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Bonine (Meclizine)

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Bonine, sold under the brand name Bonine, among others, is an antihistamine used to treat motion sickness and dizziness (vertigo). It is taken by mouth. Effects generally begin in an hour and last for up to a day. Bonine was patented in 1951 and came into medical use in 1953. It is available as a generic medication and often over the counter.

Other names for this medication:
Bonine, Comfurt, Diligan, Meclizine, Pregnigoxin, Progenidoxin, Pyrinate

Similar Products:
Nimotop, Atarax, Actos, Sustiva, Plavix, Cardizem, Starlix

Also known as: Meclizine


Meclizine is used to prevent and control nausea, vomiting, and dizziness caused by motion sickness. It is also used for vertigo (dizziness or lightheadedness) caused by ear problems.

Meclizine is an antihistamine. It works to block the signals to the brain that cause nausea, vomiting, and dizziness.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain meclizine. It may not be specific to Bonine/25. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

Chew or crush the chewable tablet completely before swallowing. Do not swallow it whole.

Swallow the non-chewable tablet whole. Do not crush, chew, or break it.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets): For nausea, vomiting, and dizziness caused by motion sickness: Adults—At first, 25 to 50 milligrams (mg) taken 1 hour before travel. You may take another dose once every 24 hours while traveling. Children 12 years of age and older—Use and dose must be determined by your doctor. Children younger than 12 years of age—Use is not recommended. For vertigo: Adults—25 to 100 milligrams (mg) per day, taken in divided doses. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Meclizine dosage information

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of Bonine® tablets and chewable tablets in children or Bonine®/25 or Bonine®/50 tablets in children younger than 12 years of age. Safety and efficacy have not been established.

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