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Angibloc (Losartan)

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Angibloc belongs to a group of drugs called angiotensin II receptor antagonists (sometimes called ARB blockers). It keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. Angibloc is used to treat high blood pressure (hypertension) in adults and children who are at least 6 years old. It is also used to lower the risk of stroke in certain people with heart disease.

Other names for this medication:
Arapres, Cardzaar, Fensartan, Forzaar, Insaar, Klosartan, Lepitrin, Logika, Loortan, Loplac, Losacor, Losamet, Losaprex, Losarb, Losart, Losartan, Losartax, Losartil, Losatan, Lotan, Lotim, Lozap, Lozatan, Lozitan, Ocsaar, Psycholanz, Repace, Rosatan, Stadazar, Tacicul, Tanlozid, Temisartan, Tensartan, Tensiohess, Tozaar

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Also known as: Losartan


{name} (losartan) belongs to a group of drugs called angiotensin II receptor antagonists (sometimes called ARB blockers). It keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

{name} is used to treat high blood pressure (hypertension) in adults and children who are at least 6 years old. It is also used to lower the risk of stroke in certain people with heart disease.

{name} is also used to slow long-term kidney damage in people with type 2 diabetes who also have high blood pressure.


Usual Adult Dose for Diabetic Nephropathy:

Initial dose: 50 mg orally once a day Maximum dose: 100 mg orally once a day Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. -Antihypertension is substantially present within 1 week but in some studies the maximal effect occurred in 3 to 6 weeks. Uses: -Treatment of hypertension. -To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. -Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension.

Usual Adult Dose for Hypertension:

Initial dose: 50 mg orally once a day Maximum dose: 100 mg orally once a day Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. -Antihypertension is substantially present within 1 week but in some studies the maximal effect occurred in 3 to 6 weeks. Uses: -Treatment of hypertension. -To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. -Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension.

Usual Pediatric Dose for Hypertension:

6 Years or Older: Initial dose: 0.7 mg/kg orally once a day (up to 50 mg total) Comments: -May be given as a tablet or suspension. -Doses above 1.4 mg/kg (or 100 mg) daily have not been studied in pediatric patients.

Detailed Angibloc dosage information


If you overdose Angibloc and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Angibloc overdosage: fainting, feeling lightheaded, rapid heartbeat.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Angibloc are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Use of drugs that act on the renin-angiotensin system during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. Resulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformations. Potential neonatal adverse effects include skull hypoplasia, anuria, hypotension, renal failure, and death. When pregnancy is detected, discontinue Angibloc as soon as possible.

In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with Angibloc. Correct volume or salt depletion prior to administration of Angibloc.

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The history, technique and clinical role of percutaneous PFO and VSD closure are discussed, with emphasis on current problems and future developments. Carbon monoxide (CO) has long been known to have dramatic physiological effects on organisms ranging from bacteria to humans, but recently there have a number of suggestions that organisms might have specific sensors for CO. Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion. Detection of casein fragments in an invertebrate and in a vertebrate using in situ hybridization. Guided bone regeneration using osteopatite granules and polytetrafluoroethylene membranes. A total of 632 paired samples were tested for IgG antibody for the following (number of seroconversions in parentheses): Rickettsia (spotted fever and typhus groups) (25), West Nile fever virus (WNV) (23), Coxiella burnetii (causative agent of Q fever) (12), dengue virus (8), leptospirosis (6), chikungunya virus (0), Congo-Crimean hemorrhagic fever virus (0), Japanese encephalitis virus (0), and Rift Valley fever virus (0).

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No thymine could be recovered from a similar extract of 5,000 times as many sperm of the same species. This study was a retrospective, single-institution review of RBC transfusions in VLBW infants. The influence of these changes and their applicability within the requirements and the criteria for mass spectrometry set by the responsible regulatory bodies are discussed. Less than 160 cases of intrapericardial or intracardiac paragangliomas have been reported in the English language peer-reviewed medical literature. The endosymbiotic theory for the origin of eukaryotic cells proposes that genetic information can be transferred from mitochondria to the nucleus of a cell, and genes that are probably of mitochondrial origin have been found in nuclear chromosomes. This prospective cohort included 50 subfertile couples undergoing IVF in western Massachusetts. Site-specific glycosylation of the Newcastle disease virus haemagglutinin-neuraminidase.

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Laccase-catalyzed oligomerization of proteins was studied using Trametes hirsuta laccase (ThL) and coactosin as a model system. The aim of this study was to establish the actual prevalence of ocular hypertonia and crystalline lens opacities in a group of healthcare workers exposed to ionising radiation. Results of this evaluation suggested that the programme was able to provide a positive clinical experience in mental health for nursing students and is worthy of a more controlled investigation. The neuropsychological and psychosocial functioning of infant heart transplant recipients will be important to address as they mature during adolescence and adulthood. The data obtained suggest a modulating role of amino acids in the tissues at different stages of maturation. Aortic stiffness was assessed by measuring carotid-femoral pulse wave velocity (PWV). To analyse the expression of multidrug resistance (MDR) related proteins at different steps in colorectal carcinogenesis. These reduced levels of bacterial adherence on the coated surface were still evident after treatment with saliva. Grain density was greater in the peripheral regions of the ampullar crista compared to the vertex.

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A study on the clinical effects of physical therapy and acupuncture to treat spontaneous frozen shoulder. The global rigid rotor four-dimensional potential energy surface is obtained by fitting ab initio points with a least squares procedure for the angular terms and interpolating the radial coefficients with cubic splines. In breast conservation, prophylactic axillary dissection seems to be omitted, but the axilla of the affected side should be examined for metastasis while treatment is possible. We developed a humanized anti-CD70 antibody, SGN-70, and herein describe the antitumor activities of this mAb. ICD-9 to AIS mapped scores have worse discrimination than their AIS-based counterparts, but still show moderate performance. Role of hypocapnic alkalosis in hyperventilation-induced coronary artery spasm in variant angina. The type of progestin and the ratio of EE to progestin used in oral contraceptive pills (OCPs) may determine how they affect the arterial vasculature. Significant cultural differences were found for the total anxiety scale and three of the four subscales. Helicobacter pylori multiplex PCR and RT-PCR assays were carried out using primer pairs targeting the cagA, vacA, ureA, ureI, hspA (hsp60), and sodB genes and their cDNA. In conclusion, pharmacokinetic and biodistribution studies of (177)Lu-7E11 in LNCaP xenograft mouse models support its potential application as a radioimmunotherapeutic agent targeting prostate cancer, and the distribution and tumor uptake of (111)In-7E11 appear to be similar to those of (177)Lu-7E11, supporting its use as a pre-therapeutic tool to assess the potential accumulation of (177)Lu-7E11 radioimmunotherapeutic at sites of prostate cancer.

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All clinic patients of reproductive age, presenting with cyclical behavioral changes in our clinic from November 1985 to October 1992. Paper screening and citation snowballing left 77 included papers. The data presented herein suggest that the anti-apoptotic function of ST may explain, at least in part, how ST contributes to SV40 early region induced transformation of REF cells. 4 It is suggested that free radical formation by anthralin has a direct action on membrane substrates such as arachidonic acid forming inflammatory products by a non-enzymic process. Topical beta-carotene penetrated well into human and mouse epidermis and induced a 10-fold (human) and a threefold (mouse) increase of epidermal retinyl esters, which demonstrates that topical beta-carotene is converted into retinyl esters by human and mouse epidermis and thus appears as a precursor of epidermal vitamin A. To analyze the changes of the main clinic parameters in patients with benign prostate hyperplasia (BPH) treated by watchful waiting and to find out the risk factors contributing the progress of BPH. To investigate the role of BACE1 in ST6Gal I secretion in vivo, we analyzed the levels of BACE1 mRNA in the liver, as well as the plasma levels of ST6Gal I, in a hepatopathological model, i.e. TBIs were not medically confirmed and anxiety and depression were only assessed every four years by self-report, rather than clinical interview. High-Affinity DNA Aptamer Generation Targeting von Willebrand Factor A1-Domain by Genetic Alphabet Expansion for Systematic Evolution of Ligands by Exponential Enrichment Using Two Types of Libraries Composed of Five Different Bases. There was no significant difference in latency of the dinner request or the energy intake at dinner between sessions.

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We performed a retrospective review of children treated from birth for cloacal exstrophy between March 1, 1994 and January 1, 2003 at our institution. Arrestin was also recruited to the plasma membrane and appeared to colocalize with internalized receptors in response to SDF but not PMA. In practice stable diffusive demixing can only be achieved when special precautions are taken in experiments on real mixtures. This study, which was conducted in Cyprus, combines the theoretical framework of attribution research with that of parent involvement literature. Young Nile crocodiles Crocodylus niloticus start to produce calls inside the egg and carry on emitting sounds after hatching. These parameters are trained to their optimum status during the learning stage.

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Healthcare information system architecture (HISA) and its middleware models. We highlight microfluidic diagnostic systems which demonstrate practical integration of sample preparation, analyte enrichment, and optical detection. Fall injuries represent a huge healthcare, social and financial burden to the Canadian population. Repeated constrictions, which are asynchronous between neighbouring cells, are interrupted by pauses in which the constricted state of the cell apex is maintained. We also examine the value of the method in detecting restenosis. We also provide preliminary evidence that a complex motor task for the non-dominant hand is a useful probe of putamen function in this disorder.

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Placement was possible for only seven of the 30 or so described fossil species of Nothofagus because only these had sufficiently good preservation of both cuticular and leaf architectural characters. The process undertaken in the clinical nurse specialist task force is also described, including the key issues that emerged and lessons that were learned. Role of iron ions in the production of hemolysin by toxigenic and nontoxigenic Vibrio cholerae of different serogroups. Radiation-induced apoptosis was efficiently counteracted by growth factors up to 24-48 h after 3 Gy HDR exposure. Metformin, which remains the only biguanide hypoglycaemic agent currently prescribed in France, may also lead to this complication. Three neonates were admitted with purulent conjunctivitis, and an initial diagnosis of gonococcal ophthalmia was made because gram-negative diplococci were seen on gram stains of conjunctival exudates. Acute transfusion reactions in the pediatric intensive care unit. Supplementation with Brazil nuts and green tea extract regulates targeted biomarkers related to colorectal cancer risk in humans. The study used a combination of interview and postal questionnaires to SLTs, with particular emphasis on the issues that may affect service provision.

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P-nitrophenyl palmitate (p-NPP) was identified as the best substrate of PWTSB and PWTSC. Corneal endothelial touch can be prevented by the use of Healon, which is sufficient if short-term gas tamponade is used. Microscopic evaluation was carried out using morphometric computer system MicroImage InCD UDF (Olympus). These studies demonstrate that evolutionarily distant organisms utilize conserved factors to regulate early germ cell development and survival, and that these factors include members of the nanos and pumilio gene families. Quantification is challenging, but of particular interest in cancer research as targeting arginine and methionine turnover in cancer cells represent novel treatment strategies. In this redescription, we amend the original description by noting that there are only four cephalic papillae and that there are five pairs of post-anal papillae, and propose that the name of this species be corrected from S. Obligatory role for phosphatidylinositol 4,5-bisphosphate in activation of native TRPC1 store-operated channels in vascular myocytes.

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By using bioinformatics and rapid amplification of cDNA ends (RACE), we found a novel HCC-associated gene IDD01. These conditions are not expected to occur as a result of normal environmental exposure. Together, these findings indicate that a well controlled exercise program can be recommended for patients with DM and PM. A retrospective study of 73 transplantations over a period of 28 years. The interrelationship and possible causality of polyamine synthesis and the transmethylation pathway in the growth-retarding effects of inadequate or excess dietary methionine was studied in young male rats. Differential effects of Bifidobacterium pseudolongum strain Patronus and metronidazole in the rat gut. Thoracoscopy has provided chest physicians and surgeons with an opportunity to rethink their approach to patients with pleural and pulmonary disease. The residual deficits between the normal and the microphthalmic sides were expressed in percentages.

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Nuclear runon analysis showed that this increase was attributable to increased MCP-1 gene transcription. Risk of permanent medical impairment (RPMI) in road traffic accidents. Dynamic association of CD45 with detergent-insoluble microdomains in T lymphocytes. Here we show that separase is excluded from cohesin by the generic name compazine nuclear envelope, which forms in telophase and disassembles in mitosis. Nonzero temperature is shown not to be a limitation to obtaining high visibility fringes. Compared to control littermates, raptor(ad-/-) mice had substantially less adipose tissue, were protected against diet-induced obesity and hypercholesterolemia, and exhibited improved insulin sensitivity. Cloning of mpd gene from a chlorpyrifos-degrading bacterium and use of this strain in bioremediation of contaminated soil. The object of this study was to assess the effect of a graded dietary vitamin E (E) intake on E concentration in specific regions of the brain, and its influence on vitamin C levels and neurological function.

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The intra- and interobserver variability of the digitizer evaluation of cosmesis was smaller than that of the panel evaluation. There is little contemporary information on the clinical progression, need for mechanical circulatory support, and outcomes of orthotopic heart transplantation of these patients. After antibody infusion the anaesthesia time was more than doubled but the responses to CG 3509 were increased, suggesting a role for endogenous TRH in arousal mechanisms which is sensitized following chronic immunological blockade. Data from experimental models of glomerulonephritis, especially of lupus nephritis, have demonstrated that mycophenolate mofetil reverses both inflammatory and autoimmune aspects of disease and influences outcome. However, the mechanism of action of the sling is not intuitively clear. Nurses need to increase their knowledge base about CAMs in order to help patients in decision making regarding the use of these agents to treat common psychiatric symptoms.

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In addition, a Tat-based vaccine elicits an immune response capable of controlling primary infection of monkeys with the pathogenic SHIV89.6P at its early stages allowing the containment of virus spread. Both drugs produced a significant reduction in intraocular pressure (p less than 0.01). Grain should be harvested at lowest possible humidity, or immediately dried to safe storage humidity to prevent the growth of fungi. In this study, protein secretions of the ascomycete Metarhizium anisopliae, which conferred bioinsecticidal activity against Callosobruchus maculatus, were characterized via 2D electrophoresis and mass spectrometry. Recognition of RANTES by extracellular parts of the CCR5 receptor. Two patients with Stage IIIC OC were matched for each Stage IVB EC based on age and residual disease. Cell proliferation was quantified by means of the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, ROS was determined using the nitro blue tetrazolium test, apoptosis was morphologically determined using Hoechst 3332 and APh activity was assayed spectrophotometrically. We undertook this retrospective study to identify risk factors of operative mortality in dialysis patients who underwent CABG.

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The Src homology phosphotyrosyl phosphatase, SHP2, is a positive effector of EGFR signaling. Plasmalogens in the retina: in situ hybridization of dihydroxyacetone phosphate acyltransferase (DHAP-AT)--the first enzyme involved in their biosynthesis--and comparative study of retinal and retinal pigment epithelial lipid composition. Our methodology selectively revealed the details of associations between specific carotenoid molecules and specific protein binding sites. April 1999--44 year old man with a bleeding intracerebral tumor. Few pediatric series have been published, with retrospective and short-term follow-up studies. Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells. EBV positivity was more prevalent in male patients (4/6), and the tumor tissues depakote medication monitoring of the 4 EBV-positive cases were featured by obvious stromal infiltration by the lymphocytes (4/6). Movement is fundamental to human well-being, function and participation in work and leisure activities. Serum cystatin C (Scyst) has an obvious advantage in recognizing the initial stages of renal impairment. Data were analyzed with multiple regression, which controlled for age, sex, and IQ.

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The recent introduction of atypical antipsychotics seems to reduce the risk of TD in patients with long-term and maintenance therapies. Clinical, electrocardiographic, radiographic, hemodynamic, and angiographic findings in six cases. Clinical observations are presented on the sensory effects of lesions of different afferent pathways of the spinal cord, correlated whenever possible with histological evidence of the location and extent of the lesions. Here, the body of work linking Sirtuins with ALS is reviewed, with discussions on how Sirtuins and their activities may impact on the major etiological mechanisms of ALS. Here, we show that BRCA1 and the estrogen receptor alpha (ER-alpha) modulated vascular endothelial growth factor (VEGF) gene transcription and secretion in breast cancer cells. Although the stratified squamous component of the epithelia that lined the radicular cysts reported here may be derived from the cell rests of Malassez, the ciliated epithelial cells may be of sinus origin. Tumor volume as measured by 3D-EUS represents an independent risk factor for lymph node metastasis in early gastric cancer.

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Conformational restraint is a critical determinant of unnatural nucleotide recognition by protein kinases. A comprehensive search of bibliographic databases using combinations of text and index words relating to the population, prognostic markers and outcome will be undertaken with no language restrictions. A mobile clinical e-portfolio for nursing and medical students, using wireless personal digital assistants (PDAs). Perineural invasion (PNI) is the major mechanism of prostate cancer spread outside the prostate. The present systematic review gives an overview of original research papers on the education of prescribers and reporting outcomes on (potential) patient harm. The finding of tissue factor localized to platelet-leukocyte clusters suggests its blood-borne origin. Clinical studies are needed, however, to determine the value of this suggestion. Beta-MHC-hRARalpha transgenic hearts show heterogeneous re-expression of (early) sarcomeric genes while expression of connexin43, N-cadherin and beta-catenin is down-regulated. This article relates a theoretical framework developed by British codebreakers in World War II to the neural computations thought to be responsible for forming categorical decisions about sensory stimuli. As a first step toward characterizing these regulatory phenomena at the biochemical level, we report the development of an in vitro transcription system from cells of the B lymphoid lineage.

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Improving cell penetration of helical peptides stabilized by N-terminal crosslinked aspartic acids. Homozygous defects in a recently identified gene encoding transferrin receptor 2 lead to iron overload (hemochromatosis type 3) with symptoms similar to those seen in patients with HFE-associated hereditary hemochromatosis (hemochromatosis type 1). The optimal schedule, or whether embolization (TAE) alone gives the is it ok to drink alcohol while taking levaquin same survival advantage, is not known. In contrast to phytophagous insect species, little attention has been paid to the possibility of host races in the Drosophilidae, although flower-breeding species, where courtship and mating take place on the flowers, are likely candidates. Angiotensin II evokes calcium-mediated signaling events in isolated dog pancreatic epithelial cells. The use of anthelmintics is strongly limited in organic farming.

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According to the oncological protocol she has had extended hysterectomy Piver III type and partial pelvic lymphadenectomy. The analogues differ in the side chains of the macrocycle and in part contain zinc instead of the central magnesium. The frequency distribution of the underlying causes depends on the sector of the healthcare system in which it is ascertained. In the proposed study, the heart sound of patients having pulmonary hypertension will be captured by an electronic stethoscope and processed into digital sound spectra which will be analysed to identify a specific heart sound pattern. We developed evidence-based guidelines using systematic literature searches, with specific criteria for the selection and quality assessment of articles, and a clear and transparent decision-making process. Characterization of isolated acidocalcisomes from Toxoplasma gondii tachyzoites reveals a novel pool of hydrolyzable polyphosphate. Prevalence of visual, hearing, speech, physical, intellectual and mental disabilities in China, 2006.

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Polysaccharide covalently linked to the peptidoglycan of the cyanobacterium Synechocystis sp. The purpose of this study was to determine the mechanical transduction properties of intercostal muscle mechanoreceptors finasteride medication cost in response to controlled length and velocity displacements of the intercostal space. Cervical cancer is the only gynecological tumor staged clinically. Structural analysis of fertilization in the fish Brycon orbignyanus. Infant covariates included birth weight and feeding practices, longitudinal growth and nutritional status, hemoglobin and iron status captured at birth, and 6 and 12 months of age.

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However, cinical evaluation represents the most important tool to recognize the necessity for device optimization. Background Ambulatory blood pressure monitoring (ABPM) has been used increasingly in assessing dialysis patients. Similarities between the insulin-like stimulatory effect of human IgG and NSILP. Automation can enhance experimental throughput and will facilitate the parallel evaluation of competing biocatalyst and process options. Stricture of the upper digestive tract is the most feared sequelae of caustic ingestion. NGF triggers adult-like responding to spatial novelty in developing mice and such effect is gender-specific. Are Existing Risk Scores for Nonvalvular Atrial Fibrillation Useful for Prediction or Risk Adjustment in Patients With Chronic Kidney Disease?. Physician attitudes toward participating in a financial incentive program for LDL reduction are associated with patient outcomes. This up-regulation of circulating SL titres preceded the winter inhibition of feeding, and it was more severe in big fish (spring and summer stocking times) than in small fish (autumn stocking time), growing with a relative high efficiency during the cold season despite of a severe hypertriglyceridemia and a high hepatosomatic index. The efficacy of the third pump inhibitor--pantoprazole--in the short-term treatment of Chinese patients with duodenal ulcer.

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