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Calmef (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Calmef, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Calmef is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alflux, Alpaz, Alpranex, Alpron, Alzokam, Alzopax, Anxicalm, Depser, Enxolam, Mebasap, Paxor, Prolam, Propnix, Prozam, Prozolam, Rivcam, Serxanti, Sinzolam, Somnarest, Suzilam, Tenscure, Tensyl, Tranisol, Xerodep, Zolipax, Zomark, Zopain

Similar Products:
Naprosyn, Trandate, Zyrtec, Arimidex, Clarinex, Viramune

Also known as: Alprazolam


{name} XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

{name} XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

{name} XR may also be used for other purposes not listed in this medication guide.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Calmef. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


If you have been prescribed Calmef for medical reasons, the best way to avoid a Calmef overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Calmef consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Calmef XR dosage information

Side effects

The most common side effects associated with Calmef are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of alprazolam in the pediatric population. Safety and efficacy have not been established.

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Benign familial neonatal convulsion (BFNC) is a rare autosomal dominant disorder caused by mutations in two genes, KCNQ2 and KCNQ3, encoding for potassium channel subunits underlying the M-current. Expression of cyclooxygenase (COX)-2 plays a key role in tumorigenesis and development and peroxisome proliferator-activated receptor gamma (PPARgamma) has been implicated in the control of COX-2 expression in some tissues. The accuracy of the indirect digital system was better than cone beam system, and this difference was statistically significant. Our findings can have a bearing on the question of the evolution of this major human polymorphism and human life history. The signal pathways activated by anticancer drugs are classified as death receptor (DR) -dependent or -independent. During this period, adult, yearling and juvenile marmots selected diets consistent with the predicted goal of energy maximisation. After injecting agarose into these brains at different depths, we compared both the conventional ultrasonographic images and the elastographic images of the region of interest with the corresponding anatomical brain sections. The quality of movements was described using Laban Movement Analysis (LMA). The clinical severity of GOR was significantly increased in eight patients and fundoplication was required in five. Leaf and shoot growth were not correlated with coccid infestation but shoot vigour (leaf to green shoot ratio) declined significantly with increasing btd-class (or age).

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In our study, we evaluated the performance of the model in Chinese patients with acute stroke. Spiders of the genus Cupiennius Simon 1891 (Araneae, Ctenidae) : I. We also show that upon tyrosine phosphorylation, p52shc becomes associated with the adaptor protein, Grb2. Long-term monitoring of insulin-like growth factor I in adult growth hormone deficiency: a critical appraisal. We report on findings from the Contraceptive Use, Pregnancy Intentions and Decisions (CUPID) survey of young Australian women, a large-scale longitudinal study of 3,795 women aged 18-23 years. A model has recently been proposed that ascribes to the so-called LCM, a central role in the building up of the phycobilisome, in addition to its role of terminal energy acceptor (Capuano, V., Braux, A.-S., Tandeau de Marsac, N., and Houmard, J.

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Genomic nurse experts reviewed recent literature and consumer resources to elucidate updates in technology through the lens of the genetically vulnerable patient and family. Galanin-like immunoreactivity in extrinsic and intrinsic nerves to the gut of the Atlantic cod, Gadus morhua, and the effect of galanin on the smooth muscle of the gut. Incarcerated Spigelian hernia (SH) is an uncommon surgical emergency that demands immediate operative treatment. Seventy-three isolated ACL-injury patients (20 women and 53 men) were compared with 51 control group patients (19 women and 32 men). Reithrodontomys megalotis was live-trapped on three open field grids in eastern Kansas from August 1979 to August 1982. In 2001, an experiment carried out at Cattenom Power Plant during a unit outage in the presence of a leaking fuel cladding, based on measurement of alpha-emitting radioactive elements, made it possible to determine a realistic particle resuspension coefficient. This technique offers excellent local tumor control and minimal patient morbidity, allowing for immediate use of systemic chemotherapy and/or conventional radiation if indicated.

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Since the mortality of AKI requiring renal replacement therapy (RRT) is greater than half in the intensive care unit, a better understanding of the potential of RRT to improve outcomes is urgently needed. It is important to audit mortality data on a regular basis as this can provide valuable insight into hospital practice and may help to identify preventable causes of mortality. Its main problems include duration of the procedure and, in particular, the vascular staple size and associated difficulties with the vascular anastomosis suturing. In contrast, BLM was not detected in any lymph nodes when BLM-SOL was administered. Acupuncture has traditionally been used in China and is being increasingly applied in Western countries to treat a variety of conditions, including inflammatory disease. Development of pharmacophore models for small molecules targeting RNA: Application to the RNA repeat expansion in myotonic dystrophy type 1. To evaluate the effects of the National Essential Medicine Policy (NEMP) on outpatient service utilization and expenditure in Tianjin, China. Multichannel electrochemiluminescence of luminol in neutral and alkaline aqueous solutions on a gold nanoparticle self-assembled electrode. Using as little as 200 microCi of 99m-Tc per patient, in vivo human immune clearance can be determined with a minimal radiation biohazard.

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Factors affecting solubility of calcium lactate in aqueous solutions. Morphine only induced histamine and tryptase release from HSMC, but not the de novo synthesis of PGD2. Thermoreversible photocyclization of a pyrazolotriazole to a triazasemibullvalene: a novel electrocyclic reaction. The kinetics of oxidation of reduced cytochrome c by ferricyanide derivatives. Administration of rIL-12 to IRF-1(-/-) mice restores normal expression of LTbeta and IFN-gamma, and significantly enhances the ability of IRF-1(-/-) mice to resist MNU-induced pathogenesis. Pulmonary manifestations with radiological changes on chest X-ray and CT can be seen in DRESS.

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The effect of local anaesthetic agents on lipolysis by human adipose tissue. Replacement of defects of the jawbones is one of the rapidly developing fields of maxillofacial surgery. Reversed sexual size dimorphism (RSD, females larger than males) is commonly found in birds of prey. Clinical laboratories collaborate to resolve differences in variant interpretations submitted to ClinVar. The relation between genetic counseling and the procreation sphere among the studied families is presented.

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This plant-derived antibody was obtained from different batches of 100-200kg of tobacco leaves and coupled to Sepharose CL-4B with high efficiency. were separated from each other and reassembled with either the same (controls) or opposite polar orientation. Differentiation of HL-60 myeloid leukemia cells induced by all-trans retinoic acid is enhanced in combination with caffeic acid. To investigate the relationship between the activity of pyruvate dehydrogenase (PDH) bypass and the production of pyruvate of a multi-vitamin auxotrophic yeast Torulopsis glabrata. Microscopically, transepithelial elimination of elastic fibers was specifically observed in keratoacanthomas. Our study supports previous research that has documented a high mortality rate among patients with invasive zygomycosis, especially among those with an underlying haematological malignancy, and the need for a rapid initiation of an effective antifungal treatment. R5 to X4 switch of the predominant HIV-1 population in cellular reservoirs during effective highly active antiretroviral therapy. Angioscopic quality assessment is a valuable adjunct to exclude endoluminal disease most commonly occurring in the median cubital vein.

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Human embryonic myogenic precursors were transplanted into muscles of mdx mice with hereditary dystrophin-deficient muscular dystrophy. Based on preclinical data, we hypothesized that the protein kinase C (PKC) iota inhibitor, auranofin (a gold salt used for other pain conditions), palliates this pain. Whenever requirements change data acquisition and handling of signal analysis have to be adapted or even completely new structured, especially in real-time applications. Each module has a line process which interprets whether a given edge is derived from a reflectance or illuminant change based on prior knowledge of shadows: it is mainly luminance that changes at the boundry of a shadowed area. Asymmetric dimethyl arginine and myeloperoxidase may be critical mediators of the endothelial damage that results from oxidative stress. Effect of resin viscosity and enamel beveling on the clinical performance of Class V composite restorations: three-year results.

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Synapse organization and modulation via C1q family proteins and their receptors in the central nervous system. This description reflects the inherently stochastic nature of gene expression, known to be a major factor in the heterogeneous response of individual cells within a clonal population to an inducing stimulus. We incorporated this targeted PEGylated lipid into lipoplexes using two strategies of formulation, i.e., using levaquin dose iv either preformed micelles or liposomes. TAM-67, a mutant of c-Jun that lacks the N-terminal transactivation domain of c-Jun, also enhanced COX-2 promoter activity and protein expression in cells treated with EGF. The significance of this difference on the conception rate remained unsolved, however. The deduced amino acid sequence of the Mycoplasma Enzyme I shows that it differs from other Enzymes I by having fewer acidic amino acids and more basic, amidated, and aromatic amino acids. In contrast to the perfect fluid case, where the vorticity tends to a well defined stationary state, complete relaxation towards an equilibrium state is not observed in numerical simulations of quasigeostrophic decaying turbulence. The effect of cyclin D expression on cell proliferation in human gliomas.

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The effects of nurse staffing on adverse events, morbidity, mortality, and medical costs. The column studies and injection-withdrawal experiment indicate that chromium ultram gel has the potential to leach from aquifer sediments and act as a secondary source of contamination. Stimulated Thy-1 and Ly-1-positive cell populations proliferated in the medium supplemented with both interleukin-1 (IL-1) and interleukin-2 (IL-2). Increased cfPWV and carotid stiffness were defined according to either international reference values or the 90th percentile of a local control group (110 age and sex-matched healthy individuals). Four-dimensional computed tomography (4D CT) can provide patient-specific motion information for radiotherapy planning and delivery.

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The results are good for pain, articular movement and the consolidation of the allograft host bone junction. Celastrol inhibits dengue virus replication via up-regulating type I interferon and downstream interferon-stimulated responses. A retrospective review of large, multicenter adult spinal deformity (ASD) database. In Experiment 1, we dissociated these two variables by asking participants to report each encoding angle using two different responses: by turning to walk on a path parallel to the initial facing direction in the same (reproduction) or opposite (supplementary angle) direction. The NF-kappa B/Rel family is a growing class of transcriptional regulators whose members share the conserved Rel-homology domain, involved in specific DNA binding and dimerization.

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As found light- and electron microscopically and also histochemically, glycogen and lipids are stored in both cells. Intraluminal administration of SCFAs (100-200 mM) into the proximal colon significantly accelerated colonic transit. Proapoptotic activity in vitro of two novel ruthenium(II) complexes with flavanone-based ligands that overcome cisplatin resistance in human bladder carcinoma cells. Age impacts smile perception based on maxillary gingival display and the presence of a black triangle between the maxillary central incisors, but not of the incisal edge position of the maxillary central incisors. The response, measured in terms of seven characteristics (winter bud weight, winter bud nitrogen and phosphorus content, flowering frequency, total seed weight, seed number and weight per seed), was analysed. These findings are consistent with the hypothesis that there may be a time-related therapeutic window in the treatment of physical impairment associated with poststroke depression.

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Medicare Annual Wellness xanax drug card quizlet Visits: How to Get Patients and Physicians on Board. A close link between smoking and depression has been documented by research primarily based on U.S. Adaptive Automation Triggered by EEG-Based Mental Workload Index: A Passive Brain-Computer Interface Application in Realistic Air Traffic Control Environment. Although clozapine therapy is associated with a number of adverse drug reactions, it is frequently used. physical functioning, comorbidity, medication compliance and perceived cardiac severity).

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