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Budeprion (Bupropion)

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Budeprion is a norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation. Budeprion is indicated for the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation.

Other names for this medication:
Aplenzin, Budeprion, Bupdep, Bupraset, Bupron, Bupropion, Ession, Nicotex, Smoquit, Unidep, Zyban

Similar Products:
Noroxin, Ambien, Starlix, Zebeta, Benemid, Rebetol, Zyvox, Valtrex, Nexium

Also known as: Bupropion


{name} XL is an antidepressant used to treat major depressive disorder and seasonal affective disorder. The Zyban brand of bupropion is used to help people stop smoking by reducing cravings and other withdrawal effects.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Too much of this medicine can increase your risk of a seizure.

You may take Budeprion SR with or without food.

Swallow the extended-release tablet whole and do not crush, chew, or break it.

You should not change your dose or stop using Budeprion SR suddenly, unless you have a seizure while taking this medicine. Stopping suddenly can cause unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

If you take Zyban to help you stop smoking, you may continue to smoke for about 1 week after you start the medicine. Set a date to quit smoking during the first 2 weeks of treatment. Talk to your doctor if you have trouble quitting after taking Zyban for 7 to 12 weeks.

Your doctor may prescribe a nicotine replacement product (such as patches or gum) to help you stop smoking. Start using the nicotine replacement product on the same day you stop (quit) smoking or using tobacco products.

Some people taking Budeprion SR (Budeprion or Zyban) have had high blood pressure that is severe, especially when also using a nicotine replacement product (patch or gum). Your blood pressure may need to be checked before and during treatment with this medicine.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

You may have nicotine withdrawal symptoms when you stop smoking, including: increased appetite, weight gain, trouble sleeping, trouble concentrating, slower heart rate, having the urge to smoke, and feeling anxious, restless, depressed, angry, frustrated, or irritated. These symptoms may occur with or without using medication such as Zyban.

Smoking cessation may also cause new or worsening mental health problems, such as depression.

This medicine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use Budeprion SR.

Store at room temperature away from moisture, heat, and light.

Detailed Budeprion SR dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Budeprion XL can be fatal. Overdose symptoms may include muscle stiffness, hallucinations, fast or uneven heartbeat, shallow breathing, or fainting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Side effects

The most common side effects associated with Budeprion are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Budeprion SR if you are allergic to it, or if you have:

a seizure disorder; an eating disorder such as anorexia or bulimia; or if you have suddenly stopped using alcohol, seizure medication, or a sedative (such as Xanax, Valium, Fiorinal, Klonopin, and others).

Do not use an MAO inhibitor within 14 days before or 14 days after you take Budeprion SR. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Do not take Budeprion SR to treat more than one condition at a time. If you take this medicine for depression, do not also take Budeprion SR to quit smoking.

Budeprion SR may cause seizures, especially if you have certain medical conditions or use certain drugs. Tell your doctor about all of your medical conditions and the drugs you use.

Tell your doctor if you have ever had:

a head injury, seizures, or brain or spinal cord tumor; narrow-angle glaucoma; heart disease, high blood pressure, or a heart attack; diabetes; kidney or liver disease (especially cirrhosis); depression, bipolar disorder, or other mental illness; or if you drink alcohol.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Ask your doctor about taking this medicine if you are pregnant. It is not known whether Budeprion SR will harm an unborn baby. However, you may have a relapse of depression if you stop taking your antidepressant. Tell your doctor right away if you become pregnant. Do not start or stop taking this medicine without your doctor's advice.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of bupropion on the baby.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Budeprion SR is not approved for use by anyone younger than 18 years old.

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Safety of nortriptyline at equivalent therapeutic doses for smoking cessation: a systematic review and meta-analysis. This indicates that either thyroid hormones act directly and specifically on slow motoneurons or that conversion of the muscle fibers by thyroid hormones produces secondary changes in the motoneuron. FoxO1 can regulate bone mass by affecting osteoblasts, osteoclasts, and precursor cells. Retrospective, clinicopathologic analysis of our experience and a review of recent literature. Phospholipase C-gamma1 (PLC-gamma1), which interacts with a variety of signaling molecules through its two Src homology (SH) 2 domains and a single SH3 domain has been implicated in the regulation of many cellular functions. S100B protein is a calcium-binding molecule, mainly secreted by glial cells, which, depending on its concentration, has a trophic or toxic effect on neuronal cells. The results of RAPD-PCR revealed the most genetic diversity among poultry isolates, while human isolates showed the least genetic diversity.

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This is the first study to demonstrate an important biochemical change in E7 function caused by a naturally occurring variation, and we suggest that the N29S variant merits further assessment to determine whether it has an increased association with the development of HPV-associated malignancies. However, further studies are needed to associate the instability with specific IBS symptoms or with specific bacterial groups and species. Palliative treatments for unresectable hepatic malignancies should minimize tumor-related symptoms and extend overall survival. To analyze these properties, excised inside-out membrane patches containing either the native channel from salamander olfactory-receptor neurons or a recombinant rat olfactory cyclic nucleotide-gated channel were exposed to short pulses of known concentrations of cAMP or cGMP to mimic a rapid and transient production of second messenger. These recommendations emphasised the importance of a clear and consistent organisational approaches to disruptive clinician behaviour. Diabetic pulmonary fibrosis is a severe disease that increases mortality risk of diabetes. To explore whether the functions of C-I TRIM proteins are conserved in invertebrates, we analyzed Caenorhabditis elegans and Drosophila trim-9 mutants.

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P1.HTR, an immunogenic variant of the P815 mastocytoma cell line, was used to generate stably transfected cell clones with expression vectors encoding the human CD134L transmembrane protein fused with either mouse IL-22BP or IL-9. Human thermolabile phenol sulfotransferase gene (STM): molecular cloning and structural characterization. However, the strength of these priority effects can be variable, in part because of strong site and year effects. Clinical photographs and impressions were taken prior to the surgical intervention as well as after crown placement and at first and second annual checkups. Sudden cardiac death (SCD) persists as one of challenging problems in cardiology and cardiac surgery, only in Russia costing more than 350,000 deaths annually. Is treating cardiac hypertrophy salutary or detrimental: the two faces of Janus. All patients were investigated prospectively regarding indications, wound infections, other complications and mortality between 1999-10-01 and 2000-09-30. This gene was mainly expressed in the spermatocyte, judging from the result of in situ hybridization. Statistical density dependence was, in the sense of a stochastic equilibrium or return tendency, detected in all of the grasshopper mean density time-series from the three major physiographic regions of the state, Northern Glaciated Plains, Southern Unglaciated Plains, and Western Mountains.

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Stem cells in the injured spinal cord: reducing the pain and increasing the gain. An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy. Fetal bone marrow derived MSCs should be enough to sustain a steady supply of low differentiated cells for proliferation, hence an abundant and accessible cellular reservoir for stem cell bioengineering, whereas adult bone marrow derived MSCs are more useful in hematopoietic reconstitution in bone marrow transplantation. Enhanced negativity of the face-specific N170 was elicited by emotional as opposed to neutral faces, followed by the occipital negativity (240-340 ms poststimulus). In patients with clinically suspected TLE, MR imaging alone is able to localize temporal lobe foci correctly. These 2 approaches offer different risks and benefits which are discussed in this review. Pubic Osteomyelitis in a Combat Training Soldier: A Case Report. The existence of this hypothetical complex was verified by two independent biochemical techniques.

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Systemic hypertension, left ventricular hypertrophy and coronary artery disease. The lesion is associated with increasing pain until the larva exits the skin. A total of 42 consecutive patients seen over a 3-month period with ocular and orbital rubber bullet injuries were assessed clinically and radiographically within 1 day of injury, and the findings were recorded. We combine this approach with the classical incompatibility condition and illustrate its algorithmic implementation within a fully nonlinear FE approach. Our study convincingly shows that variants in AGBL5 are associated with arRP. Out of 10 signs evaluated, seven were statistically significant: wet dog shakes, body tremor, paw tremor, piloerection, mastication, genital licks and sniffing. In view of the similarity between this disease and spondylarthropathies in humans, the data suggest that endogenous IFNgamma may also play a disease-promoting role in the human condition and thus may serve as a target for therapy. The other two valves presented lipid degeneration of the spongiosa in one and diffuse fibrous degeneration in the other. When compared with a random peptide library, WAARG libraries contain more native-like binding peptides at a significantly smaller size. In an attempt to identify mechanisms that explain the difference in susceptibility of two rat strains to the induction of experimental autoimmune myasthenia gravis (EAMG), acetylcholine receptor (AChR)-reactive antibodies were tested for their ability to up-regulate levels of inducible nitric oxide synthase (iNOS) in skeletal muscles of disease-sensitive Lewis rats and disease-resistant Wistar Furth (WF) rats.

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Femtosecond transient absorption spectroscopic study of a carbonyl-containing carotenoid analogue, 2-(all-trans-retinylidene)-indan-1,3-dione. More than half of the distinct mutations have been previously reported in CADASIL patients. Normovolemic hemodilution of autologous fresh frozen plasma in surgery of the spinal cord in children. Lens epithelial cell reaction after implantation of different intraocular lens materials: two-year results of a randomized prospective trial. However, there is limited knowledge of the epidemiology and associations of such estimates in cardiac surgery patients. To evaluate the cost-effectiveness of caspofungin versus liposomal amphotericin B (L-AmB) for empirical antifungal therapy in patients with persistent fever and neutropenia in Sweden. Regardless of mode and/or frequency of the stimulation plasma and/or CSF beta-EP levels were significantly increased. Results are presented to provide guidelines for management of these injuries. The plasma contact system sits atop the intrinsic coagulation cascade and plasma kallikrein-kinin pathway, and in vivo its activation contributes, respectively, to coagulation and inflammation mainly via two downstream pathways. A 24-year-old man presented with severe low-back pain and paraspinal muscle spasm after exertion.

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Cross-sectional study including 100 community-dwelling women and men 75 years and older. The serum levels of ubiquinone depend mostly on the amount of ubiquinone-containing lipoproteins in circulation. A high level of enzyme synthesis is connected with transcription from PL, PR and tac promoters. To evaluate psychosocial factors and patterns on suicidal ideation of the undergraduates in Shanxi province. The aim of this study was to assess the impact of probiotic use in terms of number of RTI episodes and days averted, and the number of antibiotic prescriptions and missed workdays averted, in the general population of Canada.

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Studies suggest that fear of recurrence is a significant burden. Incomplete processing of the protein and enzymatic removal of the oligosaccharides chain or the terminal sialic acids from neuroligin-1 enhance its activity, whereas deglycosylation of neurexin-1beta did not alter its association capacity. A clinicopathological study of resected subcentimeter lung cancers: a favorable prognosis for ground glass opacity lesions. A systematic review on the effectiveness of nurse-led cardiac clinics for adult patients with coronary heart disease. With the relatively small numbers of events in PET, and with Poisson statistics for which variance equals the mean, the noise sensitivity of standard CT algorithms becomes limiting.

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Indocyanine green applications in plastic surgery: A review of the literature. Secondary outcome included the incidence of successful blockade, performance time, onset of sensory block, duration of is cleocin an antibiotic analgesia, and complication rates. However, recent improvements have resulted in improved stroke morbidity rate that may approach that of CEA. In this two-step process, we first constructed by targeted recombination a mutant of FIPV, designated mFIPV, in which the ectodomain of the spike glycoprotein was replaced by that of MHV. Using nomograms simplifies the selection of statistical QC procedures to limit the number of erroneous patient results reported due to an increase in analytical random error. In bovine primary cerebral endothelial cells, nontoxic levels of PBCA particles and polysorbate-80 did not increase paracellular transport of sucrose and inulin in the monolayers.

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