) is continue to spread worldwide and a global declaration of 2009 influenza pandemic was made by World Health Organization (WHO) June 2009, this along with approaching the winter season at the northern hemisphere, increase the interest to provide a quick, easy, affordable and available point of care testing for S-OIV. On days 207 to 209, fetuses were recovered from heifers and used for testing. However, some types of displacement are desirable for local government. Thus, blood PLR and NLR would be helpful as a prognostic tool before radical lung cancer surgery. The simulated treatments are subjected to systematic and random errors that are either similar to the anticipated errors or unpredictably larger in order to critically evaluate the performance of these three adaptive strategies. Significant intrafamilial variability in the clinical expression of this syndrome is evident. Should QTN be treated differently than markers at linkage disequilibrium with QTL in genetic evaluation programs?. The insulin-glucose ration in children with islet cell tumors of the pancreas. Volumetric and single-sample collections revealed similar patterns of can ovral l be used as emergency pill change in urinary FE values with varying DCAB, except for calcium and magnesium.

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A newborn Japanese girl with no family history had a duplicated thumb on her left hand. To investigate in human and porcine isolated ciliary bodies the effect of acetazolamide and epinephrine on ciliary transepithelial ionic currents (a parameter linked to aqueous humor production). This study indicated that local muscles such as the MF and TrA may be related to pelvic tilting. Recurrent acute otitis media associated meningitis in a patient with a contralateral cochlear implant and bilateral cochleovestibular dysplasia. Crown survivals depend on type of support, type of fatigue test conducted, crown structure, and veneering method.

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