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Axedol (Tramadol)
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Axedol

Axedol is an opioid (narcotic) pain reliever. It works by binding to mu-opiate receptors in the brain and changes how you feel and respond to pain. Axedol is usually started at 25 mg per day. After slowly raising the dose over several days, a typical dose would be 50 to 100 mg by mouth every 4 to 6 hours as needed for pain.

Other names for this medication:
Accupain, Acuvin, Anatram, Atdol, Bestodol, Bramadol, Cadol, Contramal, Cosdol, Dolotram, Domaspas, Jpdol, Lagesic, Midol, Nictram, Opigesic, Relidol, Tramacip, Tramagesic, Tramex, Trampar, Trandol, Transic, Trasic, Ultracon, Ultrazac, Unidol, Urgendol, Veeradol, Zotadol

Similar Products:
Nimotop, Risperdal, Ultram, Seroquel, Diovan, Epivir

Also known as: Tramadol

Description

{name} (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

{name} is used to treat moderate to severe pain in adults.

The extended-release form of tramadol ({name} ER) is for around-the-clock treatment of pain. {name} ER is not for use on an as-needed basis for pain.

Dosage

Follow the directions on your prescription label and read all medication guides. Never use Axedol ER in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of Axedol ER.

Never share Axedol ER with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.

Stop taking all other opioid medications when you start taking Axedol ER.

Axedol ER can be taken with or without food, but take it the same way each time.

Swallow the capsule or tablet whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, break, open, or dissolve.

Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Never crush or break a Axedol ER pill to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death.

You may have withdrawal symptoms if you stop using Axedol ER suddenly. Ask your doctor before stopping the medicine.

Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Do not keep leftover Axedol ER. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash.

Detailed Axedol ER dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.

Storage

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Axedol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how Axedol ER will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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Cyclosporine (CsA) was previously reported to effectively suppress the induction of experimental autoimmune uveoretinitis (EAU) in rats immunized with S-antigen. The effect of previous exposure to dietary microbial phytase on the endogenous excretions of energy, nitrogen and minerals from turkeys. The production of human leukocyte interferon in a serum-free medium. One function of bone in organism is to mechanically support the body. Hepatic inflow occlusion can be safely employed in a continuous manner for approximately 1 hour, even during resection of chronically diseased liver, particularly when the liver is cooled below 30 degrees C prior to hepatic clamping by our simple in-situ hypothermia technique. Clinical application of genetic testing for posterior uveal melanoma.

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In silico structural analysis of quorum sensing genes inVibriofischeri. In spite of considerable individual differences, the greatest decrease in body weight occurred in mice receiving vitamins E and B complex. Functional parameters and 99mtechnetium-dimercaptosuccinic acid scan in acute pyelonephritis. Modulated fibronectin anchorage at polymer substrates controls angiogenesis. By immunofluorescence and by expressing a green fluorescent (GFP) chimera of cyclin B, we find that cyclin B is present in aggregates in the cytoplasm of immature oocytes. Discovering the full spectrum of cardiovascular disease: Minority Health Summit 2003: executive summary. The practice of group psychotherapy with adult insulin-dependent diabetics. The mutant plants exhibited relatively normal vascular patterning in leaves and cotyledons.

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Recognition of self-pollen during the self-incompatibility response in Brassica oleracea is mediated by the binding of a secreted peptide (the S locus cysteine-rich protein) to the S locus receptor kinase (SRK), a member of the plant receptor kinase (PRK) superfamily. Given such intriguing features, we have analyzed the long-term evolutionary pattern of the H1 multigene family through the evaluation of the relative importance of gene conversion, point mutation, and selection in generating and maintaining the different H1 subtypes. This was a cross-sectional study of 21 children aged 5-10 yr in a clinical research setting. Transgenic analysis of scleroderma: understanding key pathogenic events in vivo. A comparison of photolyase activity in three Australian tree frogs. C3v symmetric receptors show high selectivity and high affinity for phosphate. In contrast, TLR5 and TLR9 mRNA levels were significantly higher in IgAVN patients than in IgAN patients. An Unusual Case of Paraganglioma of the Broad Ligament Presenting as Cystic Mass. Membrane proteins were analyzed by electrophoresis in acrylamide gels containing sodium dodecyl sulfate.

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Forty consecutive patients with portal hypertension and 43 patients with non-ulcer dyspepsia (controls) underwent push enteroscopy and jejunal, duodenal and gastric biopsies. Our findings provide the first insight into the Kac events of B. Large seed size is a trait associated with plant species of mature, closed habitats, and is thought to supply an ample nutrient reserve necessary for seedling establishment. A deduced amino acid sequence of the protein was very similar to that of several other Y-box proteins, and we termed the protein rBYB1 (rat brain Y-box protein 1). These methods allow for the characterization of short-term kinetic responses and can be modified for the analysis of roots and seedlings from other species. Optimization of the cryopreservation of dromedary camel semen: Cryoprotectants and their concentration and equilibration times. If distant disease is found, certain sites, such as the CNS or long bones, may warrant aggressive therapy because failure to treat these sites may lead to excessive morbidity. Human immune responses to porcine endogenous retrovirus-derived peptides presented naturally in the context of porcine and human major histocompatibility complex class I molecules: implications in xenotransplantation of porcine organs. A simple model for the mammalian circulatory system is built in entirely physiological terms consisting of a ring shaped, one-dimensional tube which corresponds to the arterial, venular, and pulmonary trees, successively. Constraint based methods, such as Flux Balance Analysis (FBA) and Thermodynamics-based flux analysis (TFA), are commonly used to estimate the flow of metabolites through genome-wide metabolic networks, making it possible to identify the ranges of flux values that are consistent with the studied physiological and thermodynamic conditions.

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The syndrome of hypertension, hyperreninemia and secondary aldosteronism associated with renal juxtaglomerular cell tumor (primary reninism). Co-administration of an equi-molar CNDP with some fluorinated pyrimidine preparations potentiated their antitumor activity. Nevertheless, a direct, quantitative effect of acute smoking on exercise heat tolerance has not been reported. In vivo inhibition of CYP3A-mediated midazolam metabolism by anchusan in rats. Viral-specific protein synthesis in UV light-irradiated, nonsuppressing Bacillus subtilis 60084 was analyzed with exponential acrylamide gels.

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Our results should furthermore be useful to build up an analytic expression for the index of refraction of chromium forsterite. Metabolism of arachidonic acid results in a host of biologically active compounds with profound effects on airway inflammation (1). Since there is no difference in the level of acetylated histone H4 between the intestinal-type and diffuse-type of gastric cancer, histone H4 deacetylation may be involved in both types of gastric cancer. Results indicated that CVIT consists of two major subspecialties: one corresponding to cardiac procedures and one corresponding to procedures involving organ systems other than the heart. Iterative learning-based decentralized adaptive tracker for large-scale systems: a digital redesign approach. A contralateral stenosis is a risk factor for CEA from the hemodynamical point of view, and extreme care should be taken when performing CEA in patients with bilateral stenoses. Seasonal and circadian exacerbations of ischemic heart disease and their prognosis under the regional conditions of Tashkent. On-line sheathless capillary electrophoresis/nanoelectrospray ionization-tandem mass spectrometry for the analysis of glycosaminoglycan oligosaccharides. Anterior gastropexy may reduce the recurrence rate after laparoscopic paraesophageal hernia repair. Thus, such HIV/HBsAg hybrid particles could be a new approach to multivalent vaccination.

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The management of the older lymphoma patient with cytotoxic chemotherapy requires knowledge of the pharmacologic effects of age and awareness of the diversity of the older population. There was reduced pin-prick hyperalgesia and touch allodynia in the EPI group. This review article provides an epidemiologic overview of these diseases, focussing on recent German data. Cell-mediated immunity to Varicella-Zoster antigen in acute Herpes zoster (shingles). The clinical and radiological findings were suggestive for primary malignant lesion. The emergence and spread of multidrug-resistant (MDR) Gram negative bacteria presents a serious threat for public health. Two-dimensional pressure-driven nanorod-to-nanowire reactions in Langmuir monolayers at room temperature. Vitamin K2 inhibits the growth and invasiveness of hepatocellular carcinoma cells via protein kinase A activation. Drug-drug interaction (DDI) is referred as the changes of physical and chemical properties, as well as the pharmacokinetics or pharmacodynamics of drugs administered simultaneously or consecutively.

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The phosphatidylglycerol lipid was deuterated at all three segments of the glycerol headgroup. One such strong RMA derivative of FK-506 (SDZ neurontin gabapentin 300 mg obat apa 280-629) was further shown able to restore completely daunomycin retention by highly resistant MDR P388 tumor cells. All proband groups showed significantly increased brain signal randomness in dorsal and ventral prefrontal cortex (PFC), and unaffected relatives showed no complexity differences in PFC regions. Difference in size (temporal separation) was important to the co-existence of I. In this model the D1/D2 agonist apomorphine, the D1 agonist 2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine hydrochloride and the D2 agonists N-n-propyl-N-phenylethyl-P-(3-hydroxyphenyl) ethylamine hydrochloride, trans-(-)-4aR,4,4a,5,6,7,8,8a,9-octahydro-5-propyl-1H-pyrazolo-(3, 4-g) quinolino monohydrochloride and lisuride evoked a characteristic spectrum of motor responses when administered systemically. Pathological changes based on degeneration of epithelial structures predominantly with preserved typical cell differentiation, but with unstable epithelial secretory function were detected in biopsy specimens of gastroduodenal mucosa from patients with psoriasis associated with chronic opisthorchiasis. Electrolytic lesion or pharmacological inactivation of the ipsilateral A5 neurons altered both the phrenic burst frequency and occurrence after the stimulation. The spinal reflex potential was recorded from the L5 ventral root following stimulation of the L5 dorsal root, and the effects of electrical stimulation of the LC and the NRM were tested in anesthetized rats. Progressive increase in striatal dopamine synthesis capacity as patients develop psychosis: a PET study. Percutaneous transluminal coronary angioplasty: an evaluation of sustained clinical efficacy.

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The present study investigated the effects of reducing serotonin function, using acute tryptophan depletion, on the recognition of basic facial expressions of emotions in healthy male and female volunteers. The results of clinical treatment of a non-typical and specific skin disease are presented. Insulin resistance, fibrosis, and genotype are independent predictors of the response to antiviral therapy in chronic hepatitis C patients treated with peginterferon plus ribavirin. These results are congruent with a conceptualization of adolescent MDD and adult MDD as having very similar etiologic determinants. The incidence of this subset of CSCC continues to rise in the US, as does the confusion surrounding exactly how it should be managed.

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Automated affinity chromatography measurements of compound mixtures using a lab-on-valve apparatus coupled to electrospray ionization mass spectrometry. To improve our understanding of this tumor and define outcomes with current management, we performed a retrospective review of these cases. Serial assays of thyroid and pituitary hormones were done, and magnetic resonance imaging of the pituitary was performed before and 16 weeks after initiation of cabergoline therapy. Uncoupling of oxidative phosphorylation and Smac/DIABLO release are not sufficient to account for induction of apoptosis by sulindac sulfide in human colorectal cancer cells. Within community programs, presence of a relevant goal was positively related to change in independent living skills, and clients with musculoskeletal impairments tended to regress in motor and eating skills. Symptoms of the antiphospholipid syndrome determined the outcome.

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These results were further synthesized with the relational cultural theory (RCT). Early onset (less than 25 years of age) was associated with a high frequency of A1, B17, B37, and Cw6 antigens, whereas patients with late onset (greater than 25 years of age) had a significantly lower incidence of A1, B17, and Cw6, which did not differ from that of the control subjects. We report four children from four inbred Arab families with varying manifestations of max dose of klonopin per day Hennekam syndrome and additional features that have not been previously reported. Nevertheless, moderate levels of sodium chloride improved bacteriocin activity because they increased the biomass concentration at which bacteriocin production was switched off. Greater efforts are warranted to prevent injuries associated with other nursery products, especially baby carriers, cribs, and strollers. Adherent omentum was reduced from the sac and a wide flap of peritoneum extending 5 cm on all sides of the fascial defect was raised. In addition, we present the result of a simulation comparing our methods to well-known statistics and multiple testing adjustments.

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Moreover, the N -phenylacetyl and N - iso- butanoyl derivatives mainly induced IgG responses that are desirable for antitumor applications. All but 1 involve female patients, all adolescents, most have alveolar histology and poor prognosis. Incubation with copper for different durations produced mildly, moderately, and highly oxidised LDL (having, respectively, ca. Nonhomologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in Schizosaccharomyces pombe. Socioeconomic disadvantage was strongly associated with poorer HIV treatment can i take zovirax while breastfeeding outcomes in this setting with universal health care. However, there is only limited experience with these methods in practice. Targeting adhesion signaling in KRAS, LKB1 mutant lung adenocarcinoma.

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Examples for investigating gene fusions and domain recombination using HOPS are given. Supra-ampullar cystectomy with detubularized ileal orthotopic neobladder allows to preserve sexual function in nearly all the cases and to maintain urinary continence in most patients, without compromising oncological outcome. The scaling properties of the soft-sphere potential allow the derivation of an exact expression for the pressure of a frozen liquid, i.e., the pressure corresponding to configurations which are local minima in its multidimensional potential energy landscape. We describe a case of NEH with an unusual presentation of annular plaques. All England smoking data by deprivation category obtained from the Health Survey of England were used to estimate neighbourhood smoking prevalence rates. Thus, though IL2 gene activation, synthesis or release apparently can be activated via at least two pathways: T cell receptor or Thy-1, it seems that activation of the genes responsible for synthesis and release of the helper factors, which ensure antigen-specific B cell proliferation and differentiation, needs Th cell-B contact mediated via the antigen-specific T cell receptor. In 2006, there were an estimated 3,672 arrests for CP possession, compared with 1,713 arrests in 2000. standard population, and age-specific rates and stage distributions were computed by anatomic subsite, race, and gender.

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A combination of physicochemical methods was applied including surface tension measurements on adsorbed and spread monolayers at the air-water interface, Fourier transform infrared, circular dichroism, and atomic force microscopy on Langmuir-Blodgett monolayers. Patients undergoing stent placement as treatment for severe stenosis of the internal carotid artery (ICA) were assessed with MR imaging in a combined MR-radiographic (XMR) angiography suite. The prevalence of BL in a Sicilian population of CRF patients was higher than in the general population, but lower than in patients with CRF on chronic HD. To gain clarity about the institutional changes necessary to limit the scale of economic activity, it is essential that ecological economics understands the limitations of its neoclassical roots and expands its theoretical framework to include how markets are embedded in social and institutional structures. The contrasting low versus high diversity in the two sub-populations (K1 and K2) infers that a combination of local transmission and cross-border malaria from higher transmission regions shape the genetic make-up of the P. The nuclear bile acid receptor FXR as a novel therapeutic target in cholestatic liver diseases: hype or hope?. Expression and regulation of Groucho-related genes in the embryonic chicken feather bud. In contrast MOR-IR was present only in supporting cells at P0-P16. Direct observation by cryoEM reveals that this occupancy-enhancing N-terminal domain is partially ordered. Phosphoketolases catalyze an energy- and redox-independent cleavage of certain sugar phosphates.

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Ultrastructure of Goussia cruciata (Apicomplexa: Coccidia) infecting the liver of horse mackerel, Trachurus trachurus (L.), from Ibero-Atlantic waters. Electrochemical detection of DNA hybridization using a change in flexibility. HIV may be one of the major causative agents of multiple benign giant esophageal ulcers in AIDS patients. Production and characterization of monoclonal antibodies to the extracellular domain of P0. Electromechanical Conditioning of Adult Progenitor Cells Improves Recovery of Cardiac Function After Myocardial Infarction. Pathologic findings, surgical approach, extent of tumor resection, rate of facial nerve mobilization and ear canal closure, facial and lower cranial nerve outcomes, and hearing preservation.

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