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Bonestat (Calcitriol)

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Bonestat is a man-made active form of vitamin D. Most people get enough vitamin D from exposure to the sun and from fortified food products. Vitamin D helps control parathyroid hormone and the levels of certain minerals that are needed for building and keeping strong bones.

Other names for this medication:
Actical, Alfacal, Alfacalcirol, Alfacip, Alfarich, Alphadol, Arachitol, Arcium, Aristrol, Biocal, Calasto, Calcibest, Calcicare, Calcikind, Calcitriol, Caldikind, Caldix, Calfa, Calosto, Calotec, Calsonic, Calsure, Caltive, Caltop, Calvical, Coecoral, Denscal, Dmcal, Lctrol, Minroset, Ostonex, Ostriol, Refirm, Rical, Riecal, Rockbon, Roical, Rolsical, Septriol, Solbiocal, Sorvate, Statbone, Sunmic, Tobalt, Trolec, Vitalpha, Zaxial

Similar Products:
Wellbutrin, Deltasone, Propecia, Ceftin, Fasigyn, Mircette, Avelox, Azulfidine, Amaryl

Also known as: Calcitriol


Generic Bonestat is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Bonestat are intestine and bone. Generic Bonestat receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Bonestat may also act on the kidney and the parathyroid glands. Generic Bonestat is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Bonestat has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Bonestat, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Bonestat in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Bonestat produces other independent beneficial effects. Bonestat is also known as Calcitriol. Generic Bonestat treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Bonestat is Calcitriol. Brand name of Generic Bonestat is Bonestat.


Generic Bonestat is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Bonestat suddenly.


If you overdose Generic Bonestat and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Bonestat are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Overproduction of lon protease restored mitochondrial function and also diminished the insulin resistance induced by treatment xanax drug test with cholesterol and palmitate. Reconstitution of immunohemopoietic functions in lethally irradiated mice transplanted with unseparated or T-cell-depleted syngeneic bone marrow grafts. Prescription drug labeling medication errors: a big deal for pharmacists. These genes include cyclooxygenase-2 (COX-2), Bcl-2, BclX(L) and c-Myc, which influence diverse processes such as angiogenesis, proliferation and apoptosis. Study of various rhubarbs regarding the cathartic effect and endotoxin-induced disseminated intravascular coagulation. Most cases of pulmonary edema presenting with hypercalcemia are associated with malignant hypercalcemia and related with metastatic calcification. Stimulation of an N-ethylmaleimide-sensitive ATPase in the collecting duct segments of the rat nephron by metabolic acidosis. The migration of 1381 Tokelauans 15 years and over to New Zealand leaving 811 in Tokelau, provided a unique opportunity to test centuries of speculation on the impact of environment on rheumatic disease.

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Synthesis of certain heterodimers expected as HIV-1 reverse transcriptase inhibitors. Retrospective analysis of linked Scottish cancer registry and hospital discharge data for colorectal cancer. The 2000 NHIS was conducted in 38,632 households in a clustered sample representative of the 48 contiguous states in the United States. Base triggered release of insecticide from bentonite reinforced citric acid crosslinked carboxymethyl cellulose hydrogel composites. We report the case of a young woman who presented with gait disturbance and alcohol withdrawal, and who was eventually diagnosed with CPM. Sepsis is common, highly morbid, and costly, yet little is known about differences in the care or outcomes of patients with sepsis across hospitals.

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To assess the efficacy of topical capsaicin in the treatment of vulvar vestibulitis syndrome. Chemical modification of the enzyme and the kinetics of inactivation, and protection by substrate, indicated the involvement of carboxyl groups in the catalytic function of the enzyme. We found that splenocytes of Lew.1A rats, previously transfused with Lew.1W blood and grafted with Lew.1W heart, contained suppressor cells which inhibited the capacity of autologous lymphocytes to produce IL2 upon Lew.1W challenge. Interestingly, medaka hey1 is also expressed in the dorsal aorta and the heart, two tissues where hey2, but not hey1, is expressed in zebrafish. The structure of the novel 120-kDa subunit found in the embryonic fibroblasts and the 90-kDa subunit found in adult chicken gizzard and the ligand specificities of these novel combinations of alpha v are not known at present, but these integrins are RGD specific. The bioactivity tests, performed in simulated body fluid after biomimetic coating, showed that a dense film of calcium phosphate was formed after 30 days. The spectrum of symptoms of hyperprolactinemia and the clinical features of acromegaly are elaborated, and the various medical therapeutic options for management of prolactinomas and somatotroph adenomas are discussed. The involvements of matrix metalloproteinase-9 (MMP-9) and urokinase plasminogen activator (uPA) in the pathogenesis of various types of lung cancers have been established. Mouse mutants for the study of corticotropin-releasing hormone receptor function: development of novel treatment strategies for mood disorders.

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Griseofulvin-induced aneuploidy and meiotic delay in mouse oocytes: effect of dose and harvest time. In the current study we wanted to determine whether postoperative events influence the likelihood of delayed neurologic deficit, independent of preoperative risk factors. Death related to albendazole-induced pancytopenia: case report and review. The embryo probably represents a longitudinal mirror duplication of head and all 3 thoracic segments. Impairment of leukocyte trafficking in a murine pleuritis model by IL-4 and IL-10. Primary and secondary prophylaxis of chronic lung diseases in a rural locality. We highlight the dearth of large-scale, comprehensive, community-based, clinical, and translational research in this area, especially the limited skin-bleaching-related research among non-White populations in the US. In this study, we investigated genomic and expression differences between three cisplatin-sensitive and their paired cisplatin-resistant lines using combined whole-genome screen approaches. All virulence genes tested, except afa/dra and hlyD, were detected among the E.

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