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Biolar (Lorazepam)

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Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication. It is used to treat anxiety disorders, trouble sleeping, active seizures including status epilepticus, alcohol withdrawal, and chemotherapy induced nausea and vomiting, as well as for surgery to interfere with memory formation and to sedate those who are being mechanically ventilated. While it can be used for severe agitation, midazolam is usually preferred. It is also used, along with other treatments, for acute coronary syndrome due to cocaine use. It can be given by mouth or as an injection into a muscle or vein. When given by injection onset of effects is between one and thirty minutes and effects last for up to a day.

Other names for this medication:
Almazine, Anxilor, Anxionil, Anxipose, Atipam, Biokalm, Biolar, Calmese, Dulozep, Larosh, Larpose, Lopam, Lopez, Loracalm, Lorakar, Loralite, Lorazam, Lorazepam, Lorazine, Loricon, Loripam, Lorivan, Lorpam, Lorvin, Lotweet, Nexlor, Norpose, Olraz, Trapex, Urpam, Zelor, Zepatrac, Zepnap

Similar Products:
Benicar, Temovate, Provera, Clozaril, Loxitane, Adipex, Ambien, Antivert, Eriacta, Ilosone

Also known as: Lorazepam


Lorazepam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen) that is used to treat a seizure emergency called status epilepticus. Lorazepam injection is also used as a sedative to help you relax before having surgery.


Lorazepam is injected into a muscle or vein by a healthcare provider.

You may need to receive only one dose of lorazepam if your condition improves after the injection.

After the injection, you will be watched to make sure the medicine is working and does not cause harmful side effects.

Lorazepam injection is for single or occasional use. Ongoing use may be habit-forming or cause long-lasting withdrawal symptoms when you stop using the medicine.

Detailed Biolar dosage information


In a medical setting an overdose would be treated quickly.


Store Ativan at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Biolar is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Biolar are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Biolar should be avoided in people with:

Sleep apnea – Sleep apnea may be worsened by Biolar's central nervous system depressant effects. It may further reduce the patient's ability to protect his or her airway during sleep.

Myasthenia gravis – This condition is characterized by muscle weakness, so a muscle relaxant such as Biolar may exacerbate symptoms.

Pregnancy and breast feeding – Biolar belongs to the Food and Drug Administration (FDA) pregnancy category D, which means it is likely to cause harm to the developing baby, if taken during the first trimester of pregnancy. Evidence is inconclusive whether Biolar, if taken early in pregnancy, results in reduced intelligence, neurodevelopmental problems, physical malformations in cardiac or facial structure, or other malformations in some newborns. Biolar given to pregnant women antenatally may cause floppy infant syndrome in the neonate, or respiratory depression necessitating ventilation. Regular Biolar use during late pregnancy (the third trimester), carries a definite risk of benzodiazepine withdrawal syndrome in the neonate. Neonatal benzodiazepine withdrawal may include hypotonia, reluctance to suck, apneic spells, cyanosis, and impaired metabolic responses to cold stress. Symptoms of floppy infant syndrome and the neonatal benzodiazepine withdrawal syndrome have been reported to persist from hours to months after birth. Biolar may also inhibit fetal liver bilirubin glucuronidation, leading to neonatal jaundice. Biolar is present in breast milk, so caution must be exercised about breast feeding.

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These polyesters are in great demand especially in the packaging industries, the medical line as well as the paint industries. Month and day of each event were categorized both into four 3-month periods (by seasons) and 12 monthly intervals. (5) Three objections to these criticisms of HG and HD are easily answered. Each major coronary artery was imaged individually in a single 3D slab in one breathhold. A study of the protective effect of glycerol, dimethyl sulfoxide, and both combined while freezing canine intestine employing an in vivo technique. In the current study, we compared the immunoglobulin G (IgG) VlsE (sixth invariant region) peptide enzyme-linked immunosorbent assay (ELISA) with the current two-tier approach of sonicate ELISA and Western blot in the serodiagnosis of Lyme facial paralysis. It also allows the detection of Stxs in blood, a key step to monitor the pathogenesis of HUS. Here the associations between change characteristics in multiple repeated measures are studied.

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Prospective trials should clarify whether T50-guided therapies improve outcomes. These cells, however, do not have insulin secretion dynamics appropriate for restoration of euglycemia in higher animals and, eventually, humans. Our study was done to estimate frequency and patterns of lower leg and foot eczemas. The anti-ischemic efficacy of tedisamil, as measured by ST segment depression and angina threshold, is comparable to that of atenolol (50 mg b.i.d.). We conclude that GCT has a self-stimulatory system for the production of MMP-9, and the ability of stromal cells to produce MMP-9 with appropriate stimuli, such as IL-1beta, and possibly in concert with other cytokines may contribute to the aggressive and potentially malignant behavior of GCT.

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A family history of cancer, physician examination, and change in diet to reduce cancer risk increased the likelihood of skin self-examination in males but not females. Pachycladin A (1) potently inhibited the proliferation of multiple cancer cell lines, without being cytotoxic to non-cancerous cells. However, surprisingly little progress was made in defining the role of RB protein in the retina. Modifications of the epithelium of the accessory sex glands in male rabbits in aseptic inflammation caused by coal tar. Some of these patients will request radical prostatectomy (RP), although outcome data in this population group are lacking. Increased lumen diameter may also trigger atherosclerotic changes that characterize the later stages of NIDDM.

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The effectiveness of a psycho-educational group after early-stage breast cancer treatment: results of a randomized French study. They can be used to assess the effect and feasibility of different scenarios and provide insight into the emergence, spread, and control of disease. Its use in products that are applied on human skin for a prolonged period of time, such as spectacle frames or hearing aids, would best be avoided. Diagnosis of lupus erythematosus disseminatus by examination of peripheral blood. Acute chylous peritonitis is defined as the onset of acute abdomen findings due to abrupt chylous fluid accumulation in the peritoneal space. A misclassification model for the non-disjunction fraction in meiosis I. Left recurrent laryngeal nerve palsy usually results from invasion or compression of the nerve caused by diseases localized within the aortopulmonary window.

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This is a consecutive single-center series of AIS patients with thoracic curves (Lenke 1 and 2) with 2-year follow-up who underwent PSF and instrumentation with the use of the following correction strategies: segmental uniplanar screws, ultra high-strength 5.5 mm steel rods, aggressive differential rod contouring, periapical Ponte osteotomies, and segmental direct vertebral derotation. Lastly, we generated hypothetical cohort data to examine whether multivariable modelling approaches can be used to control for non-independence. She received adjuvant DAV-Feron immunochemotherapy using dacarbazine, nimustine, vincristine and interferon-beta. Introduction of v-Ha-ras oncogene induces differentiation of cultured human medullary thyroid carcinoma cells. Optimising crime scene temperature collection for forensic entomology casework. Synthesis and biological activity of polyethylene glycol-mouse nerve growth factor conjugate.

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The femoral route is less risky, and the incidence of life-threatening complications is lower for femoral cannulation than for internal jugular and subclavian cannulations. Patients in support groups were compared to men enrolled in a national prostate cancer registry (Cancer of the Prostate Strategic Urological Research Endeavor). Various chronic and acute complications have been documented in almost 100,000 Iranian victims to date. More recently, oligomeric, but not dimeric, forms of Mts1 have been shown to have a neuritogenic effect when added extracellularly to hippocampal neurons. Cell-type-specific binding of the transcription factor CREB to the cAMP-response element. This is the first time that virus proteins have been used to specifically target NPs to receptor-bearing cells as well as penetration into the cell cytosol. Perspectives of probabilistic inferences: Reinforcement learning and an adaptive network compared. Transthoracic echocardiography showed an immobile mechanical valve. Attempts to prepare a soluble active NeuS enzyme have been unsuccessful. Red meat and poultry intake, polymorphisms in the nucleotide excision repair and mismatch repair pathways and colorectal cancer risk.

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The purpose of this study was to evaluate the relationship of nonalcoholic fatty liver and cardiovascular risk factors. Furthermore, IgE immunoblot analysis showed one IgE binding component (55 kDa) within PPE, six components (55 kDa, 43 kDa, 41 kDa, 32 kDa, 31 kDa, 29 kDa) within alpha-amylase and two components (31 kDa, 29 kDa) within lipase extracts. Immunoreaction products were found in the sperm in the epididymal ducts and ductus deferens. Method of carotid angiography used at the Papeete Hospital (Tahiti). Attachment of C-terminus of SDF-1 enhances the biological activity of its N-terminal peptide. Subjects prescribed beta-blockers at hospital discharge had fewer comorbid medical conditions, less pre-existing cardiovascular disease and less severe infarcts.

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Since methysergide is converted peripherally into metabolite(s) with dopamine agonistic activity, its effect on suckling-induced PRL release may be due to this action, rather than to its action on serotonin receptors. We analyzed data from the Taiwan Renal Registry Data System (TWRDS) between 2005 and 2012. Individual or combined disruption of AP-1 subunit genes in cells expressing a temperature-sensitive clathrin heavy chain results in accentuated growth and alpha-factor pheromone maturation defects, providing further evidence that AP-1 is a clathrin adaptor complex. PDL cells obtained from healthy subjects were used for in vitro experiments. However, most patients afflicted with this disorder demonstrate both qualitative and quantitative changes in CSF proteins. Inhibitory effects of tributyltin on dopamine biosynthesis in rat PC12 cells. These mapping data may be used for completing the framework of the human physical map, and also for providing a good starting point for searching disease-related genes. Serum proteins, lipoproteins, glycoproteins and cryoagglutinins in silicosis. The mechanical complexity of the hand is indisputable, but there is increasing evidence that its control is simplified in many tasks around synergic groups of muscles that effectively decrease the number of controlled degrees of freedom. Our results illustrate that elevated KIF20A expression correlates with HPV infection, clinical stage, tumor recurrence, lymphovascular space involvement, pelvic lymph node metastasis, and poor outcome in early-stage cervical squamous cell carcinoma patients.

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Secretory function of the stomach following interference of digestive with defense reflexes. Stable core virome despite variable microbiome after fecal transfer. Hypotension has been considered to be associated with renal dysfunction. The primary outcome in these patients was the accuracy of EUS in the detection of choledocholithiasis. The AHAs Environmental Assessment identifies emerging trends facing health care providers, consumers and stakeholders. A database with reference distances was introduced to guide the surgeon to obtain the best possible results. It is therefore of interest to investigate ceramic-like coatings on metallic heads.

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An evaluation of the action of different root canal irrigants on facultative aerobic-anaerobic, obligate anaerobic, and microaerophilic bacteria. Biomonitoring of occupational exposure to styrene in a plastics lamination plant. Using the hyperspectral data, which were acquired in 2015 and the proposed method, the representation wavebands sensitive to the LNC of winter wheat are found. Multiwalled carbon nanotubes (MWCNTs) are considered to be ideal multifunctional materials for biorelated applications, but there is still some controversy regarding their toxicity. We examine the clinical utility of adolescent attachment research within the context of multidimensional family therapy, an empirically supported treatment model that has incorporated developmental research, including basic research on attachment, in its assessment and intervention framework. Little is known concerning the changes of amino acid composition in different regions of the spinal cord in patients with amyotrophic lateral sclerosis (ALS). Researchers have shown that maternal confidence is an important factor in the continuation of breastfeeding. Fusarium culmorum produces two major trichothecenes, 3-acetyldeoxynivalenol and sambucinol, and some minor apotrichothecenes. Two forms of activity-dependent long-term depression (LTD) in the CNS, as defined by their sensitivity to the blockade of NMDA receptors, are thought to be important in learning, memory, and development.

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Effects of phenotype and genotype on methods for detection of extended-spectrum-beta-lactamase-producing clinical isolates of Escherichia coli and Klebsiella pneumoniae in Norway. ELUCIDATING NEW PATHWAYS TO DIMENSIONS OF ADHD SYMPTOMS IN PRESCHOOL BY JOINTLY MODELING EXECUTIVE CONTROL AND FOUNDATIONAL COGNITIVE ABILITIES. In budding yeast microtubule organizing functions are provided by the spindle pole body (SPB), a multi-layered structure that is embedded in the nuclear envelope throughout the cell cycle. Coexisting geriatric anxiety and depressive disorders may increase the risk of ischemic heart disease mortality-a nationwide longitudinal cohort study. The present results indicate that expression of genes for the GH/PRL/SL family and Pit-1/GHF-1 is coincidentally enhanced in homing chum salmon.

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Prospective descriptive study in 3 consecutive months of HIH admissions. The problem of heat activation of bacterial spores after disinfection with regard to an aerosol method of decontaminating equipment and rooms. Future research needs to evaluate whether the GDRS is useful to improve diabetes risk awareness and prevention among the general population. These results suggest that DDB1, STAT1, STAT2, and V may form part of a large multiprotein complex which leads to the targeted degradation of STAT1 by the proteasome. Women recorded their number of hot flashes daily, along with their degree of severity, using a diary for 1 week and completed the Menopause-Specific Quality of Life Questionnaire. Our experience with forty-eight segmental tibial fractures suggests that these fractures, if closed and with shortening of an acceptable initial degree and a corrected deformity, may be successfully treated with functional braces. In addition, eight screening tools in use to screen for the FMR1 gene mutation are compared with the author-developed screening tool, the Biopsychiosocial Screening Inventory for Fragile X Syndrome (BIPSSI-FX). The TA sequences and annotation are available via web interfaces and FTP downloads. Hemoperfusion with an immobilized polymyxin B fiber column improves tissue oxygen metabolism.

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We sought to investigate the fetal hemodynamic response to the acute stress of invasive procedures. In the hypothalamus, 30 and 60 min of stress resulted in a significant fall in the level of alpha(1) adrenoceptor mRNA relative to the control. These results suggest that the conditioned place preference procedure using the newly developed airtight inhalation shuttlebox constitutes an important tool for studying the rewarding effect of abused solvents. For sodium caprate (C10), the increase in the intracellular calcium level was considered to induce the contraction of calmodulin-dependent actin filaments, followed by dilation of the paracellular pathway. The rhuEPO treatment is a safe method for the cure of cancer anemia as antibodies against rhuEPO have not been shown together with PRCA among cancer patients. It is important to emphasize that lead is a fairly toxic agent and developing a non-toxic agent is one of our future goals.

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To evaluate the influence of sex steroids on leptin levels in patients with conditions in which the steroid levels are increased. A 57-year-old white male with idiopathic cardiomyopathy was taken to the operating room for explantation of his left-ventricular assist device and orthotopic heart transplantation. Penetrating trauma to the scrotum and the corpora cavernosa caused by gunshot. The method also reduces the risk of systemic thromboembolism, residual VSD, and repair disruption. Several differences between the three types of interpersonal violence are highlighted. By electron microscopy, a gold label was found exclusively in lysosomes, which showed various sizes and labeling intensity. This approach may be a promising treatment option for patients with DR. Calcium fluorometry experiments in vitro show that stimulation of sigma receptors suppressed both transient and sustained intracellular calcium elevations associated with the microglial response to these activators. The neutral hydrogen flame photometer provides similar results to the forward light-scattering laser photometer technique.

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This paper gives a brief overview of drug delivery research in Australia and New Zealand, known collectively as Australasia, in order to indicate future directions in this area of pharmaceutical research. Impact of oral submucous fibrosis on chemotherapy-induced mucositis for head and neck cancer in a geographic area in which betel quid chewing is prevalent. Therefore novel biologically-based therapeutic approaches are required. Protecting children from secondhand smoke: a mixed-methods feasibility study of a novel smoke-free home intervention. Each sinusoidal fringe is marked by a unique codeword so that an absolute fringe order can be determined by decoding the codeword. Accounting for Protein Subcellular Localization: A Compartmental Map of the Rat Liver Proteome. Five-year follow-up of posterior capsule opacification with two different silicone intraocular lenses. PCT and sTREM-1: the markers of infection in critically ill patients?.

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We now report the isolation of antibody to enamelins which stains the enamel matrix but does not cross-react with amelogenins. Comparative study of hand cleansers used in hospitals: in vitro antimicrobial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans. All patients showed focal-enhancing masses expanding the ipsilateral ultram 25 mg picture cavernous sinus. Association of variant alleles of mannose binding lectin with severity of pulmonary disease in cystic fibrosis: cohort study. To evaluate the effectiveness of a brief intervention using a pedometer and step-recording diary on promoting physical activity in people with type 2 diabetes or impaired glucose tolerance (IGT). Experimental study of the pathogenesis of tabagic pulmonary sclerosis. Epidemiologic studies have suggested that consumption of phytoestrogen-rich foods may protect against breast cancer, and phytoestrogens such as genistein have been reported to both inhibit and stimulate the growth of some human breast cancer cells.

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Additionally, MetS patients exhibited strikingly higher levels of endothelial activation molecules and increased cIMT than controls. Anti-CD40 therapy extends renal allograft survival in rhesus macaques. Interlaboratory variation in 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 is significantly improved if common calibration material is used. QSAR with electrotopological state atom index: human factor Xa inhibitor N2-aroylanthranilamides. We here propose that elevated temperature, as found in sunburn areas, may contribute to skin carcinogenesis as well. Nondiabetic mice of the same strain were dosed for 3 and 7 days. hominis with quinolones was associated with a good clinical response. These trade-offs include the effects of competitors and group mates, as well as the problem of predator avoidance. Previously ceftin interaction with other drugs we demonstrated that in cultured mouse lung epithelial cells exposed to bolus administration of H(2)O(2), TNF-alpha-induced NF-kappaB activity was inhibited, whereas c-Jun-N-terminal kinase (JNK) activation was enhanced via a mechanism involving TNF receptor-1 (TNF-RI).

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Dysregulation of one or more of these fusion factors entails aberrant fusion of the cytotrophoblast with the syncytiotrophoblast, which adversely affects the maintenance and integrity of the placental barrier. All measures of iodine intake, except iodine excretion measured as a urinary concentration, predicted thyroid volume. A protective effect of a carbon-free fraction of India ink against snake venom. Human breast cancer cell line Hs578T was stably transfected with cDNA for cyclooxygenase-1 or -2. Early vascular grafting to prevent upper extremity necrosis after electrical burns: indications for surgery. This study assessed both procedural volume and academic status at the 82 US centers that participated in the IMPACT-II trial. We included 13 patients with MS with NAbs and a low IFN-beta bioavailability detected by the MxA-mRNA can i drink alcohol with phenergan response in a descriptive, non-randomized trial. These data suggest that the antiangiogenic activity of IFN-alpha is dependent on frequent administration of optimal biological dose and not maximal tolerated dose. Genetic mapping by means of protoplast fusion in Bacillus subtilis.

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Surprisingly, a majority of proteins contain multiple phosphorylation sites showing different kinetics, suggesting that they serve as platforms for integrating signals. Because PGE2 preserves kidney function in glomerulonephritis, and because 12-HETE inhibits 5-lipoxygenase, the enhanced PGE2 and 12-HETE production within nephritic glomeruli after TxA2 synthase inhibition may be a superior anti-inflammatory strategy when compared with TxA2 receptor antagonism. Physical, psychosocial and economic impact of rheumatoid arthritis: a pilot study of patients seen at a tertiary care referral centre. However, the efficient stabilization of NPs without deteriorating their catalytic activity is challenging. Intraventricular administration of 10.0 microM lactate/h, but not the lower dose, significantly decreased mean numbers of colabeled AVP neurons in each structure in glucoprivic animals. Multimers formed by the rotavirus nonstructural protein NSP2 bind to RNA and have nucleoside triphosphatase activity. Recently strypsin has also been found within uterine fluid, suggesting a second potential role in hatching.

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TGFbeta-DC are resistant to maturation stimulus (LPS) and might have some correlation with the down-modulation of TLR4 expression. The presence of L-serine in the reaction medium caused a modification in the lag period and the steady-state rate expressed during the cresolase activity of tyrosinase, but no modification was observed during the expression of catecholase activity. Moreover, little evidence exists for the alternative hypothesis. Fresh guinea pig cost of albenza pulmonary artery rings, with and without an intact endothelium, were mounted in organ baths containing Krebs solution and precontracted with the prostaglandin F2alpha analogue U44069. The disease has a substantial impact on survival and requires focused pharmacological therapy. t-PA, PAI-1 and fibrin fragment D-dimer antigen levels were quantified using standards commercial ELISA methods. PDHFOMA block domains changed to well ordered cylindrical domains, inversed continuous phase, and large composite spherical domains for 5 k, 10 k, and 20 k block copolymer, respectively. Results of a survey of search of amino-acidopathies in the north of France. Advanced practice and staff nurses should know how fathers of critically ill children feel and what stresses them so they can provide interventions specific for fathers during this stressful time. Previous attempts to degrade chlorinated ethenes aerobically have produced conflicting results.

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