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Alpraquil (Alprazolam)

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Alpraquil is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alpraquil is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alpraquil may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Aleez, Alprawin, Alsert, Alzac, Alzocum, Alzom, Alzoset, Alzot, Alzotime, Ambutech, Ansilumirm, Anxicalm, Anxico, Anxigo, Anzal, Balmusa, Benzax, Dexolam, Ecsit, Eurolam, Exprex, Fludep, Flunix, Imprax, Kaprolam, Mediprex, Meloprax, Nexlpra, Normatine, Optizole, Ozolam, Pifzot, Resolin, Restyl, Rezolam, Romipraz, Sinzolam, Tenil, Tenolam, Tenscure, Tenzorid, Xylonite, Zeecam, Zeftra, Zepro, Zodia, Zolax, Zopral

Similar Products:
Tricor, Noroxin, Furadantin, Nuvigil, Fosamax, Antivert, Kemadrin, Ambien, Eriacta

Also known as: Alprazolam


{name} (alprazolam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.

{name} is used to treat anxiety disorders and anxiety caused by depression.

{name} is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia).

It is dangerous to purchase {name} on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alpraquil XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alpraquil XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alpraquil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alprazolam in the elderly. However, elderly patients are more likely to have unwanted effects (eg, severe drowsiness, dizziness, confusion, clumsiness, or unsteadiness) and kidney, liver, or lung problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

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An increased level of H19 was also associated with poor clinical outcomes of cancer patients. When SP and A were aerosolized sequentially in the same experiment in two monkeys that had had IgE-mediated airway responses that had disappeared with time and in one monkey that had only had cutaneous reactivity to A, an airway response to A occurred. fumigatus clinical isolates are present in Nanjing, China, which is a new challenge to the clinical management of IA. Strains NO3A and NO2B, two newly isolated, nitrate-reducing bacteria (NRB) emerged as major community members. Update on acute myeloid leukemia stem cells: New discoveries and therapeutic opportunities. An unusual karyotypic observation on cultured cells from an owl monkey (Aotus trivirgatus). Six reports were included in the review of which three were randomized controlled trials. The Food and Drug Administration and National Cancer Institute will have enhanced abilities to perform high-quality postmarket surveillance and other research at lower cost and with faster speed. It was indicated that the introduction of suitable groups at the 2- and 3-position of the aromatic ring A or at the 9-position of the aromatic ring D could enhance the activity. The most pronounced changes of the quality of life of laryngectomized patients are seen at marital, familial, professional, business and communication aspects.

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The trappable population was composed almost entirely of adults, and the sex ratio was skewed significantly toward females. In this study we aimed to further investigate the role of the miR-302 cluster in multiple cancer signaling pathways using A-375 melanoma and HT-29 colorectal cancer cells. The acoustic behaviour of the closely related tetigoniid species Psorodonotus illyricus and Decticus verrucivorus have been invectigated by bioacoustical and behavioural methods. Stereological quantitation in cerebella from people with schizophrenia. We show that the interplay between the coupling strengths and the external noise controls the phase relations between the neurons in a counterintuitive way. Depressed beta-adrenergic receptor- and endothelium-mediated vasodilation in conscious dogs with heart failure. During maturation, the hormone-triggered inactivation of Myt1 depletes the soluble inactive Cdc2-cyclin B and the turnover leads to dissolution of the aggregates. Management of peripheral nerve defects: external fixator-assisted primary neurorrhaphy.

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Sorption isotherms were generated by measuring aqueous concentrations and by extracting the sorbed parent chemical or transformation products (e.g., estrone, androstenedione). The purpose of our analysis was to assess long-term sunitinib activity in the treatment of metastatic ASPS. On activated B cells GL1, rather than B7, is the predominant ligand for the T cell-activation molecule CTLA-4. Laser peripheral iridoplasty (LPIP) is an alternative and effective way of widening the angle recess in eyes that are affected by primary angle closure (PAC). Helicobacter pylori DNA was detected in 4 of 12 patients with CRS, but it was not detected in patients with concha bullosa. The uterine receptivity for blastocyst implantation in the rodents is activated by nidatory estradiol and is maintained for a restricted period. Examples include the mechanical transport of atoms carrying quantum information or the use of spontaneously emitted photons. Activation of Rho/Rac GTPases during cell signaling requires the participation of GDP/GTP exchange factors of the Dbl family. We briefly describe the ability to detect noncovalently associated complexes (e.g., double-stranded DNA) by electrospray ionization-mass spectrometry, and conclude with recent results that show the potential for using high-resolution Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry for characterization of biomolecules. Solid tumors synthesize a number of extracellular matrix-degrading proteases that are important for tumor progression.

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The appearance and increasing activity of the high K(m)-PDE coincides with the differentiation and growth of photoreceptor outer segments. Calcium homeostasis and the patogenesis and management of hypercalcemic disorders. Maintaining the momentum in EOH: issue 1 of the Journal of Industrial Hygiene and Toxicology, January 1936. Hair transplantation has been a highly effective technique in reducing wide foreheads and recontouring the hairline. Plethodon richmondi shenandoah occurs in at least three geographically isolated talus slopes in Shenandoah National Park, Virginia, U.S.A., each surrounded by a continuous population of Plethodon c. Effectiveness of preventive dental treatments by physicians for young Medicaid enrollees. We investigated the possible roles of the interleukin (IL)-15 and IL-15 receptor (IL-15R) system in a heightened state of B-cell activation and differentiation in intestinal mucosa with inflammatory bowel disease (IBD). This indicates that COP combined with mBHTK may be an optimal preservation technique for use with NHBD hearts. Antenatal care can be a key entry point within the health system for many women, particularly in low-resource settings.

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This paper reports on the satisfaction of over 470 patients with implant prostheses fabricated using a new and innovative implant design (Ankylos, Dentsply-Friadent, Mannheim, Germany). Expression of phosphorylated AKT was increased in PC-9 cells and inhibited by 0.02 microM gefitinib. This study was performed to determine the temporal relationship between CT attenuation, ADC value, and DWI signal intensity in acute cerebral ischemia. Intraretinal variation in opsin abundance consisted of greater expression of both RH2, and lesser expression of SWS1 and both SWS2A, opsin transcripts in the dorsal compared to the ventral retina. Primary stabbing headache (PSH) or ice pick headache is an infrequently studied, yet socially important problem facing children and adolescents.

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The results suggest that PTN functions in part through activation of protein kinase(s) in NIH 3T3 and NB41A3 cells. Nidogen and heparan sulfate proteoglycan: detection of newly isolated basement membrane components in normal and epidermolysis bullosa skin. Mediation analyses have been a popular approach to investigate the effect of an exposure on an outcome through a mediator. Novices have to learn to optimally control what their hands are doing in a real-world environment while looking at an image representation of the scene on a video monitor. Infrared spectroscopy is widely used to probe local environments and dynamics in proteins. Twenty-one patients aged 7 to 15 years with high myopic anisometropia had multizonal PRK in the more myopic eye and were retrospectively analyzed. However, intestinal mucosa also expresses liver-type FABP (L-FABP). Both conidiospores and mycelial cells resume normal protein synthesis after 60 min at high temperature. Since OC is known to be glycosylated, it is also possible that the measurement would be affected by high glucose conditions.

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One of these is KLK4, whose increased mRNA expression was identified as a poor prognostic marker in ovarian cancer. DNA was extracted from whole blood samples collected with diovan medication causes cancer informed consent. The differentiation of bradyzoites isolated from brain cysts (strains 76K and BQNC2) and grown in culture proceeded through intermediate stages which expressed both the specific markers of bradyzoites (P36, P34, P21, and P18) and a specific marker of tachyzoites (SAG1-P30). This herbivore attacked the most vigorous plants in a population, and numbers of attacks declined as ramets aged and senesced. Effects of 6-hydroxydopamine on an identified dopamine-containing neuron in the central nervous system of Planorbis corneus. Consumer testing before application deployment was reported in just over half of the studies.

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The substantial and steady decline of IHD mortality seen in most western countries in the past two decades was not observed in Hong Kong, which showed a plateau or slowly decreasing trend only in the past decade for both women and men. This region thus represents a new protein domain that we called T3S4 for Type III secretion substrate specificity switch. It seems that a decreased excretion of arsenic may contribute to the development of cystine calculosis. Mechanism of membrane curvature sensing by amphipathic helix containing proteins. Unexpectedly, we found that the ginger compounds and their structural analogs generally outscored other ligands at both sites.

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One of the proteins recognized by anti-idiotype antibodies is identical to a previously identified NLS-binding protein. In vitro studies with pyranine revealed that release depends substantially on the gelatin content of the matrices, which proved to be a useful tool as a release modifier. The potential application of these angiogenesis inhibitors is currently under intense clinical investigation. However, no data were presented about lipid values in patients and controls. Succinate detection by the bioelectrocatalyst was linear from 5 microM to 10 mM succinate. Anterior and posterior segments of the bovine eyes were sectioned and stained by the indirect immunofluorescence method with an anti-TSP-4 antibody. Tissue carnitine homeostasis in very-long-chain acyl-CoA dehydrogenase-deficient mice. If group singing is found to be effective and cost-effective it may offer an alternative means to maintaining the health of people in later life.

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There were no significant differences between the two groups in induction-to- can you take migraine medication with zyrtec vaginal delivery interval, mode of delivery, number of women delivering within 24 hours and neonatal outcomes. Strategies for nonradioactive methods in the localization of phosphorylated amino acids in proteins. Inhibition of hypoxanthine transport by chlorpromazine and SKF 525-A in cell culture. An overexpression of Bcl-xL protein in the KK1, one of the ATL cell lines, suppressed apoptosis by the 3rd day, however, apoptosis could not be prevented completely. We found that hypothermia both prevented ischemia-induced neuronal zinc accumulation and cell death. We investigate the effects of wavelength tuning on the diode spectrum on its corresponding Raman gain, and on pump-pump four-wave mixing in fiber having zero-dispersion wavelength coincident with the Raman pumps.

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Adverse events are a persistent and an important reason for admission to the ICU. Several subgroup analyses were performed, defined by anti-dementia medication use, baseline MMSE score, and DLB core features. The function of the liberated enzymes, hormones and inhibitors is far from being understood or even investigated. Elongation of chain A, described here for the first time, considerably improved the stability of the selected analogs. These drugs have a trough: peak ratio that approaches 1, and thus exert a uniform antihypertensive effect over the dose interval. (2) To identify factors predicting changes in diagnosis, and compare the long-term outcomes of various patterns of diagnostic shift. The recent researches have shown that cellular immune abnormalities are main reasons to cause PRCA. Superficial temporal artery biopsy obtained one week after starting steroids was positive for giant cell arteritis. Progression of changes (signs of FSG) was found in 19 children, in 2 children changes in repeated biopsy did not differ from those in first biopsy, and in one child regression was observed.

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Leptin and adiponectin levels in discordant dichorionic twins at 72 hours of age-associations with anthropometric parameters and insulin resistance. High-frequency interferon-gamma-secreting splenocytes specific for murine cytomegalovirus immediate-early-1 (IE-1) peptide 168YPHFMPTNL176 are insufficient to provide complete protection from viral challenge. Many ordered water molecules with long residence times are found at the intermolecular interfaces of loxitane 10 mg the complex. A note on the functional significance of phosphatases in the club cells of a fresh-water teleost, Saccobranchus fossilis. A propensity score model was developed to evaluate the survival of patients receiving intensive care treatment including targeted temperature management, compared with intensive care treatment not including targeted temperature management. Thus, it is critical to develop new post-processing techniques that can distinguish true identifications from false identifications effectively. The African cherry (Prunus africana): can lessons be learned from an over-exploited medicinal tree?. We sought to establish the feasibility and validity of the estimating ambulation capacity by history questionnaire (EACH-Q), a self-administered, four-item questionnaire that estimates walking capacity in patients reporting vascular-type claudication.

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Treatment of keratinocytes with epidermal growth factor results in an increase in Delta Np63 alpha expression at the mRNA level, which is abrogated by inhibition of PI3K but not mitogen-activated protein kinase signaling. The objective of this study was to assess short-term and long-term outcomes after valve replacement with biologic or mechanical prostheses in patients with preoperative end-stage renal disease on chronic dialysis. A cross-sectional study was conducted in a level III hospital on a sample of 194 postpartum women during the period from January to June 2015. Prevalence of seroreagents to FMDV in the cattle population in Poland: results of 9-year monitoring studies. Pretreatment with haloperidol, an antagonist of both D-1 and D-2 dopamine receptors, metoclopramide and molindone, the selective D-2 dopamine receptor antagonists, effectively antagonised bromocriptine-induced climbing behaviour. beta-Blockade slows or reverses the adverse effects resulting from chronic adrenergic stimulation.

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It should be used to treat patients with huge PLC at first choice. The overall purpose of this investigation was to evaluate whether measurement of the physical sensations (breathing effort) and affective response to these sensations of breathing (breathing distress) are consistent and valid. Lipid peroxidation of paroxysmal nocturnal hemoglobinuria (PNH) erythrocyte membrane. Here we tested the ability of this domain to self-associate under a variety of solution conditions. EPO was injected subcutaneously at a dose of 10,000 U, and venous blood samples were collected before and 2, 4 and 6 h after EPO administration. The influence of hypothermia on the development of neurogenic pulmonary edema. Vectors were constructed with deletions in the E1, E3, and/or E4 regions.

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During the evolution of the sinus disease persistent asthma develops. Physiological, subjective, and psychomotor measures were collected daily during each dosing cycle. Effective use of the efficacious treatments also depends on effective case-finding and providing treatment, which families and youths will take in adequate quantity and duration. Airway beta-defensin-2 gene transfer enhances the bacterial clearing of rat lung. Atomistic Monte Carlo (MC) simulations have been used to study a thermally induced phase transition in poly(alpha-octadecyl-beta,L-aspartate). Y-chromosome in situ hybridization was used to track donor cells in the livers. The parameters were evaluated on 50 denture wearers using semiquantitative scales and a recently described submandibular/sublingual saliva collector. caCdc42 also increased endocytotic activity of DC, whereas dominant-negative Cdc42 blocked it. We report one such case where a routine pre-implant radiographic assessment revealed a mixed periapical radiopaque radiolucent lesion in the right maxillary central incisor region.

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