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Antram (Tramadol)
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Antram

Antram is an oral medication that is used to help relieve ongoing moderate to moderately severe pain. Antram is similar to opioid (narcotic) analgesics. It works in the brain to change how your body feels and responds to pain.

Other names for this medication:
Arodol, Arrestadol, Atdol, Axedol, Bludol, Contradoc, Cormadol, Cradol, Decotram, Dolfre, Dolocet, Dolomed, Dolotram, Doltel, Drobit, Euphodol, Gemodol, Inodol, Kamadol, Madol, Midol, Neutram, Nobligan, Nopidol, Postadol, Radol, Rybix, Sedate, Siatram, Simol, Tamody, Tandam, Taxidol, Topspas, Traceta, Tramaflam, Tramasol, Tramataur, Tramdop, Tramoflex, Trapain, Trasic, Tridol, Trugesic, Typhon, Urogendo

Similar Products:
Thorazine, Artane, Anafranil, Urispas, Chloromycetin, Dilantin, Catapres, Micardis, Xenical, Sovaldi

Also known as: Tramadol

Description

{name} ER is an pain medicine similar to an opioid. This medicine is used to treat moderate to severe pain.

The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.

Dosage

Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Antram: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Antram is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Antram dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Antram are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Antram ER if you are allergic to it, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Antram ER should not be given to a child younger than 12 years old. Antram ER should not be given to anyone younger than 18 years old.

Do not give Antram ER to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Antram ER. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

Tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use Antram ER during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using Antram ER if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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Distribution of cervical metastases from carcinoma of the cervicofacial region. Hence, in the system described, hapten-specific Tc did not lyse anti-hapten antibody-producing B cells to any measurable extent, and suppression of a B-cell response by in vivo or in vitro-induced Ts was independent of cytotoxic T-cell activity. Only on the times of driving, RR50 was significantly higher in the morning than that in the afternoon. However, details of the fetal development of these structures remain obscure. The HiT reports to 31 European health systems were analyzed using a qualitative content analysis and a process of meaning condensation. Gastric localization of Leishmania in a patient with acquired immunodeficiency syndrome. The results suggest that the quantitative morphological features of tumor pathological images predict prognosis in patients with lung cancer. Cell migration is an essential process involved in crucial stages of tissue formation, regeneration or immune function as well as in pathological processes including tumor development or metastasis. We excluded studies comparing mono- with multiphasic pills, and crossover trials with trials in which the difference in total content of ethinyl estradiol between preparations exceeded 105 micro g. Three-dimensional echocardiography, inotropic therapy, cardiac pacing, and mechanical circulatory support always were available and performed as needed.

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Effects of prostaglandins and cholera enterotoxin on intestinal mucosal cyclic AMP accumulation. To investigate the response of retinal vessel diameters to photocoagulation treatment and their role for the success of laser treatment in patients with retinal vein occlusion. This was attributed to the proportionally large amount of fentanyl used. Different concepts to integrate expression data with interactome data and example studies are explained. The bispectral index (BIS), a processed variable derived from the raw electroencephalogram (EEG) used to guide sedation in the intensive care unit (ICU), has not been tested during barbiturate therapy for elevated intracranial pressure. Methods of three-dimensional analysis of axial computed tomographic images have recently been described. dsrD was transferred to and expressed in Lactococcus lactis MG1363. Partial purification and reconstitution of the heme oxygenase system from pig spleen microsomes. The structure model of the E protein revealed that YAEYI and LD/NLPW were located on domain (D) II, which confirmed that DII might contain a type-specific non-neutralizing epitope.

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Ligand-dependent disorder of the Omega loop observed in extended-spectrum SHV-type beta-lactamase. The dichotomous scoring model, item calibration, person calibration, logit scale, normative scale score, reliability, and validity are explained. Here we synthesize 30 y of research with new insights into their molecular functions and mechanisms of action. We report a case of a 38-yr-old man with a spontaneously ruptured gastric stromal tumor presenting as hemoperitoneum in outpatient clinic. DON-amended diets did however, cause dose-dependent decreases in the terminal organ weights recorded (thymus, spleen, liver, kidney and brain). Deletion and mutation analysis indicated existence of individual Cdc42-binding sites in the zizimin1 monomers. Direct and antibody-dependent cellular cytotoxicity was assessed using lactate dehydrogenase release assays.

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Furosemide had no effect on the altered ion content, shrinkage, or on SNP-induced relaxation. Expression of the envelope glycoprotein did not appear to alter significantly the properties of the transformed cells in culture. In addition, we found that LHb inputs to the aVTA are dorsoventrally ordered. Communications between neurons involve synapses formed between axons of the presynaptic neurons and dendrites of the postsynaptic neurons. We have applied the present platform to multiple modes of cell migration assays including the accurate cell migration assay, competitive cell migration assay, biomimetic chemotaxis assay, and multifactor cell migration assay based on the organ-on-a-chip concept, for demonstrating its versatility, applicability, and potential in cell migration-related research. Case series of reports, submitted to the Adverse Drug Event Reporting System of the Food and Drug Administration. Group independent component analysis was performed to investigate training-related changes in functional connectivity. Alpha-2 agonist-induced memory impairment is mediated by the alpha-2A-adrenoceptor subtype.

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A monoclonal antibody directed against the vascular endothelial growth factor (VEGF) has been shown to be a potent neo-vascularisation inhibitor (bevacizumab). Extended systems driven through strong disorder are modeled generically using coarse-grained degrees of freedom that interact elastically in the directions parallel to the drive and slip along at least one of the directions transverse to the motion. Direct and indirect effects of predation, herbivory and surface rugosity on mussel recruitment. Potentiation of phencyclidine-induced dopamine-dependent behaviors in rats after pretreatments with serotonin-depletors. WBC/PMN counts remained at increased levels until 48 h postoperatively. The p47 gene was predicted to encode a 59-kDa peptide, but affinity-purified p47 had a molecular mass of approximately 47 kDa, as determined by polyacrylamide gel analysis. bromivora harbors a haplo-lethal allele that is linked to one mating type region. dilatation alone, dilatation followed by esophagocoloplasty, dilatation after cervical esophagostomy with or without an esophagocoloplasty, pectoralis major or sternocleidomastoid myocutaneous flap inlays with or without esophagocoloplasty, pharyngocoloplasty with tracheostomy, and neck exploration followed by esophagocoloplasty if a lumen was found in the cervical esophagus. Effect of cardioactive compounds on myocardial actomyosin in the centrifuged rat. The second phase involved looking at afferent inputs from brainstem nuclei.

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Although having distinct biological features and clinical outcomes, it is frequently misdiagnosed as primitive neuroectodermal tumor/medulloblastoma. The adenosine receptor antagonist CGS15943 reinstates cocaine-seeking behavior and maintains self-administration in baboons. However, the link between genotype and disease transmission route has not been closely examined. Older age and second skin cancer as prognostic factors in localized malignant melanomas. Here, we studied the distribution of Anopheles vectors of malaria in relation to environmental variables in Iran. Psychotropic drug-induced weight gain alleviated with orlistat: a case series. IL-4 production cycled directly with increased IgE levels in serum.

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To tackle the pattern recognition problems first we give a new interpretation to the multi-dimensional fuzzy reasoning and then realize that new interpretation through a backpropagation type neural network. IgG1 monoclonal antibody was generated, and called mAbP6E7, in mice against a 70-kDa glycoprotein (gp70) of S. Characterization of ultrafiltration of undiluted and diluted stored urine. Moreover, we propose primarily electrostatic roles for the R96 and E222 side chains in chromophore formation and suggest that the T62 carbonyl oxygen is the base that initiates the dehydration reaction. Trout hepatoma: fibrosis and lymphocytosis as suppressive mechanisms in the rainbow trout (Salmo gairdneri). In the housefly Musca domestica, synthesis of yolk proteins (YPs) depends on the level of circulating ecdysteroid hormones. This work proposes to investigate the time course of changes in epinephrine and norepinephrine concentration in adrenal gland obtained from rats submitted to acute immobilization stress. These effects were specific for myostatin, as mRNA levels of glyceraldehyde-3-phosphate dehydrogenase and glucose-6-phosphatase were unchanged. Here we will review this reciprocal relationship: the effects of hematopoietic cells on OBs.

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Anemia affects the health-related quality of life and impacts prognosis and outcome of therapy. Many studies have found that language comprehension involves sensory-motor system. Mice were sensitized and orally challenged with ovalbumin-coated encapsulated particles to induce eosinophil-associated gastrointestinal disease, and bronchial responsiveness was examined. The exclusionary guidelines presented provide a framework utilized at 1 institution for consideration of requests for PMSR and dramatically decreased the number of postmortem sperm retrievals performed. As neutron radiography is even more in demand for industrial applications of aircraft, turbine blade, automobile, explosive igniters, etc, it is necessary to review the standards which are the most appropriate for preparing the procedures for setting up the QA system. Different types of pain patients used visual analogue scales (VAS) to rate their level of pain sensation intensity (VAS sensory) and degree of unpleasantness (VAS affective) associated with pain experienced at its maximum, usual, and minimum intensity. These diabatic states are constructed to ensure that the first-order nonadiabatic couplings with respect to the one-dimensional transferring hydrogen coordinate vanish exactly. Anasarca caused by Cryptococcus neoformans after heart transplantation.

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The effect of social support and acculturation on postpartum depression in Mexican American women. Complex evolutionary history of the Aeromonas veronii group revealed by host interaction and DNA sequence data. Letter: Accurate quantitative estimation of lactate in whole blood. Metacognition and self-regulation are processes extremely relevant to education of persons with intellectual disabilities. Females mated to lead exposed male mice showed a nonsignificantly lower frequency of resorptions compared to controls. Their structures have been established as olean-12-en-3beta-ylacetate-29-oic acid, fern-22(29)-en-3beta,12beta-diol and fem-22(29)-en-3alpha,12beta-diol, respectively, on the basis of spectral data analysis and chemical reactions.

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A combination of these systems, in the context of the canine model, has the potential to improve the safety of osteoarthritis gene therapy vectors. Effectiveness of parent-centred interventions for the prevention and treatment of childhood overweight and obesity in community settings: A Systematic Review. At rest, there was no difference in platelet morphology or specific platelet proteins between the 3 groups. Patient 1 was a 50-year-old male who died of thyroid cancer and had worked at a printing house for 38 years. Cyclosporine A (CsA) has improved short-term results in renal transplantation. Multiple flexible structure alignment using partial order graphs. As a result of these effects on the intestinal mucosa, maintenance of sufficient vitamin D status may be essential for the development of a healthy gut microbiota, particularly in conditions defined by chronic mucosal inflammation such as CF. Percutaneous transluminal coronary angioplasty: evolution and changing concepts. The method depends on measuring the concentration of the photosensitizer (such as dihematorporphyrin ether), the flux density of the light, and the relative photodynamic effectiveness.

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The purpose of this study was to evaluate the endothelial expression of functionally active endothelial L-selectin ligands, sulfated sialyl Lewis x, in maxillary sinus mucosa from patients with chronic rhinosinusitis and from normal control subjects. LC/MS determination of bisphenol A in river water using a surface-modified molecularly-imprinted polymer as an on-line pretreatment device. Various immunological reactions have been demonstrated in vitro which could be of relevance to pathogenesis, including antibodies in serum directed against antigens expressed on the liver cell membrane, antibody-dependent cell-mediated cytotoxicity for autologous hepatocytes. In this work, polymeric micelles made from hydrophobized hyaluronic acid (HA) were probed for skin delivery. GBM stem cells have molecular hallmarks of neural stem and progenitor cells and it is possible to propagate both non-transformed normal neural stem cells and GBM can zithromax treat a bladder infection stem cells, in defined, feeder-free, adherent culture. Telomeres are repetitive sequences of DNA and associated proteins, which form a loop (t loop) at chromosome ends. This data suggests that encapsulation of streptokinase could provide a therapeutic option for treatment of thrombosed arteries.

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Quantitative analysis of matrix metalloproteinase-2 mRNA expression in central and peripheral regions of gliomas. Our objective was to estimate the influence of concealing clothes and other risk factors for vitamin D deficiency in women aged 20 to 50 years consulting general practitioners. In many cases, the constraints achievable from cosmology will surpass existing bounds from laboratory experiments and astrophysical observations by orders of magnitude. In contrast, the IL-1 beta tissue concentration was higher during the active than during the inactive phase. Thus acute inflammation triggers the activation of nuclear protooncogenes and alpha-feto-protein gene in hepatocytes, but this activation is not followed by passage into the replicative cycle. Preparation of a syrup with Bakis roots (Tinospora bakis) and evaluation of its choleretic activity in rats. mAb blocking experiments suggested the involvement of the CD2/LFA-3 but not the LFA-1/ICAM-1 pathway in monocyte regulation of T cell synthesis of IFN-gamma. Evaluation of agar-gel double diffusion for the diagnosis of adenovirus infection.

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Silencing Bax with a specific small interfering RNA blocked manumycin-induced mitochondrial condensation and cytochrome c release, arguing the dependence of manumycin-induced apoptosis on Bax. Checkerboard analysis indicated that LPA stimulated both the chemotactic and chemokinetic migration of DLD1 cells. Comparison of longitudinal biomechanical adaptation to shoe degradation between the dominant and non-dominant legs during running. Factor Xa inhibitors in acute coronary syndromes: moving from mythology to reality. Heparin-related complications have been explored only anecdotally and retrospectively, even though the risk of hemorrhage would depend on the magnitude of the prolongation of PTTa. The nanoparticle distribution was further used to model the dose distribution of two other radionuclides. Passively acquired antibodies were detected as long as 7 months after birth. The long-term benefit of this technical modification remains to be proven. Molecular structure and mechanism of functioning of cytochrome P-450. Anatomical and Clinical Study of the Posterior Auricular Artery Angiosome: In Search of a Rescue Tool for Ear Reconstruction.

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Variation in leaf trichomes and nutrients of Wigandia urens (Hydrophyllaceae) and its implications for herbivory. Tumors involving the tectal region constitute a distinct subgroup of brain stem gliomas with an indolent clinical course. Immunohistochemically, EMA and CK8 were positive in all cases, CK18 in five cases, CKHMW in two cases. Our result showed that female rats in the proestrous and estrous phases were less sensitive to the disruption of PPI by MDMA. SELF REPORTED TOOTH DISCOLORATIONS AMONG PATIENTS SEEN AT DENTAL CENTER UNIVERSITY COLLEGE HOSPITAL IBADAN. The aural power absorbed is proportional to the product of mean-squared forward pressure, ear-canal area, and absorbance, in which the sound field is represented using forward (reverse) waves traveling toward (away from) the eardrum. Occult spinous process fractures associated with interspinous process spacers. Infection with the human immunodeficiency virus (HIV) is associated with an in vivo increase in B lymphocyte activation and immaturity.

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