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Colcrys (Colchicine)
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Colcrys

Colcrys is used to prevent gout attacks (sudden, severe pain in one or more joints caused by abnormally high levels of a substance called uric acid in the blood) in adults. Colcrys is also used to relieve the pain of gout attacks when they occur.

Other names for this medication:
Colchicindon, Colchicine, Coljoy, Goutnil, Zycolchin

Similar Products:
Dilantin, Adalat, Cardura, Benicar, Allegra, Rocaltrol

Also known as: Colchicine

Description

{name} (colchicine) affects the way the body responds to uric acid crystals, which reduces swelling and pain.

Because colchicine was developed prior to federal regulations requiring FDA review of all marketed drug products, not all uses for colchicine have been approved by the FDA. As of 2009, {name} is the only brand of colchicine that has been approved by the FDA.

The {name} brand of colchicine is FDA-approved to treat gout in adults, and to treat a genetic condition called Familial Mediterranean Fever in adults and children who are at least 4 years old.

Generic forms of colchicine have been used to treat or prevent attacks of gout, or to treat symptoms of Behcets syndrome (such as swelling, redness, warmth, and pain).

{name} is not a cure for gouty arthritis or Behcets syndrome, and it will not prevent these diseases from progressing. {name} should not be used as a routine pain medication for other conditions.

Dosage

Take Colcrys exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Do not purchase colchicine on the Internet or from vendors outside of the United States. Using this medication improperly or without the advice of a doctor can result in serious side effects or death.

Colcrys can be taken with or without food.

To treat a gout attack, for best results take Colcrys at the first sign of the attack. The longer you wait to start taking the medication, the less effective it may be.

You may need to take a second lower dose of Colcrys 1 hour after the first dose if you still have gout pain. Follow your doctor's instructions.

Your dose will depend on the reason you are taking this medicine. Colchicine doses for gout and Mediterranean fever are different.

Do not stop using Colcrys unless your doctor tells you to, even if you feel fine.

Call your doctor if your symptoms do not improve, or if they get worse.

If you use this medicine long-term, you may need frequent medical tests.

Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

Detailed Colcrys dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of colchicine can be fatal.

Overdose symptoms may include diarrhea, nausea, vomiting, stomach pain, muscle weakness, little or no urinating, numbness or tingling, weak pulse, slow heart rate, weak or shallow breathing, or fainting.

Storage

Store at a room temperature between 4 and 30 degrees C (39 and 86 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Colcrys are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Colcrys if you are allergic to Generic Colcrys components. Be very careful with Generic Colcrys if you're pregnant or you plan to have a baby. Do not take it in case you are a nursing mother. Generic Colcrys can harm baby. Do not use Generic Colcrys if you have liver or kidney disease. Be careful with Generic Colcrys if you take conivaptan (Vaprisol); digoxin (Lanoxin, digitalis); imatinib (Gleevec); isoniazid (for treating tuberculosis); an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), or telithromycin (Ketek); cholesterol-lowering medicines such as atorvastatin (Lipitor), fenofibrate (Antara, Lipofen, TriCor), fluvastatin (Lescol), gemfibrozil (Lopid), lovastatin (Mevacor, Altoprev, Advicor), pravastatin (Pravachol), simvastatin (Zocor, Simcor, Vytorin), and others; an antidepressant such as nefazodone; antifungal medication such as itraconazole (Sporanox), ketoconazole (Nizoral), miconazole (Oravig), or voriconazole (Vfend); HIV or AIDS medication such as atazanavir (Reyataz), darunavir (Prezista), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Invirase), ritonavir (Kaletra, Norvir), tipranavir (Aptivus); heart or blood pressure medication such as amiodarone (Cordarone, Pacerone), diltiazem (Cartia, Cardizem), felodipine (Plendil), nicardipine (Cardene), nifedipine (Nifedical, Procardia), quinidine (Quin-G), reserpine, verapamil (Calan, Covera, Isoptin, Verelan), and others; medicines used to prevent organ transplant rejection, such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), or tacrolimus (Prograf). Be careful with Generic Colcrys if you suffer from or have a history of have liver or kidney disease, heart disease, a stomach ulcer, ulcerative colitis, Crohn's disease, intestinal bleeding, or any other severe gastrointestinal disorder. Avoid grapefruit and grapefruit juice. It can be dangerous to stop Generic Colcrys using suddenly.

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