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Anabrez (Anastrozole)
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Anabrez

Anabrez is one of the first choice options for breast cancer that helps improve survival rates, but it is used only in women who've already reached menopause. It can cause hot flashes, night sweats, and headaches.

Other names for this medication:
Altraz, Altrol, Anabrez, Anastrocare, Anastrozole, Anatero, Anazol, Armilon, Armotraz, Femistra, Femitraz, Qubol, Redest, Rimidex, Stazonex, Xenosoul

Similar Products:
Arava, Revia, Plaquenil, Periactin, Decadron, Colcrys, Loxitane

Also known as: Anastrozole

Description

Generic Anabrez is brand name for anastrozole, an oral antiestrogen. Generic Anabrez inhibits the enzyme aromatase in the adrenal glands that produces the estrogens (estradiol and estrone) and thereby lowers their levels. Generic name of Generic Anabrez is Anastrozole. Anabrez is also known as Anastrozole. Brand name of Generic Anabrez is Anabrez.

Dosage

The following information describes Anabrez dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Drug forms and strengths

Anabrez comes as 1-mg tablets that are taken by mouth.

Dosage for breast cancer

The usual dosage of Anabrez for breast cancer is one tablet taken once a day. It’s best to take your dose at the same time each day.

What if I miss a dose?

If you forget to take a dose of Anabrez, take the missed dose as soon as you remember. However, if it’s almost time for your next dose, just skip the missed dose and take your next dose as usual. Don’t take two doses together to make up for a missed dose.

To help make sure that you don’t miss a dose, try setting a reminder on your phone. A medication timer may be useful, too.

Will I need to use this drug long term?

Anabrez is meant to be used as a long-term treatment for breast cancer. If you and your doctor determine that Anabrez is safe and effective for you, you’ll likely take it long term.

The length of time that you’ll take this drug depends on the type of cancer you’re using it to treat. Below we describe the typical length of time that Anabrez is given. But to know for sure how long you should take Anabrez, talk with your doctor.

For advanced breast cancer

If you’re taking Anabrez to treat advanced breast cancer, you’ll usually take the drug for as long as your doctor feels this treatment is right for you. (With advanced breast cancer, the cancer has either spread to nearby areas or lymph nodes, called locally advanced breast cancer, or spread to other parts of your body, called metastatic breast cancer.)

For early breast cancer

If you’re taking Anabrez as adjuvant treatment of early breast cancer, you’ll usually take the drug for at least 5 years. Adjuvant treatment is used to lower the risk of your breast cancer coming back or spreading after it’s already been treated with surgery. (With early breast cancer, the cancer hasn’t spread out of either your breast or the lymph nodes in your armpit.)

It’s not currently known if Anabrez should be continued after these 5 years. And if so, it’s not known for how long after the first 5 years it should be taken.

Some studies found that breast cancer is less likely to come back if an aromatase inhibitor is taken for an additional 5 years after the first 5 years of adjuvant therapy. (Aromatase inhibitors are a class of medications.) With this approach to treatment, the drug would be taken for a total of 10 years. However, other studies didn’t show a benefit for extending the treatment beyond 5 the usual years.

In addition, one recent study found that taking Anabrez for a total of 10 years didn’t provide any more benefit than taking it for a total of 7 years.

How long you take Anabrez for early breast cancer will depend on how likely your breast cancer is to come back. It will also depend on your risk of side effects from treatment.

Overdose

If you overdose Generic Anabrez and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Anabrez are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Anabrez if you are allergic to anastrozole, or if you have not yet completed menopause.

Anabrez is not approved for use in men or children.

You should not take anastrozole if you also take tamoxifen.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

heart problems; coronary artery disease (clogged artery disease); high cholesterol; or osteoporosis or low bone mineral density.

Hormonal cancer treatment can weaken your bones. You may be more likely to have a broken bone while using Anabrez. Talk with your doctor about ways to keep your bones healthy.

Although it is not likely that a postmenopausal woman would be pregnant, anastrozole may harm an unborn baby. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control if you are not past menopause. Keep using birth control for at least 3 weeks after your last dose of Anabrez. Tell your doctor if you become pregnant.

Do not breastfeed while using this medicine, and for at least 2 weeks after your last dose.

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In stroma, the protein expression of SHBG was lower in PCOSEs than in CEs. To identify common cis-regulatory elements in co-regulated genes, a resulting gene list can directly be exported to the AthaMap database for analysis. HPV vaccination decision-making is a complex process that is influenced by multiple psychosocial determinants. A 3 x 2-factorial balance trial was conducted with dietary concentrations of P below the requirement (3.6, 4.3 and 5.0 g/kg DM) and Ca below or at the requirement (28 and 37 g/kg DM) adjusted by monobasic calcium phosphate (MCP, Ca(H2PO4)2) and calcium carbonate (CaCO3). They want to be assured that participation will not cause them harm and that the research is conducted with good intentions. Linkage of VH-Xmp to IgCH allotype locus and mapping with respect to other known VH genes. Clozapine-induced agranulocytosis: Evidence for an immune-mediated mechanism from a patient-specific in-vitro approach. Patient satisfaction has only recently gained attention as an outcome measure in orthopaedics, where it has been reported for joint replacement surgery.

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Three-dimensional conformal radiotherapy versus intracavitary brachytherapy for salvage treatment of locally persistent nasopharyngeal carcinoma. Arthroscopic coracoid decompression was performed, and bactrim antibiotic treats what intraarticular pathology was documented. Effect of adrenocorticotropic hormones on lability of plasma and serum proteins in allergic diseases. This rare entity was identified by video-mediastinoscopy, which revealed a granulomatous and fibrosed recurrent lymph node encasing the nerve. In this review, we have focused on the association of lncRNAs in the development and progression of OA and the possibility of lncRNAs as a therapeutic agent for the treatment of OA. There is much more to organizational culture than the diversity issue. This study uses a nationwide population-based dataset to explore factors and patterns associated with traditional Chinese medicine (TCM) usage among schizophrenia patients. The present study was undertaken to evaluate the short-term effects of nitroglycerin, nifedipine, and supplemental oxygen on hemodynamics and gas exchange in 11 patients in stable condition with chronic obstructive pulmonary disease and cor pulmonale. Regulation of gene expression in Streptococcus pneumoniae by response regulator 09 is strain dependent.

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An experimental study of the regeneration of mammalian striped muscle. At the palm, FTSG offers better mechanical resistance then a split-thickness skin graft. Therefore, in an effort to identify TRPA1 antagonists, the authors used large-scale transiently what happens if you take panadol and drink alcohol transfected (LSTT) cells, enabling rapid establishment of assays suitable for HTS. For torsion tests, 1 side of the screw was fixed and other was twisted clockwise. Third-party payor conflicts of interest in managed care: a proposal for regulation based on the model rules of professional conduct. To evaluate the usefulness of Optical Coherence Tomography (OCT) images for surgical indication, intraoperative management and postoperative outcome of patients with idiopathic epiretinal macular membrane (IEMM). These results suggest that this immunization regimen could not completely protect the monkeys from SIV infection but that it did reduce the replicability of the challenged virus. Transfection of the mutant MYH9 cDNA reproduces the most typical cellular phenotype of MYH9-related disease in different cell lines. Cytoplasm to vacuole trafficking of aminopeptidase I requires a t-SNARE-Sec1p complex composed of Tlg2p and Vps45p.

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Keeping pace with new technologies: systems needed to identify and evaluate them. The system includes a laser-induced fluorescence microfluidic chip analyzer, a glass microchip for both polymerase chain reaction (PCR) and capillary electrophoresis, a chip thermal cycler based on dual Peltier thermoelectric elements, a reverse transcription-polymerase chain reaction (RT-PCR) SARS diagnostic kit, and a DNA electrophoretic sizing kit. The aim of this paper is to describe the NCDU program introduced by the Centre for Psychiatric Nursing Research and Practice (CPNRP) in Melbourne, Victoria. Study of renal function by means of the isotope renogram in patients with neurogenic bladder caused by spinal cord lesions. A case of distal type of renal tubular acidosis associated with chrysotherapy. These results support the conclusion that lobGRK2 responds to odorants and to neurotransmitters and may act to initiate desensitization by phosphorylating G-protein-coupled receptors in the olfactory organ and the brain, respectively. It is shown, that the covalent cross-link of D-dimer gamma-gamma-chains affects the inhibitory features and mechanism of interaction with fibrin monomer molecules. Efficacy outcomes were considered as the change from baseline in best corrected visual acuity (BCVA) and central macular thickness (CMT).

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Validation using 43 reference isolates from different animal species revealed good performance characteristics regarding sensitivity and specificity. Men reporting a greater psychological impact of erectile dysfunction also reported greater impairment in functional status, lower sexual self-efficacy, greater depression and anxiety at the last intercourse. Application of a marker of ciliated epithelial cells to gynaecological pathology. Except for (CAG)27, and (CAG)40, 293T cells showed a common set of morphological alterations such as shrinkage, rounding and surface blebbing when the expanded stretch was expressed. Magnetic resonance imaging and immunohistochemistry of primary vertebral hemangiosarcoma in a dog and implications for diagnosis and therapy. Histological examination showed heterotopic ossification in the tumor. The authors also observed that maxillary bone thickness increased toward the upper areas of the lacrimal sac fossa and with increasing subject age. Furthermore, the quality of the shallow and deep aquifer (using tube well and hand pumps) was also investigated for their best ecological use including drinking, domestic, agricultural and other activities.

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