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Aratan (Losartan)

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Aratan and associated names, 12,5 mg, 25mg, 50 mg, 100 mg, film-coated tablets is an orally active angiotensin II (Ang- II) receptor antagonist, Aratan, acting on the AT1 receptor subtype, thus blocking the effect of Ang-II in the renin angiotensin system (RAS) cascade. Aratan is indicated for the treatment of hypertension.

Other names for this medication:
Aratan, Asart, Cartan, Corus, Covance, Cozaarex, Czartan, Hilos, Hypozar, Losapres, Losarb, Losargamma, Losart, Lostan, Lostankal, Lozap, Lozitan, Osartan, Osartil, Portiron, Prelow, Ranlozar, Rasoltan, Sanipresin, Sartens, Sedeten, Tarnasol, Xartan

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Also known as: Losartan


Aratan is a perfect remedy, which helps to fight against the symptoms of high blood pressure and to reduce the risk of stroke in people with hypertension. Its target is to treat kidney problems in people with type 2 diabetes. Aratan is also known as Losartan potassium, Cosart, Los-Po. Aratan acts by preventing the hormone angiotensin II from constricting the blood vessels, which tends to raise blood pressure. It is angiotensin II receptor antagonists. Generic name of Aratan is Losartan Potassium. Brand name of Aratan is Aratan.


Take Aratan tablets orally with or without food. Do not crush or chew it. Take Aratan once or twice a day at the same time. If you want to achieve most effective results do not stop taking Aratan suddenly.


If you overdose Aratan and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Aratan overdosage: fainting, feeling lightheaded, rapid heartbeat.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Aratan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Use of drugs that act on the renin-angiotensin system during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. Resulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformations. Potential neonatal adverse effects include skull hypoplasia, anuria, hypotension, renal failure, and death. When pregnancy is detected, discontinue Aratan as soon as possible.

In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with Aratan. Correct volume or salt depletion prior to administration of Aratan.

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tuberculosis H37Ra, while there was a approximately 7.9-kb DraI fragment in M. Life-support circulation was established within 13 minutes and provided a stable period before surgery. The short-term benefit to bone mineral density in preterm infants of mineral supplementation of the early diet is obvious, but, in the long term, the effects seem to disappear. This is consistent with other studies suggesting that perception of psychiatry is enhanced following a clerkship but this does not translate into psychiatry as a career intention. Our data also indicated that the gradual unbinding of the chaperone from the PapA groove has increasingly strong structural consequences.

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Our study showed that the effect of light on germinating spores of Streptomyces was variable: some species were indifferent, whereas others, such as Streptomyces viridosporus, displayed a marked inhibition of CFU numbers on growth medium. Deletions or mutations in any of these genes may also cause a telomere defect resulting in accelerated telomere shortening, lack of end-capping function, and/or end-to-end chromosome fusions. Based on this new concept and fixed point theorem, the relationship between S-stability and stationary oscillation (i.e., existence, uniqueness and global stability of periodic solutions) for the nonlinear impulsive delayed system is explored. This work aimed to contribute to the characterization of membrane transport mechanisms, namely, extraneuronal monoamine transporter (EMT), the multidrug resistant protein 1 (MRP1), and P-glycoprotein (P-gp) in freshly isolated cardiomyocytes from adult rats. Most often they are significantly enlarged for solving the esthetic requests of the patients. Conductive hearing loss was identified using audiometry and tuning forks. Aesthetic correction of a hypertrophic sinus frontalis: a long-term follow-up evaluation and refinement of the method.

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They were fed either a standard pellet diet or a tungsten supplemented molybdenum-free diet. Microarray analysis of gene expression in peripheral blood mononuclear cells from dioxin-exposed human subjects. Role of the liver in the metabolism of the melanotropic hormone in the frog. Advances in gynecological radiotherapy by means of mobile irradiation, isotopes and electron accelerator (betatron). Nephaspis indus Gordon, 1996, a natural enemy of Aleurodicus dispersus Russell (Hemiptera: Aleyrodidae) native to the Neotropical region, is recorded as established in Taiwan for the first time. Magnetization transfer ratio (MTR) permits the quantitative estimation of cervical cord tissue damage in patients with multiple sclerosis (MS). Permanent restoration of a spontaneous rhythm was feasible only after administration of systemic thrombolysis with recombinant tissue plasminogen activator. Concentrations of suPAR and MBL, in addition to perioperative blood transfusion, were significantly associated with the development of postoperative pneumonia.

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Dynamic models can be used to predict the changing potential of the chemical state of an ecosystem under different acid depositions. Characterization of the human immune response to the UK anthrax vaccine. These results were consistent with the expression pattern of the respective genes. Ethanol-altered liver-associated T cells mediate liver injury in rats administered Concanavalin A (Con A) or lipopolysaccharide (LPS). The cost of non-urinary tract infections caused by ESBL-EK was 1.7 times the cost of non-urinary tract infections caused by non-ESBL producers.

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More research is needed in contemporary cohorts with larger sample sizes and more extreme ages of birth. This study assessed the efficacy of endoscopic intratumoral injection of cisplatin/epinephrine gel to relieve obstruction and improve swallowing. It presents technical data on a small-dose fluorograph with an X-ray image intensifier. The skinny on a growing problem: dry beriberi after bariatric surgery. COX-2 expression in highly aggressive thyroid malignancies - indication for a possible therapeutic option?. Individuals suffering from shingles may be sometimes contagious for susceptible children because of enormous amount of virus particles in vesicle fluid. Generation of internal solitary waves by frontally forced intrusions in geophysical flows. Histochemical control in biochemical estimation of prostatic phosphatase activity. Eryngium cuneifolium, the species with the narrowest range and fewest populations, has intermediate values for genetic parameters.

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To investigate the mechanisms by which Ras suppresses neuronal death, we examined whether Ras functions by inhibiting the proapoptotic p53 pathway (Jun-N-terminal kinase/p53/BAX) that is necessary for neuronal death after NGF withdrawal and p75NTR activation. Remarkable IL 2 production was also induced by OKT3 when latex beads coated with rabbit anti-mouse IgG2a antibody and TPA were added to the culture. Falstatin localizes to the periphery of rings and early schizonts, is diffusely expressed in late schizonts and merozoites, and is released upon the rupture of mature schizonts. Our data seems to indicate that embryonic heart vasculogenesis is accompanied by hematopoiesis. We measured the number of treatments each patient could remember that had been explained by the anesthetist on the visit, and found it was unexpectedly small at the interview. Increased Age, but Not Parity Predisposes to Higher Bacteriuria Burdens Due to Streptococcus Urinary Tract Infection and Influences Bladder Cytokine Responses, Which Develop Independent of Tissue Bacterial Loads. Shape orientation has also been used in computer vision to provide a properly oriented frame of reference, which can aid recognition. Hemorrhagic proctitis caused by Klebsiella oxytoca after administration of pristinamycin. The patterns in quantity, size and distribution of tumors revealed interesting aspects in the clinical manifestation of FP in specimens studied in Brazil, and that FP scoring systems developed for other areas might not perform adequately when applied to sea turtles on the Southwest Atlantic Ocean.

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A bank of gonococcal DNA was constructed in the lambda gt11 expression vector. Possible methodological problems of these studies, alternative hypotheses, and considerations for future research are noted. Results indicated that specific personality traits confer risk for suicidal behaviors in middle age and older adults. We compared 417 adults diagnosed under age 30 with 968 adults diagnosed ages 50-58 on clinical and social measures using standard parametric tests. Use of outpatient services was also higher in older populations. We reviewed all cases of SUD in infants aged 1 week to 18 months that occurred in the province of Quebec (Canada) between 1987 and 1996. Reversible inhibitors of monoamine oxidase inhibitor-A were the second choice to SSRIs for adolescents with major depression, patients aged over 65 years, patients with serious medical illnesses and patients with chronic fatigue. Diagnosing tuberculosis in the 21st century - Dawn of a genomics revolution?. We have mutated the type I cellular retinoic acid binding protein (CRABP-I), individually at the Arg131 (into Ala) and the Tyr133 (into Phe) residues which have been predicted to make direct contact with retinoic acid (RA) based upon previous structural studies.

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Assignment of paramagnetic (15)N-HSQC spectra by heteronuclear exchange spectroscopy. All bacteria tested were less susceptible in food systems than in vitro. gingivalis LPS on the cellular responses associated with mucin synthesis in sublingual salivary gland acinar cells. In the liver, some hepatocytes were strongly stained and some were less strongly positive for cathepsin B and L. We identified 12 CST in 8 of 19 patients with Muir-Torre syndrome (MTS). Furthermore, augmentation of cholinergic function by means of perinatal choline treatment enhances cognitive performance in a sex specific manner. The rank order of compounds in antagonizing the stimulus effects of 0.04 mg/kg fentanyl in dose-dose discrimination was naloxone greater than N-allylnormetazocine greater than cyclazocine greater than nalorphine.

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Undoubtedly, tumor development and growth can be influenced by the quantity of protein consumed by an animal, but the responses observed with specific tumors and carcinogens may differ. The Centre of pressure (CoP) excursions and the isometric maximal voluntary contraction (MVC) were measured before and after a fatiguing exercise. The dependence of the SHG signal on probe thickness was determined in forward and back scattering geometry. Our simple technique of rapid CT confirmation of AO dislocation is a practical adjuvant procedure, particularly in patients with suspected intracranial injury. Traumatic vascular injury to the intracranial and extracranial circulation can be sequelae of blunt, penetrating, or iatrogenic insults to the head, face, or neck. Results of a practical protocol for management of prenatally detected hydronephrosis due to ureteropelvic junction obstruction. Covariates of tactile sensation, disease duration, glycated hemoglobin, and clinical diagnosis of peripheral neuropathy were also assessed.

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Data of the interacting protein networks and nucleotide metabolism pathways related to NDK and NT5. An Exploratory Study of the Impact of Gender on Health Behavior Among African American and Latino Men With Type 2 Diabetes. Long-term survival following salvage surgery for persistent or locally recurrent epidermoid carcinoma of the anal canal can be achieved in the majority of patients. A decision analysis model was developed and sensitivity analyses were used to assess the incremental cost (dollars/quality-adjusted life-year) associated with the use of SDPs versus RDPs for adult patients undergoing hematopoietic progenitor cell transplantation or primary coronary artery bypass grafting (CABG). This review highlights research advances in food allergy that were published in the Journal in 2015. Performance evaluation of commercial short-oligonucleotide microarrays and the impact of noise in making cross-platform correlations. Staphylococcus aureus is the principal causative agent of the inflammatory bone disease osteomyelitis.

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There was no difference between hand-sewn and stapled anastomoses in the incidence of adhesive obstruction, stricture, or leak. Theoretical investigation of the binding energies of the iodide ion and xenon atom with decaborane. Occurrence of skin lesions during long-term therapy with hydroxyurea are well described, but there have been only a few case reports of longitudinal melanonychia associated with hydroxyurea treatment. Cancer therapy and osteoporosis: approach to evaluation and management. Thus, traffic through lymphatic vessels is mandatory before DCs relocate to lymph nodes where they are dedicated to T-cell priming. Women with menorrhagia, at high risk because of bleeding disorders (12), morbid obesity (6), heart-lung transplantation (2), cardiac pacemaker (2), postmenopausal bleeding (8), bowel disease with extensive adhesions and ileostomies (3), cervical stenosis (3), and other medical disorders (9). In longitudinal analyses, we found significant decreases in and associations with wellbeing over time in respondents fulfilling one PDF condition (mild PDF). These data show a protective effect of physical activity for incident exudative AMD, independent of body mass index and other tetracycline hcl 500 mg confounders.

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Effects of sulfur dioxide on mRNA expression and activities of hepatic and pulmonary cytochrome P4502B1 and 2E1 in rats. Further, correcting errors for minimum detectable levels and random errors simultaneously is too complex for analytical solutions. To compare two different methods, namely orthotopic implantation and armpit implantation, for establishing nude mouse model bearing osteosarcoma in light of the tumor formation rate and time, tumor growth changes and lung metastasis. We examined the breast and cervical cancer screening practices of 4,961 American Indian and Alaska Native women in 47 states from 1992 through 1997 by using data from the Behavioral Risk Factor Surveillance System. Misdiagnosing the problem: mental health profiles of incarcerated juveniles. If this initial management does not lead to satisfactory symptom control, extended diagnostics are indicated. In general, surface features of deactivated bacteria used for whole-cell bacterial vaccines affect the immunoresponse to bacteria-associated antigens. Male hypothalamic hypogonadism: induction of spermatogenesis by subcutaneous pulsatile gonadotrophin-releasing hormone. Intravenously administered plasmid DNA displayed similar levels of plasmid DNA in the nine different regions, whereas, intranasally administered plasmid DNA exhibited different levels of distribution among the regions, with the highest plasmid DNA levels in the olfactory bulb. Retinol acetate, tocopherol acetate, and phylloquinone administered in various pair combinations reduce the degree of changes in the parameters of nonspecific resistance and immunological reactivity.

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Appreciation was positively related to medication adherence behaviors for the past 6 months. These results confirm the function of (pro)systemin in the transduction of systemic wound signals and further establish that wounding, systemin, and 35S::prosys induce defensive gene expression through a common signaling pathway defined by at least three genes (Def-1, Spr-1, and Spr-2). Fissures in the subchondral bone were observed in computed tomographic images of 43 per cent elbows that had a stable fissure at arthroscopy. The mean entorhinal cortex volume of patients with schizophrenic disorders did not differ from that of patients with nonschizophrenic psychotic disorders. This transactivation capability was cell type specific and it was critically dependent on the contributions of the methyltransferase-homology (MT) region of MLL in combination with the C-terminus of ENL. The issues underlying this debate are complicated by the fact that these medications can be fairly effective in managing the symptoms and preventing relapse in schizophrenia and other psychotic disorders, yet these drugs have therapeutic limitations and their prolonged use is associated with a risk of serious, potentially persistent side-effects such as tardive dyskinesia. In this surgery, the use of a multilayered closure technique is very important to avoid the recurrence of CSF leakage. 25 mg/kg/day AND equivalents) and AND at dose levels of 5 and 25 mg/kg/day significantly decreased CYP2C11 activity. The AASS induced aggregation of the two leukocyte subpopulations was inhibited by the presence of bovine serum albumin (BSA) in the incubation media and by calcium exogenously added. Certain cultivars of some crops, including durum wheat (Triticum durum Desf.), have a propensity to accumulate cadmium in the grain.

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Identification and Susceptibility Profile of Candida fermentati from a worldwide collection of Candida guilliermondii clinical isolates. Gas-chromatographic study of the fatty acids in the blood of dermatologic patients. Emphasis is made on the impact of protein-energy malnutrition as well as on some specific deficiencies, particularly iron and folic acid. However, subcutaneous fat cells exhibited higher rates of basal lipolysis than omental fat cells and these differences were maintained when lipolysis was stimulated with theophylline. Comparative study of the clastogenic efficiency of ethyl methanesulfonate and diethyl sulfate in Drosophila melanogaster mature sperm. Controlling passive smoking through legislation in Ireland: an attack on civil liberty or good public can you overdose on periactin health policy?. The great plasticity of endosomes at this stage of maturation was also evident by electron microscopy.

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Changes in the mineral content of bones in fibrous osteodystrophy in standard minks and Arctic foxes. If the slit walls are identical, the density profiles at low temperatures or at high average densities rhoav of the fluid molecules in the slit have a sharp maximum in the middle of the slit, the value of the density at maximum being comparable to that of a liquid. Efficient antibiotic therapy in radical surgery on the maxillary sinus. These deterrent bryostatins represent the first example from the marine environment of a microbial symbiont producing an antipredator defense for its host. In the beta-TCP group, degradation began at 4 weeks and this degradation had increased just slightly after 8 weeks. To determine if the difference in 5-HT release between lean and obese rats might be due to differences in these neuromodulatory pathways, we examined the effects of phenylephrine (PE) and 5-HT on serotonergic DRN neurons using current-clamp recording. Our findings show that serum total and free testosterone levels in patients with prostate cancer are altered, supporting the possibility that prostate cancer may inhibit serum testosterone levels.

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The contemporary rise in the number of elective procedures performed in same-day surgery (SDS) requires that health care professionals increase their knowledge of patient satisfaction and recovery, including patient-assessed quality of life. Data included cause of death, demographics, location of the event, prior known illnesses, as well as psychiatric comorbidities. In contrast, the latencies of late cognitive components (N2b and P300, whose peak latencies were longer than 250 msec) and reaction times were significantly increased as target discriminability decreased. Replication of bacterial chromosomes increases copy numbers of genes located near origins of replication relative to genes located near termini. Extracytoplasmic function sigma factors regulate expression of the Bacillus subtilis yabE gene via a cis-acting antisense RNA. Due to the complexity of the process, the investigation of the constituent profile during fermentation is difficult.

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The objective of this study is to evaluate current means of monitoring of pregnant women victims of abdominal trauma and to determine whether systematic hospitalization is warranted. We developed an algorithm to classify five stages (Awake, Light, Hi Deep, Lo Deep and rapid eye movement (REM)) using a Hidden Markov Model (HMM), model fitting with the expectation-maximization (EM) algorithm, and estimation of the most likely sleep state sequence by the Viterbi algorithm. However, our confidence in the deeply branching position of diplomonads and parabasalids among eukaryotes is weakened by conflicting phylogenies and potential sources of artifact. Optimizing the management of renal anemia: challenges and new opportunities. As a result, we demonstrate that in complex mixtures of fluorophores, the relative concentration information is encoded in the fluorescence lifetime across multiple spectral bands.

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Two mechanisms for the increased firing rate appeared to be a reduction in the slow component of the afterhyperpolarization (AHP) and a modest depolarization. Herein, we report that Autographa californica nucleopolyhedrovirus, a member of the Baculoviridae family, is capable of stimulating antiviral activity in mammalian cells. The effects of Hamaker constants of the materials forming the system, especially those of the two different adsorbed surfactant layers with uniform density (A(1) and A(2)), on the acticin van der Waals interaction were investigated. 2) Is there documented causality of serious, far-reaching, and irreversible clinical harm to the fetal or neonatal patient?. A common cellular mechanism leading to the production of these potent toxins remains elusive. Antibody-mediated rejection is the main cause of deterioration of kidney transplants and frequently is detected only by means of protocol biopsies. Moreover, in the presence of rearranged copies the estimates are not correct. Acid hydrolysis of 1,6-dihydro-4-amino-3-methyl-6-phenyl-1,2, 4-triazin-5(4H)-one (1,6-dihydrometamitron). Light chain promoter regions in rainbow trout Oncorhynchus mykiss: function of a classical and an atypical Ig promoter.

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Finally, these data underscore the vital roles of both KH and non-KH domain sequences in Scp160p. Paramedic and midwifery student exposure to workplace violence during clinical placements in Australia - A pilot study. Drug therapy of ventricular arrhythmias - a contemporary perspective. Computer modeling of airbag-induced ocular injury in pilots wearing night vision goggles. One-hundred and 1 infants or children were recruited into this study. Serum coating markedly decreased adhesion to all materials, and only minor differences among the studied materials were observed. In patients to whom cardiac surgery presents very high risk, an angioplasty of LMCA can be life-saving, with good long term effects. Two treated groups (U-63,557A and U-61,431F) developed glomerular thrombosis similar to untreated endotoxin rats.

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These nurse executives cost of propecia in australia will lead in a way that makes an invigorating impact on human service in health care environments and they will be dedicated to preparing the nursing leaders of tomorrow. The study population was subjects who were referred to orthopedic surgeons or rheumatologists and had no inflammatory arthritis or secondary OA. Nowadays, more and more wide-coverage lexical dictionaries are electronically available in the public domain. The right salpingo-oophorectomy was performed and pathological diagnosis was mucinous ovarian adenocarcinoma. However, it should be remembered that the proportion of persons with this side effect is much reduced when the correct dosage is used, and the sliding scale of dosage starts with sufficiently low doses. The hypothesis tested was that neither of the surface treatments would produce higher bond strength of the adhesive luting agent to CAD-CAM ceramic. The purpose of this study was to assess whether reported echocardiographic indices and additional measurements were associated with operative strategy in right-dominant AVSD. The ultrastructural alterations of the nasal mucosa have been graded on the basis of their severity. The use of the QLQ-C30 and QLQ-PAN26 will provide a comprehensive system of QoL assessment in international trials of pancreatic cancer.

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