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Bioprim (Trimethoprim)

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This medication is a combination of two antibiotics: sulfamethoxazole and trimethoprim. It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections). It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type). This medication treats only certain types of infections. It will not work for viral infections (such as flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.

Other names for this medication:
Bacin, Balkatrin, Broncoflam, Comox, Cotrimox, Cotrimstada, Drylin, Ectaprim, Ifitrim, Infectrim, Kepinol, Kombitrim, Metrim, Neotrim, Novotrim, Plocanmad, Primotren, Regtin, Sanprima, Sigaprim, Sinersul, Spectrem, Suftrex, Sulbron, Sulfametoxazol, Terbosulfa, Trifen, Triforam, Trimesulfin, Trimexazol, Trimosazol, Trimosul, Tripur, Tritenk, Trizole, Urisept, Wiatrim, Zoltrim

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Also known as: Trimethoprim


This medication is a combination of two antibiotics: sulfamethoxazole and trimethoprim. It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections). It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type). This medication should not be used in children less than 2 months of age due to the risk of serious side effects. This medication treats only certain types of infections. It will not work for viral infections (such as flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.


Prescribing Bioprim (sulfamethoxazole and trimethoprim) tablets in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.

Bioprim should be given with caution to patients with impaired renal or hepatic function, to those with possible folate deficiency (e.g., the elderly, chronic alcoholics, patients receiving anticonvulsant therapy, patients with malabsorption syndrome, and patients in malnutrition states) and to those with severe allergies or bronchial asthma.

Hematological changes indicative of folic acid deficiency may occur in elderly patients or in patients with preexisting folic acid deficiency or kidney failure. These effects are reversible by folinic acid therapy.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include loss of appetite, vomiting, fever, blood in your urine, yellowing of your skin or eyes, confusion, or loss of consciousness.


Store at room temperature between 20 to 25 degrees C (68 to 77 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bioprim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Bioprim if you are allergic to sulfamethoxazole or trimethoprim, or if you have:

severe liver disease; kidney disease that is not being treated or monitored; anemia (low red blood cells) caused by folic acid deficiency; a history of low blood platelets after taking trimethoprim or any sulfa drug; or if you take dofetilide (Tikosyn).

Do not use Bioprim if you are pregnant. This medicine could harm the unborn baby or cause birth defects. Use effective birth control, and tell your doctor if you are pregnant or become pregnant.

Do not breastfeed while using this medicine.

This medicine should not be given to a child younger than 2 months old.

To make sure Bioprim is safe for you, tell your doctor if you have:

kidney or liver disease; a folate (folic acid) deficiency; asthma or severe allergies; a thyroid disorder; malnourishment; alcoholism; high levels of potassium in your blood; porphyria, or glucose-6-phosphate dehydrogenase (G6PD) deficiency; or if you use a blood thinner (such as warfarin) and you have routine "INR" or prothrombin time tests.

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Ethanol-induced c-Fos expression in the EW has been shown to occur in urocortin I-positive neurons. Effect of external stresses on calcium phosphate glass investigated by IR spectroscopy. Transgene expression was also observed in glomerular epithelial cells, podocytes, mesangial cells, and urothelium in the kidney. Detection of an antioxidant profile in the human brain in vivo via double editing with MEGA-PRESS. However, four exons are subject to exon skipping in some transcripts, giving rise to five splice variants. Understanding change of direction ability in sport: a review of resistance training studies. Within 6 weeks of a penetrating scleral injury that included vitreous prolapse, a 6-year-old boy developed lenticular astigmatism with a regular component of 5.5 diopters (D). Access to care has long been studied by researchers, but emphasis has shifted recently from measuring whether access is worse for the poor and uninsured to monitoring how access is changing over time. New cases of first stroke and stroke subtypes in the Dutch population in 2000 were identified through linkage of national registers and included hospitalized patients for first stroke and out-of-hospital deaths from first stroke.

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In the 14 community health centers in Xicheng District, 1752 health workers were found in our four categories, serving a population of 1.278 million. A humanized anti-M2 scFv shows protective in vitro activity against influenza. The authors evaluate the most suitable approach to be used in elderly patients suffering from non-neoplastic abdominal pathology. These biochemical effects were also linked to secondary effects on growth, condition, liver size, blood chemistry and composition, histopathology, swimming behaviour and endurance, parasite infestation, and reproduction. The possibility that polyglycolic is associated with worse longer-term outcomes has not been previously reported but is biologically plausible (catgut causes a local inflammatory reaction but is rapidly absorbed, while polyglycolic causes little inflammation but absorption takes longer). Genome maintenance and bioenergetics of the long-lived hypoxia-tolerant and cancer-resistant blind mole rat, Spalax: a cross-species analysis of brain transcriptome. Other pregnancy outcomes were not related to increased risk of mental health problems. Parents were interviewed for potential risk factors of ID and blood was taken for the analysis of haemoglobin (HB), mean corpuscular volume and serum ferritin (SF) level after obtaining a verbal consent. Herein we focus on recent studies of the limits of freezing and melting of water in the cylindrical pores of ordered mesoporous silicas with pore diameters in the range of 2-10 nm, based on vapor sorption measurements, calorimetric studies, NMR spectroscopy and cryoporometry, and neutron diffraction studies. Due to the heterogeneous nature of cancer, the success of the therapeutic agents differs among patients.

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The symptoms and recognition of post-traumatic stress reactions. Taken together, the results support the conclusion that the CBF1, 2 and 3 transcriptional activators have redundant functional activities. Ink4c and Ink4d mRNAs are maximally and periodically expressed during the G(2)/M phase of the cell division cycle, but the abundance of their encoded proteins is regulated through distinct mechanisms. Endothelin-1 (ET-1) concentrations are increased in patients with diabetes mellitus, particularly those with diabetic retinopathy, or essential hypertension. As a Caries Activity Test (CAT), detection of Lactobacilli may reveal the status of dental caries and provide valuable information for the prevention and treatment of dental caries. Yeast cultures grown to stationary phase display a significant aryl alcohol dehydrogenase activity by degrading aromatic aldehydes to the corresponding alcohols.

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The objectives were to determine the incidence of drug-related deaths in a university hospital and to find out which drugs are most commonly involved in these cases. Ureaplasma urealyticum has been linked to several diseases including pneumonia and chronic lung disease (CLD) in premature infants. Surface-exchange of NOx and NH3 above a winter wheat field in the Yangtze Delta, China. Microgeographic variation of HLA-A, -B, and -DR haplotype frequencies in Tuscany, Italy: implications for recruitment of bone marrow donors. The case presented demonstrates a sequential occurrence of anisocoria, bilateral cataract formation, iritis, and macular cyst formation, with resolution following medical and surgical treatment. A recombinant form of this protein expressed in bacterial cells was able to cleave a synthetic trypsin-sensitive substrate, D-Ile-Phe-Lys pNA. Using principal component analysis, the factor structure of the BIS-11 was also evaluated. Differential hormonal regulation of carbonyl reductase activities in liver and kidney microsomes of rat. The preparation of the polyhydroquinolines by a three-component reaction was achieved by using ionic liquid-phase bound beta-oxo esters.

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Transformation of bone marrow B-cell progenitors by E2a-Hlf requires coexpression of Bcl-2. The animals were subjected to standardized liver trauma 1 week later. Douching has been linked to bacterial vaginosis as well as to chlamydial cervicitis in some, but not all, studies. Studies that advance understanding of how and why patients prioritize their various conditions are essential to providing care that is patient-centered, reflecting what matters most to the individual while improving their health. Our previous findings suggest that myopia can be slowed by wearing progressive lenses, and one possible mechanism for this is through the oculomotor system. For large phantoms, equivalent to a human head, the temporal subtraction is more suitable for detecting elements such as iodine, keeping a reasonable x-ray dose delivered to the phantom. The action of androgens in the lower urinary tract and pelvic floor is complex and may depend on their anabolic effects, hormonal modulation, receptor expression, interaction with nitric oxide synthase, or a combination of these effects. Imaging for staging, such as magnetic resonance imaging or computed tomography, still has a low accuracy compared with pathological specimens. Excitability of muscle and brain and their sorption of dyes during hyperpolarization.

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This is the first demonstration of significant changes in the complex of aerobic and facultatively anaerobic nitrogen fixers mediated by an extension of microbial group composition and a shift in dominant taxa in termites that cannot reutilize their feces. Morphological observation on the effect of acupuncture on mast cells at the zusanli point. The pituitary homeobox1 gene (Ptx1) was initially identified as encoding a pituitary-restricted transcription factor for the proopiomelanocortin (POMC) gene. Evidence for substrate-specific requirement of the splicing factor U2AF(35) and for its function after polypyrimidine tract recognition by U2AF(65). Furthermore, we demonstrated that the gp130-mediated increase in survival of infected myocytes occurred through a signal transducers and activators of transcription-3-dependent mechanism that did not affect viral replication. We present a sophisticated, non-linear model of leaching abatement costs, and a simple model of nitrogen stocks. A Cobb angle was drawn and analyzed on each radiograph, so pre and post comparisons could be made. A three-stage operative approach was undertaken comprising buspar usual dose resection of the atretic loop and colostomy, posterior sagittal anorectoplasty a few months later, and finally closure of the colostomy. The present case represents a new association of IM with an autoimmune disease and gives support to the hypothesis of a possible immune basis of some IM cases. Decisions about target and tissue selection and delineation affect the balance of reward and the risk of highly conformal RT.

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Plasma samples were obtained from 101 consecutive, critically ill patients admitted to the intensive care unit with different severities of microbial infection, as defined by standardized criteria. Cognitive behavior therapy vs exposure in vivo in the treatment of panic disorder with agoraphobia (corrected from agrophobia). Each masticatory cycle included a jaw closing (Cl) phase consisting of a fast-closing (FC) and a slow-closing (SC) phase, and a jaw opening (Op) phase. Bronchoplastic resections achieve local control and long-term survival comparable to standard resections in patients with stage I or II disease, and may be considered as a valuable alternative to pneumonectomy. Identification and expression of human cytomegalovirus UL148 mRNA of low-passage clinical isolates in Guangzhou.

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Temporary transvenous electric stimulation and intracardial pressure measurement with a microcatheter. The functional anatomy of MR defined by TEE is strongly and independently predictive of valve repairability and postoperative outcome. Pro-opiomelanocortin mRNA expression in the arcuate nucleus increased in late compared to early pregnancy: the number of positive neurones significantly increased losartan potassium cozaar 50 mg tab in the caudal region. The effect of increasing exposures of the 10-B(n,alpha)7-Li reaction on the skin of man. The objective of this study was to quantify active stability provided by eight shoulder muscles in mid-range and end-range positions through muscle force vector analysis. In the present study, we demonstrate the potential of the human NIS gene (hNIS) as a reporter gene. Mixed cryoglobulinemia is a highly heterogeneous clinical syndrome in terms of clinical presentation, extent and severity of organ involvement, immunological abnormalities and clinical course. Health service utilization data were obtained from Medicaid and from state and local departments of mental health. Basic properties of apatite cement containing spherical tetracalcium phosphate made with plasma melting method.

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The study used a qualitative approach of semi-structured interviews, focus groups, site visits to the hospitals and review of relevant literature to ascertain what participants saw as the necessary ingredients to create regional NIS. Absolute, unambiguous ultramicroanalysis of metabolites present in complex biological extracts. Using innovative simulation modalities for civilian-based, chemical, biological, radiological, nuclear, and explosive training in the acute management of terrorist victims: A pilot study. Not all domains are present in each cell-envelope proteinase, suggesting that these multi-domain proteins are the result of gene shuffling and imuran cost usa domain swapping during evolution. Furthermore, a subset of downregulated genes related to endocytosis and protein secretion was able to discriminate MDS from MDS-AML. There were 15 heart, 12 lung (4 bilateral), and 12 heart-lung transplants.

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In summary, we could not show beneficial effects of L-carnitine administration in hemodialysis patients for the dosage and duration of treatment stated, either on phagocytic function and viability or on the clinical and biochemical parameters observed. Capsaicin pretreatment resulted in a depletion of both substance P and CGRP immunoreactivity, but had no apparent effect on PGP 9.5 immunostaining. Behavior of the cardiovascular system in patients given anesthesia with solutions containing vasoconstrictor hormone. The financial costs of delivery exacerbated are thought to continue to represent a major barrier to care to accessing services. Transient Noise Reduction in Cochlear Implant Users: a Multi-Band Approach. Surface application of zoledronate and alendronate reduces root resorption of replanted teeth in animal models. The effect of complex stoichiometry in supramolecular chirality transfer to zinc bisporphyrin systems. Staff time, patient well-being, and data integrity top the list of concerns. levlen dose

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Here we show that the growth of microtubules induced in fibroblasts by removal of the microtubule destabilizer nocodazole activates Rac1 GTPase, leading to the polymerization of actin in lamellipodial protrusions. One-shot phase-shifting interferometry: five, seven, and nine interferograms. Effect of bongkrekic acid on the adenine nucleotide carrier in mitochondria: tightening of adenine nucleotide binding and differentiation between inner and outer sites. Bioadhesive controlled release systems of ornidazole for vaginal delivery. Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis. In how to take catapres 75 mg this study, 97 patients with SCA were analysed in two groups: 34 patients presenting with OVC (SCA-VC) and 63 without these complications (SCA-N). A shear-induced platelet function test (haemostatometry) was used to screen for antithrombotic potential. We sought to assess the effect of baseline ejection fraction on survival difference between patients with life-threatening ventricular arrhythmias who were treated with an antiarrhythmic drug (AAD) or implantable cardioverter-defibrillator (ICD). Interstitial nephritis caused by BK polyomavirus is a recognized complication of renal transplantation.

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Joint charts for prescription--transcription and dispensing errors. Limitations in the extent and depth of the physician-patient relationship appear to be the most frequent impediments to writing DNR orders in our institution. Amino acid changes at positions 173 and 187 in the human T-cell leukemia virus type 1 surface glycoprotein induce specific neutralizing antibodies. Augmentation of innate host defense by expression of a cathelicidin antimicrobial peptide. Dissociative experiences and posttraumatic stress disorder are often the results of this experience.

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Remarkable tolerance of an esophageal foreign body since childhood. Effect of antirheumatic nolvadex dosage steroid cycle substances on functional conditions of the liver in rheumatism. Because the outer and inner solvent passed through the membrane easily, the outside and inside of the membrane were the same at the equilibrium state. Five different pigeons were treated daily with 10 mg/kg morphine (i.m.) and trained 6 h later to discriminate among 10 mg/kg morphine, 1.0 mg/kg nalbuphine and saline. Ectopic pheochromocytomas (paragangliomas) are rare tumors that are traditionally treated with open surgery. Those from the most deprived areas and those with mental health problems are considerably more likely to be current smokers and require additional smoking cessation support. Risk of transmission of sexually transmitted diseases by cryopreserved semen. Ontogenetic development and spatial distribution of the ileal apical sodium-dependent bile acid transporter and the ileal lipid-binding protein in apoE knockout and C57BL/6 mice.

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In a different study group, TRAIL, FasL, DR5 and Fas were increased in tonsils of HIV-positive patients as compared with HIV-negative donors and HAART patients. We conclude that gemcitabine is a promising radiation sensitizer that will need to be developed cautiously if excessive normal tissue toxicity is to be avoided. Prophylactic intramuscular injection of 5 or 10 ml of ISG containing antibody to hepatitis A virus and antibody to hepatitis B surface antigen provided significant protection against development of endemic type A, type B, and non-A, non-B icteric hepatitis for six months if it was administered before exposure. For future improvement, development of a management system that can facilitate two-way trust between management and staff over the long term is recommended. The apogeotropic variant of horizontal semicircular canal benign paroxysmal positional vertigo (HC-BPPV) is attributed to canalithiasis of the anterior arm or cupulolithiasis. In this article, we aim to gain a better understanding of help-seeking behavior in depression, and how to intervene effectively decreasing treatment gap and delay by using a meta-ethnography approach-an interpretive technique to systematically synthesize qualitative data. Arthroscopic treatment of hematogenous infected total knee arthroplasty: 5 cases. The TvA functions are insufficient to separately estimate the noise and the exponent of the power function. The RecA142 protein, in which valine is substituted for isoleucine-225, is defective for genetic recombination in vivo and for DNA strand exchange activity in vitro under conventional growth and reaction conditions respectively. This study examined the effects of fat- plus sucrose-rich meals on endothelium-dependent flow-mediated vasodilation in diabetic patients.

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