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Apomatine (Metoclopramide)

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Apomatine antagonizes the effect of dopamine in the central nervous system and other organ systems. Apomatine's effect on the medullary chemoreceptor trigger zone makes it useful as a routine anti-emetic and in preventing vomiting induced by antineoplastic drugs, particularly cisplatin.

Other names for this medication:
Acimet, Actinorm, Apomatine, Cepar, Cerinorm, Clomet, Copar, Cosmet, Donmet, Elinorm, Emenil, Emenorm, Fenomet, Gastonorm, Maxinorm, Megatech, Metadrate, Metcon, Metocin, Metoclop, Metoclopramide, Metocontin, Metomit, Metoz, Metozolv, Metvo, Migrosh, Nausifar, Norvin, Nutec, Pacimol, Paramet, Paranorm, Perilan, Perinorm, Peronorm, Promet, Propamid, Pymet, Reglan, Rivnorm, Tomid, Vagonorm, Vominil, Vominorm, Vomitex, Vomitrac, Zerinorm

Similar Products:
Mellaril, Pepcid, Sustiva, Addyi, Soma, Compazine, Precose, Arava, Mestinon

Also known as: Metoclopramide


Cialis is a drug that is used for the treatment of erectile dysfunction or impotence. Its mechanism of action is based on the effect of tadalafil (the main active ingredient), which relaxes the smooth muscles in the walls of blood vessels in the pelvic organs. As a result, the blood flow rushes to the penis, filling up the cavernous body; the penis gets erected. If taken properly (in compliance with the instruction), Cialis is absolutely safe. But, like any drug, of course, it has certain contraindications and side effects.


Usual Adult Dose of Apomatine for Intraocular Hypertension:

One eye drop in the affected eye(s) once a day in the evening Comments: -If one dose is missed, treatment should continue with the next dose as normal. -The dose should not exceed one drop in the affected eye(s) daily as more frequent administration may lessen the intraocular pressure lowering effect. -Reduction of the intraocular pressure starts approximately 2 to 4 hours after the first administration with the maximum effect reached after 12 hours. -This drug may be used concomitantly with other topical ophthalmic drugs to lower intraocular pressure. -If more than one topical ophthalmic drug is being used, each one should be administered at least 5 minutes apart. Use: -Reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension

Usual Adult Dose of Apomatine for Glaucoma (Open Angle):

One eye drop in the affected eye(s) once a day in the evening Comments: -If one dose is missed, treatment should continue with the next dose as normal. -The dose should not exceed one drop in the affected eye(s) daily as more frequent administration may lessen the intraocular pressure lowering effect. -Reduction of the intraocular pressure starts approximately 2 to 4 hours after the first administration with the maximum effect reached after 12 hours. -This drug may be used concomitantly with other topical ophthalmic drugs to lower intraocular pressure. -If more than one topical ophthalmic drug is being used, each one should be administered at least 5 minutes apart. Use: -Reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension

Detailed Apomatine dosage information


If an overdose occurs and you are not feeling well, you should seek emergency medical attention or contact your healthcare provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Apomatine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Apomatine if you you are allergic to bisoprolol, or if you have a serious heart condition such as:

"AV block"; severe heart failure; or slow heartbeats that have caused you to faint.

To make sure Apomatine is safe for you, tell your doctor if you have:

congestive heart failure or other heart problems; coronary artery disease (hardened arteries); circulation problems (such as Raynaud's syndrome); asthma, chronic obstructive pulmonary disease (COPD), or other breathing disorder; diabetes (taking Apomatine can make it harder for you to tell when you have low blood sugar); liver or kidney disease; a thyroid disorder; or a history of allergies.

It is not known whether Apomatine is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether bisoprolol passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Apomatine is not approved for use by anyone younger than 18 years old.

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