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Alendix (Alendronate)
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Alendix

Alendix is used to prevent and treat certain types of bone loss (osteoporosis) in adults. Osteoporosis causes bones to become thinner and break more easily. This medication works by slowing bone loss. Alendix belongs to a class of drugs called bisphosphonates.

Other names for this medication:
Alant, Alendix, Alendronate, Alenost, Bifosa, Denfos, Osteofos, Ostogee, Poronil, Ralenost, Restofos, Zophost

Similar Products:
Sovaldi, Periactin, Ticlid, Prandin, Catapres, Pamelor, Risperdal

Also known as: Alendronate

Description

{name} (alendronate) is a bisphosphonate (bis FOS fo nayt) medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures.

{name} is used in women to treat or prevent osteoporosis caused by menopause and in men and women to treat osteoporosis caused by taking steroids.

{name} is also used to increase bone mass in men who have osteoporosis, and to treat Paget's disease of bone in men and women.

Dosage

Take Alendix exactly as prescribed by your doctor. Alendix is taken either once daily or once per week. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take Alendix first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine. If you take this medicine only once per week, take it on the same day each week and always first thing in the morning.

Take with a full glass (6 to 8 ounces) of plain water. Do not use coffee, tea, soda, juice, or mineral water. Do not eat or drink anything other than plain water.

Do not crush, chew, or suck on an Alendix tablet. Swallow the tablet whole.

For at least 30 minutes after taking Alendix:

Do not lie down or recline. Do not take any other medicine including vitamins, calcium, or antacids.

Pay special attention to your dental hygiene while taking Alendix. Brush and floss your teeth regularly. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using alendronate.

Alendix is only part of a complete program of treatment that may also include diet changes, exercise, bone mineral density testing, and taking calcium and vitamin supplements. Follow your doctor's instructions very closely.

Store at room temperature away from moisture and heat.

Your doctor will determine how long to treat you with this medicine. Alendix is often given for only 3 to 5 years.

Detailed Alendix dosage information

Overdose

Drink a full glass of milk and seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Do not make yourself vomit and do not lie down.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alendix are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Alendix if you are allergic to alendronate, or if you have:

low levels of calcium in your blood (hypocalcemia); or problems with the muscles in your esophagus (the tube that connects your mouth and stomach).

Do not take Alendix if you cannot sit upright or stand for at least 30 minutes. Alendix can cause serious problems in the stomach or esophagus. You must stay upright for at least 30 minutes after taking this medicine.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

trouble swallowing; problems with your stomach or digestion; low levels of calcium in your blood; a dental problem (you may need a dental exam before you begin taking Alendix); kidney disease; or any condition that makes it hard for your body to absorb nutrients from food (malabsorption).

In rare cases, this medicine may cause bone loss (osteonecrosis) in the jaw. Symptoms include jaw pain or numbness, red or swollen gums, loose teeth, or slow healing after dental work. The longer you use Alendix, the more likely you are to develop this condition.

Osteonecrosis of the jaw may be more likely if you have cancer or received chemotherapy, radiation, or steroids. Other risk factors include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem.

Alendix has also been reported to cause fractures, or broken bones, in the large bones of the leg. Tell your doctor if you have any leg or groin pain while using Alendix.

Talk with your doctor about the risks and benefits of using this medication.

It is not known whether Alendix will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Stop using the medicine and tell your doctor right away if you become pregnant.

It is not known whether alendronate passes into breast milk or if it could harm a nursing baby. Ask your doctor about any risk.

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All the paraclinical test were normal, except the electromyogram, showing a classical pattern of lower motor neuron disease, and the auditory brain stem response with absence of the main components of this evoked response, as expression of VIII cranial nerve damage. The results also show that under some circumstances, nucleotide sequence differences between alleles found within one individual can be distinguished from DNA sequence variation caused by postmortem DNA damage. The target is made of point-diffraction sources that emit two spherical wave fronts, whose interference is monitored by the photodetectors. We therefore aimed to develop an IC/PBS diagnosis method using a cystoscope with a narrow-band imaging (NBI) system that can detect mucosal angiogenic lesions. Three chronic studies using the sternotomy approach were performed. Multiple literacies: Linking the research on bilingualism and biliteracies to the practical.

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Elastin composition of human skin chronically exposed to the sun. The synthesized MnP had the expected molecular mass (43,000Da) and catalyzed the oxidation of 2,6-dimethoxyphenol (DMP) in the presence of hydrogen peroxide and Mn(II). The purpose of this study was to estimate the regional relative blood volume (rBV) in head and neck tumors, which is useful for tumor staging and tumor biopsy. The clinicopathologic features of 108 patients with thymoma removed surgically were retrospectively reviewed. Superconductivity in the antiperovskite Dirac-metal oxide Sr3-xSnO.

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Conceptual issues in assessing responsibility for actions symptomatic of mental illness. To do so, we suggest, females formed protective relationships with male co-defenders. Neurons, astrocytes, oligodendrocytes and microglial cells all undergo pathological modifications in the onset and progression of ALS. Application of vertebroplasty, neuronavigation and kyphoplasty in the treatment of multiplex osteoporotic vertebral fractures--case report. Analysis of the North American Immune Tolerance Registry (NAITR) 1993-1997: current practice implications. Characterization of sugar binding by the mannose receptor family member, Endo180. CB1 receptor density and CB1 receptor-mediated functional effects in rat hippocampus are decreased by an intracerebroventricularly administered antisense oligodeoxynucleotide. Optimization of a solid-phase extraction method using copolymer sorbents for isolation of phenolic compounds in red wines and quantification by HPLC.

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Role of p14ARF and p15INK4B promoter methylation in patients with lung cancer: a systematic meta-analysis. Data collection automation and total quality management: case studies in the health-service industry. It has been possible to confirm the instability of glucuronide compounds when added to poorly stored equine urine samples. This is neoral dosing the first report indicating that CHM reduces the cytotoxicity induced by PGD2 or delta 12-PGJ2. lactis Supplementation in Gut Microbiota, Immunity, and Metabolism of Infant Rhesus Monkeys. The development of Plasmodium falciparum in experimentally infected Anopheles gambiae (Diptera: Culicidae) under ambient microhabitat temperature in western Kenya. Human immunodeficiency virus nef gene expression affects generation and function of human T cells, but not dendritic cells. Each EC1-4 molecule makes a helical curve allowing some torsional flexibility to the edifice.

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A metal oxide semiconductor field effect transistor (MOSFET) with its inherent high spatial resolution was used for penumbra measurements in a 120 kVp X ray beam. Based on these data, it is concluded that the efficacy of ginseng root extract is not established beyond reasonable doubt for any of these indications. 24 patients with typical angina and normal arteriogram and 30 normal controls were studied with 201Tl SPECT to evaluate uptake and washout. In this paper, we develop a Fourier-domain approach to full-matrix imaging based on the wavenumber algorithm used in synthetic aperture radar and sonar. Three databases were pooled and analyzed to determine which groupings of prognostic factors best predicted overall survival for patients with low-grade gliomas treated with surgery and immediate or delayed radiotherapy. In this study, we show that two entry-mediating envelope gp, gp B (gB) and gp H (gH), display determinants recognized by TLR2.

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p21 induction in the LNCaP cell line reached a peak 7.5 h post-irradiation. These findings support the notion that the differential regulation of distinct potassium channel beta subunits, in the developing mouse nervous system, may confer the functional diversity required to mediate both neuronal survival and maturation. Myoglobin-containing carbon-paste enzyme microelectrodes for the biosensing of glucose under oxygen-deficit conditions. Taken together, our data demonstrate that AIP1 functions as an endogenous inhibitor in VEGFR2-mediated adaptive angiogenesis in mice. Effects of dietary protein and energy levels on cow manure excretion and ammonia volatilization. We show the importance of finite particle size in microfluidic asymmetric continuous-flow diffusion arrays, specifically the critical nature of the particle size with respect to the barrier gaps. Organic matter, nitrogen, and lead in deposits correlated positively with the atrazine concentration in groundwater. Fine needle aspiration (FNA) biopsy can be used to reliably classify most conditions involving lymph nodes or, at least, significantly reduce the differential diagnosis. Extensive chromatin remodeling after fertilization is thought to take place to allow a new developmental program to start. Multiple studies have shown that for endocardial defibrillation, biphasic waveforms have a greater efficacy than monophasic waveforms.

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