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Axepta (Atomoxetine)
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Axepta

Axepta is in a class of medications called selective norepinephrine reuptake inhibitors. It works by increasing the levels of norepinephrine, a natural substance in the brain that is needed to control behavior.

Other names for this medication:
Atomoxetine, Attentrol, Axepta, Tomoxetin

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Also known as: Atomoxetine

Description

Axepta is an FDA-approved medication taken for the treatment of attention deficit hyperactivity disorder (ADHD). Its active ingredient, Atomoxetine, is a selective norepinephrine reuptake inhibitor. Atomoxetine increases the balance of certain chemicals in the brain (e.g., norepinephrine), thereby decreasing impulsive behavior and hyperactivity. Axepta may affect the attention span and behavior of the person taking it. It is also known as Atomoxetine, Attentrol, Tomoxetin, Attentin, Axepta.

Dosage

Usual Adult Dose for Attention Deficit Disorder:

-Initial Dose: 40 mg/day orally. -Maintenance Dose: Increase dose to 80 mg/day orally after a minimum of 3 days at the initial dose. -Maximum Dose: After 2 to 4 additional weeks, the dose may be increased up to 100 mg/day in patients who have not achieved an optimal response. Comments: Take dose once a day in the morning OR as evenly divided doses in the morning and late afternoon/early evening. Use: Treatment of Attention Deficit Hyperactivity Disorder (ADHD).

Usual Pediatric Dose for Attention Deficit Disorder:

70 kg or Less: -Initial Dose: 0.5 mg/kg/day orally. -Maintenance dose: Increase dose to 1.2 mg/kg/day after a minimum of 3 days at the initial dose. -Maximum dose: 1.4 mg/kg/day or 100 mg/day, whichever is less. Over 70 kg: -Initial Dose: 40 mg/day orally. -Maintenance dose: Increase dose to 80 mg/day after a minimum of 3 days at the initial dose. -Maximum dose: After 2 to 4 additional weeks, the dose may be increased up to 100 mg/day in patients who have not achieved an optimal response. Comments: Take dose once a day in the morning OR as evenly divided doses in the morning and late afternoon/early evening. Use: Treatment of Attention Deficit Hyperactivity Disorder (ADHD) in pediatric patients age 6 and older.

Detailed Axepta dosage information

Overdose

If you overdose Generic Axepta and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medication after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Axepta are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not use Axepta if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

You should not use this medicine if you are allergic to atomoxetine, or if you have:

severe heart or blood vessel problems; narrow-angle glaucoma; or pheochromocytoma (tumor of the adrenal gland).

Axepta has caused stroke, heart attack, and sudden death in certain people. Tell your doctor if you have:

heart problems or a congenital heart defect; high blood pressure; or a family history of heart disease or sudden death.

To make sure this medicine is safe for you, tell your doctor if you or anyone in your family has ever had:

depression, mental illness, bipolar disorder, psychosis; suicidal thoughts or actions; low blood pressure; or liver disease.

Some young people have thoughts about suicide when first taking Axepta, or whenever the dose is changed. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant before taking Axepta.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of atomoxetine on the baby.

It may not be safe to breastfeed while using Axepta. Ask your doctor about any risk,

Axepta is not FDA-approved for use by anyone younger than 6 years old.

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We encountered a 74-year-old female in whom nonunion-induced implant rupture occurred after treatment of atypical subtrochanteric femoral fracture with internal fixation using a long femoral nail. The embryo ofSabellaria cementarium (Polychaeta) forms a polar lobe at each of the first two cleavage divisions which becomes absorbed into one of the blastomeres at the end of the division. Moreover, affine neural dynamial systems (A-NDSs) are provided as nontrivial examples of NDSs and it is proved that any DS can be finitely approximated by an A-NDS with any precision. Prospective, multicentre, longitudinal, observational cohort study with lymphoproliferative disorder (LPD) and non-small-cell lung cancer (NSCLC) patients, receiving first- or second-line (immuno-) CT (excluding myeloablative CT). The chlorophyll a/b ratio of LHCII obtained from 6-day-old control cotyledons and their absorption, chlorophyll a fluorescence emission and the circular dichroism (CD) spectral properties were comparable to the LHCII preparations from other plants such as pea and spinach. If adhesion formation is prevented by various methods, the integrity of ischemic bowel anastomosis may be compromised. Lymphocyte-endothelial interactions in inflamed synovia: involvement of several adhesion molecules and integrin epitopes. Hg has accumulated mainly in the litter (where its concentrations were the highest), and in the layer 0-10 cm. As controls, PBMC from both groups of donors were cultured in vitro for 7 days without antigen or were freshly isolated, and lysis of the K562 target was determined. We investigated a FV Leiden heterozygous patient who had received an allogeneic bone marrow transplant from a normal donor.

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Western values and culture have undermined concepts filial piety in Taiwan in recent decades. Results showed a wide variability in terminology, choice of structures contoured and in the size and shape of the contoured structures. Leaded eye cosmetics: a cultural cause of elevated lead levels in children. Diverging findings concerning the rate of postoperative wound infections in patients undergoing breast surgery have been reported, and little is known regarding the possible risk factors for these infections and their relative importance. Effects of interstate migration on the geographic distribution of stroke mortality in the United States. Differences in the pattern of macromolecules between vegetative and aggregation Competent Cells in Dictyostelium discoideum. However, when maintained long-term on a high-fat diet, the IAP-deficient mice showed faster body weight gain than did control animals. Culture of HEK293-EBNA1 Cells for Production of Recombinant Proteins. CT scan shows an important gastric dilatation associated with complete halt of the third part of the duodenum.

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Impact of seroconversion and antichlamydial treatment on the rate of pre-eclampsia among Egyptian primigravidae. Currently, the mostly used techniques are direct measurement of airflow on intubated animals and whole body plethysmography. Multiple system atrophy (MSA) is a devastating and fatal neurodegenerative disorder. The fraction of accessible surface occupied by mobile surface proteins can be accurately represented by including steric exclusion in the statistical thermodynamic analysis of the data. The mechanism of this reaction is suggested to involve coordination of a hydrated and an unhydrated substrate molecule through their carbon-1 bound oxygen atoms followed by a hydride shift from the hydrated to the unhydrated substrate. Orthodontic applications of a new visible light curing (VLC) resin system. In this review, recent studies of diffuse large B-cell lymphoma (DLBCL), primary mediastinal large B-cell lymphoma, mantle cell lymphoma (MCL), and follicular lymphoma are highlighted, and the impact of gene expression profiling on the molecular diagnosis of these diseases is discussed. However, it may be too early to see the full effect of adult exposures in this cohort. The problem faced by the Burmese group in Australia is distinctive and poignant.

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These results suggest that information about an opponent can influence the mechanisms underlying pressure-induced performance errors. This study is an examination of the interaction between Ac-SDKP and transforming growth factor-beta (TGF-beta), one of the key cytokines in the progression of renal disease, in human mesangial cells. We found an inverse association between IMT and IgM autoantibody titers to MDA-LDL that remained statistically significant after adjusting for age, gender, LDL cholesterol, systolic blood pressure, CRP, and smoking. Glutathione (GSH) plays a central role in maintenance of cellular redox homeostasis and protection against oxidative injury. The serum calcium level, alkaline phosphatase activity and calcitonin level were not significantly different between the experimental groups, but the PTH level of the serum in the UF-MCa diet group was significantly lower than that in the NP-MCa diet group. Overall, LTLE patients self-reported more cognitive difficulties across all domains. The study suggests that, despite the model error, the ground water model contributed positively to the design of the remediation system. The high degree of polymorphism observed in the human T cell receptor beta chain complex should allow exploration of possible associations between T cell receptor genes and inherited diseases involving the immune system. We also observed a decrease in the immunoreactivity of SP and CGRP, and an increase in their mRNA expression in the trigeminal ganglion neurons. Unexpected Photodegradation of a Phosphaketenyl-Substituted Germyliumylidene Borate Complex.

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The concept that antimutagenesis is a normal genetic process whose function is to ensure integrity and stability of hereditary structures has been formulated and substantiated. Selection of restorative materials must be based on knowledge of their wear behavior and the individual needs of each patient. The clinical manifestations of infection caused by Mycobacterium genavense are similar to those of infection caused by Mycobacterium avium complex organisms. IgA cold agglutinins recognize Pr and Sa antigens expressed on glycophorins. Hyperploidy increased significantly at a concentration of 40 nM nocodazole in mouse metaphase II oocytes, similar to thresholds inducing nondisjunction in cultured human lymphocytes. In general, porosity increases the risk of diseases as it makes the body organs vulnerable to external hot and cold weather. Divergence in physiological factors affecting swimming performance between anadromous and resident populations of brook charr Salvelinus fontinalis.

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We conducted an experiment in the western Great Basin to determine whether heteromyids perceive emerging seedlings of Indian ricegrass, Achnatherum hymenoides, as beacons to cache locations. Identifying factors associated with snakebite-related AKI might help clinicians to be aware of snakebite patients who are at risk of AKI, particularly patients who demonstrate renal tubular dysfunction after Viperidae bites. Men with a National Institutes of Health (NIH) diagnosis of CP/CPPS (specifically, no infection localized to the prostate) were randomized to levofloxacin (500 mg/day) or placebo for 6 weeks in 11 Canadian centers. A hypothesis explaining the time sequence of the carcinoid valve involvement is suggested. Laboratory examination revealed a high serum level of CA19-9 (155 U/ml). Treatment with buprofezin did not cause a detectable induction of DNA repair synthesis, an indicator of DNA damage, but significantly increased the frequency of micronuclei. A Mycobacterium avium PPE gene is associated with the ability of the bacterium to grow in macrophages and virulence in mice. Clinicians have few quantitative studies that rank the in vivo pulp capping effects of commonly used restorative materials.

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Archaeological finds provide a helpful source of information concerning women who performed medical activities other than midwifery, folk medicine and sorcery. We examined the signaling mechanisms involved in the differentiation-inducing activity of lupeol toward B16 2F2 melanoma cells. Germline mutations in LKB1, TSC2, or PTEN tumor suppressor genes result in hamartomatous syndromes with shared tumor biological features. A preliminary estimate of the radius of such a force field for the perylene tetracarboxylic diimide chromophore is about 90-120 A. In the short term, operation of patients with an unruptured aneurysm has a considerable impact on functional health and quality of life. Seven of 10 cases were categorized as Breast Imaging Reporting and Data System score of 4 or higher by all four readers when reviewing spectral images in combination with mammograms.

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Identification of a microtubule-based cytoplasmic motor in the nematode C. The role of various self-monitoring protocols and their impact on outcome is also explored. Transcriptional regulation by zinc-finger proteins Sp1 and MAZ involves interactions with the same cis-elements. Circumportal pancreas is a rare entity every pancreatic surgeon should be aware of. In cells stably transfected with plasmids of full-length alpha1A calcium channel cDNAs, the C-terminal fragment protein is present in the mutant transformant but not in the wild-type one, indicative that this C-terminal fragment with the expanded polyglutamine tract is more resistant to proteolysis than that with the normal sized polyglutamine tract. The upper incisor inclination and the lower incisor position were the most affected variables with age and gender. Cognitive performance was assessed by various clinician- and caregiver-rated measures. These include tumor location, presumed or known histology, and patient symptoms at time of diagnosis or evidence of progression either clinically or as demonstrated by neuroimaging.

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We show that the resulting deep regressor gradually and evenly approaches the true facial landmarks stage by stage, avoiding the tendency that often occurs in the cascaded regression methods and deteriorates the overall performance: yielding early stage regressors with high alignment accuracy gains but later stage regressors with low alignment accuracy gains. Electrostatic interaction between ion-penetrable membranes in a salt-free medium. The evolution of multiple myeloma (MM) depends on complex signals from the bone marrow (BM) microenvironment, supporting the proliferation and survival of malignant plasma cells. Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases. Modulation of host immunity has been observed in human immunodeficiency virus (HIV) infections. Properties of Epithelial Cells and Vaginal Secretions in Pregnant Women When Lactobacillus crispatus or Lactobacillus iners Dominate the Vaginal Microbiome. These results suggest that there may be no difference between the 2 approaches in terms of postoperative atrophy. argus with Lasius ants is consistent among populations, and occurs at several spatial scales. Radiotherapy for oral cancer as a risk factor for second primary cancers.

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Parathyroid carcinoma: location of pelvic metastases by parathyroid hormone assay. These proteins have an important role in cell growth, actin cytoskeleton organisation, membrane trafficking, gene expression, cell proliferation/migration and programmed cell death. Effect of the activation of macrophages on the course of regeneration of rat liver following partial hepatectomy. Microscopical examination of the masses revealed severe, chronic, locally extensive granulomatous or pyogranulomatous inflammation with intralesional spherules consistent with Coccidioides spp. Distribution of potassium levels on admission for CPR--severe hypokalaemia with dysmorphophobic eating disorders. To test this hypothesis, we examined the fine structure of the NM in synchronous populations of G1 Chinese hamster ovary cells before and after heating by using the technique of resinless section electron microscopy. Therefore, since its safety profile is clinically acceptable, this adjuvanted vaccine represents an excellent option for influenza immunization of elderly subjects at highest risk of complications. A plate method for rapid screening of Ketogulonicigenium vulgare mutants for enhanced 2-keto-l-gulonic acid production. We have observed a significant increase in the concentrations of lead, cadmium and arsenic in blood and urine of persons from control group who smoked 20 or over 20 cigarettes a day in comparison to the non-smoking persons from control group, which suggest, that tobacco smoking increase the heavy metals concentrations in the organisms.

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