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Azithrex (Azithromycin)
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Azithrex

Azithrex is an antibiotic used to treat various types of bacterial infections of the respiratory tract, ear, nose, throat, lungs, skin, and eye in adults and children. It is also effective in typhoid fever and some sexually transmitted diseases like gonorrhea.

Other names for this medication:
Amovin, Azimed, Azithral, Azitrolit, Azitropharma, Aziwok, Azomax, Azomex, Azyter, Doromax, Goxil, Ilozin, Kromicin, Macrozit, Magnabiotic, Misultina, Neofarmiz, Odazyth, Orobiotic, Phagocin, Tanezox, Texis, Thiza, Tridosil, Zedd, Zibac, Zinfect, Zithromac, Zitrim, Zitrocin, Zitrotek, Zival, Zycin

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Also known as: Azithromycin

Description

Azithrex (Azithrex tablets and Azithrex for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Azithrex has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Azithrex is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Azithrex, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Azithrex is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Azithrex for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.

Dosage

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Azithrex Z-Pak oral is taken by mouth. This medicine injection is given as an infusion into a vein, usually for 2 days before you switch to this medicine oral. A healthcare provider will give you this injection.

You may take Azithrex Z-Pak oral with or without food.

Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Use Azithrex Z-Pak for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Azithrex Z-Pak will not treat a viral infection such as the flu or a common cold.

Store at room temperature away from moisture and heat. Throw away any unused liquid medicine after 10 days.

Detailed Azithrex dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not refrigerate or freeze the extended-release oral liquid. After water has been added to the powder, use the dose within 12 hours and throw away any unused liquid after your dose.

You may store the oral liquid at room temperature or in the refrigerator. Do not freeze the bottle. Do not keep the oral liquid for more than 10 days. Throw away any unused liquid after all doses are completed.

Side effects

The most common side effects associated with Azithrex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of azithromycin injection in the elderly. However, elderly patients are more likely to have age-related heart problems, which may require caution in patients receiving azithromycin injection.

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Only a small number of patients with thionamide-induced agranulocytosis have had G-CSF treatment, and most outcomes have generally supported a beneficial effect. Study was conducted to investigate the effects of (i) carbimazole and (ii) simultaneous administration of thyroxine (thyroid hormone analogue) on the morphology of rat adrenals. COX-2 inhibitors have a promising role in the prevention and treatment of gastric cancer. The electrocardiograms of 27 transmission-line workers and 26 male volunteers were recorded with a Holter recorder both in and outside the fields. From this body of work we highlight results from three candidate genes, REELIN (RELN), SEROTONIN TRANSPORTER (5HTT), and ENGRAILED 2 (EN2) and discuss the relevant neuroscience, molecular genetics, and statistical results that suggest involvement of these genes in autism susceptibility. Plasma membrane repair is an essential process for maintenance of homeostasis at the cellular and tissue levels, whereas compromised repair capacity contributes to degenerative human diseases. These results confirm that H cows have poorer first-service conception rates than L cows, but do not support an hypothesis that there are major differences between these strains of Holstein-Friesian dairy cows in the rate of restoration in the hypothalamo-pituitary axis. First-line gemcitabine with cisplatin or epirubicin in advanced non-small-cell lung cancer: a phase III trial.

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Role of phosphatidylserine binding in tissue distribution of amine-containing basic compounds. These results suggest a non-genomic mode of transmission of the impact of early stress in mice. First, orthology detection becomes impractical and unreliable when too many species are included. Evidence for a noradrenergic projection to the subcommissural organ. IgE of these patients has been shown to bind endochitinases containing an N-terminal hevein-like domain (HLD). We report on a two-day consultative meeting in 2010 on developing international collaboration for the fight against HIV/AIDS between Cameroonian and USA nursing students.

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These interesting preliminary results warrant further investigation to disentangle the genetic role of ACE on hydration homeostasis. Atazanavir (ATV) not boosted by ritonavir (uATV) has been frequently used in the past for switching combination antiretroviral therapy (cART). A population-based case-control study was undertaken and 36 adolescents with autism were pairwise matched for age and IQ to 36 adolescents without autism. (3) To compare the antifungal effect of triphala churna and chlorhexidine gluconate with a control. Gallbladder stone is one of the major cause of morbidity in adults. of chlorobis(isopropyl)phosphine afforded chloro-substituted silafluorene 4. Interaction of cyproterone acetate with rat prostatic androgen receptors.

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Cryoprotection mechanisms of polyethylene glycols on lactate dehydrogenase during freeze-thawing. These data demonstrate that FHOD1 interacts with and regulates the structure of the cytoskeleton and stimulates cell migration in an integrin-independent manner. We report the case of a 7-year-old girl with bilateral knee stiffness, marked anterior bowing of both legs, and inability to walk without aid. The availability of several techniques of valve implantation in the group of non-surgical patients with severe AS potentially broadens the patient population with indications for this treatment. The main protein complexes that play a role in mRNA export are described. Left hepatic lobectomy was performed, and a tumor was found that measured 8.0 x 7.0 x 6.0 cm. The transport of proteins between the endoplasmic reticulum (ER) and the Golgi apparatus in plants is an exciting and constantly expanding topic, which has attracted much attention in recent years. On the other hand it has become possible to manipulate the organization of polyelectrolytes at interfaces via lipid charge density and ionic strength. Yeast transcription factor TFIIH (also known as factor b) is a component of the RNA polymerase II initiation complex. Visualization of the metaphase II meiotic spindle in living human oocytes using the Polscope enables the prediction of embryonic developmental competence after ICSI.

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In this study, we used the transposon sequencing (Tn-Seq) technique, which combines transposon mutagenesis with massive parallel sequencing, to study the in vivo fitness of a pool of Leptospira interrogans mutants. TNF binds to two receptors on the outer membranes of most human cell lines. Colony-stimulating factors (CSFs) are glycoprotein growth factors that influence the proliferation and differentiation of hematopoietic progenitor cells. Neuropathologic analysis showed unusual changes including severe neuronal loss in the inferior olive and the dentate nucleus, and absence of obvious lesions in the thalamus. The GTG-banding patterns and ideograms of two canid species, the domestic dog and the silver fox, are presented and compared. We identified 233 strains that had an altered growth rate relative to wild type, of which 107 showed increased resistance to APAP and 126 showed increased sensitivity.

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