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Calcigard (Nifedipine)

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Calcigard is used to treat hypertension (high blood pressure) and angina (chest pain). Calcigard is in a class of drugs called calcium channel blockers. Calcigard relaxes (widens) your blood vessels (veins and arteries), which makes it easier for the heart to pump and reduces its workload.

Other names for this medication:
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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Calcigard PA 20. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Calcigard and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Calcigard are:

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Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

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Hypocholesterolemic effect of germinated fenugreek seeds in human subjects. Review of a large series of core needle biopsies for invasive carcinomas measuring 0.1 cm or less and correlation of the results with those of subsequent excision. Gas in stems: abundance and potential consequences for tree biomechanics. Epidermal growth factor dependent phosphorylation of a 35-kilodalton protein in placental membranes. The observation of engraftment of human umbilical cord blood-derived hematopoietic stem/progenitor cells in xenotransplanted NOD/SCID mouse model by intra-bone marrow injection. We report the clinical and pathologic findings in one case of mast cell leukemia observed in a series of 60 patients with systemic mast cell disease. Information about the mobility of the water molecules is not yet complete but is crucial for the understanding of the structure of the carbon layers as well as the intercalation process.

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This Protected Block Curriculum approach was chosen to facilitate the learning structure of the curriculum. Enzyme therapy as a physiologically based method of treating acute suppurative diseases of the soft tissues. A cross-fostering design was used to assess the relative involvement of genetic variability and early postnatal experiences on differential levels of playfulness in juvenile Fischer 344 (F344) and Lewis (LEW) rats and the extent to which strain differences in anxiety may influence play in these two strains. Quite often in medical studies multiple discrete indicators are used to measure some characters that are defined only conceptually and are difficult to measure directly. Gut microbiota of an invasive subcortical beetle, Agrilus planipennis Fairmaire, across various life stages. On the other hand, N-CAM 180 was not detected in the unbound fraction, whereas N-CAM 120 and N-CAM 140 were. The overall folding and structure of the domain is similar to that found for Cdc25A. However, genetic crosses with a Mash2 null allele suggested that Eed was not required to maintain Mash2 imprinting, but could be required in a lineage specific fashion to suppress Mash2 expression.

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To evaluate the predictive value of NT-proBNP for 30-day mortality over and beyond the Global Registry of Acute Coronary Events (GRACE) and Thrombolysis In Myocardial Infarction (TIMI) risk scores in patients with NSTE-ACS. Anti-TNF also attenuated the hypothermic effect of high doses of LPS and exacerbated LPS-induced fever. Initial clinical trials have provided encouraging results, including good tolerability and linear pharmacokinetics over a wide dose range. Two patients have demonstrated recurrent arrhythmias despite combination therapy and have undergone repeat epicardial and endocardial ablation. Eye on religion: the reflective physician and the Jewish patient. Effect of thienyl groups on the photoisomerization and rotamerism of symmetric and asymmetric diaryl-ethenes and diaryl-butadienes.

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Activation of mast cells from COX-2 (-/-) mice stimulates the release of PGD(2) during the first 30 min, whereas activation of mast cells from COX-1 (-/-) mice does not generate any PGD(2) in the first 2 h. However, paclitaxel did not have an overall effect on the reinforcing efficacy of morphine assessed over a limited dose range during the course of the repeated self-administration. Better nurse staffing and higher education level mitigated poor patient outcomes among highly vulnerable patients with serious mental illness. The concept that this neoadjuvant chemoradiotherapy regimen improves overall survival has, however, to be proven in a randomized phase III trial. Case-based interprofessional learning for undergraduate healthcare professionals in the clinical setting. Comparative study on the dynamics of the electroencephalographical changes in the petit mal epilepsy during both classical and valproic acid treatment.

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Variation in the group-specific carbohydrate of group A streptococci. A cross-sectional population-based survey of 1,013 middle-aged farmers and 769 matched referents was performed. The author describes his personal reflections over the last 50 years. The first Turkish national standard reference material for penicillin. The second patient, 29-years-old, suffered a transverse fracture at the bases of both corpora cavernosa associated with complete section of the urethra. Optimizing capillary column backflush to improve cycle time and reduce column contamination.

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Prospective study to analyze postpreparation human sperm motility parameters and reactive oxygen species production following antioxidant supplementation. Telomerase is a ribonucleoprotein complex that adds telomeric DNA repeats to the ends of most eukaryotic chromosomes. Asymptomatic recurrences of AF after an apparently successful catheter ablation procedure for symptomatic paroxysmal AF are infrequent. Systemic organization counseling in the hospital: communicating--but properly. The methods were tested on model geometrical solids and on real volume images consisting of a stack of serial sections encompassing entire tobacco BY-2 cells or cell chains. ICU telemedicine improves access artane generic version to high-quality critical care, has substantial costs, and can change financial outcomes. The hydrolytic degradation of the implant-cement interface has to be seen as the main reason for aseptic loosening of cemented total hip replacements. For the latter, both conventional and optimized effective potential (OEP) approaches are used. When PIC is not formed in Deltasgf73, histone H3 is not evicted from the GAL1 promoter. Changes in BMI over three years predict changes in ambulatory and standardized non-physician BPs.

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An update on the management of atherosclerotic carotid artery disease. Autophagy is an intracellular process for vacuolar degradation of cytoplasmic components. Impact of prenatal methylmercury exposure on child neurodevelopment in the Faroe Islands. Successful treatment of a most severe therapy-refractory status asthmaticus by extracorporeal CO2 elimination. Calcium plus vitamin D did not prevent fractures or colorectal cancer in postmenopausal women. Oxidative amide synthesis and N-terminal alpha-amino group ligation of peptides in aqueous medium. The report analyses different types of violence including child abuse and neglect, youth violence, intimate partner violence, sexual violence, elder abuse, self-directed violence, and collective violence. These data from a population of US men with commercial insurance coverage showed a greater resource use burden for patients with primary and secondary hypogonadism compared with similar patients without hypogonadism. Neurodynamics of vascular reactions in hallucination-paranoid form of schizophrenia.

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Based on objective and audited information, the estimated effects of self-reported quality improvement activities were often small and inconsistent. Finally, we evaluated antibody-catalyzed prodrug activation by examining the growth inhibition of human cervical cancer (HeLa) cells with the vitamin B(6) ester of butyric acid. Solid state photochemistry of thymine, its N-methylated derivatives and orotic acids in KBr matrices. This review points to the need to increase the incorporation of complex methodological training, including health services research, the analysis of secondary data and complex survey design in our what is the cost of alprostadil injections doctoral programs, and to provide opportunities for researchers to gain further methodological training. The results indicate that both type I and type II SGCs express all four HCN subunits. Reasons for caution when evaluating health care interventions using non-randomised study designs. Pleomorphic large cell sarcoma of the spleen with rhabdomyosarcomatous differentiation. We propose a new stroke-based algorithm that splits velocity signal into various bands. We show that in the wild-type complex the hinge-helices are formed and the DNA is bent, similar to the symmetric complex.

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Constitutive overexpression of immunoidentical forms of PCP-induced Euglena gracilis CYP-450. Exceptional fermentation characteristics of natural hybrids from Saccharomyces cerevisiae and S. Tongue pressures on the lingual surface of complete mandibular experimental dentures were recorded from mid-line, premolar and molar transducers. Penile prosthesis revision surgery does xanax help alcohol detox is highly successful in providing men with a functional implant. After surgery, combination chemotherapy with cyclophosphamide, vincristine, doxorubicin, ifosphamide, and etoposide was given. Our findings suggest that the two patients in a Chinese family suffering from congenital NDI had a 5,995-bp deletion and 3-bp (GAG) insertion at Xq28. Balance and symmetry of mandibular function is disturbed by loss of continuity of the mandible, which leads to altered mandibular movements and deviation of the residual fragment, as a consequence of which problems with chewing, swallowing, speech, and aesthetics develop. Expression of GFP in these chromosomes is driven indirectly by a Kruppel (Kr) promoter, via the yeast GAL4-UAS regulatory system. Implantation of prosthesis is the most commonly used and effective treatment. These results indicate that components of the icm/dot system and components of the lvh type IV secretion system are able to interact with one another.

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