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Levothroid (Levothyroxine)
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Levothroid

Levothroid is a synthetically prepared thyroid hormone that can improve symptoms of thyroid deficiency such as slow speech, lack of energy, weight gain, hair loss, dry skin, and feeling cold. There are several brand and generic Levothroid choices available, though they may not be interchangeable.

Other names for this medication:
Eltroxin, Levothyroxine, Levoxyl, Roxin, Synox, Synthroid, Thyronorm, Thyrosec, Thyrowin, Thyrox, Unithroid

Similar Products:
Ventolin, Imitrex, Rogaine, Inderal, Cialis

Also known as: Levothyroxine

Description

Levothyroxine injection is used to treat myxedema coma (severe hypothyroidism), a condition where the thyroid gland does not produce enough thyroid hormone. The powder form of levothyroxine injection can be used as a substitute for the oral dose when a rapid effect is needed and when the oral route is not allowed.

This medicine is to be given only by or under the supervision of your doctor.

This product is available in the following dosage forms:

  • Powder for Solution

Dosage

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection form (powder for solution):
    • For the treatment of hypothyroidism:
      • Adults—50 to 100 micrograms (mcg) injected into a muscle or vein once a day. People with very serious conditions caused by too little thyroid hormone may need higher doses.
      • Children—Dose is based on body weight and must be determined by your doctor.
  • For injection form (powder for solution):
    • For myxedema coma:
      • Adults—The loading dose is usually 300 to 500 micrograms (mcg) injected into a vein once a day. The maintenance dose is usually 50 to 100 mcg injected into a vein once a day. Your doctor may adjust your dose as needed and tolerated.
      • Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Generic Levothroid and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Use the oral liquid within 15 days after opening the pouch. Keep the ampules in the pouch until you are ready to use them.

Side effects

The most common side effects associated with Levothroid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of levothyroxine in children.

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This technique was applied to a lysine-accumulating strain, 15901.7, and to its low lysine pool derivatives, ply-1, ply-4 and ply-9, which were selected for their low polyphosphate pools. The vaccinia virus C12L protein inhibits mouse IL-18 and promotes virus virulence in the murine intranasal model. Four commercially available PHH3 antibodies were tested on 9 grade 3 invasive breast cancers processed in the same batch. Post diploma programs should acknowledge and build on the skills and abilities nurses bring to the educational setting, yet challenge learners to develop critical self appraisal. It was proved that the fibrous dysplastic tissue is deficient in bone sialoprotein. The patient presented a periapical radiolucent area associated to a root from the maxillary left primary second molar. The number of movement bursts per hour, burst duration, onset-onset interval between successive bursts (OOI) and the percentage incidence were analysed in detail. Perioperative management of glucose 6 phosphate dehydrogenase deficiency.

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A phylogenetic analysis of the functionally characterized NF-Y genes revealed that, across plant species, NF-Y proteins functioning in the same biological process tend to belong to common phylogenetic groups. Inhibitory effect of two newer antidepressants, Lu 5-003 and Lu 3-010, on serotonin uptake in human blood platelets in vitro. Aging and shiftwork: the effects of 20 years of rotating 12-hour shifts among petroleum refinery operators. In this review, we describe a survey of recently reported druggability prediction methods mainly based on networks, statistical pocket druggability predictions and virtual screening. Neovascularization was quantitated by digital image analysis in corneal flat preparations. Dynamic adjustments of walking behavior dependent on noxious input in experimental low back pain.

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Statins are inhibitors of 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase used for the therapeutic reduction of cholesterol-containing plasma lipoproteins. Multilevel binary logistic regression models were constructed to determine the association between these patterns of comorbidity and smoking status, smoking cessation advice, and smoking cessation medication (nicotine replacement therapy) prescribed. Long-term anticonvulsant therapy and vitamin D metabolism in ambulatory pubertal children. The published Hugoniot data of low-Z diatomic molecules have a universal behavior. Relativistic effective core potentials were used for the I, Xe, and B atoms. MRA, conventional pulmonary angiograms, and pulmonary perfusion scintigrams were performed. The aim of the current study is to clarify the possibility of molecular target therapy with Ki23057 for treating scirrhous gastric cancer. Wage-price restraints would affect the economy--but in what way?. fumigatus filtrates induced a specific decrease in transepithelial resistance, hyperpolarization of the epithelium, and cytoplasmic vacuolization of HNEC compared with both A.

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Overexpression of ZmWRKY4 in protoplasts upregulated the expression and the activities of antioxidant enzymes, whereas ABA induced increases in the expression and the activities of antioxidant enzymes were blocked by the RNAi silencing of ZmWRKY4. Gasification temperature was found to be the most influential factor. In translation deformities, the realignment of the mechanical axis requires a parallel restaggering made by a translation-osteotomy or by a counterangulated double osteotomy. Limitations of titanium dioxide and aluminum oxide as ossicular replacement materials: an evaluation of the effects of porosity on ceramic prostheses. Emotional distress and psychiatric syndromes are prevalent in the breast cancer population at large. Pregnancy outcomes and clinical data were subsequently obtained. Radical surgery for cancer of the cervix metastasized to peripheral lymph nodes (excluding exenterations).

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This region is considered a unimodal visual area with little direct involvement of other sensory modalities. Using this method, as many as four viable cell types have been simultaneously analyzed in a single sample. They were given rituximab, a monoclonal anti-CD20 antibody, achieving a response with minimal side effects. We show here for the first time that alcohol inhibits lipopolysaccharide (LPS)-induced NFkappaB activation in human monocytes by decreasing DNA binding of the p65/p50 heterodimer as seen in electrophoretic mobility shift and supershift assays. Whole-body scanning and dorsal spine SPECT revealed no focal increased uptake. Shooting ranges may constitute an import site of elevated exposure to lead.

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Antenatal corticosteroid administration to premature, growth restricted fetuses may not be beneficial and even have adverse effects on neonatal outcome. Nicotine is one of many substances that may be acquired through active and passive smoking of tobacco. The economic evaluation was conducted from a societal perspective. Bioavailability of organic phosphorus in a submerged aquatic vegetation-dominated treatment wetland. Implications of isoform multiplicity of microphthalmia-associated transcription factor in the pathogenesis of auditory-pigmentary syndromes.

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On plastid symbiosis in Tontonia appendiculariformis (Ciliophora, Oligotrichina). In this chapter, we describe single-molecule fluorescence resonance energy transfer (FRET) assays to observe the target binding and reaction pathways of miRISC composed of a recombinant Argonaute and a small RNA. Two different forms, sporadic and familial, have been described for MEN2. IPL skin rejuvenation using relatively shorter wavelengths and pulse widths brought about significant macroscopic and quantitative improvements, especially in the treatment of epidermal pigmentation and improvement of basic skin tone. The production of mycotoxins and other metabolites by 109 strains of Fusarium langsethiae, Fusarium poae, Fusarium sporotrichioides, and F. He did not have bacterial meningitis 19 months after the operation. Moreover, he attempts to criticize evolutionary theories of aging by showing that explanations other than evolutionary theories of aging probably account for the variation in human lifespan across countries. Immunological studies were also carried out on the patients and the results were reported.

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Cox modeling demonstrated significantly improved survival in patients diagnosed in the latter cohorts. Therefore, a field study was carried out measuring exposure to antifouling paints. Biotransformation of mycotoxins in animals comprises phase I and phase II metabolisation reactions. Investigating the CVD Synthesis of Graphene on Ge(100): toward Layer-by-Layer Growth. The three purified UDP-glucuronosyltransferases are separate and distinct proteins, with different amino acid compositions and peptide maps generated by limited proteolysis with Staphylococcus aureus V8 proteinase.

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This is the first report describing granulocytic differentiation activity of a falcarindiol derived polyacetylenic compound on leukemia cells. Bone marrow examination revealed sideroblasts, a low M:E ratio and evidence of enhanced intramedullary destruction of erythroid cells. This review explores cancer survivorship from an international perspective in two ways: from a cancer control perspective through a review of cancer control strategies and from a cancer care perspective through a review of clinical practice guidelines and research on cancer follow-up care. The salivary ferning test and measurement of beta-glucuronidase levels are not good methods for home ovulation testing. Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) has been reported to induce apoptosis in various tumour cell lines and, recently, also in normal cells. Children of epileptic women on medication with Primidon are of lower weight and have smaller is it ok to take cold medicine with zyrtec heads than children from epileptic mothers without medication and children from parents without epilepsy. Sarcopenia in older mice is characterized by a decreased anabolic response to a protein meal. Multiple doses of 50 mg amisulpride once daily were devoid of any detrimental effects on EEG and psychomotor performance and cognitive function after total sleep deprivation.

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Retinoic acid and arsenic trioxide target the protein stability and transcriptional repression activity of the glucotrol dosing fusion oncoprotein PML-RARA, resulting in regression of acute promyelocytic leukemia (APL). The present study demonstrates the scope of the N-chlorosuccinimide (NCS)/organophosphine reagent system that forms multiple sp(3)C-Cl bonds in a regularly repeating pattern with proper stereochemical configurations and evaluates its applicability to various epoxides having elaborate structures. As such, it may prove useful in situations where rapid response to therapy is critical or other medical therapies are inadequate. Control of the liver reticuloendothelial system through the central nervous system. Human resistance to decompression sickness and nonspecific methods of its elevation. An increased biological efficiency of carbon ions could be confirmed in radioresistant tumour cells with respect to the induction of reproductive cell death and of unstable as well as stable chromosome aberrations. The abutment screws of the 2-piece temporary healing abutments were tightened to 20 N-cm at the insertion appointment and did not need to be tightened again during the course of orthodontic therapy. Spinal Cord Injury-Assessing Tolerability and Use of Combined Rehabilitation and NeuroAiD (SATURN Study): Protocol of An Exploratory Study In Assessing the Safety and Efficacy of NeuroAiD Amongst People Who Sustain Severe Spinal Cord Injury. Physical fitness was determined on a bicycle ergometer and body composition was determined using bioelectrical impedance analysis.

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Effective refractory periods (ERPs) were determined at baseline and after application of propafenone (2 mg/kg), dofetilide (30 microg/kg), or chromanol 293b (10 mg/kg) by the extrastimulus technique (BCL 300 and 850 ms). A laboratory-scale study was undertaken to evaluate the liquid state bioconversion (LSB) in terms of biodegradation of microbially treated domestic wastewater sludge (biosolids) as well as its kinetics. There is strong evidence that the processes used by rehabilitation services are effective at reducing mortality and morbidity, yet purchasers still feel that there is insufficient evidence to warrant buying rehabilitation. Presuming how much coreg to overdose that legs play an important role in assessing the oviposition substrate, we assessed the sensitivity of their taste receptors. Also, the classification of the initial severity of clubfoot is essential to evaluate the outcome of the treatment. In vivo beta-defensin gene expression in rat gingival epithelium in response to Actinobacillus actinomycetemcomitans infection. This article reviews recent advances in psoriatic arthritis (PsA) over the past several years with emphasis on early diagnosis, better understanding of pathogenesis, and new therapeutic approaches. Analysis of progenitor cell involvement in B-CLL by simultaneous immunophenotypic and genotypic analysis at the single cell level. The uniformed outward distribution of the cardiac electric field suggests that it is not dipolar but a sphere-like single source when the interference of different potentials of the reference points over the body surface is excluded. Anal carcinoma of the elderly treated with radiotherapy alone or with concomitant radio-chemotherapy.

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We exploit span space extraction techniques to retrieve operations necessary to update isosurface geometry from neighboring time steps. Hemoptysis of bronchial origin occurring in patients with arrested tuberculosis. Interestingly, we found that in the gacA mutant strain, the EIIANtr protein was present in its unphosphorylated state. An urgent UK investigation was launched to assess risk of invasive Mycobacterium chimaera infection in cardiothoracic surgery and a possible association with cardiopulmonary bypass heater-cooler units following alerts in Switzerland and The Netherlands. These diseases can cause a variety of myopathic syndromes and can become clinically manifest at any age.

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We have employed multi-fold sensitive sequence search methods to provide a repertoire of 252 putative interleukin-8 proteins and homologues, which are shared across humans, aves and fish. The discrepancies between two close rural populations indicates the need for an individual approach when designing programs of tobacco control. The expression, subcellular localization, and importance of Bax for resveratrol-provoked apoptosis were assessed in human HCT116 colon carcinoma cells and derivatives with both bax alleles inactivated. Agonist binding to the labeled receptor is associated with variations in the fluorescence properties of 5-hydroxytryptophan due to specific agonist-induced conformational changes. Climate is a major driving force behind malaria transmission and climate data are often used to account for the spatial, seasonal and interannual variation in malaria transmission. pylori 26695 genome sequence revealed the presence of a putative protein with homology to Esherichia coli outer membrane phospholipase A (PldA). Menatetrenone (MK-4) inhibits bone resorption and enhances osteoblast-induced mineralization. Chemical communication is also shown to be important in the life style of the solitarious phase. comparison and illustrations of the difference between bubble formation by cavitation (vaporization) and degassing (liberation of CO(2)).

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Surgical samples, tumor biopsies, and lymphocytes from these patients were collected for biological studies. The expression of sialoglycoconjugates during the dimethylsulfoxide (DMSO)-induced differentiation of Herpetomonas samuelpessoai was analyzed by flow cytometry and Western blotting using sialic acid-specific lectins. The degradation processes that occurred in drugs under investigation are described with kinetic parameters (k, t0.1, and t0.5) and energy of activation (Ea). In current guidelines, only surveillance colonoscopy is recommended after endoscopic resection of polyps with high-grade dysplasia, whereas intensive, multimodality surveillance using colonoscopy, radiological imaging and tumor marker measurements is recommended following surgical resection of invasive colorectal cancer. Protective effect of D-glucose, L-leucine and fetal calf serum against oxidative stress in neonatal pancreatic islets. Guidelines for allogeneic transfusion emphasize minimizing use to avoid transmission of serious illness.

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