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Lipitor (Atorvastatin)
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Lipitor

Lipitor is an inexpensive drug that lowers levels of cholesterol and triglycerides in the blood. Lipitor may also reduce the risk of heart attack or stroke in patients with risk factors for heart disease. This drug is more popular than comparable drugs. As of 2011, it is available in generic and brand versions.

Other names for this medication:
Ampliar, Atocor, Atoris, Atorlip, Atorvastatin, Atorvastatina, Atovin, Biger, Cardyl, Cardyn, Colostat, Danelip, Larus, Lipicon, Lipidan, Lipidra, Lipinor, Lipitin, Lipium, Lipivastin, Lipobi, Liponorm, Lipovastatin, Liprimar, Livas, Lorvaten, Tahor, Tarden, Tarimyl, Tiginor, Torivas, Torvacard, Trova, Vasolip, Zarator, Zoamco

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Also known as: Atorvastatin

Description

{name} (atorvastatin) belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins."

{name} is used together with diet to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).

{name} is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors such as genetically high cholesterol.

{name} is for use in adults and children who are at least 10 years old.

Dosage

Take Lipitor exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Lipitor is usually taken once a day, with or without food. Take the medicine at the same time each day.

Do not break an Lipitor tablet before taking it, unless your doctor has told you to.

You may need to stop using this medicine for a short time if you have:

uncontrolled seizures; an electrolyte imbalance (such as high or low potassium levels in your blood); severely low blood pressure; a severe infection or illness; or surgery or a medical emergency.

It may take up to 2 weeks before your cholesterol levels improve, and you may need frequent blood test. Even if you have no symptoms, tests can help your doctor determine if Lipitor is effective.

Lipitor is only part of a complete treatment program that may also include diet, exercise, and weight control. Follow your doctor's instructions very closely.

Store at room temperature away from moisture, heat, and light.

Detailed Lipitor dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 20 to 25 degrees C (68 to 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Lipitor are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Lipitor if you are allergic to atorvastatin, or if you have:

liver disease; or if you are pregnant or breastfeeding.

Atorvastatin can harm an unborn baby or cause birth defects. Do not use if you are pregnant. Stop taking Lipitor and tell your doctor right away if you become pregnant. Use effective birth control to prevent pregnancy while you are taking this medicine.

Atorvastatin may pass into breast milk and could harm a nursing baby. Do not breastfeed while you are taking Lipitor.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

liver problems; muscle pain or weakness; kidney disease; diabetes; a thyroid disorder; or if you drink more than 2 alcoholic beverages daily.

Lipitor can cause the breakdown of muscle tissue, which can lead to kidney failure. This happens more often in women, in older adults, or people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

Atorvastatin is not approved for use by anyone younger than 10 years old.

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The grafted surfaces are hydrophilic below 32 degrees C and hydrophobic above this temperature. The short-term stability of a restored tooth is mainly affected by the presence of defects which act as stress raiser, while the long-term stability of a restored tooth is mainly affected by the seal of the restorative material on the dental structures. Statewide health maintenance organization in Minnesota, USA, 1995. Electron-microscopically, the cisternae of the r-ER and Golgi apparatus were prominently dilated in these neurons. Furthermore, proaminopeptidase I accumulates in mon1Delta cells in a proteinase-protected form. We describe the clinical course and present the various histological findings followed by a review of the literature. While the stoichimetric reaction of the Ru(vinylsilane)(CO)(3) complex with an alkyne led to the formation of the corresponding cyclopentenone (PKR product) at 100 degrees C, the ruthenacyclopentene intermediate was quantitatively produced at 50 degrees C. The results of conventional testing for hip instability were compared with ultrasound screening in 1001 neonates. Here I review the current status of in vitro systems for NHEJ, summarize the results obtained and information gained, and discuss the outlook for biochemical approaches to study NHEJ.

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A unique localization of mechanoreceptors in the periodontal tissue of guinea pig teeth. Ribosomal RNA genes are used for microbial species detection and identification in natural environments, and current assessments of microbial diversity are based on these sequences. Our results indicate no transmission barrier for sheep BSE prions to infect BoPrP-Tg110 mice, but the course of the disease is accelerated compared to the effects of the original BSE isolate. Partial catheter occlusion was defined as a spontaneous flow less than 60 drops/min. Therefore, joint force and pressure inferences from external kinematic and kinetic data, without corroborating direct, internal measurements, should be made with more caution than is evident in the current literature. This event does not appear to have an immediate Antarctic counterpart, suggesting that the climate see-saw between the hemispheres (which dominated the last glacial period) was not operating at this time. Chorismate mutase isoenzymes from Sorghum bicolor: immunological characterization. Pacific steelhead (Oncorhynchus mykiss) exposed to chlorpyrifos: benchmark concentration estimates for acetylcholinesterase inhibition. The distribution of activating antibody in chromatographic fractions of ribonuclease antisera and their competition with inhibiting antibody for enzyme sites.

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In brain and tumor cells, the hexokinase isoforms, HK-I and HK-II, bind to the voltage-dependent anion channel (VDAC) in the outer mitochondrial membrane. The findings suggest that the proposed SIS could be used to perform audiological screening tests and to recommend appropriate hearing-aid gain values to the hearing-impaired subjects. For the common and rare groups of soil arthropods, there were some differences in four forests. The new GaN phases have typical porous structures, constructed by alternating tetragons and hexagons around the original tube walls. Heat denaturation may provide a simple method for distinguishing Ids determined by conformational antigen from primary structure-dependent Ids.

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Random assignment to placebo or coenzyme Q10 at dosages of 300, 600, or 1200 mg/d. The findings of this study suggest that the HPA-5b allele is a genetic risk factor for the development of OVC in patients with SCA. Dysosteosclerosis: a case with unique dental findings and SEM evaluation of a hypoplastic tooth. Effect of chronic heart failure on nuclear factor kappa B in peripheral leukocytes. Development of review criteria for assessing the quality of management of stable angina, adult asthma, and non-insulin dependent diabetes mellitus in general practice.

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Northern blot analysis revealed that induction of USAG-1 mRNA was restricted to the Day 5 pregnant or pseudopregnant uterus. Despite these encouraging results, none of these findings have achieved genome-wide levels of statistical significance, and none have been consistently replicated. High injection pressures during intraneural injection may be indicative of intrafascicular injection and may predict the development of neurologic injury. Inbred mice expressing endogenous mouse mammary tumor virus envelope proteins can be infected with exogenous virus, and the mammary tumors that develop in these mice usually have many proviruses integrated in their genomes, indicating that this virus is not subject to receptor interference. Community Health Workers perceptions in relation to speech and language disorders. Northern blot analysis of specific A beta and A alpha mRNA levels in these various lines indicated that more class II mRNA, and presumably more A beta and A alpha chains, were required to achieve expression of Abm12 beta Ab alpha equal to that of Ab beta Ab alpha, suggesting that the previously noted reduction of Ia expression on cells from bm12 mice reflects a decreased ability of Abm12 beta Ab alpha chains to pair, or to reach the membrane. Further investigation is warranted to define the optimal treatment dose and schedule. Patients with systemic autoimmune and/or inflammatory diseases have an increased risk of infections, particularly pneumoccocal invasive infections.

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Three polymerase chain reaction (PCR) techniques were compared to analyse the genetic diversity of Clinacanthus nutans eight populations in the northern region of Peninsular Malaysia. This gives milnacipran certain pharmacokinetic advantages, such as low inter-individual variation in plasma levels, low potential for drug interactions, and limited impact on hepatic cytochrome P450 systems. Factors affecting the escape of Francisella tularensis from the phagolysosome. Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface. The human cytochrome P450 sub-family: transcriptional regulation, inter-individual variation and interaction networks.

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Autism is a severe developmental brain disorder that appears in infancy, persists throughout life, and is characterized by impaired social interaction, abnormalities in communication (both verbal and nonverbal) and restricted interests. The chromosome-based challenge assay using fluorescence in situ hybridization: a possible test for increased cancer susceptibility. The article suggests that faintness evolved in response to middle paleolithic intra-group and inter-group violence (of con-specifics) rather than as a pan-mammalian defense response, as is presently assumed. Treatment with ethinyl estradiol reduced total cholesterol and apolipoprotein A-I concentrations in the serum of female and male animals. Effect of intravenous ascorbic acid medication on serum levels of soluble transferrin receptor in hemodialysis patients. The current notion is that mucosal enteroendocrine cells act as primary chemoreceptors by releasing signaling molecules in response to changes in the luminal environment, which in turn activate nerve terminals. Extracellular zinc stimulates ERK-dependent activation of p21(Cip/WAF1) and inhibits proliferation of colorectal cancer cells. The result may provide a potential mechanism for 5GG in cancer chemopreventive action. Inhibitory antitumor cell activity of IMC-18F1 was assessed in cell-based kinase and growth assays.

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Induced currents of 5-13 mA were measured for the medical devices. Curarizing alkaloids of various species of the Brazilian Strychnos: alkaloids of Strychnos trinervis. Injected isobutene was oxidized to isobutene oxide, which indicated that a toluene ortho-monooxygenase enzyme system was likely responsible for the observed c-DCE and t-DCE transformations. Severe atopic dermatitis (AD) often cannot be adequately controlled with topical agents. We then show an initial application to the study of pathway evolution.

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We used a CD61 mAb as a model for the HPA-1a alloantibodies and confirmed the results with purified IgG fractions from HPA-1a alloimmunized women. CTGF orchestrates the actions of important local factors evoking cardiac fibrosis. We determined the MICs of ethambutol for both Mycobacterium avium and Mycobacterium tuberculosis strains by using broth dilution (7H12 broth, radiometric method) and agar dilution (7H11 agar) methods. Moreover, in PCOS group, betatrophin levels were significantly negatively correlated with waist hip ratio (WHR), fasting insulin level (FINS) and HOMA-IR, whereas, significantly positively correlated with adiponectin level. A total of 45 patients underwent curative total gastrectomy and esophagojejunostomy with jejunal pouch construction (27 patients) or ReY (18 patients), using the EEA. Highly potent p21(WAF1)-derived peptide inhibitors of CDK-mediated pRb phosphorylation: delineation and structural insight into their interactions with cyclin A.

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News clippings offer intriguing injury prevention possibilities. Lung matrix incorporation of plasma fibronectin reduces vascular permeability in postsurgical bacteremia. The aim of this study was to develop endoscopic methods for suturing to variable predetermined depths in the wall of the GI is zantac tablets cause cancer tract and to allow fixation of adjacent hollow organs under EUS control. TSHus was performed at admission in all patients and completed by a full laboratory work-up in case of abnormal results. Synchronization and phase-resetting by glutamate of an immortalized SCN cell line. Foot kinematics are not recreated following tarsal coalition resection, despite the favorable clinical outcome observed. Prostate specific antigen bounce phenomenon after external beam radiation for clinically localized prostate cancer.

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Available data suggests that NO donors can be a useful tool in the process of induction of labour causing the cervix to be more favourable in comparison to placebo. Clinical, biochemical and histological features of patients with ANA/SMA and/or anti-SLA autoantibodies were compared in a secondary analysis of data acquired prospectively. This study also investigates the role of combined neo and adjuvant locoregional immunochemotherapy in patients considered initially as non-amenable to resection. Western blot analysis of ten neuroblastomas confirmed the lack of Fas expression and the presence of strong FasL expression in all samples and pro-caspase 3 expression in five tumours, of which four belonged to the favourable type. Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157. Although varied findings have been reported, no consistent abnormal findings in sweat glands have been established by histological study or electronmicroscopic study. Antiserotonin agents inhibited the hypoalgesia and part of the edema. Cotransfer of the Ed alpha and Ad beta genes into L cells results in the surface expression of a functional mixed-isotype Ia molecule.

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It is postulated that they will replace topical corticosteroids as first-line treatment of eczema. ER-alpha activation was specifically associated with arsenic-induced lung adenocarcinoma and adenoma but not with nitrosamine-induced lung tumors. STUDY SETTING AND DESIGN: Field based cross sectional survey covering urban non-slum, slum and peri-urban areas of a large metropolitan city. A clinical decision support system for prediction of pregnancy outcome in pregnant women with systemic lupus erythematosus. Raman spectroscopy indicates growth of sp(2)-hybridised, ordered regions in size and/or number within the amorphous carbon-hydrogen network as a result of the Ca-O-incorporation. Hydroquinone, an excellent reducing substrate, protected against hydroperoxide-induced inactivation when present in less than 3-fold molar excess over hydroperoxide. Renal artery embolism: thromboaspiration and catheter directed thrombolysis - A successful case.

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Production and evaluation of hydroxyapatite reinforced polysulfone for tissue replacement. The place of the centre of the force in central occlusion is determined. The article reports on a system of care for psychiatrically ill children and adolescents that has been designed, established and expanded since 1980 by a university department in a rural region. Moreover, treatment with DMAI was not observed to affect the interaction between the Toll-like receptor 4, MyD88, and TRAF6 as well as mitogen-activated protein kinase activation. A 10 dB(A) elevation in LDEN and LNIGHT was associated with GCS. In recent years, several studies have been published on these polymorphisms in pneumococcal and meningococcal disease ambien dosage males , many with apparently conflicting results.

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Recently, increases in the temporal and spatial scale of conformational sampling and comparison sulfasalazine drug nutrient interactions of the more diverse conformational ensembles thus generated have revealed the importance of sampling rare events. These chronic bacterial infections are risk factors for acute cardiovascular events, but they may also have some role in the etiopathogenesis of atherosclerotic process itself. This minimized the risk of major complications related to unstable anterior chambers such as uveal effusion and posterior capsular tear. Differential value of comparison with previous examinations in diagnostic versus screening mammography. Rats primed with eCG at 21 or 23 days of age showed abnormally ruptured corpora lutea in which the cumulus-oocyte complex (COC) was trapped or had been released to the ovarian interstitum, invading the ovarian stroma and blood and lymphatic vessels.

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Accelerated wound healing in mice with a disruption of the thrombospondin 2 gene. Obstructive sleep apnea (OSA) is a sleep disorder that disproportionately affects African Americans (hereafter referred to as blacks). Development of Semliki forest virus in mouse brain: an electron microscopic study. The dosemeters were placed in regions corresponding to parotid and submandibular glands, mandibular bone, thyroid gland, skin, eye lenses and brain. It was concluded that glutathione reductase (GR) deficiency is the only acquired enzyme deficiency in our group of PV patients and that radiation and chemotherapy did not induce further reduction in the activities of any of the enzymes tested. The aim of this study was to determine whether simultaneously prolonged CIT and WIT was associated with early graft outcome after clinical OLT. Apatite-forming ability of glass-ceramic apatite-wollastonite - polyethylene composites: effect of filler content. The adult population of New Zealand in the periods 1980-81 and 1992-93. Extragonadal germ cell tumors are uncommon, and although they morphologically resemble their gonadal counterparts, unexpected gonadal presentation increases the potential for erroneous diagnoses. After adsorption of hydrogen on the more reactive sites in the beginning of the adsorption experiments a regular pattern, which is different for room and elevated temperature, is observed for the less reactive sites.

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The highest mobility was found in the healthy test subjects, the lowest in patients with a plain impingement. Real-time redox measurements during endoplasmic reticulum stress reveal interlinked protein folding functions. Acute methylphenidate treatment has reduced hippocampal DARPP-32 protein levels in old rats, glucotrol xl generic name while chronic methylphenidate treatment has decreased them in old rat hippocampus and young rat cerebellum. An experimental model of tibial counterface polyethylene wear in mobile bearing knees: the influence of design and kinematics. Seroprevalence of malaria in inhabitants of the urban zone of Antananarivo, Madagascar. This locus, designated fru, contains a beta-fructosidase gene (fruA), a gene encoding a hydrophobic protein that is closely related to non-PTS sugar permeases of the proton symport type (fruP), and a gene coding for a transcriptional regulator of the LacI/GalR family (fruR). caninum serostatus alone should not be used to determine whether cows should be culled. viscida extract significantly reduced ethanol-induced gastric ulceration in mice. These factors were not elevated by SAH alone or in a separate cohort of patients with ischemic stroke, suggesting that these factors might play a role in the pathogenesis of human cerebral vasospasm. Role of histone acetylation and DNA methylation in the maintenance of the imprinted expression of the H19 and Igf2 genes.

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Histidine-rich glycoprotein binds to DNA and Fc gamma RI and potentiates the ingestion of apoptotic cells by macrophages. Therefore, this study suggest that intervention strategies targeting vitamin D deficiency rickets should give emphasis to children with protein-energy malnutrition, since it is strongly and independently associated with vitamin D deficiency rickets. These findings corroborate the profiling of CNS effects to demonstrate pharmacological selectivity, and further support SPV as biomarker for anxiolysis involving GABA-ergic neurons. We present a new reconstruction algorithm for accurately characterizing chirped pulses, even if the pulse extends beyond the linear region of the phase modulation. Irradiation ensures the hygienic quality of food and extends shelf-life.

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To examine whether FLT-1, a VEGF receptor, interacts with heparin and which domain of FLT-1 binds to heparin, various extracellular domains of FLT-1 were expressed in a baculovirus/insect cell system: sFLT-1(1-7), sFLT-1(1-4), sFLT-1(1-3), and sFLT-1(1-2) containing immunoglobulin (Ig)-like loop one to seven, one to four, one to three, and one to two, respectively. Ocular cryptococcosis in Australia, with a report of two further cases. The differences show that non-Markovian effects are much more important for the steady-state 2D photon echoes than for the equilibrium populations. Finally, it offers some discussion and some conclusions related to the evidence and the incentives of UK pharmaceutical firms under the PPRS constraint. Seven modalities of comorbidity for coronary heart disease (myocardial infarction) and depression/anxiety are discussed. Modification of primary and recurrent genital herpes in guinea pigs by passive immunization. Data are from the National Survey of American Life, a national household probability sample of 5181 black respondents aged 18 years and older, conducted between February 2001 and June 2003, using a slightly modified adaptation of the World Health Organization World Mental Health version of the Composite International Diagnostic Interview. Patients with locally advanced pancreatic cancer who received gemcitabine chemotherapy or 5-FU-based CCRT showed better survival than those who received supportive care only. These cases support the hypothesis that colloid cysts are congenital lesions and provide some evidence of a possible genetic predisposition to their formation.

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A scheduled operation to prevent recurrence of pneumothorax has to be performed under relative indication in consideration of both the medical factor and the social factor of the patient. The capacity of B cells from such mice to utilize IL 2 as a growth factor has not been previously reported and is examined herein. Multiple studies have shown that these adhesion molecules are required for the normal recruitment of leukocytes during an inflammatory reaction. We describe in this report, the effects of this amino acid change on RAD51D protein interaction and function. Despite progressive symptoms and radiographic degeneration in the joints of the ankle and midfoot, fifty-four patients (95 percent) were satisfied with the result of the operation. In the sections stained by hematoxylin and eosin, the numerical density of RM profiles/mm(2) of periodontal ligament, the area of each RM profile and the number of epithelial cell nuclei profile/RM were obtained. Is generally accepted that active treatment should be instituted only in symptomatic patients and watchful waiting in asymptomatic ones. We have identified a founder mutation consisting of a single base-pair deletion in C2orf37 in eight families of Saudi origin. While the population is relatively small, just over 20.7 million, it is genetically diverse and is spread over a large land mass.

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We also discuss the potential future uses of colchicine in renal medicine and challenges faced with its use in patients with impaired kidney function. Knowledge of normal neurobiological development provides a powerful foundation for understanding the contributions that neurodevelopmental processes make to the etiology and sequelae of psychopathology across the life course. Information processing during face recognition: the effects of familiarity, inversion, and morphing on scanning fixations. Tree growth may be limited by a short growing season and further diminished, by shoot can a child take cough medicine and motrin and root damage reducing carbon and nutrient stores as well as by reducing carbon and nutrient uptake capacities. The effects of SAMe were studied in an additional 16 awake rats. The animals were sacrificed after 6 weeks, and the mechanical characteristics of the healing osteotomies were evaluated.

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The lack of effective treatments is correlated with the poor understanding of keloid pathogenesis. Racial-Ethnic Disparities in Uptake of New Hepatitis C Drugs in Medicare. This study examined whether maternal smoking during pregnancy is associated with MS in offspring. This is a previously unrecognized complication of heart transplantation with potential clinical implications, as coronary to extracardiac artery collaterals have been shown to cause myocardial ischemia. The present study was designed to elucidate the mechanisms of motoneuron death induced by serum deprivation and the potential neuroprotective effects of vascular endothelial growth factor (VEGF) in dissociated and organotypic rat spinal cord cultures.

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