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Capscare (Capecitabine)
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Capscare

Capscare is used in combination with other medications to treat breast cancer that has come back after treatment with other medications. It is also used alone to treat breast cancer that has not improved after treatment with other medications.

Other names for this medication:
Capecitabine, Capegard, Capehope, Capget, Capiibine, Capres, Capscare, Captabin, Capxcel, Distamine, Naprocap, Xabine, Xelocel

Similar Products:
Lexapro, Panadol, Cozaar, Parlodel, Trandate, Epivir, Estrace, Dulcolax, Lipitor

Also known as: Capecitabine

Description

{name} (capecitabine) is a cancer medicine that interferes with the growth of cancer cells and slows their spread in the body.

{name} is used alone or in combination chemotherapy to treat colon cancer, breast cancer, or colorectal cancer.

{name} is sometimes used when cancer has spread to other parts of the body (metastatic).

Dosage

Usual Adult Dose of Capscare for Colorectal Cancer:

MONOTHERAPY: For first line treatment of patients with metastatic colorectal carcinoma when treatment with fluoropyrimidine therapy alone is preferred: -RECOMMENDED DOSE: 1250 mg/m2 orally 2 times a day (morning and evening; equivalent to 2500 mg/m2 total daily dose) for 2 weeks followed by a 1 week rest period given as 3 week cycles ADJUVANT TREATMENT IN PATIENTS WITH DUKES' C COLON CANCER: -RECOMMENDED DOSE: 1250 mg/m2 orally 2 times a day (morning and evening; equivalent to 2500 mg/m2 total daily dose) for 2 weeks followed by a 1 week rest period given as 3 week cycles for a total of 8 cycles (24 weeks) Comments: -The tablets should be swallowed whole with water within 30 minutes after a meal. Use: Colorectal Cancer: -As monotherapy for adjuvant treatment in patients with Dukes' C colon cancer who have undergone complete resection of the primary tumor when treatment with fluoropyrimidine therapy alone is preferred; this drug was non-inferior to 5-fluorouracil and leucovorin (5-FU/LV) for disease-free survival (DFS); physicians should consider results of combination chemotherapy trials, which have shown improvement in DFS and OS, when prescribing this drug as a single-agent in the adjuvant treatment of Dukes' C colon cancer -As first-line treatment of patients with metastatic colorectal carcinoma when treatment with fluoropyrimidine therapy alone is preferred; combination chemotherapy has shown a survival benefit compared to 5-FU/LV alone; survival benefit over 5-FU/LV has not been demonstrated with this drug as monotherapy; use of this drug instead of 5-FU/LV in combinations has not been adequately studied to assure safety or preservation of the survival advantage

Usual Adult Dose of Capscare for Breast Cancer:

MONOTHERAPY: -RECOMMENDED DOSE: 1250 mg/m2 orally 2 times a day (morning and evening; equivalent to 2500 mg/m2 total daily dose) for 2 weeks followed by a 1 week rest period combined with docetaxel 75 mg/m2 as a 1 hour IV infusion, every 3 weeks IN COMBINATION WITH DOCETAXEL: -RECOMMENDED DOSE: 1250 mg/m2 orally 2 times a day (morning and evening; equivalent to 2500 mg/m2 total daily dose) for 2 weeks followed by a 1 week rest period given as 3 week cycles Comments: -The manufacturer prescribing information for docetaxel should be consulted for premedication advice. -The tablets should be swallowed whole with water within 30 minutes after a meal. Use: Breast Cancer: -In combination with docetaxel for the treatment of patients with metastatic breast cancer after failure of prior anthracycline-containing chemotherapy -As monotherapy for the treatment of patients with metastatic breast cancer resistant to both paclitaxel and an anthracycline-containing chemotherapy regimen or resistant to paclitaxel and for whom further anthracycline therapy is not indicated (e.g., patients who have received cumulative doses of 400 mg/m2 of doxorubicin or doxorubicin equivalents); resistance is defined as progressive disease while on treatment, with or without an initial response, or relapse within 6 months of completing treatment with an anthracycline-containing adjuvant regimen

Detailed Capscare dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Capscare are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

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ATP concentrations in the muscles of masseter, triceps, and quadriceps were lower in samples obtained 120 minutes after death than that of samples obtained immediately after death. This test combines the sensitivity of enzyme-based assays and the specificity of monoclonal reagents and represents an important contribution to the diagnosis of Toxoplasma gondii infection. Association between weight fluctuation and fasting insulin concentration in Japanese men. Interestingly, our results also indicate that ADAM19 can function as a negative regulator of KL-1 shedding in both COS-7 cells and mouse embryonic fibroblasts, instead of acting directly on KL-1. CTLA-4 is accumulated in lysosomes and secreted to the T cell-APC contact site upon TCR stimulation. In the asexual blood stages of malarial infection, merozoites invade erythrocytes and replicate within a parasitophorous vacuole to form daughter cells that eventually exit (egress) by sequential rupture of the vacuole and erythrocyte membranes. On the hydrolytic behavior of tinidazole, metronidazole, and ornidazole. Tegumental ultrastructure of the juvenile and adult Himasthla alincia (Digenea: Echinostomatidae).

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The Bowman-Birk Inhibitor is one of several nontoxic compounds exhibiting both potent anticarcinogenic activity and minimal toxicity. miR-155 Regulated Inflammation Response by the SOCS1-STAT3-PDCD4 Axis in Atherogenesis. However, the percentage of females with eggs in the oviduct or brood sac decreased significantly in mysids treated with E2 at 62.5, 125, 250 and 500 microg/l. Here we report on the identification of nucleotide transport proteins (NTT) of two obligate endoparasites, Caedibacter caryophila and Holospora obtusa, both alpha-proteobacteria, which reside in the vegetative macronucleus of Paramecium caudatum. A detailed literature search was conducted on PubMed, EMBASE, Cochrane Library, and Google Scholar using the key words. ERGIC1 encodes a cycling membrane protein which has a possible role in transport between endoplasmic reticulum and Golgi. In part, this might be explained by the inequitable distribution of retail, attracted by lower rents to disadvantaged neighbourhoods.

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This region, when cloned into the compatible vector pEC6, was found to cause decrease of segregational stability of the pGA1 derivative pKG48. Item Ordering and Computerized Classification Tests With Cluster-Based Scoring: An Investigation of the Countdown Method. In social interactions, individuals who are slower at differentiating between facial expressions signalling direct and indirect threat might be at a serious disadvantage. During the course of an extralarval molt induced by JH in day-3 larvae both the transcripts were present but they were relatively less abundant than in the controls. Effect of substituting increasing levels of organic Zn for inorganic Zn on performance, hematological and serum biochemical constituents, antioxidant status and immune response in rat. The new SEP does not require widening of the needle-guiding orifice of the septum cap and analytes are desorbed at a faster rate from the thinner sleeve, which reduces the risk of carry-over. Overcoming electrostatic repulsions during amyloid assembly: Effect of pH and interaction with divalent metals using model peptides. Changes in TMAoxi activity do not correlate with TMAO levels, suggesting that the activity of this enzyme does not play a key role in regulating TMAO concentrations in smelt. The composition of maternal plasma and foetal urine after feeding and drinking in chronically catheterized ewes during the last two months of pregnancy. Very high cost treatment for a single individual--a case report.

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The rare variant hypothesis postulates that genetic susceptibility to colorectal neoplasia within the general population is due to a number of low frequency variants in a variety of different genes. Special formulae make it possible to predict signal variations and to increase, decrease or even reverse contrast, thus obtaining as many morphological or functional images of the different media in the body. Modulation of 5HT1A receptors in the hippocampus and the raphe area of rats treated with clonazepam. The results indicate that adding a methylene unit to a branch increases the overall size of the dendrimer but replacing a methylene unit with an oxygen atom decreases the size of the dendrimer. Analysis of multiple thromboxane metabolites in plasma and urine. In this work we report on the development of a novel technique for high-resolution diffusion-weighted (DW) MRI based upon 3D steady-state free precession (3D-SSFP). Multiple R2R3-MYB Transcription Factors Involved in the Regulation of Anthocyanin Accumulation in Peach Flower. Therefore, we aimed to explore their predictive abilities regarding stroke and thromboembolism (TE) risk in AF patients. Inhibition of the enzyme was not accompanied by changes of the electrophoretic mobility of thymocytes. Early egg contractions and patterned parasynchronous cleavage in a living insect egg.

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Neutralization of plasma TF with TF-Ab partially decreased FVIIa efficacy. Four species, Perates monops (Brennan et Jones, 1960), Parasecia manueli (Brennan et Jones, 1960), Beamerella acutascuta Brennan, 1958, and Blankaartia sinnamaryi (Floch et Fauran, 1956), are recorded for the first time in Cuba and on new host species. Tomato leaf curl New Delhi virus (ToLCNDV) is a whitefly-transmitted bipartite begomovirus (genus Begomovirus, family Geminiviridae) that causes damage to multiple cultivated plant species mainly belonging to the Solanaceae and Cucurbitaceae families. This study was aimed to preliminarily investigate the distribution of BSEP gene SNP rs2287622 in the Han patients with chronic HCV-infection (CHC) in Hunan, China. The evaluation of results has been performed according to Seddon classification (1975).

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- The talon cusp, or dens evaginatus of anterior teeth, is a relatively rare dental developmental anomaly characterized by the presence of an accessory cusp-like structure projecting from the cingulum area or cemento-enamel junction. Compliance of asthmatic families with a primary prevention programme of asthma and effectiveness of measures to reduce inhalant allergens--a randomized trial. The estimated toluene/benzene ratio is very high at most of the sites. Using recombinant SCAP purified in detergent, we show that cholesterol acts by binding with high affinity and specificity to the 767 amino acid octahelical membrane region of SCAP. Force model for laparoscopic graspers: implications for virtual simulator design.

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The uptake level of selenate by Cu2O is markedly lower than that observed for selenite species in the same conditions. The main clinical characteristics of the tubular breast are breast asymmetry, dense fibrous ring around the areola, hernia bulging of the areola, megaareola, and hypoplasia of quadrants of the breast. Evidence for macrophage participation at the effector level of tumor cell rejection. This pilot study was performed from March 2008 through February 2010 to demonstrate that pregnancy can be achieved in a uterine allograft in the sheep model with the guidance of assisted reproductive technology. We reviewed 239 consecutive vasectomies performed between september 1998 and september 1999. I conducted larval survival trials in which the phenolic glycosides salicortin and tremulacin were administered with and without inhibitors of the major detoxication enzymes. The Goldman-Hodgkin-Katz theory fails to account for the observations. The aim of this study was to investigate different elements of the healthy donor effect. PDT treatment was performed by an intravenous (i.v.) injection of benzoporphyrin derivative monoacid ring A (BPD-MA)-entrapped liposomes or the PCLs (0.25 mg/kg in terms of BPD-MA), followed by exposure to a laser light of 689 nm with 150 J/cm(2) of fluence 15 minutes post injection. From discard ban to exemption: How can gear technology help reduce catches of undersized Nephrops and hake in the Bay of Biscay trawling fleet?.

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Effects of hypoxia on contents of essential elements in pika and rat heart. The effects of release height on center of pressure and trunk muscle response following sudden release of stoop lifting tasks. Osteoinductive effects of glyceollins on adult mesenchymal stromal/stem cells from adipose tissue and bone marrow. Furthermore, pnt1 pollen is less viable than the wild type, and pnt1 embryos were delayed in morphogenesis and showed defects in shoot and root meristems. This study belongs to an interpretative approach to the development and use of information systems.

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Effects of stress on psychophysiological parameters of electricity distribution network controllers in Ukraine. Notably, knockdown of Puma impaired BafA1-induced HCC cell death, and overexpression of Puma enhanced BafA1-mediated HCC cell death, suggesting a role for Puma in BafA1-mediated cytotoxicity. Toll-like receptors recognize pathogen associated molecular patterns and are crucially implicated in the induction of IL-12 secretion by APC. Kinetic resolution of an advanced secondary alcohol was then accomplished by using a peptide-based asymmetric acyl transfer catalyst that was discovered from a parallel screen of catalyst candidates. A conceptual design is presented for a nanoengine governor based on the end interfacial effect of two rotary nanotubes. The participants were recruited through GPs in Norway, and the interviews were performed in 2014. The error-related negativity (ERN) is an event-related potential (ERP) peak occurring between 50 and 100 ms after the commission of a speeded motor response that the subject immediately realizes to be in error. The c-Zr3N4 films are significantly harder (approximately 36 GPa) than both the orthorhombic Zr3N4 (o-Zr3N4) and ZrN films (approximately 27 GPa).

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Focusing on the underlying factor and item scores, the girls scored significantly lower than boys on the Antisocial factor. Integration of Translational Research in the European Organization for Research and Treatment of Cancer Research (EORTC) Clinical Trial Cooperative Group Mechanisms. Proceedings of 2nd International ativan withdrawal dosage Symposium on Autografting for Chronic Myeloid Leukaemia. Another approach is the use of clinical risk factors to detect women at high risk. Cross-centre replication of suppressed burrowing behaviour as an ethologically relevant pain outcome measure in the rat: a prospective multicentre study. Eyewitness memory is vulnerable to information encountered prior to a lineup. Department of Ophthalmology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany.

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The wet-heat resistance of Bacillus weihenstephanensis KBAB4 spores produced in a two-step sporulation process depends on sporulation temperature but not on previous cell history. The ceramic inlays were luted with Single Bond and RelyX ARC cement. The results indicated that the psychoeducational program may be effective in reducing distress, anxiety, and depression and in improving the QOL in breast cancer survivors. Significant clearance from the brain, however, causes changes in distribution and underestimation of CBF values when a conventional microsphere model is applied to prolonged data acquisition. Findings reflect heightened efforts in the criminal justice system to combat CP crimes. Laboratory-reared cats were vaccinated against FHV-1, FCV, and FPV, using 1 of 3 commercial vaccines, or maintained as unvaccinated controls. MCM2 and Ki-67 expression in human lung adenocarcinoma: prognostic implications. Considering the longer duration of surgery and the higher costs of the U-Blade (RC) lag screw, our results do not justify its use.

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Quality assurance in preoperative autologous blood collection from the viewpoint of the transfusion medicine physician. Here, we present the first comprehensive study of oral health among a living population in transition from the bush to village life, the Hadza hunter-gatherers of Tanzania, to test the hypothesis that the shift from foraging to farming, or agricultural intensification, inevitably leads to increased periodontal disease, caries, and orthodontic disorders. Daily totals of net photosynthesis were consistently higher for leaves at increased humidity in C. We report the solution structure and dynamics of the complex of a dimeric lac repressor DNA binding domain with nonspecific DNA. When control and Bcl-x(L) cells of equivalent size and pyronin Y fluorescence were compared, the kinetics of cell cycle entry were similar, demonstrating that the ability of Bcl-x(L) and Bcl-2 cells to enhance G(0) arrest contributes significantly to cell cycle delay. An endoscopic probe was developed to guide an OCT laser beam onto human cadaver eye tissue samples to detect CCs.

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