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Bazuctril (Roxithromycin)
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Bazuctril

Bazuctril is a semi-synthetic macrolide antibiotic. It is a white crystalline powder. Bazuctril is very slightly soluble in water, freely soluble in acetone, in alcohol and in methylene chloride. It is slightly soluble in dilute hydrochloric acid.

Other names for this medication:
Acevor, Aristomycin, Assoral, Azuril, Bazuctril, Biaxsig, Crolix, Delos, Dorolid, Elrox, Erybros, Ladlid, Makrodex, Monobac, Odonticina, Overal, Pedrox, Ritosin, Rokithrid, Roksolit, Rolicyn, Rolid, Romac, Rotramin, Roxacine

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Also known as: Roxithromycin

Description

Generic Bazuctril belongs to macrolides group of antibiotics which are prescribed for treating serious bacterial infections such as acute pharyngitis (sore throat and discomfort when swallowing), tonsillitis, sinusitis, acute bronchitis (infection of the bronchi causing coughing), pneumonia (lung infection characterised by fever, malaise, headache), skin and soft tissue infections, non gonoccocal urethritis, impetigo (bacterial infection causing sores on the skin). It acts on the bacteria which causes the above mention bacterial infections caused by the bacteria. It kills completely or slows the growth of these sensitive bacteria in our body. Generic name of Generic Bazuctril is Roxithromycin. Bazuctril is also known as Roxithromycin, Roximycin, Biaxsig, Roxar, Surlid. Brand name of Generic Bazuctril is Bazuctril.

Dosage

Bazuctril is typically prescribed for a period of 7 to 14 days and patients should take the medication for as long as it has been prescribed to prevent the infection from returning even if they become asymptomatic. Patients should not however, take doses larger than has been prescribed as this can result in an overdose. Overdosing requires immediate medical intervention and may present with symptoms which include abdominal pain, nausea, diarrhea, vomiting, and a general and prolonged feeling of illness.

Overdose

Immediately telephone your doctor or pharmacist. Do this even if there are no signs of discomfort or poisoning.

Storage

Keep the tablets in the foil until it is time to take them.

Keep the tablets/in a cool dry place where the temperature stays below 30 degrees C.

Do not store Bazuctril or any other medicine in the bathroom or near a sink.

Do not leave it in the car on hot days or on window sills.

Heat and dampness can destroy some medicines.

Keep it where children cannot reach it.

A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Side effects

The most common side effects associated with Bazuctril are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

The safety of roxithromycin has not been demonstrated in patients with impaired hepatic or renal function. Caution should be exercised if roxithromycin is administered to patients with impaired hepatic or renal function. If administered to patients with severe impaired hepatic function (eg. hepatic cirrhosis with jaundice and/or ascites), consideration should be given to reducing the daily dosage to half the usual dosage.

Prolonged or repeated use of antibiotics including roxithromycin may result in superinfection by resistant organisms. In the event of superinfection, roxithromycin should be discontinued and appropriate therapy instituted.

When indicated, incision, drainage or other appropriate surgical procedures should be performed in conjunction with antibiotic therapy.

Antibiotic associated pseudomembranous colitis has been reported with many antibiotics. A toxin produced by Clostridium difficile appears to be the primary cause. The severity of the colitis may range from mild to life threatening. It is important to consider this diagnosis in patients who develop diarrhoea or colitis in association with antibiotic use (this may occur up to several weeks after cessation of antibiotic therapy). Mild cases usually respond to drug discontinuation alone. However, in moderate to severe cases, appropriate therapy with a suitable oral antibacterial agent effective against Clostridium difficile should be considered. Fluids, electrolytes and protein replacement therapy should be provided when indicated.

Roxithromycin, like erythromycin, has been shown in vitro to elicit a concentration - dependent lengthening in cardiac action potential duration. Such an effect is manifested only at supra – therapeutic concentrations. Accordingly, the recommended doses should not be exceeded. In certain conditions macrolides, including roxithromycin, have the potential to prolong the QT interval. Therefore roxithromycin should be used with caution in patients with congenital prolongation of the QT interval, with ongoing proarrhythmic conditions (ie uncorrected hypokalemia or hypomagnesaemia, clinically significant bradycardia), and in patients receiving Class IA and III antiarrhythmic agents.

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OCULAR COMPLICATIONS CAUSED BY Cryptococcus gattii AFLP4/VGI MENINGITIS IN AN IMMUNOCOMPETENT HOST. Two estimators are formulated: one using a dynamic neural network and another using a linear estimator. Reasons that influence the efficacy of cervical cancer screening are failure to screen all women at risk, as well as inherent technical limitations of the conventional cervical smear. Bigger partial patterns from anterior fragments may have any belt up to no. My colleagues and I have investigated this question in four models.

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Macroscopic cartilage formation with embryonic stem-cell-derived vantin antibiotic and alcohol mesodermal progenitor cells. Imidazol-2-ylidenes, a family of N-heterocyclic carbenes (NHC), are efficient catalysts in the transesterification involving numerous esters and alcohols. The expression of ER-alpha, but not of ER-beta, in menopausal SI women was regulated by estrogen/progestin replacement therapy. The Cochrane Controlled Trials Register was last searched in 1999 (Cochrane Library Issue 4, 1999). The performance of the algorithm is tested based on simulated data. Tumor physiology could potentially be used to optimize the sequence of neoadjuvant CT in breast cancer. E-cadherin-160 genotype represents a valid risk factor for HSIL and CIS. Larger aggregates were observed when increasing concentrations of chrysotile were added to the solution. Ictal EEG showed high correlation with the apneic episodes, confirming the diagnosis of apneic seizures. Accurate assessment is essential for differentiating between normal and abnormal growth.

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