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Calmnir (Clonazepam)
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Calmnir

Calmnir is one of the products that belong to the bensodiazepine group and have a strong sedative effect. It is widely used among people with severe panic attacks and anxiety caused by depression treatment. Thanks to its unique features, Calmnir helps to stop convulsions and epileptic seizures.

Other names for this medication:
Almac, Alrest, Anxiset, Azpax, Catier, Clonark, Clonasig, Clonatrac, Clonax, Clonoasig, Clonopam, Clopam, Clotweet, Cloze, Convaclon, Easyfeel, Eminaz, Epicloz, Epitril, Epizam, Escimax, Escitapax, Esitor, Estalonix, Jasoclam, Jbcloz, Lonazep, Lonipax, Lozep, Melzap, Nazee, Nexclo, Norep, Nozim, Nupam, Ozepam, Repam, Somnolex, Ubitpam, Zepamax, Zeptril, Zozep

Similar Products:
Tofranil, Loxitane, Geodon, Trandate, Epivir

Also known as: Clonazepam

Description

Calmnir, like other benzodiazepines, while being a first-line treatment for acute seizures, is not suitable for the long-term treatment of seizures due to the development of tolerance to the anticonvulsant effects.

Calmnir has been found effective in treating epilepsy in children, and the inhibition of seizure activity seemed to be achieved at low plasma levels of Calmnir. As a result, Calmnir is sometimes used for certain rare childhood epilepsies; however, it has been found to be ineffective in the control of infantile spasms. Calmnir is mainly prescribed for the acute management of epilepsies. Calmnir has been found to be effective in the acute control of non-convulsive status epilepticus; however, the benefits tended to be transient in many of the people, and the addition of phenytoin for lasting control was required in these patients.

It is also approved for treatment of typical and atypical absences, infantile myoclonic, myoclonic and akinetic seizures. A subgroup of people with treatment resistant epilepsy may benefit from long-term use of Calmnir; the benzodiazepine clorazepate may be an alternative due to its slow onset of tolerance.

Dosage

Adults. The initial dose for adults with seizure disorders should not exceed 1.5 mg/day divided into three doses. Dosage may be increased in increments of 0.5 to 1 mg every 3 days until seizures are adequately controlled or until side effects preclude any further increase. Maintenance dosage must be individualized for each patient depending upon response. Maximum recommended daily dose is 20 mg. The use of multiple anticonvulsants may result in an increase of depressant adverse effects. This should be considered before adding Calmnir to an existing anticonvulsant regimen.

Pediatric Patients. Calmnir is administered orally. In order to minimize drowsiness, the initial dose for infants and children (up to 10 years of age or 30 kg of body weight) should be between 0.01 and 0.03 mg/kg/day but not to exceed 0.05 mg/kg/day given in two or three divided doses. Dosage should be increased by no more than 0.25 to 0.5 mg every third day until a daily maintenance dose of 0.1 to 0.2 mg/kg of body weight has been reached, unless seizures are controlled or side effects preclude further increase. Whenever possible, the daily dose should be divided into three equal doses. If doses are not equally divided, the largest dose should be given before retiring.

Geriatric Patients. There is no clinical trial experience with Calmnir in seizure disorder patients 65 years of age and older. In general, elderly patients should be started on low doses of Calmnir and observed closely.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, or coma.

Storage

Tablets should be kept at room temperature, between 15 C and 30 C (59 F and 86 F).

Side effects

The most common side effects associated with Calmnir are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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