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Catapres (Clonidine)

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Catapres is an alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines.

Other names for this medication:
Arkamin, Clodict, Clonidine, Jenloga

Similar Products:
Adalat, Aurogra, Cenforce, Symmetrel, Nuvigil, Mestinon

Also known as: Clonidine


Clonidine transdermal is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk for heart attacks. These problems may be less likely to occur if the blood pressure is controlled.

Clonidine belongs to the class of medicines called antihypertensives. It works in the brain to change some of the nerve impulses. As a result, the blood vessels relax and blood passes through them more easily, which lowers blood pressure. When the blood pressure is lowered, the amount of blood and oxygen going to the heart is increased.

This medicine will not cure your high blood pressure, but it does help control it. Therefore, you must continue to use it as directed if you expect to lower your blood pressure and keep it down. You might have to take high blood pressure medicine for the rest of your life.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain clonidine. It may not be specific to Catapres-TTS-1. Please read with care.

Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many patients feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

To use the skin patch:

Use this medicine exactly as directed by your doctor. It will work only if applied correctly. This medicine usually comes with patient instructions. Read them carefully before applying the patch. Wash your hands with soap and water before and after applying a patch. Do not touch your eyes until after you have washed your hands. Do not try to trim or cut the adhesive patch to adjust the dosage. Check with your doctor if you think the medicine is not working as it should. Gently wash the area of skin where you will apply the patch with soap and water. Rinse the skin completely and dry with a clean, dry tissue. Apply the patch right away after removing it from the pouch. Do not cut it into smaller pieces and do not touch the sticky surface of the patch. Apply the patch to a clean, dry, and intact skin area on your upper, outer arm or upper chest. Choose an area with little or no hair that is free of scars, cuts, or irritation. Avoid putting the patch on skin areas where it could be rubbed off by tight clothing. Press the patch firmly in place with your fingertips to make sure that the edges stick well. The patch should stay in place during showering, bathing, or swimming for a full 7 days. If the patch becomes loose, press the edges against the skin and cover the patch with one of the white adhesive covers that are included in the package. Apply a new patch if the first one becomes too loose or falls off. It is best to apply each patch to a different area of the skin to prevent skin irritation.

To help you remember to use your medicine, try to apply the patch at the same time and on the same day of the week.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For transdermal dosage form (patch): For high blood pressure: Adults—One patch applied once every 7 days. Your doctor may adjust your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include feeling cold, irritable, weak, drowsy, or light-headed, or having weak reflexes, pinpoint pupils, slow heartbeats, shallow breathing, or a seizure.


Store the patches at room temperature in a closed container, away from heat, moisture, and direct light.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

After removing a used patch, fold the patch in half with the sticky sides together. Make sure to dispose of it out of the reach of children and pets.

Detailed Catapres-TTS dosage information

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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A 3D QSAR pharmacophore model and quantum chemical structure--activity analysis of chloroquine(CQ)-resistance reversal. To date, about 20 cases of SETTLE have been reported in the English medical literature. An animal cap was recombined with a quartet of micromeres, or micromere-descendants cultured in isolation, to form a recombinant embryo. On the value of aceclidine in the treatment of chronic simple glaucoma as compared with pilocarpine. The model can contribute to temporal reasoning in computer systems for decision support, data mining, and process and outcomes analyses by providing structured temporal information. The results indicate that severity and outcome in bulimia nervosa should be determined by measuring both cognitive and behavioral aspects of the symptoms. Calves in groups of 6 ingested the milk faster than calves housed in pairs, which suggests that the competition for milk was greater than in pairs. On the first visit, manual reduction of the buccal plate was carried out under local anesthesia, with repositioning of the right central incisor and splinting to the neighboring teeth. Techniques for detecting and quantifying anaerobic transformations of benzene, toluene, ethylbenzene, and xylene (BTEX) are needed to assess the feasibility of using in situ bioremediation to treat BTEX-contaminated groundwater aquifers. To inform the development of a new primary health care nursing structure and evaluate the new role associated with this, it will be important to have data on current practice nurse roles.

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A cDNA clone encoding this novel neuropeptide was shown to encode a single copy of this peptide. The relationship between a Dietary Approaches to Stop Hypertension (DASH) diet and CKD in elderly Koreans is unclear. ACTH, cortisone and splenectomy in therapy of acquired hemolytic anemia. In some patients, the presence of a cilio-retinal artery may worsen diabetic maculopathy. Although dignity, particularly the dignity of older adults, is often discussed in the health care literature, its meaning is not always clear. Laparoscopy remains the gold standard for diagnosis and surgical removal at that time should be first line treatment. Intraarterial bolus infusion followed by rapid removal of anticancer agents with hemocarboperfusion under local hyperthermia in advanced hepatic cancer.

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Diet scores and cardio-metabolic risk factors among Guatemalan young adults. An exact solution to the two-dimensional scattering properties of an anisotropic elliptic cylinder for transverse electric polarization is presented. The differences in the best corrected visual acuity and pupil diameter between the two groups were not statistically significant. We have shown previously that inhalation of cowshed dust extract (CDE) resulted in decreased airway reactivity, eosinophilic inflammation and sensitization in a mouse model of allergic asthma. Spironolactone (initial dose, 200 mg/day) was administered orally to 139 Japanese patients (116 females and 23 males) with acne. Identification of an astacin matrix metalloprotease as target gene for Hydra foot activator peptides. Assessing the impact of complications on the costs of Type II diabetes.

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R-TPA may be used effectively in the treatment of fibrin clots secondary to endophthalmitis following cataract surgery. Using the HAPPY mapping method, an acellular adaptation of the radiation hybrid method, we mapped a few hundred markers on the human, chimpanzee, and gorilla genomes. Furthermore, the support of endothelial cell survival by NO may further play a central role for the pro-angiogenic effects of NO. Metal complexes of some of these Schiff bases with divalent transition ions such as Zn(II), Cu(II), Co(II) and Ni(II) have also been obtained. Noncontact backscatter-mode near-infrared time-resolved imaging system: Preliminary study for functional brain mapping. This could help pediatrician surgeons to explain to a couple about neonatal surgical repair and plastic reconstruction in the prenatal period. Ile105Val polymorphism in exon 5 of glutathione S-transferase (GSTP1) gene was examined in a group of patients with motor neuron disease (MND) and control sample. Antioxidant activities of flavidin in different in vitro model systems. One thousand seven hundred and thirty-nine male and female participants in the MRC National Survey of Health and Development, also known as the British 1946 birth cohort, distributed throughout England, Wales and Scotland. The patients received either NIPSV (24 patients) or CPAP (22 patients) through a face mask.

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Taken together, these results suggest that ASC-1 may function as an AR coregulator and have a role in testicular functions. There is a widespread belief that positive thinking is a key strategy to cope with cancer. There seems to be a morphologic continuum ranging from focal basal cell hyperplasia (BCH) to florid adenoid basal cell tumor (ABCT). Meclofenamic acid (30 microM, 20 min) or resveratrol (10 microM, 20 min) was given after exposure to H(2)O(2) . Staging of patients with HCC in a cirrhotic liver is deficient due to the restrictions of the current imaging modalities. 40 Patients were examined during developing brain death and in brain death. The functions essential for the bacterium to grow and survive in the periodontal pocket, such as coaggregation and acquisition of amino acids, were also strongly inhibited by the combined action of both inhibitors. Combined chlorpromazine-reserpine therapy of psychiatric disorders.

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In a prospective study, 10 patients with isolated anterior cruciate deficiency were examined before and after replacement of the anterior cruciate (6, 12, 24 weeks) in a standardized technique. Host cell invasion by the apicomplexans: the significance of microneme protein proteolysis. Data were analyzed for adults with arthritis age 45 years or older from the 2001 Behavioral Risk Factor Surveillance System, an ongoing, state-based, random-digit-dialed telephone survey of noninstitutionalized adults living in the United States. Genetic disorders influencing lung formation and function at birth. Refractometric method of quantitative determination of certain preparations and medicinal mixtures. Results add new insights in finding influential observations in the studied data set. To outline the indications for and our experience with postoperative adjuvant external-beam radiotherapy (EBRT) in patients with eyelid or conjunctival cancers. This would imply fewer reoperations for pseudarthrosis, but small cohort sizes are inadequate to monitor these events.

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Treatment with adefovir dipivoxil for up to 240 weeks was well tolerated and produced significant, increasing improvement in hepatic fibrosis, durable suppression of HBV replication, normalization of liver enzymes, will flagyl treat urinary tract infection and delayed development of resistance. Bone mineral density was measured using quantitative computed tomography. Structural and optical studies of CdS nanocomposites synthesized by various routes. Here, we characterize the IFN-independent innate cellular response to virus-derived stimuli in Vero cells, a monkey kidney epithelial cell line deficient for IFN production. The addition of DCE-MRI may be an option to improve the specificity and PPV of diagnosing TZ cancer with FST2-WI and DW-MRI. Site-specific, thiol-mediated conjugation of fluorescent probes to cysteine-modified diabodies targeting CD20 or HER2.

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We aimed to compare the rates of consanguineous marriages between first cousins among parents of MS patients and a healthy unrelated control group. The down-regulated expression of pro-inflammatory cytokines in mammary tissues and aggravated systemic oxidative stress at parturition suggest that sows are in a vulnerable status during periparturient period. Immune serum possessed factors which reduced bacterial adhesion to the hemocytes. A case study is presented from Quzhou County in the North China Plain, an area characterized by highly intensive farming. Season influences FSH concentration in ovariectomized Ile-de-France ewes. Localization of the histamine H(2) receptor, a target for antiulcer drugs, in gastric parietal cells.

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The T allele in the dominant model was associated with an elevated risk for high SBP. Penetrating craniocerebral injuries: observations in the Iraqi Iranian War. Treatment of concurrent gemcitabine and radiotherapy for pancreatic cancer was reported to have a higher rate of severe acute intestinal toxicity. subtilis partial diploids were constructed by transforming parental and arginine hydroxamate resistant (Ahr) mutants with pUL2100, a plasmid generated by inserting the 6 kbp fragment into the integration vector pJH101. Protein-kinase-C iso-enzymes support DNA synthesis and cell survival in colorectal-tumor cells. Medical charts of 38 patients with epithelial neoplasms of salivary glands were reviewed. The effect of Helicobacter pylori eradication therapy on gastric antral myoelectrical activity and gastric emptying in patients with non-ulcer dyspepsia. Men undergoing radical prostatectomy for early-stage prostate cancer do not accurately recall their pretreatment HRQOL when asked several months or years later.

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In four out of ten cases, the side-to-side ratios of A/C were changed in the basal/low-dose/standard-dose AVS as 6.62/2.46/0.63, 2.13/0.41/0.14, 1.88/2.38/2.40, and 1.96/2.27/1.90 respectively. These data suggest that the phloem transport of the L-derivative is governed by a stereospecific amino acid carrier system energized by the proton motive force. Use of a gestational carrier for a patient with recurrent adverse pregnancy outcomes from early onset severe pre-eclampsia. The results of this study revealed that the identified flavonoids of Anastasia Black may be only partially responsible for the modulation of the MDR of mouse lymphoma cells. A total of 17 kinds of helminths were found at the 2 sites, including 15 nematodes, 1 trematode, and 1 cestode. Topographical characterization and microstructural interface analysis of vacuum-plasma-sprayed titanium and hydroxyapatite coatings on carbon fibre-reinforced poly(etheretherketone). Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle. Under superatmospheric conditions, lactic vasotec dose acid bacteria and members of Enterobacteriaceae were inhibited. She underwent an anterior orbitotomy with surgical excision followed by close observation. The most frequent symptom represents shortness of breath caused by muscle weakness.

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