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Anazac (Tramadol)

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Anazac is a centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults. Anazac is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine.

Other names for this medication:
Bramadol, Contramal, Doleira, Dolstar, Domaspas, Esgiypyrin, Gemodol, Moludol, Nobligan, Nomadol, Opiran, Pacadon, Painex, Ramadol, Ramax, Redimol, Relidol, Servodol, Tramadol, Tramak, Tramakind, Tranat, Trapain, Ubitdol, Zytram

Similar Products:
Glucophage, Zovirax, Lamisil, Lioresal, Minocin, Provera, Nexium

Also known as: Tramadol


{name} (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

{name} is used to treat moderate to severe pain in adults.

The extended-release form of tramadol ({name} ER) is for around-the-clock treatment of pain. {name} ER is not for use on an as-needed basis for pain.


Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Anazac: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Anazac is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Anazac dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Anazac are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Anazac ER if you are allergic to it, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Anazac ER should not be given to a child younger than 12 years old. Anazac ER should not be given to anyone younger than 18 years old.

Do not give Anazac ER to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Anazac ER. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

Tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use Anazac ER during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using Anazac ER if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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Temporal photoreception for adaptive dynamic range image sensing and encoding. A counterintuitive decrease in the mean aggregate size was apparent in the lower flow rate branches. The posttest results revealed that the children who received the intervention knew significantly more about several drugs than a matched comparison group. An emergency decompressive craniotomy was carried out to remove the hematoma. The incidence of cases of misdiagnosis and inappropriate discharge of patients resulting in a delay in diagnosis and treatment was also assessed.

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By exploring several expression systems and designing a number of constructs, we were able to purify the enzyme in its active form and we found that it is tightly bound to the membrane through the N-terminal residues. To evaluate the effectiveness of a new site-specific, manual soft-tissue therapy in increasing orgasm and reducing dyspareunia (painful intercourse) in women with histories indicating abdominopelvic adhesion formation. Furthermore, we demonstrate that KAP-1 but not TIF1alpha interacts with the KRAB multifinger ZNF74 in the nuclear matrix. Patients were divided into two groups: one group of patients recognized as having an occupational disease and a group of patients whose disease was not considered occupation-related. O-TRENSOX exhibits a high and selective affinity for Fe(III) complexation. The Latino and his culture: Chronicle of a death foretold by Gabriel Garcia Marquez. PA, CRP and AGP measurements are superior to PINI for assessing postoperative metabolic changes in term neonates following uncomplicated major surgery on early and late phase. The strong potential of cannabinoids for inducing long-term alterations in hippocampal neurons through the activation of the ERK pathway may be important for the physiological control of synaptic plasticity and for the general effects of THC in the context of drug abuse. Detection of Alzheimer type pathological epitopes on Tau proteins of neuroblastoma cells after treatment with okadaic acid. Here, we investigate the role of primary cilia in EFS-enhanced osteogenic response of human adipose-derived stem cells (hASCs) by knocking down 2 primary cilia structural proteins, polycystin-1 and intraflagellar protein-88.

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The Dutch Bypass and Oral anticoagulants or Aspirin (BOA) Study demonstrated that in patients with peripheral arterial disease after bypass surgery oral anticoagulants were more effective in preventing venous graft occlusions than aspirin, while aspirin was selegiline dose more effective in non-venous grafts. Specific potassium binding stabilizes pI258 arsenate reductase from Staphylococcus aureus. Comorbid conditions, including risk factors and components of the Charlson comorbidity index (ChCI) and coronary artery disease-specific index, were recorded. Disturbances of the rapid eye movements (REMs) of REM sleep in patients with unilateral attentional neglect: clue for the understanding of the functional meaning of REMs. Bivariate random-effects meta-analytical methods were used to estimate summary and subgroup-specific sensitivity, specificity, and receiver operating characteristic curves and to investigate the effects of study design characteristics and imaging procedure elements on diagnostic accuracy. Suppression of radiation-induced point defects by rhenium and osmium interstitials in tungsten. The interrelationship of the thyroid and immune statuses of workers with long-term fluorine exposure. Further research into the experiences of consultant nurses is necessary - in particular, how nurse consultants interpret their relationships with others, negotiate resources and demonstrate the impact of their role in each of the core functions, notably the leadership function.

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How to treat infected permanent cardiac pacemakers and retained endocardial electrodes. The method is adapted to the use of multi-channel action recorders, thus allowing a greater number of sensor units to be employed simultaneously.As an example of application, a comparison is made between the diurnal rhythmicity patterns of locomotor activity inDrosophila melanogaster andDrosophila azteca. Arterial chemoreceptors in the superior laryngeal nerve of the rat. MitraClip (MC) is an alternative treatment for mitral regurgitation (MR). According to data obtained in adults, functional genetic polymorphisms influence cytokine production capacity.

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Educational achievements, employment and social class of insulin-dependent diabetics: a survey of a young adult clinic in Liverpool. That was interpreted as a mathematical support of the law of step-by-step development of the disease. Twelve patients underwent hydrogalvanic baths, 13 patients the Jacobson relaxation training. Human exposure assessment in the near field of GSM base-station antennas using a hybrid finite element/method of diabetic medicine glimepiride moments technique. However, challenges of comprehensive therapeutic outcome evaluations in schizophrenia can also be potentially overcome using CDT. These studies demonstrate that naMuIFN-gamma binds in a specific manner and with high affinity to murine cell receptors. The role of ACTH in the regulation of cholesterol metabolism in the adrenal cortex. Regulation and mechanism of phosphoribosylpyrophosphate synthetase. We here review the indication for iEEG for the work-up of patients suffering from pharmacoresistant epilepsy. Encapsulated sumatriptan is not bioequivalent to commercial sumatriptan.

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