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Antram (Tramadol)

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Antram is an oral medication that is used to help relieve ongoing moderate to moderately severe pain. Antram is similar to opioid (narcotic) analgesics. It works in the brain to change how your body feels and responds to pain.

Other names for this medication:
Arodol, Arrestadol, Atdol, Axedol, Bludol, Contradoc, Cormadol, Cradol, Decotram, Dolfre, Dolocet, Dolomed, Dolotram, Doltel, Drobit, Euphodol, Gemodol, Inodol, Kamadol, Madol, Midol, Neutram, Nobligan, Nopidol, Postadol, Radol, Rybix, Sedate, Siatram, Simol, Tamody, Tandam, Taxidol, Topspas, Traceta, Tramaflam, Tramasol, Tramataur, Tramdop, Tramoflex, Trapain, Trasic, Tridol, Trugesic, Typhon, Urogendo

Similar Products:
Thorazine, Artane, Anafranil, Urispas, Chloromycetin, Dilantin, Catapres, Micardis, Xenical, Sovaldi

Also known as: Tramadol


{name} ER is an pain medicine similar to an opioid. This medicine is used to treat moderate to severe pain.

The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.


Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Antram: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Antram is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Antram dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Antram are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Antram ER if you are allergic to it, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Antram ER should not be given to a child younger than 12 years old. Antram ER should not be given to anyone younger than 18 years old.

Do not give Antram ER to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Antram ER. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

Tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use Antram ER during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using Antram ER if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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Effects of prostaglandins and cholera enterotoxin on intestinal mucosal cyclic AMP accumulation. To investigate the response of retinal vessel diameters to photocoagulation treatment and their role for the success of laser treatment in patients with retinal vein occlusion. This was attributed to the proportionally large amount of fentanyl used. Different concepts to integrate expression data with interactome data and example studies are explained. The bispectral index (BIS), a processed variable derived from the raw electroencephalogram (EEG) used to guide sedation in the intensive care unit (ICU), has not been tested during barbiturate therapy for elevated intracranial pressure. Methods of three-dimensional analysis of axial computed tomographic images have recently been described. dsrD was transferred to and expressed in Lactococcus lactis MG1363. Partial purification and reconstitution of the heme oxygenase system from pig spleen microsomes. The structure model of the E protein revealed that YAEYI and LD/NLPW were located on domain (D) II, which confirmed that DII might contain a type-specific non-neutralizing epitope.

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Ligand-dependent disorder of the Omega loop observed in extended-spectrum SHV-type beta-lactamase. The dichotomous scoring model, item calibration, person calibration, logit scale, normative scale score, reliability, and validity are explained. Here we synthesize 30 y of research with new insights into their molecular functions and mechanisms of action. We report a case of a 38-yr-old man with a spontaneously ruptured gastric stromal tumor presenting as hemoperitoneum in outpatient clinic. DON-amended diets did however, cause dose-dependent decreases in the terminal organ weights recorded (thymus, spleen, liver, kidney and brain). Deletion and mutation analysis indicated existence of individual Cdc42-binding sites in the zizimin1 monomers. Direct and antibody-dependent cellular cytotoxicity was assessed using lactate dehydrogenase release assays.

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To tackle the pattern recognition problems first we give a new interpretation to the multi-dimensional fuzzy reasoning and then realize that new interpretation through a backpropagation type neural network. IgG1 monoclonal antibody was generated, and called mAbP6E7, in mice against a 70-kDa glycoprotein (gp70) of S. Characterization of ultrafiltration of undiluted and diluted stored urine. Moreover, we propose primarily electrostatic roles for the R96 and E222 side chains in chromophore formation and suggest that the T62 carbonyl oxygen is the base that initiates the dehydration reaction. Trout hepatoma: fibrosis and lymphocytosis as suppressive mechanisms in the rainbow trout (Salmo gairdneri). In the housefly Musca domestica, synthesis of yolk proteins (YPs) depends on the level of circulating ecdysteroid hormones. This work proposes to investigate the time course of changes in epinephrine and norepinephrine concentration in adrenal gland obtained from rats submitted to acute immobilization stress. These effects were specific for myostatin, as mRNA levels of glyceraldehyde-3-phosphate dehydrogenase and glucose-6-phosphatase were unchanged. Here we will review this reciprocal relationship: the effects of hematopoietic cells on OBs.

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The purpose of this study was to evaluate the endothelial expression of functionally active endothelial L-selectin ligands, sulfated sialyl Lewis x, in maxillary sinus mucosa from patients with chronic rhinosinusitis and from normal control subjects. LC/MS determination of bisphenol A in river water using a surface-modified molecularly-imprinted polymer as an on-line pretreatment device. Various immunological reactions have been demonstrated in vitro which could be of relevance to pathogenesis, including antibodies in serum directed against antigens expressed on the liver cell membrane, antibody-dependent cell-mediated cytotoxicity for autologous hepatocytes. In this work, polymeric micelles made from hydrophobized hyaluronic acid (HA) were probed for skin delivery. GBM stem cells have molecular hallmarks of neural stem and progenitor cells and it is possible to propagate both non-transformed normal neural stem cells and GBM can zithromax treat a bladder infection stem cells, in defined, feeder-free, adherent culture. Telomeres are repetitive sequences of DNA and associated proteins, which form a loop (t loop) at chromosome ends. This data suggests that encapsulation of streptokinase could provide a therapeutic option for treatment of thrombosed arteries.

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Quantitative analysis of matrix metalloproteinase-2 mRNA expression in central and peripheral regions of gliomas. Our objective was to estimate the influence of concealing clothes and other risk factors for vitamin D deficiency in women aged 20 to 50 years consulting general practitioners. In many cases, the constraints achievable from cosmology will surpass existing bounds from laboratory experiments and astrophysical observations by orders of magnitude. In contrast, the IL-1 beta tissue concentration was higher during the active than during the inactive phase. Thus acute inflammation triggers the activation of nuclear protooncogenes and alpha-feto-protein gene in hepatocytes, but this activation is not followed by passage into the replicative cycle. Preparation of a syrup with Bakis roots (Tinospora bakis) and evaluation of its choleretic activity in rats. mAb blocking experiments suggested the involvement of the CD2/LFA-3 but not the LFA-1/ICAM-1 pathway in monocyte regulation of T cell synthesis of IFN-gamma. Evaluation of agar-gel double diffusion for the diagnosis of adenovirus infection.

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Silencing Bax with a specific small interfering RNA blocked manumycin-induced mitochondrial condensation and cytochrome c release, arguing the dependence of manumycin-induced apoptosis on Bax. Checkerboard analysis indicated that LPA stimulated both the chemotactic and chemokinetic migration of DLD1 cells. Comparison of longitudinal biomechanical adaptation to shoe degradation between the dominant and non-dominant legs during running. Factor Xa inhibitors in acute coronary syndromes: moving from mythology to reality. Heparin-related complications have been explored only anecdotally and retrospectively, even though the risk of hemorrhage would depend on the magnitude of the prolongation of PTTa. The nanoparticle distribution was further used to model the dose distribution of two other radionuclides. Passively acquired antibodies were detected as long as 7 months after birth. The long-term benefit of this technical modification remains to be proven. Molecular structure and mechanism of functioning of cytochrome P-450. Anatomical and Clinical Study of the Posterior Auricular Artery Angiosome: In Search of a Rescue Tool for Ear Reconstruction.

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Variation in leaf trichomes and nutrients of Wigandia urens (Hydrophyllaceae) and its implications for herbivory. Tumors involving the tectal region constitute a distinct subgroup of brain stem gliomas with an indolent clinical course. Immunohistochemically, EMA and CK8 were positive in all cases, CK18 in five cases, CKHMW in two cases. Our result showed that female rats in the proestrous and estrous phases were less sensitive to the disruption of PPI by MDMA. SELF REPORTED TOOTH DISCOLORATIONS AMONG PATIENTS SEEN AT DENTAL CENTER UNIVERSITY COLLEGE HOSPITAL IBADAN. The aural power absorbed is proportional to the product of mean-squared forward pressure, ear-canal area, and absorbance, in which the sound field is represented using forward (reverse) waves traveling toward (away from) the eardrum. Occult spinous process fractures associated with interspinous process spacers. Infection with the human immunodeficiency virus (HIV) is associated with an in vivo increase in B lymphocyte activation and immaturity.

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