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Flagyl (Metronidazole)
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Flagyl

Flagyl is in a class of drugs called nitroimidazole antimicrobials. It works by stopping the growth of bacteria. This medicine will only help infections caused by bacteria and will not work for the common cold, flu, or other viral infections.

Other names for this medication:
Aldezole, Amotein, Anabact, Aristogyl, Collazole, Dirozyl, Dumozol, Efloran, Entizol, Etron, Flagicure, Flanizol, Florazole, Giardyl, Imizine, Metral, Metrazol, Metrocream, Metronid, Metronidazole, Metrosa, Metrovax, Metrozin, Metrozine, Metsina, Micogyl, Negazole, Nidazea, Onida, Patryl, Riazole, Robaz, Rosalox, Supplin, Tismazol, Triconex, Trikozol, Unigyl, Vandazole, Varizil, Zobacide, Zyomet

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Also known as: Metronidazole

Description

Metronidazole is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Flagyl. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine is to be used only in the vagina. Use it at bedtime, unless your doctor tells you otherwise.

Do not get it into your eyes, nose, mouth, or skin. If this medicine does get into your eyes, wash them out right away with large amounts of cool tap water. If your eyes still burn or are painful, check with your doctor.

This medicine comes with a patient information leaflet and patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Wash your hands with soap and water before and after using this medicine.

Nuvessa™ is available inside a prefilled applicator. The applicator is open at one end where you will insert the plunger and has a pink cap on the other end where the medicine will come out.

Vandazole® is in a tube. You will use an applicator to put the gel into your vagina. The applicator has a plastic tube called a barrel that is open at one end and has a plunger (another piece of plastic that can move inside the barrel) at the other end.

To use the medicine:

To fill the applicator: For cream or gel dosage forms: Nuvessa™: With the pink cap still on, push the tip of the plunger into the open end of the prefilled applicator. Pull the cap off before you insert the applicator into your vagina. Vandazole®: Break the metal seal at the opening of the tube by using the point on the top of the cap. Screw the applicator onto the tube. Squeeze the medicine into the applicator slowly until it is full. Remove the applicator from the tube. Replace the cap on the tube. For vaginal tablet dosage form: Place the vaginal tablet into the applicator. Wet the vaginal tablet with water for a few seconds. To insert vaginal metronidazole using the applicator: For all dosage forms: Relax while lying on your back with your knees bent (or in any position that you feel comfortable). Hold the full applicator in one hand. Insert it slowly into the vagina. Stop before it becomes uncomfortable. Slowly press the plunger until it stops. Withdraw the applicator. The medicine will be left behind in the vagina. Remove the applicator from your vagina. Use each applicator only once, and then throw it away.

To help clear up your infection completely, it is very important that you keep using this medicine for the full time of treatment, even if your symptoms begin to clear up after a few days. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses. Also, continue using this medicine even if your menstrual period starts during the time of treatment.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For bacterial vaginal infections: For vaginal dosage form (cream): Adults—One applicatorful (500 milligrams [mg]), inserted into the vagina. Use the medicine 1 or 2 times a day for 10 or 20 days. Children—Use and dose must be determined by your doctor. For vaginal dosage form (gel): Nuvessa™: Adults and children 12 years of age and older—One applicatorful (5 grams [g]) inserted into the vagina once (at bedtime). Each applicatorful of Nuvessa™ contains 65 mg of metronidazole. Children younger than 12 years of age—Use and dose must be determined by your doctor. Vandazole®: Adults—One applicatorful (5 grams [g]) inserted into the vagina once a day (at bedtime) for 5 days. Each applicatorful of Vandazole® contains 37.5 mg of metronidazole. Children—Use and dose must be determined by your doctor. For vaginal dosage form (tablets): Adults—One 500 milligram (mg) tablet, inserted high into the vagina. Use the medicine once a day in the evening for 10 or 20 days. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Generic Flagyl and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Flagyl overdosage: dizziness, seizures, torpor, retching, nausea, lack of balance, problems with coordination, tingling.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Flagyl ER dosage information

Side effects

The most common side effects associated with Flagyl are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of metronidazole vaginal gel in the elderly.

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Outcomes evaluation: continuing education in rheumatology for nurses. The worst values were observed prior to transplantation, with a significant improvement at 3 months. To clarify the mechanism of interaction between nortriptyline and terbinafine. The mixture is easy to handle and can be moulded into different shapes in room temperature. Mice induced by prior irradiation (550 rad) to heal infection did not develop indomethacin-reversible depression in responsiveness to Con A. At the upper margin of the imaginary reconstructed auricle, the mean diameters of the artery and vein were 1.7 mm and 2.2 mm, respectively.

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This assembly may recapitulate a step in the historical development of tRNA synthetases. Less time (5 hr) is needed for LPS to exert its inhibitory effect on an anti-sheep red blood cell response than on Il-2 synthesis (at least 24 hr). There is overwhelming evidence that the infection is a major cause of distal gastric adenocarcinoma. Differential regulation of the two metallothionein genes in common carp. Counseling to reduce intake of dietary fat, cholesterol, and sodium was based on Cardiovascular Dietary Education System (CARDES) materials, which included food-picture cards, a nutrition guide (self-help and full-instruction group), a video and audiotape series, and 4 classes (full-instruction group only). Patients with International Classification of Diseases, ninth revision, clinical modification, procedure codes for lung resection were included in the sample. The responsible mediators are often bacterially derived cell wall molecules, such as lipopolysaccharide or lipoteichoic acids, which typically stimulate monocytes and macrophages to release a wide variety of inflammatory cytokines and chemokines. This is achieved by introducing alkyl substituents onto the spacers of readily prepared bis(pyridylimine) ligands. VIA6E8 (IgG1) and VIIB2E11C9 (IgM) did not cross-react with ovine prolactin (oPRL), ovine leutinizing hormone (oLH) and porcine follicle stimulating hormone.

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The samples treated with the hydrofluoric acid solution presented higher alkaline phosphatase activity. 2002) and the Wayne State University Human Thoracic Model (WSUHTM, Wang 1995 and Shah et al. This paper reports an investigation into the experiences of Registered Nurses caring for hospitalized Pakistani patients in the United Kingdom. In some subjects the 2.5 micrograms dose elicited GH secretion as compared with placebo. After saline infusion, dopamine hydrochloride was infused in three consecutive doses (5, 10, and 15 microg x kg(-1) x min(-1)). The accuracy of EUS in the local staging of gastric lymphoma has to be improved if nonsurgical treatment strategies based on the grade of malignancy and stage of the disease are to be used.

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Ethanol exposure decreases cell proliferation and increases apoptosis in rat testes. In epithelia obtained from the tonsillar mucosa removed during surgery, cell viability was evaluated by trypan blue staining. The behavioural response of Triatoma pseudomaculata to chemical substances present in their faeces or cuticle (footprints) was analyzed. Here we show that such models can be derived from an integrated-scale analysis generated from three different types of functional relationship: Wells-Riley mathematical model, competing-risks model, and Von Foerster equation, both of the key epidemiological determinants involved and of the functional connections between them. The VAI is a valid measure of vasculitis activity that correlates highly with the PGA. However, the physiological explanation for the high-low phenotype is unknown.

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Ischemic preconditioning has been shown to protect the liver from ischemia/reperfusion injury. The fibroblast cells adhered to the RGD43 scaffold and extended long filopodia. This study was undertaken to compare the effects of carbon dioxide, helium, and nitrous oxide gas on tumor spread in an animal model to determine whether the type of gas used for the pneumoperitoneum would affect tumor spread. Recent advances in the understanding of ALI/ARDS and mechanical ventilation have revealed that lung-protective ventilation strategies may attenuate ventilator-associated lung injury and improve patient morbidity/mortality. Some limits to evidence-based medicine: a case study from elective orthopaedics. The lymph nodes were ovoid or round, homogeneous, well-defined and ranged from 9 to 10 mm in diameter.

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Lateral hypothalamic control of metabolic factors related to feeding. The influence of the platelet count on the incidence of thrombotic and haemorrhagic complications in polycythaemia vera. At the cellular level, Notch/Kras coactivation promotes rapid reprogramming of acinar cells to a duct-like phenotype, providing an explanation for how a characteristically ductal tumor can arise from nonductal acinar cells. Ultrastructure of ovine ruminal epithelium and localization of sodium in the tissue. Biochemical and immunological characterization of a glycosylated alpha-fucosidase from the zyrtec 10 mg bid invertebrate Unio: interaction of the enzyme with its in vivo binding partners.

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The relationship of the wavelet approach to current hypothesis-testing methods is shown with an example and discussed. Nonadherence with antiretroviral therapy can be established on the basis of persistently elevated HIV RNA levels that decrease with DOT. To report the outcomes of cataract surgery in children with retinopathy of prematurity (ROP). The stimulatory effect of fibroblasts showed a biphasic character: keratinocyte proliferation increased in the initial phase but decreased in later stages of cell culture. We demonstrate that following surgical resection, HSV1716 is safe when injected into the brain adjacent does differin gel help cystic acne to excised tumour. This is in part due to the roles of ETS transcription factors in basic biological processes such as growth, proliferation, and differentiation, and also because of their regulatory functions that have physiological relevance in tumorigenesis, immunity, and basal cellular homoeostasis.

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Bradyrhizobium japonicum is one of the soil bacteria that form nodules on soybean roots. Changes in eulexin 250 mg regional cerebral blood flow in the thalamus after electroconvulsive therapy for patients with complex regional pain syndrome type 1 (preliminary case series). The efficacy of intervention by specialized nutrition support teams in infection control related to these catheters has been demonstrated. New evidence for spatially correlated TC-LC mechanisms in thermoluminescence of LiF:Mg,Ti. As expected, IR rats exhibited significantly lower startle amplitude and PPI than their SR counterparts. Case 1: a 5-year-old girl with monosomy X presented with acute respiratory failure. We observed that the thymic output, distribution of T-cell subsets, thymidine incorporation, number of T-cell divisions, and y-interferon production were comparable to those of age-matched control. A single investigator also scored a physician global assessment (PGA) of disease severity on a 10-point scale.

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Analyses conducted using a hIGF-1 specific ELISA kit showed all transgenic plants produced hIGF- vasotec dose 1 and the accumulated hIGF-1 increased from the E. The limited data on the effects of dialysis dose on acute renal failure suggest that the relationship between acute renal failure comorbid conditions and death in critically ill patients is more complicated than generally recognized. We researched the subclasses of IgA (IgA1 and IgA2) by the direct immunofluorescence (IF) staining method using specimens in which we identified the deposition of IgA through zero-hour renal transplant biopsies from donors without urinary abnormalities. Combinations of monoclonal antibodies defining the OKT 4 positive lymphocyte subset in the peripheral blood of intravenous drug abusers suggest that the 4B4 positive helper inducer population is greatly reduced in subjects infected with HTLV III. Northern blot and biochemical analyses show no compensatory up-regulation of matrilin 2 or 3 in the cartilage of knockout mice.

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Histological examination revealed that the artificial peritoneum consisted of a flat mesothelial monolayer upon a stromal matrix. Infection, Oxidative Stress, and Changes in Circulating Regulatory T Cells of Heart Failure Patients Supported by Continuous-Flow Ventricular Assist Devices. Sensory systems in amphioxus: a window on the ancestral chordate condition. The dimerization of the Si atoms in the single atom row based on a (1x3) Si substrate model plays a critical role in stabilization of the surface structure and in determining the electronic properties. Epsin binds to the EH domain of POB1 and regulates receptor-mediated endocytosis. We have established and characterized primary mouse and rat cell strains for studies designed to complement in vivo gene mutation assays using the Big Blue(R) mouse or rat. Occlusion at the right coronary ostial anastomosis in a 36-year-old woman with aortitis syndrome who underwent a composite graft with a Dacron coronary graft bactrim dosing toxo is described. In patients who have undergone two or more previous attempts at repair the outcome is less favorable. Clinical and pathological studies of tuberculosis among the aged. Electron therapy for orbital and periorbital lesions using customized lead eye shields.

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Results indicated a good performance of the Hill model, although the neural network predictions appeared to be superior. The high concentration mostly induced inhibitions which increased or decreased as a consequence of the repeated application of the chemicals. Chlamydia pneumoniae infection and its role in asthma and chronic obstructive pulmonary disease. Bactericidal and bacteriolytic activities of carumonam and its effect on bacterial morphology. Oxaliplatin has become one of the major cytotoxic agents for the treatment of gastrointestinal tumors. The caffeine metabolic ratio as an index of xanthine oxidase activity in clinically active and silent celiac patients. This extracellular location of ApbE is required for its function, since a cytoplasmic form (ApbE(cyto)) did not allow an apbE mutant to grow in the absence of thiamine. The mode of inhibitory action of human CGRP seemed to be similar to that of calcitonin and the relative potency of human CGRP to inhibit bone resorption is one five-hundredth of that of human calcitonin. Our goal was to identify fractions strongly recognized by donors and differences among the donor groups of possible relevance for vaccine development.

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The procedure requires 2 donors that will donate one lobe each that will replace the recipient lungs. Determination of intracellular polyamine concentrations, demonstrated decreased putrescine and spermidine levels after DFMO administration. This case demonstrates the need to consider alternate pathogens when treating preseptal cellulitis, change medications accordingly, and consider alternate treatments as needed. The proteins of nuclear matrix preparations from Physarum polycephalum were compared with analogous mammalian fractions by gel electrophoresis, DNA-binding studies and immunological tests. Western blot analysis was used to confirm protein expression of PD-L1. Re-basing 1991 statistics on the current set of boundaries allows real demographic change over the period since 1991 to be measured. A new antibody immobilization strategy based on electro-deposition of gold nanoparticles and Prussian Blue for label-free amperometric immunosensor. The distal part was placed intraperitoneally and anchored in deeper soft-tissue layers using a fibre mesh cuff.

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Community pharmacies are potential providers of email medication counseling services. Outcomes were satisfactory according to both patients and gynecologists. the MND and HD groups had the greatest needs for support and appeared most receptive to a palliative approach. The loss of YPT1 function, studied in cells with the YPT1 gene on chromosome VI regulated by the galactose-inducible GAL10 promoter, led to arrested cells that were multibudded and exhibited a complete disorganization of microtubules and an apparent loss of nuclear integrity. The aim was to evaluate the clinical effectiveness, pharmacodynamics and pharmacokinetics of a range of Tincture of Opium (TOP) doses in the management of opioid withdrawal. Weaknesses in generativity emerged as stronger potential endophenotypes in this study, suggesting that this aspect of EF should play a central role in cognitive theories of autism. Isolation of a tryptophan--requiring mutant of Ophiostoma multiannulatum. The beta-glucanase gene from Bacillus amyloliquefaciens shows extensive homology with that of Bacillus subtilis. Attempting to affect recognition in synthetic systems by copying the detailed chemistries to which nature has been led over millenia of evolution does not seem practical for most applications.

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The formation and functioning of the factor X activating complex on the surface of cultured human venous endothelial cells (HVEC) were investigated. The results support the hypothesis that the Talk Test approximates ventilatory threshold on both treadmill and cycle. Bioactivity of bacteria was maintained during the immobilization process. To investigate involvement of the nervous system in ipsilateral and contralateral joint inflammation. Providing direct performance feedback may be a useful tool for integration into graduate medical education programs.

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