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Caldikind (Calcitriol)
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Caldikind

Caldikind is a hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give Caldikind.

Other names for this medication:
Actical, Admax, Alcee, Alfabond, Alfacal, Alfacip, Alphadol, Arcium, Aristrol, Biocitral, Bonetuf, Calbec, Calcibest, Calcigra, Caldix, Calsonic, Caltin, Caltive, Caltop, Calvical, Calzem, Cholical, Devita, Dmcal, Kurecal, Laretol, Lctrol, Minroset, Netxod, Nutribone, Osteobel, Ostonex, Ostriol, Primacal, Qpcal, Refirm, Rical, Ritoca, Rockbon, Roical, Rolsical, Romical, Sorvate, Statbone, Trolec

Similar Products:
Dostinex, Imdur, Eulexin, Intagra, Compazine, Mobic, Aurogra

Also known as: Calcitriol

Description

Generic Caldikind is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Caldikind are intestine and bone. Generic Caldikind receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Caldikind may also act on the kidney and the parathyroid glands. Generic Caldikind is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Caldikind has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Caldikind, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Caldikind in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Caldikind produces other independent beneficial effects. Caldikind is also known as Calcitriol. Generic Caldikind treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Caldikind is Calcitriol. Brand name of Generic Caldikind is Caldikind.

Dosage

Generic Caldikind is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Caldikind suddenly.

Overdose

If you overdose Generic Caldikind and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Caldikind are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

If you are taking a dietary supplement without a prescription, carefully read and follow any precautions on the label. For these supplements, the following should be considered:

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This technique is an important addition to the breast conservation surgery algorithm. Thus, the complete viral growth cycle, including production on infectious virus, was demonstrated in the HPV 59 immortalized cells grown in a simple culture system. Converging findings from pharmacological and imaging studies support the hypothesis that a state of hyperdopaminergia, specifically elevations in D2/3 receptor availability and a hyperactive reward processing network, underlies mania. gamma-Tocopherol induced apoptosis in androgen-sensitive LNCaP but not androgen-resistant PC-3 cells. Reference values and early determinants of intra-abdominal fat mass in primary school children. The surviving neonate had normal development without obvious sequelae during a follow-up period of 1 year.

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With such continuous therapy, sequentially appearing peaks of systemic mediator overflow may be attenuated and persistently high plasma levels reduced. Effect of free magnesium and salts on the inorganic pyrophosphatase purified from a slightly halophilic Vibrio alginolyticus. In recent years, studies from several groups have challenged the traditional dogma and demonstrated that monoclonal antibodies can modify various aspects of mycobacterial infections. Adolescent brain development: a period of vulnerabilities and opportunities. Hepatocytes preincubated for 24 h in the presence of metformin at clinically relevant concentrations showed impaired glycogenesis as well as gluconeogenesis.

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Light, but not heavy alcohol drinking, stimulates paraoxonase by upregulating liver mRNA in rats and humans. Studies on the time frame for ossification of the medial clavicular epiphyseal cartilage in conventional radiography. Experiments in fragmentation indicate the position of the primordia of individual parts of the leg in the disc. It has been nearly 20 years since sarcoidosis mortality was examined at the population level in the United States. Moreover, the role of p55 in the provocation of corticosterone release engendered by lipopolysaccharide (LPS) and psychogenic stressors (noise or restraint) was also determined. At thermal equilibrium, hydrogen bonds are formed at low temperature and are broken at high temperature. The methods and processes used in the development of this statement were similar to those used for other extensions of the STROBE statement. Confirmation of the presence of cyclic AMP in lettuce seeds, var. We next evaluated the degradation of these antigens in denervated muscle during a temporal study. The C2 domain is one of the most frequent and widely distributed calcium-binding motifs.

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Identification of a promoter element which participates in cAMP-stimulated expression of human insulin-like growth factor-binding protein-1. Pericardial involvement includes acute and chronic pericardial disease and pericardial effusion. The specific activities of selected deep-sea and terrestrial acetonitrile-grown bacteria against a suite of nitriles and amides were higher than those of the only other reported marine nitrile-hydrolysing R. The platelet agonists listed above induced an increase in pp60c-src phosphorylation at Ser-12, which is the amino acid phosphorylated by protein kinase C. Topology analysis revealed that mature AIF is a type-I inner membrane protein with the N-terminus exposed to the matrix and the C-terminal portion to the intermembrane space. However, those unfortunate few in these countries who do develop cancer, despite a robust microphage/NO system, must be presumed to have a markedly virulent tumor development micro-environment (e.g., activation of tumor promotion genes, inactivation of tumor suppression genes, multiple mutations, etc.) that escapes even the particularly alert immune surveillance--thence the earlier (by about a decade) death by cancer in those countries. FK 506: a novel immunosuppressant for treatment of autoimmune disease. Analysis of the distribution of the alpha 6 and beta 1 integrin subunits in the gradients showed that they migrate as a large complex after extraction of cells with octylglucoside, but not after Triton X-100 extraction. The functional adaptation of skeletal muscle are dependent on a multitude of factors, which at the present time are not completely understood.

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Permanent pacemaker insertion after CoreValve transcatheter aortic valve implantation: incidence and contributing factors (the UK CoreValve Collaborative). The significance of the personality traits of schizophrenic patients and their therapists for the therapeutic relationship. These data demonstrate a hierarchal relationship whereby transient Hand1 septum transversum expression defines epicardial precursors that are subsequently dependent on Hand2 function. Concentration of ptaquiloside, a major carcinogen in bracken fern (Pteridium spp.), from eastern Australia and from a cultivated worldwide collection held in Sydney, Australia. The possibility that the CTD of the largest subunit of RNA polymerase II is a substrate of Ssu72 is discussed. Impact of comprehensive pulmonary rehabilitation on anxiety and depression in hospitalized COPD patients. Comparison of this spectrum with the spectrum obtained with the corresponding synthetic 6-hydroxy-alpha-methylnorepinephrine, however, ruled out this possibility. Oxidative stress usually happens when cells are exposed to more electrically charged reactive oxygen species (ROS) such as H2O2 or O2-. Norgestrienone, a possible therapeutic agent in hereditary angioneurotic edema. A single high dose of streptozotocin was found to cause a transient increase in islet capillary permeability 2-4 h after administration.

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Alpha-gamma hybrid peptides that contain the conformationally constrained gabapentin residue: characterization of mimetics of chain reversals. We measured plasma concentrations of cardiac troponin I and free fatty acids, cardiac function as assessed by transesophageal echocardiography, glycogen content, glycogen synthase activity, and the expression of AMP-activated protein kinase (AMPK) and protein kinase B (AKT) in cardiomyocytes. Health effects of metoprolol in epibenthic and endobenthic invertebrates-A basis to validate future in vitro biotests for effect-based biomonitoring. Resistance to powdery mildew fungi that result from mutations in host genes promises to shed light on mechanisms that are required for the establishment of disease susceptibility. Neuromyelitis optica in a child with atypical onset and severe outcome. Southern Africa ports as spaces of HIV vulnerability: case studies from South Africa and Namibia. The main objective of this study was to synthesize novel demulsifiers for resolving oil-in-water emulsions. Generation of Arabidopsis protein chips for antibody and serum screening. Multiple color immunofluorescence for cytokine detection at the single-cell level. For rapid in vitro selection, three assays (establishment of sensitivity curves for embryogenic calli, determination of lethal doses for seed germination, and a rapid screening of cut young leaves based on the colour change of the medium) were established.

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The increase in active sites in N-doped Co3O4 nanosheets and improved electronic conductivity with N doping and oxygen vacancies results in excellent electrocatalytic activity for the OER. Additionally, we surprisingly found that BMSCs and PMSCs could directly form tubular structures in vitro on Matrigel and their conditioned medium showed significant proangiogenic bioactivities on endothelial cells in vitro compared with those of AMSCs and UMSCs. This paper reports research on the effects of variations in injection velocity and permeability on the heat transfer and flow through a highly porous medium between two horizontal parallel plates situated at constant distance with constant suction by the upper plate. After years of questionable applications of law reform in Japan it is imperative that critical self-assessment be done to give proper meaning to both the spirit and rule of mental health law in Japan. Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity. The definitive remission of the syndrome may occur in the first years of onset, although in most patients the febrile episodes continue with an increase of free intervals and attenuated symptoms, and full recovery in prepuberty or adolescence with no sequelae. Certain health care, family, and community disparities were more often reported among children with MBDDS than among children without MBDDs in rural and urban areas. This case report discusses two cases in which patients present with the uncommon triad of extremity pain, focal periosteal reaction on imaging studies, and intramuscular hemangioma on pathologic examination. Interestingly, cleavage of pVIII at both potential cleavage sites appears essential for the production of stable BAdV-3 virions as BAdV-3 expressing pVIII containing a glycine-to-alanine mutation of either of the potential cleavage sites is thermolabile, and this mutation leads to the production of noninfectious virions.IMPORTANCE Here, we demonstrated that the BAdV-3 adenovirus protease cleaves BAdV-3 pVIII at both potential protease cleavage sites.

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Clinical Characteristics and Outcomes of Patients With Cellulitis Requiring Intensive Care. This systematic review and meta-analysis investigates the relationship between cancer outcomes and both vitamin D-related genetic variation and circulating 25-hydroxyvitamin D (25OHD) concentration. Nine nephrology and 7 cardiology faculty members, each paired with a senior clinical fellow from the discipline, were surveyed. Healthy subjects carrying the BANK1 risk haplotype were also characterized by an expansion of memory B cells. Role of scientific organization of practical training in optimizing the educational process. Public and health-care professionals must be equipped with necessary knowledge to combat stigma, discrimination, social and structural inequalities, and misconceptions associated with orofacial cleft. Indeed, a portion of the contraction arises from central mechanisms, whereby spinal motoneurons are recruited through the evoked sensory volley.

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Since carbohydrate recognition is involved in numerous biologic processes, including skin regeneration, the aim of this study was to identify sugar receptors expressed at the surface of human dermic and epidermic cells. Orders written by medical house staff covering the study units between January 8 and March 10, 2001, were collected daily and evaluated for obvious prescribing errors, the type and significance of the errors, and the number of hours the resident had worked during a 24-hour shift at the time of the prescribing error. The pattern of associations between maternal phosphoglucomutase locus 1 (PGM1) and foetal macrosomia in diabetic pregnancy has been compared with that observed in normal pregnancy. Porcine circovirus type 2 was detected by PCR in all tissue samples except in those of valium 10 mg sleeping pills the control piglets. The two products examined were Mercon vap liquid in a stock jar and the Mercon tainer dry jar system. Socio-demographic, clinical and lifestyle characteristics were recorded for the study participants.

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In this study we tested the involvement of V1 in the perception of moving phosphenes by applying transcranial direct current stimulation (tDCS) to this area. Both pathways share the terminal insertion of channels into target membranes, and unique esterases have been postulated to participate in the activation of cytolytic effector molecules. Triple or quadruple clamping has been suggested to control haemorrhages, but the risk of the heart running dry has warranted internal shunts which have only been successful in odd cases. They were found to bind to the same or a very similar region on the surface of the trileptal 600mg tab enzyme. Using a model-based estimation, Disability Adjusted Life Years (DALYs) were calculated on the basis of the prevalence of STIs. Fibro-inflammatory polyp associated with superficial stomach cancer. The survival rate for acute hepatic failure induced by Propionibacterium acnes and lipopolysaccharide (LPS) was increased when a hot water extract from the flowers of Inula britannica L.

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Many identified and yet unknown factors contribute to the pathogenesis of inflammatory bowel disease (IBD). To determine the effects of electrical stimulation (ES) on oxygen uptake (VO(2)) kinetics and delta efficiency (DE) during gradual exercise. The inhibition of this histamine release by the addition of the idiotype (290A-167) confirmed the specificity of the reaction. These morphological criteria correlate in general with the clinical course of patients suffering from bladder cancer. In this study we designed a modified method of abdominal aortic constriction (AAC) in order to establish a stable animal model of left ventricular hypertrophy (LVH). Diabetic Microvascular Disease and Pulmonary Fibrosis: The Contribution of Platelets and Systemic Inflammation. A DSM-III-R diagnosis of alcohol dependence and a measure of lifetime problem drinking served as the 30-year outcome variables.

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In our study irritant pesticides (Fusilade S, Karathane LC) and a technical pesticide component (Trend) were tested and their effects on the tissue structures of CAM were examined. At the end of the hospital stay, neuropsychological deficits persisted. DC-SIGN, a C-type lectin exclusively expressed at the cell surface of DC, functions as an adhesion receptor facilitating T cell binding and priming through recognition of glycosylated ICAM-3 on naive T cells. These elastomers also show promise for other cardiovascular pathologies where NO-based therapies could be beneficial. The steady state properties of the model are demonstrated analytically. Mapping spatial proximities of sulfhydryl groups in proteins using a fluorogenic cross-linker and mass spectrometry. In spite of the realization of their importance, however, the connections between fluctuations and function have largely been empirical, even when they have been quantitative. We proposed development of an intramedullary device for ankle arthrodesis which spared the subtalar joint using a sinus tarsi approach. Frequent recurrences of these tumours have often been described. pH profiles of proline transport with membrane vesicles from Mycobacterium phlei with artificial and natural electron donors.

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A novel procedure for Roux-en-Y reconstruction following laparoscopy-assisted distal gastrectomy: transoral placement of anvil and intracorporeal gastrojejunostomy via umbilical mini-laparotomy. Simultaneous administration of hepatitis B and yellow fever vaccines. On immunohistochemical analysis, osteoclastic giant cells were reactive for CD68 and vimentin confirming histiocytic/mesenchymal derivation whereas pleomorphic giant cells and mononuclear cells were reactive for cytokeratin which proved their epithelial nature. Determination of CH4, CO2 and N2O in air samples and soil atmosphere by gas chromatography mass spectrometry, GC-MS. The ability to adapt to host quality changes is necessary particularly if the mobility of an animal is poor or risk-constrained. Zymographic and immunological studies revealed that primarily tissue-type plasminogen activator and to a lesser extent urokinase-type plasminogen activator were present in fluids of pemphigus vulgaris (type Neumann) skin blisters. An analysis of some aspects of synaptosomal ultrastructure by the use of serial sections. Short-term T cell receptor directed immunotherapy induces organ specific peripheral tolerance in a strongly incompatible rat model. In the current study we found that menopausal symptoms were reduced similarly by LD and SD, however for the combined treatment of menopausal symptoms and osteoporosis the standard dosage of 644 mg/day of Femarelle is needed. The pharmaceutical properties, including the physical and chemical properties, and the bioavailability are greatly influenced by their polymorphism.

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Factors of effects on transformation behaviors of inorganic mineral matters in desulfurizing process of burning coal. Dielectric properties of micellar aggregates due to the self-assembly of thermoresponsive diblock copolymers. Comparison of the EI/BMR ratio with the Goldberg statistical cut-off allowed us to detect individuals who were low energy reporters (LERs). The growth of PA educational programs in US medical education-stimulated by grants, public policy, and anticipated shortages of providers-has gone through 3 distinct phases. Administration of an AQP1 and 4 antagonist, AqB013, non-significantly increased brain water content in sham, non-injured animals, and did not prevent edema formation 24 h after trauma in either the parietal cortex or hippocampus. K16, a type I keratin, is upregulated in hyperproliferative states including psoriasis. Lack of evidence for association of high altitude pulmonary edema and polymorphisms of the NO pathway. These infants had velocity waveforms different from those of healthy infants, but also were totally different from the characteristic brain death pattern of older children. Prognostic impact of CK-20-positive cells in peripheral venous blood of patients with gastrointestinal carcinoma. The urogenital injuries with rupture of the bladder, the urethra and the vagina led despite immediate urological management to an incontinence, which finally required definitive urine drainage via an ileum conduit.

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The guidelines take into account the balance between benefits and harms, the evidence quality, cost and resource use implications, and patient values and preferences. We have investigated the convergence speed of this SOM and Dynamic Link Matching (DLM) on a benchmark problem for the solution of which both algorithms are good candidates. Numerical simulations suggest that oscillations occur in a realistic range of reaction rates and concentrations. Research is ongoing to determine the effects of higher doses of fexofenadine. The method of biliary tracts drainage of patients with biliodigestive anastomosis at obstructive jaundice and acute cholangitis. Although both individually also enhanced IGFBP-4 mRNA levels in ER-positive T47D cells, their effect in combination was antagonistic in this cell line. Description of the circulation by William Harvey (1578-1657) in 1628 marks the beginning of biaxin antibiotic classification the changes that ensued.

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The Use of Latex Catheters to Close Enterocutaneous Fistulas: An Institutional Protocol and Retrospective Review. Misclassification of occupational disease in lung transplant recipients. Increased monoamine metabolism in experimental herpes simplex virus (HSV) encephalitis is well established. Immaturity at delivery and monochorionicity are more common in pregnancies complicated by fetal demise. This causes an almost exclusive lysis of the clot without alterations of systemic coagulation. The aim of the review was to synthesise the best available evidence on the economic feasibility of canine-assisted interventions on the health and social care of the older population residing in long term care. Clear cell and endometrioid carcinomas may be unique histological types compared with serous carcinomas with respect to stage distribution and association with endometriosis.

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We further demonstrate, by using synthetic data, that a Kohonen Net is capable of forming topological maps of signals of different intensity, where an adjacency relationship is maintained both among the signals of the same frequency composition at different intensities and between signals of different frequency compositions at the same intensity. Safety of intranasal Bevacizumab (Avastin) treatment in patients with hereditary hemorrhagic telangiectasia-associated epistaxis. We compare our new concept with the classic reflex concept in a theoretical approach, by implementing both concepts into simple postural control models. There will always be an inherent risk to participation in contact sports. Similarly inhibition of protein kinase A (PKA) or protein kinase C (PKC) was also without effect. These drugs may be classified based on the site of their action. In 19 pts we found pathologic left heart wall motions established by laevocardiography by applying the half axis method. The authors report their experience in choosing the surgical treatment for early gastric cancer. Drugs active in this regard include inhibitors of the renin-angiotensin system, calcium channel blockers, and beta-blockers. A glycoprotein in the accessory cell of the echinoid ovary and its role in vitellogenesis.

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Outcome measures were being in the worst quintile of scores for, respectively, the Philadelphia geriatric morale scale and will oral lamisil cure yeast infection four dimensions of functioning from the sickness impact profile (home management, mobility, self care, and social interaction). Glycose chain extension of the first heptose residue (HepI) influenced the nature of the C4b-LOS linkage. Histological evaluation of tonsils indicated that CUL1 protein expression was relatively specific for maturing germinal centers. Despite gains in QALY and PFS, the addition of B to single agent CT for treatment of platinum-resistant recurrent ovarian cancer is not cost effective. Correlation between aberrations and absorbed doses of x rays measured by thermoluminescence dosimeters is shown, as well as correlation between chromosomal lesions and damaged cells and the frequency of chromosomal aberrations. Dasm1: a receptor that shapes neuronal dendrites and turns on silent synapses?.

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The number of monodendritic neurons is higher in the vermal than in the hemispheric part of the lobulus (lobulus VII) and is higher in lobulus X than in lobulus VII of the vermis. The p14 N-terminal sequence ((1)VLERTXA(7)-) is identical to the region 99-103 residues of the human MHC class II antigen DQ-beta chain. With follow-up periods ranging from 4 to 8.4 years (mean, 6.3 years), aortoaxillary bypass grafts were patent in all patients. This technique produces discomfort, inconvenience and interference with daily activity. Diversity and distribution of alpha satellite DNA in the genome of an Old World monkey: Cercopithecus solatus. Regionalization of Cystectomy: Importance of Care Coordination, Bundled Payments and Surgical Ownership. Over the last 15 years, there has been remarkably rapid progress in defining the molecular basis of inherited disorders. Some laboratories, including our own, find that survival following ionizing irradiation of fibroblasts is within the normal range, other laboratories find an abnormal decrease in cell survival. All IFN-gamma actions are initiated by binding to high affinity cell surface receptors, which are constitutively expressed in virtually all cell lines from various tissues. We prove that a neural network, iterated sequentially, admits an energy if and only if the weight matrix verifies two conditions: the diagonal elements are non-negative and the associated incidence graph does not admit non-quasi-symmetric circuits.

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