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Bexomer (Eszopiclone)
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Bexomer

This medication is used to treat a certain sleep problem (insomnia). It may help you fall asleep faster, stay asleep longer, and lessen how often you wake up during the night, so you can get a better night's rest. Bexomer belongs to a class of drugs called sedative-hypnotics. It acts on your brain to produce a calming effect. Use of this medication is usually limited to short treatment periods of 1 to 2 weeks or less. If your insomnia continues for a longer time, talk to your doctor to see if you need other treatment.

Other names for this medication:
Bexomer, Eszopiclone, Fulnite, Zolnite, Zopimin, Zopipure

Similar Products:
Xeloda, Detrol, Pepcid, Avana, Temovate, Cialis, Sovaldi, Maxolon

Also known as: Eszopiclone

Description

Bexomer along with other Z-drugs are the most commonly prescribed sedative hypnotics in the United States. Eszopiclone is not marketed in the European Union following a 2009 decision by the EMA denying it new active substance status, in which it ruled that eszopiclone was too similar to zopiclone to be considered a new patentable product. Eszopiclone is now available in a generic form in the United States as of May 2014. On May 15, 2014, the USFDA asked that the starting dose of Bexomer be lowered from 2 milligrams to 1 milligram after it was observed in a study that even 8 hours after taking the drug at night, some patients were not able to cope with their next-day activities like driving and other activities that require full alertness. It works by interacting with the GABA receptors.

Bexomer is slightly effective in the treatment of insomnia where difficulty in falling asleep is the primary complaint. Kirsch et al. found the benefit over placebo to be of questionable clinical significance. Although the drug effect and the placebo response were rather small and of questionable clinical importance, the two together produce a reasonably large clinical response. It is not recommended for chronic use in the elderly.

Dosage

Usual Adult Dose for Insomnia:

Initial dose: 1 mg orally once a day immediately before bedtime Maintenance dose: 1 to 3 mg orally once a day immediately before bedtime Maximum dose: 3 mg/day Comments: -The lowest effective dose should be used. -Patients should be monitored for cognitive and/or motor impairments, especially if this drug is used repeatedly. -Patients should be reevaluated if insomnia persists after 7 to 10 days of treatment.

Usual Geriatric Dose for Insomnia:

Initial dose: 1 mg orally once a day immediately before bedtime Maintenance dose: 1 to 2 mg orally once a day immediately before bedtime Maximum dose: 2 mg/day Comments: -The lowest effective dose should be used. -Patients should be monitored for cognitive and/or motor impairments, especially if this drug is used repeatedly. -Patients should be reevaluated if insomnia persists after 7 to 10 days of treatment.

Detailed Bexomer dosage information

Overdose

According to the U.S. Prescribing Information, overdoses of Bexomer up to 90 times the recommended dose have been reported in which the patient fully recovered. According to the May 2014 edition of the official U.S. Prescribing Information, fatalities have been reported only in cases in which eszopliclone was combined with other drugs or alcohol.

Texas poison control centers reported that during 2005–2006 there were 525 total Bexomer overdoses recorded in the state of Texas, the majority of which were intentional suicide attempts.

If consumed within the last hour, Bexomer overdose can be treated with the administration of activated charcoal or via gastric lavage.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Do not share this medication with others. It is against the law.

Side effects

The most common side effects associated with Bexomer are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid taking Bexomer during travel, such as to sleep on an airplane. You may be awakened before the effects of the medication have worn off. Amnesia (forgetfulness) is more common if you do not get at least 8 hours of sleep after taking Bexomer.

Avoid drinking alcohol. Dangerous side effects or death could occur.

Avoid taking eszopiclone within 1 hour after eating a high-fat or heavy meal. This will make it harder for your body to absorb the medication.

Eszopiclone can cause side effects that may impair your thinking or reactions. You may still feel sleepy the morning after taking this medicine. Until you know how this medicine will affect you during waking hours, be careful if you drive, operate machinery, pilot an airplane, or do anything that requires you to be awake and alert.

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