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Apalene (Adapalene)

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Apalene works well for treating mild-to-moderate acne, but it can cause burning and itching right after using it. The medication has many different formulations, but only the lower strength gel is available over-the-counter.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Microzide, Addyi, Ceclor, Neoral, Dostinex, Remeron, Lioresal, Imovane

Also known as: Adapalene


Adapalene is used to treat acne. It works partly by keeping skin pores clear.

Adapalene is available only with your doctor's prescription.


Usual Adult Dose for Acne:

Apalene 0.1% cream, 0.1% gel, 0.3% gel: Apply to the affected area once a day at bedtime after washing. A thin film should be applied, avoiding eyes, lips, angles of the nose, and mucous membranes. Lotion: Apply a thin film of lotion to the entire face and other affected areas of the skin once daily, after washing gently with a mild soapless cleanser. Dispense a nickel size amount of lotion (3 to 4 actuations of the pump) to cover the entire face. Avoid application to the areas of skin around eyes, lips and mucous membranes.

Usual Pediatric Dose for Acne:

Apalene 0.1% cream, 0.1% gel, 0.3% gel: 11 years or less: Safety and efficacy have not been established. 12 to 18 years: Apply to the affected area once a day at bedtime after washing. A thin film should be applied, avoiding eyes, lips, angles of the nose, and mucous membranes. Safety and effectiveness of the lotion formulation in pediatric patients under the age of 12 have not been established.

Detailed Apalene dosage information


If you overdose Apalene and you don't feel good you should visit your doctor or health care provider immediately.


Store at a room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Apalene are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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In this study, we investigated the effects of coumestrol and other phytoestrogens on osteoclast differentiation using estrogen receptor alpha-transfected RAW264.7 (RAW264.7-ERalpha) cells. Eighteen patients with suspected steno-occlusive lesions of the intracranial arteries were studied with two types of three-dimensional time-of-flight angiography and conventional digital subtraction angiography. In all three cases of axillary nerve paralysis there was in addition a narrow quadrilateral space. Comparative evaluation of the safety of poly- and and oligoguanidines. The HIV epidemic has sharply increased the incidence, severity of, and mortality due to, childhood pneumonia. Prediction of cognitive decline after stroke using proton magnetic resonance spectroscopy. Although successful clinical use of cervical pedicle screws has been reported, anatomical studies have shown the possibility for serious iatrogenic injury. 24 immunohistochemical distribution of I kappaB proteins in normal mouse gastric mucosa. Long-term results of endobronchial brachytherapy: A curative treatment?. However, due to the lack of a suitable cell culture system, the pasteurization process has not been investigated in the past.

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Depressive disorder and its significance in psychosomatic medicine and psychotherapy. Combined radiofrequency thermal ablation and percutaneous cementoplasty treatment of a pathologic fracture. Occurrence of AmpC-positive Klebsiella pneumoniae strains in patients with haematological malignancies. Chronological age for the spontaneous resolution of vesicoureteral reflux. Two cases of neonatal listeriosis following Caesarean section are reported. Our results indicate that individuals who experience grapheme-colour synaesthesia outperformed controls on tasks involving fine visual discrimination of facial identity and emotion, but indocin gout medicine not on tasks involving holistic face processing.

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