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Alrif (Alprazolam)
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Alrif

Alrif is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alrif is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alrif may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Aldip, Alpanol, Alpose, Alpracon, Alpram, Alprasan, Alprine, Alprocalm, Alprogard, Alproz, Alsert, Alzin, Alzomax, Alzoset, Anilam, Anxyl, Anzilum, Avizolem, Calmef, Censir, Cqlam, Esteem, Flunix, Fluxin, Fultop, Notens, Pifzot, Poize, Prazolam, Rescalm, Richpram, Samitol, Sertamax, Setex, Somnia, Somnirest, Sowel, Suzilam, Synozolam, Tensyn, Xanti, Xylonite, Zolam, Zolark, Zolin, Zoloid, Zomark

Similar Products:
Lioresal, Requip, Sildigra, Moduretic, Asacol, Fosamax, Aceon, Levitra, Flonase

Also known as: Alprazolam

Description

{name} XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

{name} XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

{name} XR may also be used for other purposes not listed in this medication guide.

Dosage

Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alrif dosage information

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alrif XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alrif XR dosage information

Side effects

The most common side effects associated with Alrif are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Before taking Alrif, tell your doctor or pharmacist if you are allergic to it; or to other benzodiazepines (such as diazepam, lorazepam); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe lung/breathing problems (such as COPD, sleep apnea), liver disease, kidney disease, drug or alcohol abuse, glaucoma.This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Older adults may be more sensitive to the side effects of this drug, especially loss of coordination and drowsiness. These side effects can increase the risk of falling Alrif is not recommended for use during pregnancy due to the potential for harm to an unborn baby. Consult your doctor for more details.This drug passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

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Mutagenesis studies at a key surface residue (Thr-28) further support the important role played by these microheterogeneities for the assembly of the bipartite leucotoxins. When compared with bacterial populations developing under an ultraviolet-deficient condition, the heterotrophic populations from microecosystems exposed to an ultraviolet-supplemented sprectrum displayed an overall decrease in total numbers, an increase in the proportion of pigmented cells, a decrease in the number of cellulolytic microorganisms and an increase in heterotrophic respiration. A number of questions remain regarding the appropriate use, efficacy, and potential toxicity of iron therapy in dialysis patients. Myositis ossificans is a localized, self-limiting, reparative lesion that is composed of reactive hypercellular fibrous tissue and bone. More accurate staging is crucial to surgeons in customizing the operative procedure to the individual. Acetylated dendrimer only encapsulates Dp21 at acidic conditions, while cationic dendrimer can host Dp21 at both acidic and neutral conditions. On the physical properties of red cell ghost membranes in the affective disorders and psychoses. M-FISH with CRPs is thus not only useful in revealing a comprehensive picture of structural aberrations in target chromosomes, but also in narrowing down the minimal region for screening cancer-related genes. Encoding of tensile stress and strain during stretch by muscle mechano-nociceptors. Common patterns of irrational treatment of malaria were observed.

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CK activity, muscle volume and T(2) values were similar throughout the experimental protocol between the two groups. We investigated the role of SH2 domain containing protein tyrosine phosphatase (SHP) 2 in Concanavalin A (Con A) -dependent signaling that leads to the augmented secretion and activation of matrix metalloproteinase (MMP) 2. Glutaredoxins (GRXs) are small proteins which bind glutathione to either reduce disulfide bonds or to coordinate iron sulfur clusters. The purpose of this work is to provide a detailed account of a new technique for open prosthesis hernioplasty, a technique that makes use of a pre-shaped TramEC mesh made of polypropylene monofilament and created by the author. Has the dramatic growth in the NIH budget affected the training and production of biomedical Ph.D.s?. In this second article of a series of papers listing first case reports of animal diseases published since 2000, the following nine cases of cat diseases are discussed: Congenital spongiform change in the brain stem nuclei. However, the results obtained were noted in patients with the I-II stages of hepatic insufficiency.

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To synthesize the literature to determine the role of radiologic procedures in evaluating common causes of acute knee pain: fractures, meniscal or ligamentous injuries, osteoarthritis, and pseudogout. Complications following management of displaced intra-articular calcaneal fractures: a prospective randomized trial comparing open reduction internal fixation with nonoperative management. The effects of acute and chronic lithium treatment on rat submandibular salivation. PMA-induced increases in responsiveness were diminished by superoxide dismutase and catalase. The purified antibodies were dialyzed and used for the development of an ELISA incorporating HPA-1a-coated plates. Comparison of in vivo lymphocyte proliferation between allogeneic and xenogeneic heart transplantation in mice. This is relevant to us as surgeons because teamwork is now a common part of the vernacular in health care, we do not operate in a vacuum without a team, and we are well positioned to assume a leadership role on our teams.

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Variance in spatial distribution of the types of epidemic areas was observed. Molecular cloning of integrin-associated protein: an immunoglobulin family member with multiple membrane-spanning domains implicated in alpha v beta 3-dependent ligand binding. A case of synchronous hepatocellular carcinoma and aortic body chemodectoma in a dog - pathological case report. The differences between the recanalization potency of venous and arterial thrombi suggest that in addition to the organization of the fibrin meshwork, the cellular composition of the venous thrombi may be responsible for the better recanalization seen in venous clots. The Meta-analysis software, REVMAN4.1, was applied for investigating heterogeneity among individual studies and summarizing the effects across studies. The interaction between TAX4/IRS4 and INP51 is analogous to the association of EPS15 with the 5-phosphatase synaptojanin 1 in mammalian cells, suggesting that EPS15 is an activator of synaptojanin 1. This study was conducted to characterize the opiate dependence potential of a number of opiate and non-opiate psychoactive drugs in morphine-dependent cynomolgus monkeys (Macaca fascicularis). Based on the limited available evidence, this review suggests a benefit in terms of patient outcomes and reduction in the length of hospitalisation following midnight removal of the IUCs. GABA-immunoreactivity was present in all NPY-, in some of the SP- and 5HT-containing amacrine cells, but not in TH-immunoreactive amacrine cells. We undertook a pilot study to determine engraftment rates, kinetics of engraftment, toxicity, and acute graft-versus-host disease (GVHD) associated with a uniform reduced intensity haemopoietic stem-cell transplant (HSCT) regimen for children with non-malignant diseases.

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The availability of antiretroviral therapy has significantly reduced the morbidity and mortality of HIV infection. The method was evaluated in DWI scans of adult volunteers who deliberately moved during scans as well as clinical DWI of 28 neonates and children with different types of motion. Arrhenoblastoma associated with adrenal androgenic hyperfunction. Furthermore, according to the geometric interpretation of SVDD, a method of computing the sphere radius is proposed when the optimal solution with respect to the sphere radius in the primal optimization problem is non-unique. Here we report the first results from a large prospective cohort study of pigmentation factors and sun exposure in relation to melanoma risk. Buried scour chains (100 at each of three 20-m sites within a 350-m reach) indicated that a spate with a return period of 5 months caused a mosaic of bed patches with different stabilities. 2) To relate the occurrence of the various types of CNS tumors to age, sex, symptoms, neurologic findings and location.

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When this V1 activity was present, it marked the beginning of a weak wave of excitations in striate and extrastriate areas which ended at 50 ms (M50). The heterogeneous nature of the topic, combinations of interventions implemented and methodological weaknesses of the studies impairs the ability to aggregate data and develop specific recommendations for practice. Although both gangrenous and convulsive symptoms are seen in naturally occurring ergotism resulting from the ingestion of fungus infected rye, only gangrenous ergotism has been reported following the excessive ingestion of ergotamine tartrate. Treatment of AAA with Ella stent-graft system is effective and safe. Effect of glucosamine administration in normal rats in comparison with streptozotocin treatment. Additionally, Gd-DOTA dynamic contrast-enhanced (DCE) MRI was performed to estimate transfer constants (Ktrans) and volume fractions of the extravascular extracellular space (ve) using standard Tofts-Kermode tracer kinetic modeling. Most enzymes and/or proteins are commonly stored in glycerol to maintain their activity/function. We propose and numerically demonstrate a secure key distribution scheme based on the dynamic chaos synchronization of two external cavity vertical-cavity surface-emitting lasers (VCSELs) subject to symmetric random-polarization injections. The apparent first-order rate constants for the photodegradation of RF and for the formation of LC and CDRF at 0.25-2.00 M phosphate concentration range from 0.65 to 3.03 x 10(-2), and from 0.41 to 0.99 x 10(-2) and 0.12 to 1.63 x 10(-2) min(-1), respectively. Cross-neutralization tests showed that these viruses were distinct from all known human enterovirus immunotypes, but that they were antigenically closely related.

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The in vitro change in the microchimeric cell population size was measured following immunologic stimuli, which were expected to trigger antigen-specific T cells. We investigated the molecular mechanism by which androgen-sensitive C-33 LNCaP human prostate cancer cells become NE-like cells in an androgen-reduced environment, mimicking clinical phenomenon. In a retrospective study of the ultrastructural findings of 24 gastrointestinal stromal tumours, whose light microscopic study has yielded ambiguous results and in which accurate diagnosis had required ultrastructural support, seven were found to have the characteristics of gastrointestinal autonomic nerve (GAN) tumours. Beneficial effect of interferon alfa-2b appears to be associated with a down-regulation of adhesion molecules on hepatocytes, suggesting that this novel immunomodulatory action of interferon could be important to induce a therapeutic response in viral chronic hepatitis. However, we also found a significant frequency of intellectual impairment and argue that this factor may have been overlooked in the history of filicide investigations. This study aimed to highlight the clinical features of patients with soft tissue sarcomas with intra-tumour haematoma. The localisation and reduction of nuclear staining of PPARgamma and PGC-1 in human breast cancer.

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Mapping of a substrate binding site in the protein disulfide isomerase-related chaperone wind based on protein function is motrin an anti inflammatory medication and crystal structure. Post-embolic pulmonary arteriosclerosis and pulmonary hypertension in rabbits receiving an intravenous infusion of allogeneic bone marrow. Low human immunodeficiency virus type 1 (HIV-1) DNA burden as a major cause for failure to detect HIV-1 DNA in clinical specimens by PCR. Golgin-84 is a membrane-anchored golgin that we now show binds preferentially to the GTP form of the rab1 GTPase. Erythrocytes in normal conditions have weak interactions with other blood cells and endothelial cells while in pathological circumstances they can adhere to endothelium and aggregate or agglutinate to blood cells. There were no other episodes of SVT after discontinuing usage of fenoterol inhalation for 2 years in the follow-up. Here we show that multiple cis-acting sequences present on the chromosome can mediate transfer of a non-mobilizable test plasmid.

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Comparison of the PGE1 and catecholamines influence on the active transport of sodium. We found that mesenchymal stem cells (MSCs), the precursors of different mesenchymal tissues with a role in processes in which HB-EGF is often involved, normally express HER-1, but not HB-EGF itself. It is not suitable for comparison of interdisciplinary journals. Ninety-seven indications were rated as appropriate, 34 were rated as uncertain, and 71 were rated as inappropriate. Whether MetS and its components are also predictive of CVEs in chronic hemodialysis (HD) patients remains unclear. Expression of the identified gene was examined by RT-PCR and real time quantitative PCR (TaqMan-PCR) using 26 pairs of human prostate cancer and normal tissues. To investigate the prognostic effect of microRNA single nucleotide polymorphisms (SNP) on non-small cell lung cancer (NSCLC) patients, 658 female participants from northeast China were enrolled in our prospective cohort study and followed up from 2010 to 2015.

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At 40 days of gestation, prior to the appearance of follicle primordia, bFGF immunoreactivity was detected in the intermediate and periderm layers of the epidermis and at the dermal-epidermal junction. It turns out that the structure of the weight matrix of the network represents the structure of the set of patterns it is acting on, not the patterns themselves. Trunk extension effort in patients with chronic tenormin 50 mg side effects low back dysfunction. EMS was involved in the majority of out-of-hospital heart disease death events, resulting in a measurable reduction in heart disease mortality. Our results strongly suggest that CRP is associated with CAD, independent from conventional risk factors, and that inflammatory mechanisms may play a role in its pathogenesis.

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In deciding whether to obtain lumbosacral spine films, the emergency physician must not ask whether a diagnosis can be established, but whether obtaining films will affect management. Water-rock interaction and geochemistry of groundwater from the Ain Azel aquifer, Algeria. Few studies pamelor antidepressant reviews have examined these factors among children presenting for care at pediatric sleep clinics. Hitherto unknown pentaalkynylpyridines have been prepared in high yields by Sonogashira cross-coupling reactions of pentachloropyridine. In groups receiving myoblast transplantation, either by way of gel suspension or in the form of undifferentiated or differentiated constructs, muscle quality was superior to controls. Corneal Lenticule Allotransplantation After Femtosecond Laser Small Incision Lenticule Extraction in Rabbits. Bladder cancer: Assessing the conundrum of microscopic haematuria. According to the reported results, an Achilles tendon allograft should be considered the gold standard repair.

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