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Avapro

Avapro is an angiotensin II receptor blocker (sometimes called an ARB). Avapro is used to treat high blood pressure (hypertension) in adults and children at least 6 years old. Lowering blood pressure may lower your risk of a stroke or heart attack. Avapro is also used to treat kidney problems caused by type 2 diabetes.

Other names for this medication:
Aprovel, Irbecard, Irbesartan, Irbesartana, Irbesartanum, Irbest, Irovel

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Also known as: Irbesartan

Description

{name} (irbesartan) is an angiotensin II receptor blocker (sometimes called an ARB). Irbesartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

{name} is used to treat high blood pressure (hypertension) in adults and children at least 6 years old. Lowering blood pressure may lower your risk of a stroke or heart attack.

{name} is also used to treat kidney problems caused by type 2 diabetes.

Dosage

Usual Adult Dose for Hypertension:

Initial dose: 150 mg orally once a day Maximum dose: 300 mg orally once a day

Usual Adult Dose for Diabetic Nephropathy:

Target maintenance dose: 300 mg orally once a day

Use: Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (greater than 300 mg/day) in patients with type 2 diabetes and hypertension.

Detailed Avapro dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include fast heartbeats or fainting.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Avapro are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Avapro if you are allergic to irbesartan.

If you have diabetes, do not take Avapro with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking Avapro with aliskiren if you have kidney disease.

To make sure Avapro is safe for you, tell your doctor if you have:

a heart condition other than one being treated with irbesartan; kidney disease (or if you are on dialysis); or if you are on a low-salt diet.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Irbesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

If you plan to get pregnant, ask your doctor for a safer medicine to use before and during pregnancy. Having high blood pressure during pregnancy may cause complications in the mother and the baby.

You should not breastfeed while using this medicine.

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Resulting genotypes were analyzed for chromosomal changes, specifically copy number variation and absence of heterozygosity. One-day workshop-based training improves physical activity prescription knowledge in Latin American physicians: a pre-test post-test study. Clinical symptoms were assessed at pre-treatment, 3 months and 7 months. The goal of the case studies is to continue to develop a methodology that incorporates PBPK modeling to assess the likelihood that a chemical or class of chemicals may present an age- or gender-specific risk. Histogenetic pleiotropism in the crooked neck dwarf chick embryo: degeneration of the trachea and thymus. Strain 94-EI-185-2 produced iritis but only mild corneal changes.

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Simultaneous measurement of seminal L-carnitine, alpha,1-4-glucosidase, and glycerylphosphorylcholine in azoospermic and oligozoospermic patients. We sought to assess the effects on cerebrovascular events of treating patients with stable coronary disease with low-density lipoprotein cholesterol (LDL-C) levels substantially below 100 mg/dl. AQP2 expression levels were significantly augmented in the glucocorticoid-deficient rats compared with the controls under both basal and water-loaded conditions. These supramolecular structures in binary and ternary systems were investigated by small-and-wide-angle X-ray and neutron scattering, dynamic light scattering and conductivity measurements (in the presence of small amounts of salt). The mechanism for induction of dysmorphogenesis in experimental diabetic pregnancy has been shown to include deficiency states of membrane lipids (myoinositol, arachidonic acid, etc.), alteration in the prostaglandin cascade, and the generation of excess free oxygen radicals. A case of multiple myeloma causing profuse bleeding during a maximum dose of pepcid per day minor dental surgical procedure is presented. Based on structural and physiological evidence, it has been proposed that a glutamate residue on the extracellular end of the selectivity filter acts as a fast gate. These results suggest that dosages of pralidoxime should be adjusted in organophosphate-poisoned humans with renal failure when using high dosage regimen of pralidoxime.

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Randomly selected 4 large neonatal intensive care units in Thailand. Peptides 285-300 hFSHR, 216-235 hFSHR, 184-195 hFSHR, 79-89 hFSHR and 15-31 hFSHR were observed to inhibit FSH-induced cAMP production paxil 60 mg daily . Genomic DNA of 107 patients with esophageal cancer that underwent complete surgical resection between 1997 and 2005 was extracted. When relatives anchor on the premorbid personality, the perceived discontinuity of emotional reactions to stimuli triggering an emotional response in contrast to their own expectations gives rise to an extremely ambiguous situation. Physical control on CCl4 and CHCl3 desorption from artificially contaminated and aged sediments with supercritical carbon dioxide.

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Endothelin converting enzyme is the key enzyme in the generation of endothelin-1 from big-endothelin-1. Continuous glucose monitoring using the glucose sensor CGMS in metabolically normal pregnant women during betamethasone therapy for fetal respiratory distress syndrome. Statistical study of eight years on the etiology of infantile gastroenteritis. Strategies and partnerships toward prevention of Healthcare-Associated Venous Thromboembolism. This paper focuses on the organizational position and relations of hospitals within public sector health services.

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Improving quality of care through payment for performance: examining effects on the availability and stock-out of essential medical commodities in Tanzania. The application of phylogenetic inference methods, to data for a set of independent genes sampled randomly throughout the genome, often results in substantial incongruence in the single-gene phylogenetic estimates. Phenotypic variation of pigmentation according to growth temperature was then analyzed in DD and LL male and female flies, and in reciprocal F1. In 1 case epithelial membrane antigen (EMA) was negative, whereas in the second case focal expression of EMA by neoplastic cells was seen. Thus, more efficient RNA replication could cause faster cell growth, leading to the emergence of Darwinian evolution at the cellular level. Learning-dependent structural plasticity in the adult olfactory pathway.

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Prevalence of ocular surface symptoms, signs, and uncomfortable hours of wear in contact lens wearers: the effect of refitting with daily-wear silicone hydrogel lenses (senofilcon a). Both SEM approaches identified two items with gender-related bias and two items with age-related bias in the Anxiety subscale, and four items with age-related bias in the Depression subscale. Era is an essential G-protein in Escherichia coli identified originally as a homologue protein to Ras (E. On day 7 following the learning session a memory retention test was performed. Topical treatment of interdigital tinea pedis: terbinafine compared with clotrimazole. These cDNA clones were used as probes to screen mouse genomic libraries, and cosmid clones containing both NF-L and NF-M sequences were isolated as well as overlapping cosmids containing the NF-H gene. Photochromic Properties of 3-Deoxyanthocyanidin Pigments in Nontoxic Solvents. AngII-induced the expression of inflammatory cytokines in adult rat hypertrophied cardiomyocytes is mediated mainly by AT2, not by AT1 receptors. Pregnancy outcome of female survivors of childhood cancer: a report from the Childhood Cancer Survivor Study.

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