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Anxyl (Alprazolam)

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Anxyl is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Anxyl is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Anxyl may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Alpraday, Alpron, Alprowon, Andep, Anlzium, Anxofit, Anxyl, Balzam, Endolam, Fluprax, Jolistar, Mcalm, Mebasap, Mebrin, Mediprex, Restyl, Sanprazole, Somnia, Tancalm, Tenlax, Tensyl, Trazopin, Viprax, Wycalm, Zepro, Zomark, Zopax, Zotam

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Aldactone, Intagra, Mircette, Biaxin, Colospa, Furadantin, Ticlid, Trandate, Casodex, Nizoral

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Anxyl XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Anxyl XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Anxyl XR dosage information

Side effects

The most common side effects associated with Anxyl are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Anxyl if:

you also take itraconazole or ketoconazole (antifungal medicines); or you have a history of allergic reaction to any benzodiazepine (alprazolam, diazepam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Valium, Versed, and others).

To make sure Anxyl is safe for you, tell your doctor if you have ever had:

breathing problems such as COPD (chronic obstructive pulmonary disease) or sleep apnea (breathing that stops during sleep); drug or alcohol addiction; depression, mood problems, or suicidal thoughts or behavior; or kidney or liver disease (especially alcoholic liver disease).

Tell your doctor if you are pregnant or plan to become pregnant. Alprazolam may harm an unborn baby. Avoid taking this medicine during the first trimester of pregnancy.

If you use Anxyl while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

You should not breastfeed while using alprazolam.

Anxyl is not approved for use by anyone younger than 18 years old.

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In contrast to the pattern of expression described for most LTP-like genes from dicots, Northern blot analyses detected constitutive expression of Ha-LTP5 in seeds, but not in aerial parts of sunflower plants. Spectral detector computed tomography (SDCT) is a novel technology that uses two layers of detectors to simultaneously collect low and high energy data. Functional expression of the human breast cancer resistance protein in Pichia pastoris. Levels of CA-125, CA 19-9 and CA 15-3 in the peritoneal fluid were determined by immunoradiometric assay. There is increasing evidence that mouse cells of different strains contain different numbers and biologic classes of naturally-integrated type-C RNA viruses. This identifies BB-94 as a simultaneous anti-apoptotic and anti-inflammatory molecule during MTB infection. Adult male body condition remained relatively stable throughout the year, but females experienced considerable variation.

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Sleep disruption is a common feature both in the patients with chronic cough and in the patients with obstructive sleep apnea syndrome (OSAS). Universal plasma is intended to be transfused irrespective of the blood group. We report three patients who underwent successful endovascular AAA repair in whom postoperative surveillance showed aneurysm regression, yet delayed AAA enlargement without demonstrable endoleak developed in all three patients. Study of water vapor and surfactant absorption by lipid model systems using the quartz crystal microbalance. We found that retardation of cell cycle periods in certain cell lineages and thus a change in the normal order of cell divisions is compatible with development to a hatching juvenile. Of particular interest was the recognition of distal pathways that strongly correlated with a particular hepatic function. Nonrhabdomyosarcoma soft tissue sarcomas are a heterogeneous group of tumors for which optimal treatment remains controversial. Neither breathing frequencies nor CT density measurements revealed differences between the groups.

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Abstracts of the 1st Central European Congress on Intensive Care Medicine. We focus on the fractal features of the spectral entropy and analyze its characteristic intermediate time scales as a function of the nonlinear coupling. Well-baby check-up data at 1 month and at 12 months of age were used. This report serves as a reminder that masses associated with cryptococcal infection should be included on the differential list for cats with intracranial masses. Experimental results indicate that the constructed model is much superior to models using single algorithm and other models that only adopt feature selection procedure or algorithm selection procedure. PUE, however, demonstrated distinct altitudinal patterns to generate an intricate conrol of P use pattern by soil P pools and altitude. The role of intra-plaque inflammation in this response to surgical injury remains to be fully elucidated. Mid-term functional outcome of a total arthroplasty of the first metatarsophalangeal joint. To evaluate plication of the free wall of the left ventricle, which reduces the left ventricular area and volume, as a method to improve the left ventricular systolic function without cardiopulmonary bypass. Test-retest statistics demonstrated that the long-range temporal correlations had significant reliability, which was greatest in the closed-eyes condition.

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Research on conformational changes of trypsin in different concentrations of GuHCl by fluorescence spectra. The effectiveness of these procedures for detecting mild disturbances in vocal quality in elite vocal performers has been controversial. The low-temperature crystal stuctures of D- and DL-camphoric anhydride, C(10)H(14)O(3), have been determined by X-ray diffraction methods. As the young adult matures, increasingly phosphorylated variants are generated following a precise ontogenetic progression. However, the interaction of CRP with phosphorylcholine-based biomaterials is unknown due to the lack of our understanding on the activation mechanism of CRP in altered local microenvironments. Mercuric chloride was injected into the triceps surae muscle of adult male Wistar rats. Polyphyllin G induces apoptosis and autophagy cell death in human oral cancer cells. The results presented in this article could be of use to both the emergency physician treating patients involved in motor vehicle collisions as well as the engineer involved in occupant design countermeasures. Regional structuring of genetic variation in short-lived rock pool populations of Branchipodopsis wolfi (Crustacea: Anostraca).

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Dynamic association of band 3 with triton shells in human erythrocyte ghosts. and Anisakis pegreffii (Nematoda: Anisakidae) in an area of sympatry. Chronic superficial keratitis in dogs: negative results of isolation procedures for Chlamydia. The vacuum UV radiation absorbed by biomolecules may initiate luminescence, photodestruction and photoionization processes which lead to distortions or damage of the molecular structure. Lanthanide 8-hydroxyquinoline-based podates with efficient emission in the NIR range. Parametric survival model was used to assess factors associated with the day of discharge. The glutaraldehyde group exhibited little cusp calcification, but prominent aortic wall calcification. In addition to an ageing population and potential economic incentives, technical innovations and new implant systems should be considered when discussing increasing case numbers. Another additional bhPET focus did not have a morphological correlate.

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Identification of Muscidae (Diptera) of medico-legal importance by means of wing measurements. In order to know the adaptive changes of small intestine regions (duodenum, and proximal, medial and distal jejunum-ileum) due to the reproductive stage (virgin, pregnancy and lactation), the weight, mucosal proportion, mucosal DNA and protein contents and protein/DNA ratio in female Wistar rats were measured. In the attempt to verify these reports, we analyzed specimens obtained from a representative group of Polish patients. A chapter from lamaze history: birth narratives and authoritative knowledge in france, 1952-1957. Indirect effects of fish on macrophytes in Bays Mountain Lake: evidence for a littoral trophic cascade. During hemodialysis, the intracranial pressure transiently increases and rapidly recovers. One-way sensitivity analyses showed that initial laparoscopic exploration was less costly if the operative time of laparoscopic exploration did not exceed 19 minutes and the cost of disposable laparoscopic equipment was less than 147 US dollars. Its incidence has increased in the last years and goes on getting diagnostic and therapeutic problems. Fibroblast growth factor receptor 3 gene: regulation by serum response factor. Humans typically exhibit a tendency to follow the gaze of conspecifics, a social attention behaviour known as gaze cueing.

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Surfactants: their role in preventing the precipitation of proteins by tannins in insect guts. The findings support that MSC can be transplantable between HLA-incompatible individuals. In both experiments, disease challenge in the absence of feed additives demonstrated significant reductions in performance as measured by weight gain, feed conversion, and the incidence of coccidial lesion scores. However, the actual presence of markers in the conduction system and its developmental mode remain controversial. Our results demonstrate that TGCE is a highly sensitive method for mutation detection and has utility for mutation discovery analysis.

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The change in SUVmax (retention index, RI) was defined as the ratio of increase in SUVmax between the early and delayed scans to the SUVmax in the early scan. Analysis of G/A polymorphism in the androgen response element I of the PSA gene and its interactions with the androgen receptor polymorphisms. A new method for vaginal reconstruction using a pedicled jejunal flap. IL-12 appeared to play different roles in the pathogenesis of allergic diseases between younger and older ages. After gonioimplant placement, IOP was controlled for a variable period in all dogs. There were 673,141 patients who presented to the ED during the study period and had a primary diagnosis of acute asthma. Heparanase-1 gene expression in normal, hyperplastic and neoplastic prostatic tissue. Traffic crash involvement: experiential driving knowledge and stressful contextual antecedents. Although significant progress has been made in molecular understanding of skeletal muscle differentiation, no information is available concerning the genes involved in development of the heart, the first organ to form in vertebrate embryos.

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Studies were included if they were randomized placebo-controlled trials with follow-up of at least 1 month. The 5A or 6A single nucleotide polymorphism (SNP) at the -1 171 bp site of promoter region of MMP-3 may modify the transcription and local expression of MMP-3. If symptoms occur frequently, long-term antiarrhythmic drug therapy is then indicated and will be effective for chronic prophylaxis in most individuals with a low risk of proarrhythmic events. Mas37p, a novel receptor subunit for protein import into mitochondria. Alkaline phosphatase (AP) is a phosphate transferase present in bacteria and eukaryotes. Three parameters affect the variance in morphometric findings: (1) knowledge about normal morphologic variability, (2) confounding physiologic parameters, and (3) methodologic misuse. Marital adjustment reported by the depressed group was significantly worse than that of the normal group. T-cell repertoire in the tonsils of patients with IgA nephropathy. The cytomorphology, an endothelial immunophenotype, and the appropriate clinical presentation should permit diagnostic consideration of EH in the differential diagnosis of an endothelial lesion.

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