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Bupdep (Bupropion)

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Bupdep is an antidepressant medication used to treat major depressive disorder and seasonal affective disorder. The Zyban brand of Bupdep is used to help people stop smoking by reducing cravings and other withdrawal effects.

Other names for this medication:
Aplenzin, Budeprion, Bupdep, Bupraset, Bupron, Bupropion, Ession, Nicotex, Smoquit, Unidep, Zyban

Similar Products:
Fasigyn, Mellaril, Floxin, Cymbalta, Suprax

Also known as: Bupropion


{name} SR is an antidepressant used to treat major depressive disorder and seasonal affective disorder. The Zyban brand of bupropion is used to help people stop smoking by reducing cravings and other withdrawal effects.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Too much of this medicine can increase your risk of a seizure.

You may take Bupdep SR with or without food.

Swallow the extended-release tablet whole and do not crush, chew, or break it.

You should not change your dose or stop using Bupdep SR suddenly, unless you have a seizure while taking this medicine. Stopping suddenly can cause unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

If you take Zyban to help you stop smoking, you may continue to smoke for about 1 week after you start the medicine. Set a date to quit smoking during the first 2 weeks of treatment. Talk to your doctor if you have trouble quitting after taking Zyban for 7 to 12 weeks.

Your doctor may prescribe a nicotine replacement product (such as patches or gum) to help you stop smoking. Start using the nicotine replacement product on the same day you stop (quit) smoking or using tobacco products.

Some people taking Bupdep SR (Bupdep or Zyban) have had high blood pressure that is severe, especially when also using a nicotine replacement product (patch or gum). Your blood pressure may need to be checked before and during treatment with this medicine.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

You may have nicotine withdrawal symptoms when you stop smoking, including: increased appetite, weight gain, trouble sleeping, trouble concentrating, slower heart rate, having the urge to smoke, and feeling anxious, restless, depressed, angry, frustrated, or irritated. These symptoms may occur with or without using medication such as Zyban.

Smoking cessation may also cause new or worsening mental health problems, such as depression.

This medicine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use Bupdep SR.

Store at room temperature away from moisture, heat, and light.

Detailed Bupdep SR dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Bupdep XL can be fatal. Overdose symptoms may include muscle stiffness, hallucinations, fast or uneven heartbeat, shallow breathing, or fainting.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bupdep are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Bupdep SR if you are allergic to it, or if you have:

a seizure disorder; an eating disorder such as anorexia or bulimia; or if you have suddenly stopped using alcohol, seizure medication, or a sedative (such as Xanax, Valium, Fiorinal, Klonopin, and others).

Do not use an MAO inhibitor within 14 days before or 14 days after you take Bupdep SR. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Do not take Bupdep SR to treat more than one condition at a time. If you take this medicine for depression, do not also take Bupdep SR to quit smoking.

Bupdep SR may cause seizures, especially if you have certain medical conditions or use certain drugs. Tell your doctor about all of your medical conditions and the drugs you use.

Tell your doctor if you have ever had:

a head injury, seizures, or brain or spinal cord tumor; narrow-angle glaucoma; heart disease, high blood pressure, or a heart attack; diabetes; kidney or liver disease (especially cirrhosis); depression, bipolar disorder, or other mental illness; or if you drink alcohol.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Ask your doctor about taking this medicine if you are pregnant. It is not known whether Bupdep SR will harm an unborn baby. However, you may have a relapse of depression if you stop taking your antidepressant. Tell your doctor right away if you become pregnant. Do not start or stop taking this medicine without your doctor's advice.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of bupropion on the baby.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Bupdep SR is not approved for use by anyone younger than 18 years old.

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Possibility of remission induction in acute myeloid leukemia by granulocyte colony-stimulating factor. Each pancreatic section was histologically examined, and mean cumulative scores (MCSs) were assigned for 8 histologic characteristics. Therefore, physiologically relevant models of metabolic drug-drug interaction will likely play increasingly important roles in improving quantitative predictions and in the assessment of the influential factors underlying the interactions. The lifespans are divided into phases, each phase having linear rates. Transcriptome analysis of Arabidopsis mutants suggests a crosstalk between ABA, ethylene and GSH against combined cold and osmotic stress. Thus, EGF specifically induces K6 and K16, markers of activated keratinocytes, via nuclear proteins that bind to EGF-responsive elements in the promoters of these keratin genes. Furthermore, our data indicated that the increase in the relative amount of the crystalline phase may be primarily attributed to temperature fluctuations and repeated changes in pressure, which could cause the hardening of EVA and eventually diminish the protective ability of MGs.

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Expansins are cell wall-residing proteins that have an ability to plasticize the cellulose-hemicellulose network of primary walls. These rsDECT thresholds differ from values derived from dual-source DECT technology. The mannose receptor (MR) is involved in the initiation of the immune response and regulation of homeostasis during inflammation and tissue remodeling. Amplification of AML1 in acute lymphoblastic leukemia is associated with a poor outcome. The review identified nine policy options, which were being implemented in Africa, but the most common was task shifting which had success in several African countries.

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Sepiolite from Franklin is of moderate crystallinity and consists of soft, flexible mass-fiber. Mice were subjected to gamma irradiation or intravenous etoposide administration, followed by cell fractionation and immunofluorescence studies of various organs. One successfully dilated lesion occluded 8 days after the procedure and was redilated by a larger sized balloon. Repeated partial endoscopic resections as treatment for two patients with inoperable tracheal tumours. Attended stimuli elicited enhanced ERP components in the latency range 80-200 ms that were co-localized with fMRI activations in multiple extrastriate cortical regions. In addition, they support the need for continued work on linkage of the nursing care elements of the Nursing Minimum Data Set, including nursing diagnoses, nursing interventions, and nursing-sensitive outcomes. All but one of the 13 patients achieved long-term cure with this strategy. Overall, understanding the distinct coronary vascular benefits of these agents will emphasize the importance of using them, particularly ACE inhibitors, to improve outcomes in patients with coronary atherosclerotic disease. Post hoc analysis was used to identify significant differences among racial groups.

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The result in terms of elicited chromatin condensation was not as strong as that promoted in ras-transformed NIH/3T3 cells. This supports the notion that a dorsoventral body axis inversion occurred after the separation of protostome and deuterostome lineages in evolution. The current and potential role of cryoablation as a primary therapy for localized prostate cancer. In addition, immunoreactive cytoplasmic granules were found at several sites in the ventricular myocardium. Based on the ability to ferment glycerol and arabinose and to reduce nitrate, Y. Microhabitat identity of two species of sheet-web spiders: field experimental demonstration. Agonistic interactions, cuticular and hemolymphatic lipid variations during the foraging period in spider females Brachypelma albopilosa (Theraphosidae). The effects of noise level and elevated ambient temperatures upon selected reproductive traits in female Swiss-Webster mice. CPGs dedicated to anatomic areas other than the knee, ankle, and shoulder are needed.

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Physical outcome measurements via the Internet: reliability at two Internet speeds. Several types of evidence suggest that protein-tyrosine phosphorylation is important during the growth of neuronal processes, but few specific roles, or subcellular localizations suggestive of such roles, have been defined. Bacterial isolates were identified and cultured, and antibiotic culture sensitivity tests were performed. GRK5 regulation of airway responses may have implications in obstructive airway diseases such as asthma or chronic obstructive pulmonary disease. If unrecognized and/or untreated, malignant hyperthermia can be fatal. The aim of this work was to determine hospital morbidity among the elderly. Road safety and the driver with dementia: shifting the debate up a gear. Analysis of taeniid antigens using monoclonal antibodies to Echinococcus granulosus antigen 5 and antigen B.

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Appendicitis or perforation as a result of intraluminal foreign body is uncommon. We discuss the implications of the findings in terms of involving close friends in interventions focused on improving the sexual health of African American adolescents. Pigmentation of the skin where the anode needle was inserted occurred in three cases. Transcatheter tricuspid valve-in-valve replacement: one-year results : Alternative to surgery in high-risk patients. The trace impurities were identified using gas chromatography-mass spectrometry (GC-MS) and quantified by gas chromatography with a flame ionization detector (GC-FID). Identification of the substrate and pseudosubstrate binding sites of phosphorylase kinase gamma-subunit. The role of EC processes and a priori expectancy biases in the associative learning of disgust in BII phobia is discussed. The proximal promoter of the bovine luteinizing hormone beta-subunit gene confers gonadotrope-specific expression and regulation by gonadotropin-releasing hormone, testosterone, and 17 beta-estradiol in transgenic mice. This stems not only from the low rate of significant fluorescence, but also from inherent structural properties of these lesions such as color, consistency, and invasion. Control is achieved by coherent manipulation of plasma electrons.

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Incidence rates were computed as average annual rates per 100,000 person years (py). The epithelial cells of the phakomatous choristoma stained positively for S-100 protein and vimentin, the intermediate filament normally found in lens epithelial cells. Lareb Intensive Monitoring is an observational prospective cohort study with no limiting inclusion or exclusion criteria compared with clinical trials. In addition, the PVT1/miR-195 axis can modulate responses of the cancer cells to PTX via regulating EMT. This field study used a qualitative and comparative approach, and the subjects were nursing professors and students. Commutability of the CRM 470 C-reactive protein value in the Dade Behring N High Sensitivity CRP assay. The responsiveness of RLE-6TN, a rat type II cell line, was also compared to primary rat TII cells under the same culture conditions, following exposure to LPS or silica. Environmental tobacco smoke is a recognized factor of morbidity and mortality. Viral respiratory infections and exposure to environmental constituents such as tobacco smoke are known or suspected to trigger wheezing/asthma exacerbations in children. A PCR-SSP method with internal control was established for the detection of the hybrid Rhesus box.

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In this study, we examined whether postnatal taurine administration influences the long-term consequences induced by mild neonatal stressors (10 min maternal deprivation plus sham injection, applied daily to neonatal mice up to 21 days). In vitro study on bone formation and surface topography from the standpoint of biomechanics. Furthermore, it is shown that the interpretation of the one-point function in terms of a stretched-exponential, Kolmogorov-Johnson-Mehl-Avrami result is problematic in the case of correlated nuclei, but that the calculation of higher-order correlation functions permits one to distinguish among various nucleation scenarios. Factor analyses indicate that schizophrenic patients with a family history of psychosis show a pattern of specific neuropsychological deficits, while schizophrenic patients without a family history show a pattern of more consistent cognitive deficits. These results suggest that pyridinylimidazoles and pyrrolobenzimidazoles designed to inhibit human p38 MAPK activation can be developed to treat malaria.

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Periapical lesions are among the most frequent periodontal pathologies in human teeth, generally called apical periodontitis. These properties guide the coordination environment of the transition metal oxide radical that localizes surface holes and is required to oxidize water. 1,5-isoquinolinediol increases the frequency of gene targeting by homologous recombination in mouse fibroblasts. Contribution of the geneextramacrochaetae to the precise positioning of bristles inDrosophila. In order to study whether any level of coupling persists between the ectodermal compartments we injected currents through a microelectrode inserted into one cell of one compartment and monitored its spread by means of a second microelectrode inserted into one cell of another compartment (electrical coupling). Conclusion is made that IFN and IFN inducers may act as regulators of cytokine activity. Interhemispheric interactions between the human primary somatosensory cortices. We analysed indirect cost in terms of absenteeism and unemployment benefits. Half of each pair of dissected long bones was incubated in a chemically defined control medium while the contralateral half was incubated in medium containing PTH or PTH plus the compound to be tested. Peaks for a total of seventeen derivatives of non-protein amino acids were detected by GC-MS.

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Since the tumour interstitial fluid pressure decreased after i.v. Whether the cleavage of proANF in vivo to these ANF peptides occurs during or after its release into the circulation has not been determined. We conclude that ICE provided unique images of the atrial communications and facilitated device closure of secundum ASD and PFO in children and adults. Concentration of cholesterol increases upto 8 day of incubation and later it gradually decreases. Our data show variable degree of concordance between anti-dsDNA IgG ELISAs which may significantly impact inter-laboratory testing as well as the diagnosis and management of SLE patients. Food produced a 5-to 10-fold increase in squirrel density compared with control populations.

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Our findings reveal that the sensitivity to coherence shown by shot noise and skewness, in particular in the limit of large coupling to the drain reservoir, can be used to unambiguously evidence coherent processes involved in charge transport across triple quantum dots. These findings suggest that the apoptotic events by AEPG were associated with the diminished telomerase activity and down-regulation of Bcl-2 expression. HO-1 is induced early after transplantation, whereas Bcl-2 and A20 seem to be induced as part of the chronic response. Data on fetuses with a karyotypic diagnosis of trisomy 21 were collected between January 2002 and March 2010. These findings highlight symptom and cognitive correlates of PEP, and underscore importance of state anxiety in social situations, as well as general anxiety focused rumination in social phobia. Entrapment of Src protein tyrosine kinase in sugar-modified silica. This is a retrospective series of five patients with IVL seen at a single institution over three years. The effectiveness of methods of off-loading to prevent diabetic foot ulcers in adults with diabetes: A Systematic Review. We used single-trial functional magnetic resonance imaging (fMRI) to assess hemodynamic responses to right and left painful stimulation.

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Screening for dihydropyridine calcium channel blockers in plasma by automated solid-phase extraction and liquid chromatography/tandem mass spectrometry. The classical Prader-Willi/Angelman syndrome deletion is flanked by either of the proximal BP1 or BP2 breakpoints and the distal BP3 breakpoint. After 10 courses, laboratory tests had revealed anemia and positive fecal occult blood. Intercellular adhesion molecule-1: a protective haplotype against multiple sclerosis. Intramuscular calcitriol for uraemic children with severe hyperparathyroidism and hypercalcaemia. Controlled insect-sting challenge in 55 patients: correlation between activation of glimepiride tablets ip 2mg uses in bengali plasminogen and the development of anaphylactic shock.

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Interpretation of traditional notification data is complex because classification and reporting systems differ from World Health Organization principles. Oral contraceptives improve endothelial function in amenorrheic athletes. GINS2 regulates matrix metallopeptidase 9 expression and cancer stem cell property in human triple negative Breast cancer. Size distributions of carabids, which are important food items, could not explain the differences in population densities. This dog had a massive accumulation of GM2 ganglioside in the brain. Pharmacological effects of the phytochemicals of Anethum sowa L. Most oral cancers are squamous cell carcinomas rocaltrol medication associated with high mortality. The patient complained of severe eye itching, redness, and epiphora. Pathological correlation in studies of carotid plaque imaging cannot be reliably interpreted or compared because of incomparable and poorly reported histology methods. Cloning of zebrafish metallothionein gene and characterization of its gene promoter region in HepG2 cell line.

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Substitution of placebo for either drug caused raised anxiety and impairment of mental concentration. Here we show that training on visual-verbal paired atenolol 25mg dose associate tasks equivalent to color and shape naming, not involving word reading, leads to strongly asymmetric interference patterns. Fever and cough had begun 24 h earlier, 2 h before she stepped onto a bus for a long-distance trip. Neither lesion affected other components of maternal behavior (pup licking, nest building and nursing). Ninty-six percent of the patients required extraction while one passed spontaneously.

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US Census Bureau data and data from a previous study of diabetes as a cause of death were used to estimate age-, sex-, and race/ethnicity-specific mortality rates for diabetic and nondiabetic populations. One fundamental mechanism used by these complexes is thought to be elocon cost the movement or exchange of nucleosomes to regulate transcription. The public health law of August 2004 between public responsibility and private collaboration. Transformants can then be selected in liquid media or on bacterial plates. Distinction between the literal and intended meanings of sentences: a functional magnetic resonance imaging study of metaphor and sarcasm. Cellular and molecular mechanisms of atherosclerosis with mouse models. The indirect markers of airway hyperresponsiveness, such as AMP or hypertonic saline may more accurately reflect airway inflammation and remodelling than routine symptoms and lung function monitoring.

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Polysynaptic slow depolarization and spiking activity elicited after induction of long-term potentiation in rat auditory cortex. Paraclinoid aneurysms: surgical technique and results in 51 patients. The primary tumors were in the parameningeal sites, extremities, and the perineum, respectively. Treatment consisted of taxol (175 mg/m(2)) given every 3 weeks for three cycles. The higher selectivity of phytosiderophores for Fe(III) over Al(III) facilitates Fe(III) acquisition in alkaline conditions where free Al(III) levels are higher than free Fe(III) levels. We implanted plasmid vectors encoding either BMP-2 or BMP-12 in rats with femur defects, and monitored the bone healing process for 8-weeks. This study shows that administration drug cozaar side effects of a synthetic CB1R agonist results in a biphasic, dose-dependent, effect on hippocampal ACh: a low (0.5 mg/kg, i.p.) and a high (5 mg/kg, i.p) dose of WIN55,212-2 induces a transient stimulation and a prolonged inhibition of hippocampal ACh efflux, respectively. Viral RNA and antigens are increased as much as 20-fold, and culture fluid supernatants from steroid-treated cells contain type B particles with reverse transcriptase.

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The paper considers the basic methodological principles for standardization of environmental carcinogenic agents. A nomogram to predict 5-fluorouracil toxicity: when pharmacogenomics meets the patient. Inhibition of DPP IV restored CTLA-4 surface density to normal and decreased surface expression of CD26 and CD28 on decidual lymphocytes irrespective of stress exposure. Because the correlation between PFS and the superior cerebellar peduncle injury is poorly described in the literature, particularly with regard to relevant radiographic imaging, the authors of this report hope their findings will contribute to that insufficient body of evidence. Total vascular exclusion technique for resection of hepatocellular carcinoma. Our results suggest a completely new mechanism for the low to high confinement mode transition without invoking shear flow or zonal flow. Economic evaluations aim to combine costs and patient outcomes in one analysis. This work developed a single-shot echo-planar imaging-based MR-ARFI method that reduces scan time and ultrasound energy deposition. The availability of the host plants to the herbivores was a function of prior defoliation and environmental conditions.

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The expression of COX enzymes was studied in spinal cords and neuroblastoma cells by western blot. High Correlated Paternity Leads to Negative Effects on Progeny Performance in Two Mediterranean Shrub Species. The two lungs were clear on auscultation, but a systolic cardiac murmur of grade 2/6 could be heard between the 2nd and 3rd intercostal space at the left sternal border. The reported prevalence rates provide policy makers with an up-to-date and more substantiated guideline for the allocation of resources for children and adolescents with MR and PDD. During severe systemic infections it is produced by extrathyroidal tissues. Furthermore, it appears that the syn stereochemistry of the second step requires the phosphate leaving group to serve as the base in catalyzing its own elimination. Studies on the interrelationship of type B and type C virus particles in breast cancer and in leukemia. We developed a suitable system of DNA extraction and real-time quantitative polymerase chain reaction (qPCR) for the specific and sensitive quantification of pathogens and other prilosec heartburn remedy relevant (indicator) organisms in recalcitrant material such as cattle manure. Molecular sieving of red cell membranes during gradual osmotic hemolysis. Intraspecific competition can lead to plastic increase in virulence, likely caused by faster utilization of host resources stimulated by the competitive interactions between the strains.

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