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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprazolam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprazolam is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alcicalm, Aleez, Alpraquil, Alprasan, Alzep, Ambusyn, Azolam, Balzam, Calmef, Copax, Depoxit, Diprex, Ezoprax, Fultop, Hiprazole, Omelam, Ozolam, Procalm, Proprazolam, Romipraz, Somnarest, Tenzorid, Xanti, Zopic, Zopral

Similar Products:
Zyloprim, Imdur, Crestor, Viramune, Symmetrel, Leukeran, Uroxatral, Moduretic


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

Measure the liquid form of Alprazolam with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not swallow the orally disintegrating tablets whole. Allow it to dissolve in your mouth without chewing.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

You may have seizures or withdrawal symptoms when you stop using Alprazolam. Ask your doctor how to avoid withdrawal symptoms when you stop using Alprazolam.

Keep track of the amount of medicine used from each new bottle. Alprazolam is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprazolam dosage information

Side effects

The most common side effects associated with Alprazolam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

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HaCaT cells were cultured with or without various cytokines for 24 h and RT-PCR was performed using these cells to evaluate MDC mRNA levels. Such an interaction might play an important role in the behavior of lymphocytes in tissues. Training response inhibition to reduce food consumption: Mechanisms, stimulus specificity and appropriate training protocols. Comparing survival of a sample to that of a standard population. However, the marginal ingestion rate (amount consumed/unit of handling time) did not differ with prey size throughout a 10-tadpole catch sequence. In addition, 4.7 T magnetic resonance imaging (MRI) revealed that C225-USPIO had a capacity to accumulate in the CNE1 cells, with a resultant marked decrease in MRI T2-weighted signal intensity over time. A 21-year-old woman and a 41-year-old woman with worsening headaches, visual obscuration or diplopia were treated for pseudotumor cerebri associated with transverse venous stenosis. Understanding gene function in the developing pancreas is a major issue for pancreatic cell therapy. Obstruction of the ureter after extracorporeal lithotripsy in cases of a single kidney.

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Use of monoclonal antibodies to lipopolysaccharide for antigenic analysis of Coxiella burnetii. Conventional microscopic methods (thick-smear, saline and iodine solutions) were used to identify parasites in stool samples of 301 children attending day care centres. Genetic predisposition and oxidative stress caused by exogenous and endogenous factors can contribute to abnormal differentiation and hyperproliferation of keratinocytes, accordingly the development and maintenance of psoriasis. The effects of blood metals on cardiovascular autonomic function have not been studied extensively. The position and distribution of the vlhA pseudogene regions, and their relationship with the expressed gene, have not been investigated.

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Hypoglycemia resolved after alleviation of the congestive heart failure. A novel role for cholecystokinin: regulation of mesenteric vascular resistance. It was first used during cardiopulmonary bypass to inhibit plasmin-induced complement activation. Using national registry data, the number of new cases of HER2-positive breast cancer patients per year was estimated. but also ways to circumvent encountered issues with HDR insertions by the development of non-homologous dependent strategies. Current and future therapeutic strategies to target inflammation in stroke. Bone density was measured every four months for two years by photon absorptiometry.

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N-sulfation of heparan sulfate with microsomal fraction of endometrium of rabbit uterus. This approach is based on entirely different principles than the previous approaches. Randomised trials comparing chemotherapy regimens for advanced non-small cell lung cancer: biases and evolution over time. It was investigated the dynamic of postprandial glycaemia in 38 patients with fatty hepatosis and obesity after ingestion of breads, macaroni products, grits and legumes and it was determined its glycaemic index in the present study. Recent events of war, terrorist attacks, and mail-borne anthrax exposure have produced increasing awareness of potential bioterrorism attacks in the United States and other parts of the world. Moreover, the influence of the layer thickness and of the stationary phase porosity on the performance and on the sample load capacity was investigated. These results argue strongly for a major role for the zinc ion in amino acid discrimination by CysRS, where the tight zinc-thiolate interaction and the strict structural geometry of the metal ion are sufficient to reject serine by more than 20,000-fold at the binding step. However, cells showed a remarkable loss of viability in stationary phase. The structure of the O-specific polysaccharide from Ralstonia pickettii. Furthermore, although 5 of 20 men who received Sildenafil had an increase in penile blood flow without sexual stimulation, only 7 of 20 were responders to Sildenafil after take home medication.

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Observations show that physicians continue to carry out double entry of orders because it supports an invisible quality control, and because various readers of orders have different needs for details. The same result was observed for systematic clinical breast examination. The functional roles, structures, synthesis, analytical aspects, and clinical significance of leptin, ghrelin, adiponectin, and resistin are summarized. The control group comprised 116 healthy schoolchildren 5 to 12 years old. In the present research we examined the development of sensitivity to two musical relations significant in Western tonal music, the semitone and diatonic structure. The standard RCA2 model overpredicts cloud cover and downwelling longwave radiation, during the Arctic winter. It is important to verify the high index of patients lost to follow-up, particularly in G1. The development of negative phototaxis and nocturnal activity is correlated with the demands of the young larvae for current and food. This finding is further evidence that this aspect of corneal epithelial cell differentiation and maturation is tightly controlled with little variability between individuals even if a corneal condition is present. To understand the translocation of hCT(9-32) across plasma membranes, we investigated its interactions with phospholipids and its interfacial structure using model lipid monolayers.

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In order to address the needs of the indigenous population in particular, a range of service changes was implemented to improve outcomes. Implementation research: a mentoring programme to improve laboratory quality in Cambodia. Neither deletion of LAC1 nor overexpression of YPC1 had a detectable effect on wild-type life span. The expression of EGFP was tested by fluorescence microscope and flow cytometry. gp 140, the C3d/EBV receptor (CR2), is phosphorylated upon in vitro activation of human peripheral B lymphocytes. With such a vast array of potential applications, there is a great need to understand the exact mechanisms controlling the maintenance of pluripotency, and the distinct cues signaling these cells to differentiate towards lineages of interest.

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In our recently proposed endovascular approach to produce bifurcation aneurysms in the rabbit, the right common carotid artery (CCA) is surgically exposed and distally ligated, and a sheath is advanced retrogradely into the CCA, the base of which is proximally occluded using a Fogarty balloon. Older maternal age may predispose offspring to ESRD through mechanisms that differ for DESRD versus non-DESRD, and that may relate to ethnicity. Uranium is a heavy metal which, following accidental exposure, may potentially be deposited in human tissues and target organs, the kidneys and bones. It was hypothesized that higher fecundity led to increased scenescence through a higher metabolic rate. These studies suggest: 1) that the MAb against BB-1 binds a functional epitope on a molecule distinct from B7 as detected on activated keratinocytes in vitro and in vivo and 2) that keratinocytes in skin and epithelial cells in thymus can express cell-surface molecules that might mediate T-cell co-stimulation via CD28. The collected spectra were processed with partial least-squares discriminant analysis (PLS-DA) to build the classification models. The area-specific regional increase in specific binding density in aged rats was significantly correlated with the impairment of their behavioral performances in the Morris water maze task. Simulations of human lysozyme: probing the conformations triggering amyloidosis.

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Pancreatic heterotopias: clinicopathological analysis of 18 patients. 1H, 13C, and 15N resonance assignments of the 17 kDa Ap4A hydrolase from Homo sapiens in the presence and absence of ATP. Avian sarcoma virus transformed hamster cells resistant to bromodeoxyuridine and deficient in thymidine kinase activity. The results suggest that atomic solvation parameters (ASP) widely used in continuum hydration models might be dependent on ASA for polar/charged atoms under consideration. The other lineage is estimated to have originated in southern Mesoamerica about 3 Myr later, apparently piggy-backing on the pre-existing mutualism. A computerized literature search was conducted to identify articles pertaining to rFVII use for refractory bleeding in adult, nonhemophilic, surgical patients. Atrophy of the brain stem and cerebellum has also been reported.

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Determination of the helix and beta form of proteins in aqueous solution by circular dichroism. Some of the main psychological research topics concerning chronic low back pain (CLBP) are critically discussed. This question is particularly relevant for Notch signaling, which coordinates neighboring cell fates through direct cell-cell signaling. A transformation from a predominantly heterogeneous to predominantly homogeneous nucleation takes place if the pore diameter is smaller than 65 nm. Determinants of help seeking and treatment seeking behavior of TB patients -gender perspective: systematic review. The second logistic regression analysis revealed all the previous items as powerful factors of crash probability, including the transportation of express freight and freezer. Cutaneous angiosarcoma of the scalp: a multidisciplinary approach. Morris water maze test and object who makes tricor drug recognition test revealed better learning, working memory and also better memory retention on artemisinin treatment.

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The TGF-beta signaling network plays a complex role in carcinogenesis because it has the potential to act as either a tumor suppressor or a pro-oncogenic pathway. TBT formed the principal butyltin species in sediment at all sites studied. The data were imported and analyzed using commercial statistical analysis software. Dilatation of the Chambers of the Heart Caused by a Mutation of Lamin Gene (LMNA). Among the oxaliplatin non-containing regimens, the cost-effectiveness of S-1 and capecitabine was superior to that of UFT/LV. When questioned about barriers, both patients and employers emphasized the importance of work-related factors such as sensory overload at the workplace and condition-related factors such as fatigue.

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The present findings are the first to provide promising evidence for the validity of a brief measure of suicide ideation frequency in a Hungarian population. The possibility of reducing symptomatic hypercalcemia and of maintaining total serum calcium concentrations less than 2.8 mmol/l with clodronate (dichloromethylene bisphosphonate) was evaluated in 28 patients with various types of malignant tumors. The effort involved in such a procedure is justified because it can help to avoid clinically relevant food allergens in some diflucan 150 mg dosing instructions cases and in others can prevent children from being exposed unnecessarily to diets that may be harmful to them. There is no evidence for the assumption that HES-associated renal impairment may be avoided by accompanying measures. Patients with posttraumatic stress disorder show decreased cognitive control: evidence from dichotic listening. Activation of PTEC by mediators released from infiltrating cells or resident kidney cells that induce tubular inflammation is the common final pathway in most chronic renal diseases. Isoproterenol, dopamine, and serotonin all produced significant increments in LHRH secretion. High doses of intravenous iron have a role in the treatment of a number of clinical situations associated with iron deficiency, iron deficiency anemia, and blood loss. There is common understanding, within the literature, that an inflammatory process at the tail of the pancreas may disrupt the spleen and result in such splenic complications.

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Genetic variability at the APOA1/C3/A4/A5 cluster periactin drug class has been examined in relation to lipid metabolism and cardiovascular disease risk. Bio::Phylo can interact with BioPerl, thereby giving access to the file formats that BioPerl supports. Low (average: 7 mmHg) CO2 gas pressure was employed during the procedure. Furthermore, for an applied current larger than Isw, we unveil the existence of two distinct thermal regimes. Gastric electrical activity in normal neonates during the first year of life: effect of feeding with breast milk and formula. Prey to predator size ratio influences foraging efficiency of larval Aeshna juncea dragonflies. Pharmacological interventions for people with depression and chronic physical health problems: systematic review and meta-analyses of safety and efficacy. At a hemodynamic wall shear rate, BT-20 and MDA-MB-468 breast cancer cells adhered to cytokine-activated human umbilical cord vein endothelial cells (HUVECs) but not to anti-E-selectin monoclonal antibody treated HUVECs, demonstrating that adhesion was specifically mediated by E-selectin. This work investigates the effects of pectins and pectic-oligosaccharides (POS) on the human colonic adenocarcinoma cell line HT29. Changes were also noted in the integrins on the migrating keratinocytes.

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At first VTE children manifested i) with a lower rate of pulmonary embolism, ii) a higher rate of cerebral vascular events or multiple VTEs, and iii) showed a higher proportion of unprovoked VTE compared to adolescents and adults. Community-dwelling college students from a large Midwestern university. Ram horn peptone as a source of citric acid production by Aspergillus niger, with a process. For many years, clinicians have is zyrtec a prescription drug accepted the fact that most medications do not have dosing guidelines for children younger than 12 years of age. Therefore, our results suggest that Xgly4 functions as positive regulator in non-canonical Wnt/PCP signaling during gastrulation. In many studies of self-care assessments for children, cultural differences in age-norm values have been shown. They must also discriminate among different food choices (i.e., bacteria), which is important because if the nematodes concentrate on an unsuitable food source, they may die. Evaluation of the effectiveness of HEVAC-B vaccine in a population at risk. MR findings of avulsive cortical irregularity of the distal femur. In an experiment to investigate cognitive skill differences between clinicians and lay persons, eight individuals in each group were asked to determine if an explicit concept existed in an ambulatory encounter note (a simple task) or if the concept could be inferred from the same note (a complex task).

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Effects of latrunculin B on outflow facility, intraocular pressure, corneal thickness, and miotic and accommodative responses to pilocarpine in monkeys. Pattern I is cerebral cortical injury, suggesting cortical laminar necrosis in hypoxic brain injury. Characterization of Leptospiraceae by 16S DNA restriction fragment length polymorphisms. Although the combination of a decision rule and D-dimer testing is safe in excluding UEDVT in the overall population of patients with suspected UEDVT, its efficiency appears limited in some subgroups, in particular those with a central venous catheter or pacemaker, and inpatients. These data are thus interpreted to indicate that a component of the transport system vertically penetrates one or both monolayer faces of the membrane during transport, or that some other event involving the lateral compression of the phospholipids is important for transport. Dehydration of untreated creatine monohydrate had a pronounced effect on the particle size of the powder. Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein.

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Extracts of several grain-based coffee-substitute blends and instant coffees were mutagenic in the Ames/Salmonella test using TA98, YG1024, and YG1029 with metabolic activation. Structure-activity relationships of these newly synthesised compounds were explored with respect to the significance of the position and number of nitrogen atom of the heteroaryl ring for anti-proliferative activity in human cancer cell lines. Incidence and visual analog scale scores of visceral pain and incidence of intraoperative nausea and vomiting were obtained from each patient. A number of processes are thought to contribute to the development of epilepsy including enduring increases in excitatory synaptic transmission, changes in GABAergic inhibition, neuronal cell death and the development of aberrant innervation patterns in part arising from reactive axonal growth. Fifty-three women with histologic evidence of uterine leiomyoma and 33 surgical controls without leiomyoma. Nuclear energy conversion is employed for radioisotope or nuclear reactor sensing. Conditioned cell medium from bronchial epithelial cells co-stimulated with hIL-17 plus TNF-alpha prolonged survival (trypan blue exclusion) of human neutrophils in vitro and this effect was blocked by an anti-GM-CSF antibody. The physiologically-based approach, with stochastic considerations, offers a powerful alternative to the empirical calculation of mean values. PCR detection in tear fluid is helpful in diagnosing this disease. In addition, the overall prevalence of screening positive for panic disorder in an ED is higher than previously reported.

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Intergrated television-system at the University Clinic Munich--Grosshadern. PPARgamma activation, by reducing oxidative stress, increases NO bioavailability in coronary arterioles of mice with Type 2 diabetes. Instead, a maximum increase of protein in the gel section of relatively slow anodal-moving globulins was observed. The most important clinical manifestation is chronic renal failure (CRF) or chronic renal disease (CKD) The management of CKD, apart from medical and nursing services, also involves a number of community structures and financial resources. Participants were recruited through advertisements and community-based referrals to a study investigating skeletal health in outpatients with anorexia nervosa. Cholangiohepatitis and pancreatitis secondary to severe gastroduodenal ulceration in a foal. However, the risk factors for mesenteric ischaemia are unclear and prognosis of patients after this type of ischaemic accident is not well defined.

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