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Compazine (Prochlorperazine)

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Compazine is a first-generation antipsychotic. FDA indications include schizophrenia, schizoaffective, and other conditions presenting with symptoms of psychosis, as well as nausea and vomiting (post-chemotherapy, post-radiation therapy, pre- and post-operative setting, and other conditions).

Other names for this medication:
Bukatel, Compro, Emidoxyn, Eminorm, Ingametil, Meditil, Neurocin, Neurograin, Neurolice, Neuromol, Neuronit, Novapar, Nuroflow, Nuropar, Prochlorperazine, Procomp, Psygrain, Stemetil, Swigrain, Vasograin, Vertipro, Vestil

Similar Products:
Glucotrol, Cardura, Reminyl, Caverta, Suprax

Also known as: Prochlorperazine


Generic Compazine is taken for controlling severe nausea and vomiting and treating schizophrenia. It is also used for the short-term (4 weeks) treatment of generalized nonpsychotic anxiety. It may also be used for other conditions. Generic Compazine is a phenothiazine. It works by blocking a certain chemical (dopamine) in the brain. Compazine is also known as Prochlorperazine, Compro, Stemetil, Stemzine. Generic name of Generic Compazine is Prochlorperazine. Brand name of Generic Compazine is Compazine.


This section provides information on the proper use of a number of products that contain prochlorperazine. It may not be specific to Compazine. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

Do not take rectal suppositories by mouth or use it in the vagina.

To use the suppository:

If the suppository is too soft to insert, chill it in the refrigerator for 20 to 30 minutes or run cold water over it before removing the wrapper. Remove the wrapper and moisten the suppository with cool water. Lie down on your side and use your finger to push the suppository well up into the rectum. Make sure to wash your hands with soap and water before and after using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For rectal dosage form (suppository): For severe nausea and vomiting: Adults—25 milligrams (mg) 2 times a day. Children—Use and dose must be determined by your doctor.


If you overdose Generic Compazine and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Compazine dosage information

Side effects

The most common side effects associated with Compazine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of prochlorperazine suppository in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

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The first study created and pilot-tested the scale, using data from 158 parents of children with 4 selected chronic conditions to calculate estimates of reliability and validity. Nerve growth factor and the immune system: old and new concepts in the cross-talk between immune and resident cells during pathophysiological conditions. The surfaces show the development of nano pattern and kinetic roughening. Lack of association between early childhood immunizations and beta-cell autoimmunity. Deletion studies of USF-1 suggest that amino acids 143-197 regulate DNA-binding activity in a phosphorylation-dependent manner. Abiding by properly operative techniques, the optimal results can be obtained. Use of Rib-Based Distraction in the Treatment of Early-Onset Scoliosis Associated With Neurofibromatosis Type 1 in the Young Child. In the lymph nodes, VEGF and VEGF-C showed distinct binding patterns in agreement with the differential location of their specific receptors. This article discusses the care of patients with CMN, who often require a multidisciplinary approach involving pediatricians, family physicians, internists, dermatologists, psychologists, plastic surgeons, neurologists, and radiologists.

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Injection therapy of natural interferon-alpha was performed against chronic active hepatitis with hepatitis C virus infection. The aim was to evaluate changes in QOL among metastatic breast cancer patients receiving treatment derived from trials. This paper reports a simple and efficient gas burette system that allows automated determination of evolved gas volume in real time using only temperature and pressure measurements. Epithelial neoplasms of salivary gland origin are relatively uncommon in children and adolescents. The integrated model has been applied to study the feasibility and cost of carbon capture and sequestration at both new and existing coal-burning power plants.

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Our results with this series of patients suggest that nitinol stents can be safely used in children as a temporizing measure until tracheal resection can be safely performed. Functional beta1- and beta2-adrenoceptors in the left and right atrium of pre-hypertensive rats. On the basis of the clinical characteristics of the depressive syndrome the patients were divided into two groups: the stressory hyperergic type (Group 1) and the torpid hypoergic type (Group 2). The micelles are taken up efficiently by the cells, which triggers disassembly, releasing the encapsulated material. As such, it adheres to most extracellular surfaces, rendering it more difficult to measure compared with other released cellular proteins.

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Drug disposition can be described by the traditional processes of absorption, distribution, metabolism, and elimination. The analysis reveals that nurses identify three aspects of the position-social relations, the acquisition of skills and knowledge, and work and control-as having both advantages and disadvantages over other work roles within nursing. Sec61beta, a subunit of the protein translocation channel, is required during Drosophila development. A major factor VIII binding domain resides within the amino-terminal 272 amino acid residues of von Willebrand factor. Mothers overwhelmingly found the addition of a second child to the family to be a positive experience regardless of the effort it took to accommodate their lives to the needs of two children. Neuroimaging in refractory partial seizures: comparison of PET, CT, and MRI. The difference in relative selectivities between the two inhibitors was confirmed using prostaglandin E2 (PGE2), which reversed responses to NA depressed by BW 755C to a greater extent than those depressed by NDGA.

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Polyonychia in congenital onychodysplasia of the index finger (Iso and Kikuchi syndrome): a report from India. It was also observed that drought-stress increased the length and density of trichomes dramatically especially in the susceptible genotypes, and that the length and density of trichomes were positively related to fungal biomass of F. To audit the quality of acute asthma care in two tertiary hospitals in a state in the southwestern region of Nigeria and to compare the clinical practice against the recommendations of the Global Initiative for Asthma (GINA) guideline. The approach is demonstrated by examining fragmentation patterns of insulin chain B (a 30-residue peptide), and ubiquitin (a protein containing 76 amino acids). SMCs replated on vitronectin after culture on monomer collagen result in PAI-1 accumulation at focal adhesions and colocalization with alpha(v)beta3 integrins. Urine and blood cultures positive for the same pathogen within 7 days were used to define catheter-associated bacteriuria and bacteremia.

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We sought to determine whether an imbalance between angiogenic and antiangiogenic factors exists in asthmatic airways. Arnebin-1 was applied topically daily on wounds of hydrocortisone-treated or untreated animals. Biochemical and biological properties of single-chain urokinase-type plasminogen activator. Most patients with poor overall appetite have good appetite for several specific foods. Recovery of laryngeal sensation after superior laryngeal nerve anastomosis.

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An audit improves the quality of water within the dental unit water lines of three separate facilities of a United Kingdom NHS Trust. Climate-Related Local Extinctions Are Already Widespread among Plant and Animal Species. Other buffer functions, including filtration of groundwater nitrate and stabilization of channel erosion sources of sediments, may be important in some regions. Trillium coating of cardiopulmonary bypass circuits improves biocompatibility. Genetic and environmental influences on the junior temperament and character inventory in a preadolescent twin sample. We demonstrate this effect using a new technological approach to create very straight and narrow injection bands in such arrays, and completely resolve bands of DNA of lengths 48,500 and 16,7000 base pairs. Amelioration of Gamma-hexachlorocyclohexane (Lindane) induced renal toxicity by Camellia sinensis in Wistar rats.

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We confirmed the characteristic circadian rhythm in JME with the tendency to go to bed later at night, to get up later in the morning, and to feel fit at a later time during the day compared to patients with TLE. With the novel-response procedure, participants are trained under a standard two-response (drug vs. Women were prescribed daily iron and folic acid supplements throughout pregnancy. Characterization of intracellular reverse transcription complexes of Moloney murine leukemia virus. Intensification of beef production will include more breeding of heifers at 15 months, and more problems with dystocia. Toll-like receptor 4 (TLR4) is a receptor for saturated fatty acids (SFAs), global deficiency of which has been shown to protect against inflammation, insulin resistance and atherosclerotic lesion formation. The aim of this study is to evaluate the effect of clean sweep technique on the need for repeated surgery compared to a problem focused approach. Additional evidence is needed before AS is implemented as part of routine clinical practice. Cell proliferation was increased in the ciliated epithelial cells of the oviduct in hens receiving 8mg MGA compared to those receiving 0mg.

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Deletion mapping of the transposon ends shows that fewer than 100 bp are sufficient for transposition of Tc3. Patients with limited response to these interventions may require further evaluation. To identify research traditions that have motivated and guided interruptions research, and to note research questions posed, gaps in approach, and possible avenues for future research. We will make further studies on circadian variation of autonomic nervous function. In conclusion, antimicrobial catheters have been shown to be highly cost effective in decreasing the risk of catheter-related bloodstream infection. A major variable related to the disease-specific quality of life was perceived stress, followed by the severity of asthma. The results show that 2,3-DPG enhanced or induced platelet aggregation in the presence of suboptimal concentrations of Na-Arachidonate. It is concluded that this test is interesting, especially for the chronic and sero-negative Brucellosis diagnosis.

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Hemoglobin level in pregnancy in women treated at the Gynecologic Consultation Center of the 4th Polyclinic of Sofia. During the development of the disease, ROS are generated by endogenous sources, notably the NADPH oxidase enzyme family and uncoupled nitric oxide synthase, due to a mutual reinforcement between ROS and humoral factors. The cytokine tumour necrosis factor-alpha (TNF- ambien in drug screen alpha) has been implicated in the aetiology of rheumatoid arthritis in humans as well as of experimental arthritis in rodents. Rare display of eight concentric halos in Tampere, Finland, on 5 June 2008. We investigated the role of ITA in embryonic chick sympathetic and dorsal root ganglionic neurons, which depend on nerve growth factor (NGF) for their survival. Different approaches to stationary phase development have been reported in contemporary CEC literature. The intraoperative bloodloss was markedly decreased in water-jet-cutting tonsillectomy. We studied the mRNA expression of apoptosis-related genes in peripheral blood mononuclear cells from chronic-phase CML patients before imatinib treatment. Japanese encephalitis virus (JEV) is an important cause of encephalitis among children in Cuddalore district, Tamil Nadu, India.

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Our findings suggest that the simultaneous administration of pemetrexed and paclitaxel is suboptimal. Transthoracic echocardiography revealed a left atrial myxoma impinging on the mitral valve. An all-oral regimen of etoposide and cyclophosphamide was developed for use in poor-prognosis extensive disease small-cell lung cancer. A series of morphologic and hemodynamic parameters were evaluated using computational fluid dynamics, based on patient-specific three-dimensional geometrical models. Thanks to increasing experience with endoscopic sinus surgery, excision and removal of noncomplex tumors of the anterior skull base have become possible. New antiepileptic drugs: basic science and clinical use in children and adults. avium complex were much more susceptible in broth than in agar for rifampin, ethambutol, and streptomycin.

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Leuconostoc mesenteroides is a member of lactic acid bacteria (LAB) with wide applications in the food and medical industries. Of particular interest is the question of how to link the molecular and cellular mechanisms of synaptic plasticity to learning operations at the systems level, which are expressed behaviourally as reinforcement-related learning. aureus released significantly less soluble CP5 in vitro and in vivo. Constructing Tissue Microarrays: Protocols and Methods Considering Potential Advantages and Disadvantages for Downstream Use. In the present study, we assessed the chronic influence of selected hypothalamic factors on the relative proportions of GH- and PRL-secreting cells in pituitary cultures derived from 5-day-old rats. For comparison, PBMCs derived from healthy adult volunteers were similarly stimulated with 2M3B1PP and the resulting gammadelta T-cells were analyzed for effector functions. Empathy, however, is difficult to define: it is not the same as kindness, as it implies a degree of psychological insight into what the patient is thinking or feeling. The critical role of residues 43R and 44Q of carcinoembryonic antigen cell adhesion molecules-1 in the protection from killing by human NK cells.

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Administration of 6-OHDA slightly decreased the incorporation of the proline into the non-collagen protein of the SHR posterior cerebral artery, but failed to reduce blood pressure in each rat strain. An updated process model for carbon oxidation, nitrification, and denitrification. The results were compared to those obtained by PSO and GA training in which the network architecture was kept fixed. Several figures of merit (performance indices) were identified which might be used is klonopin a bad drug for routine rating and specification of handpieces. Dynein coimmunoprecipitated with overexpressed pericentrin, suggesting that the motor was sequestered in the cytoplasm and was prevented from associating with its cellular targets. Anxiety behaviour of the male rat on the elevated plus maze: associated regional increase in c-fos mRNA expression and modulation by early maternal separation. Some of these issues would probably not be identified during routine health care. The need for a specific chain length or a specific number of double bonds, or for both, is more flexible. Generic inverse variance method was used to undertake Meta-analysis.

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Carbonic anhydrase catalyzes cyanamide hydration to urea: is it mimicking the physiological reaction?. Therapeutic hypothermia was initiated and maintained for 24 hours. New evidence for an enduring wound-healing concept: moisture control. Immunofluorescent analyses with N-terminal 14 amino acids antiserum revealed that HB9 was strongly expressed in epidermal basal cells of the outer scale face in tarsometatarsal scale skin. We present our experience with latissimus dorsi (LD) flap based VLNT for lymphedema treatment.

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There was probably an adaptive benefit in those individuals in which late-produced cells were capable of passing through the layers of already migrated cells, thus making contacts with superficial afferents and generating corticocortical and local circuits that processed the information before producing an output. Here we locate the intramolecular SH3-binding site at the region of amino acid residues 286-340, where Ser-303, Ser-304, and Ser-328 that are among several serines known to become phosphorylated upon cell stimulation exist. Preoperative characteristics may influence morbidity and mortality in patients undergoing coronary artery bypass grafting (CABG). Further clinical and mechanistic studies of lamotrigine use in mania are warranted. Remitting seronegative symmetrical synovitis with pitting oedema (RS3PE) syndrome mainly affects elderly men and responds well to steroids. Current dummy limbs show qualitatively correct kinematics under air bag loading, but they lack biofidelity in long bone bending and fracture. Neoplasia in inflammatory bowel disease: surveillance and management strategies.

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There was also a transient dose-related increase in plasma TxB2 but no change in plasma 6-keto PGF1 alpha levels. This report briefly summarizes the deliberations of conference working groups (composed primarily of State and Federal public health officials) that addressed these issues. The effect of levothyroxine on the proliferative activity of the thyroid follicular cells. The technique described in this study may be useful to identify earlier starting points for follow-up and physiotherapy. This suggests that genes and/or gene classes associated with plant defenses against abiotic and biotic stress may be co-regulated. Data on demographics, disease conditions, and unhealthy lifestyle behaviors were gathered. A sutureless technique for an oozing type of postinfarction LV free wall rupture is effective. Growing evidence suggests that beta-amyloid (Abeta) peptides play a central role in mediating vascular endothelium dysfunction, but the extent to which immune mechanisms are involved in this process remains unclear. Next, whether oltipraz inhibits TGFbeta1-mediated Smads activation or Smad-mediated PAI-1 induction was determined in L929 fibroblasts.

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The infarct area of the left ventricle was significantly larger in irradiated mice than healthy controls 14 days after infarction, although it was similar between the groups at the baseline. Manifesto on small airway involvement and management in asthma and chronic obstructive pulmonary disease: an Interasma (Global Asthma Association - GAA) and World Allergy Organization (WAO) document endorsed by Allergic Rhinitis and its Impact on Asthma (ARIA) and Global Allergy and Asthma European Network (GA2LEN). A reverse genetics approach for recovery of recombinant influenza B viruses entirely from cDNA. Solvent-assisted nucleophilic cleavage of the intermediate beta-silyl cation is proposed to play a role in the solvent-dependent chemoselectivity. Oocytes that fail to fertilize by 24 hours after ICSI can resume apparently normal fertilization and early embryonic development in response to electrical stimulation. Gradually it evolved into prominent, well-demarcated areas of peeling skin in moist and traumatized zebeta dose regions. Celiac disease presenting with vertebral fracture in an elderly man. Correlations between lactate and ventilatory thresholds and the maximal lactate steady state in elite cyclists. Bomb threats and searches: time to reassess procedures and retrain employees. Both groups were roughly accurate in predicting the behavior of their peers.

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This may have significance in understanding the pathogenetic mechanisms of liver injury in this infection. Three different approaches were applied: P1: whole blood diluted by an isotonic saline solution before activation, P2: undiluted whole blood with the single and P3: with the twofold concentration of the stimulating agent. The conservation of these responses suggests that MCs play a crucial role in recruitment biaxin type of antibiotic of various CCR-expressing cells into the tissue in a manner dependent on immunoglobin E, and that FcepsilonRI-mediated induction of several CC chemokines and 4-1BB is highly conserved between human and mouse. We find that current policy has favored the growth of particular types of plans. The cell killing occurred with autologous and allogenic tumor cells from patients with primary and possibly recurrent tumors. The model investigated is also applicable to ECG-gated cardiac imaging for the detection of stenosis. TNF-alpha and TNFRII gene polymorphisms does not play an important role in susceptibility to CWP of Han race. Vaginal implantation of urinary tract urothelial carcinoma is a rare finding, with few cases reported in the literature. We illustrate the method by tracking human motions using sparse visual-shape data (3-D surface points and normals) gathered from imperfect silhouettes. Patient 2: A 41-year old male presented in our department with a divided pigmented nevus on his left eye involving the upper and lower lid laterally.

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