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Manzolam (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Manzolam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Manzolam is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alcicalm, Alpanol, Alprac, Alpram, Alpramax, Alprasert, Alprocalm, Altok, Alzac, Alzocum, Alzokam, Ambulax, Anilam, Benzolam, Calmef, Dazolam, Deproz, Destres, Isorest, Mcalm, Mediprex, Optizole, Parazolam, Pecalm, Procalm, Restyl, Richpram, Selamb, Serxanti, Silam, Sinozol, Somaspas, Visram, Welnorm, Xycalm, Zamitol, Zocam, Zodia, Zolam, Zolar, Zolent, Zoltweet, Zopax, Zotam, Zotin

Similar Products:
Eulexin, Furadantin, Omnicef, Lopid, Clarinex, Starlix, Casodex, Tricor

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Take this medication by mouth as directed by your doctor. Dosage is based on your medical condition, age, and response to treatment. Your dose may be gradually increased until the drug starts working well. Follow your doctor's instructions closely to reduce the risk of side effects.This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as seizures) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Report any withdrawal reactions immediately.Along with its benefits, this medication may rarely cause abnormal drug-seeking behavior (addiction). This risk may be increased if you have abused alcohol or drugs in the past. Take this medication exactly as prescribed to lessen the risk of addiction.When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.Tell your doctor if your condition persists or worsens.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Manzolam XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Manzolam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alprazolam in the elderly. However, elderly patients are more likely to have unwanted effects (eg, severe drowsiness, dizziness, confusion, clumsiness, or unsteadiness) and kidney, liver, or lung problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

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Attempts to eradicate colonizing organisms of low virulence may result in their replacement by more problematic organisms, so over-vigorous use of antibiotics to try to prevent infections is not always wise. Participants were fit bilaterally and tested in 2 environments, an anechoic chamber and a moderately reverberant classroom, with the microphones in the fixed (cardioid) setting and the adaptive setting. Retrospective study of incidence of urethral stricture in Scotland. Microencapsulation of tumor necrosis factor oligomers: a new approach to proinflammatory cytokine inhibition. Growing evidence suggests that transcriptional effectors of the Hippo pathway, YAP and TAZ, promote resistance to various anti-cancer therapies, including cytotoxic chemotherapy, molecular targeted therapy, and radiation therapy. A prospective cohort study on the seroprevalence of rubella IgG antibodies was conducted at three large eye hospitals in Coimbatore, Madurai and Tirunelveli, Tamil Nadu, India, where young children with eye abnormalities attributable to congenital rubella are treated. Disruption of sanG abolished nikkomycin biosynthesis, reduced sporulation and led to brown pigment accumulation.

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Transjugular intrahepatic portosystemic stent shunt as a rescue treatment after sclerotherapy failure in variceal bleeding. Real-time sperm separation system: a review of Wang tubes and related technologies. Carbon nanotubes (CNTs) are being successfully implemented in drug delivery, sensing, water purification, composite materials, and bone scaffolds. To investigate the inhibitory effect of combination of antisense human telomerase RNA (anti-hTR) and antisense human telomerase catalytic subunit (anti-hTERT) on proliferation of cervical cancer Hela cell line cultured in vitro. Farnesyltransferase inhibitors were initially developed as Ras inhibitors as they inhibit the prenylation necessary for Ras activation.

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In any case of renal dysfunction in a rheumatic patient, the differential diagnosis should include renal disease independent from the rheumatic condition, infection, and drug-induced renal toxicity. The production of chemotactic cytokines in an allogeneic response. The low scrotal approach to the ectopic or ascended testicle: prevalence of a patent processus vaginalis. Initial studies looking at a possible role of bacterial manipulation of the immune system in IBD, looked at identifying a specific bacterial species, and were not representative of a feasible model of inflammation in IBD overall. The method showed the required features of specificity and sensitivity to detect aminoethylcysteine ketimine decarboxylated dimer in human plasma and in cultured cells after in vitro supplementation. A comparative study of thyroid axis functioning in chronic bronchitis patients with deficiency of kidney yang or kidney yin. Demonstration and study of physico-chemical characteristics of a placental protein binding cyclic AMPC. Swing and stance limb acceleration ground reaction forces and EMG amplitude were modulated according to initiation velocity.

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The relation between umbilical cord characteristics (cord length and coiling) and the success of external cephalic version. Even before voluntary locomotion, both legs acted in a cooperative manner, with the dynamic status of one limb affecting the timespace behavior of the opposite limb. Similar assessments of non-responders did not yield any specific predictors. Cell injury progressing to either necrosis or apoptosis by shared pathways can be leukeran 2mg tablets more aptly termed necrapoptosis. This paper aims to describe and analyze the prolonged efforts - spanning close to two decades - of developing and using electronic patient records in the large, university-based hospitals in Norway.

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Presynaptic receptors for virtually all transmitters have been identified throughout the nervous system. This data suggests that Hao2 should be examined as a candidate gene for the rat chromosome 2 (RNO2) BP QTL. Fifteen adult guinea pigs were randomly divided into 3 groups: sham-operated group (healthy controls) and 2 experimental groups wherein these guinea pigs were subjected to common bile duct ligation to induce acute cholecystitis. The low rates of total hip arthroplasty in the non-white groups was related to the much lower incidence of THR for primary coxarthrosis among non-whites than among whites. However, neurobiological mechanisms involved in this sensitization are largely omeprazole 40 mg vs prilosec otc unknown. We discuss in detail the mechanism by which the chaos is generated. Laminopathies are now recognized as a group of disorders due to mutations of the LMNA gene, which encodes A-type lamins. Although some practices were easier to implement than others, communication, education, and leadership were critical to the process. The Second World War saw a significant expansion in the use of air warfare and flying missiles and these technological advances posed a grave threat to civilians and humanitarian workers.

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Motivations and Barriers to Treatment Uptake and Adherence Among People Living with HIV in Australia: A Mixed-Methods Systematic Review. Isoproterenol significantly increased the plateau duration in the presence of nicorandil, but further abbreviated it in the presence of carbachol. The first branch of the lateral plantar nerve was indistinguishable from the trunk of the tibial nerve descending medially to between the lateral plantar and calcaneal nerves. It was also found that the CYP2E1 increased 2-4 times in rats with acute renal failure induced by uranyl nitrate (U-ARF) compared with those in control rats. Regarding the prognostic factors, we even found a significantly higher percentage of Stage I epithelial ovarian cancer in the study group, with no difference in the mode of detection. We conclude that, under physiological conditions, cGMP is a stimulatory second messenger for renin release.

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Cell lysates of corneal epithelial cells in rabbits stimulated with keratinocyte growth factor (KGF) and hepatocyte growth factor (HGF) were processed for Western blot using antibodies to phosphorylated p44/42 MAPK. Moreover, severe obesity was associated with less mortality risk. Under constraints of image points, the angular distance between their re-projecting vectors and the image of absolute conic (IAC), nonlinear optimization is used to solve parameters of IAC. Intestinal function and injury in acquired immunodeficiency syndrome-related cryptosporidiosis. N-(p-Chlorophenyl)-3,3-diphenyl-4-(beta-phenylstyryl)azetidin-2-one. Here, we examine the possibility that noncoordinate regulation of ENaC subunits may represent another mechanism in the arsenal of physiological responses to diverse stimuli.

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To compare Nd:YAG capsulotomy rates following implantation of two diffractive trifocal intraocular lenses (IOLs). We evaluated the ability of these hybridomas to induce third order or effector Ts (Ts3) to suppress the contact sensitivity response against the hapten 4-hydroxy-3-nitrophenyl acetyl (NP). A QTL that enhances and broadens Bt insect resistance in soybean. A new era in periodontal research and practice is being defined along the following lines: Better understanding of disease. Individual differences in implicit motor learning: task specificity in sensorimotor adaptation and sequence learning.

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Blood loss produces rapid increases in IL-1 alpha and IL-1 beta mRNA expression among pulmonary cell populations. More patients were attack-free at follow-up after a positive (7 of 16) in comparison to a negative (5 of 15) test. Equilibrium factors between radon and its progeny and thoron and its daughters were evaluated in the studied atmospheres. Nine hematomas imaged after this time all showed a characteristic concentric-ring configuration, with a thin, dark peripheral rim on all pulse sequences and a bright inner ring most distinctive on T1-weighted images. Cardiovascular disease has emerged as a leading cause of morbidity and mortality in this population, and is likely related to both an increased prevalence of traditional cardiovascular risk factors and HIV-specific factors associated with antiretroviral therapy, chronic inflammation, and direct viral effects. Two hundred and twenty-two breast cancer patients (229 breasts) treated between 1983 and 1996 with breast conserving therapy including a brachytherapy boost were scored on the occurrence of teleangiectasia. It is thus not clear how distinct the Rif-driven pathway for filopodium formation is from the one mediated by Cdc42. Intraoperative findings, operative time, and outcome were also recorded.

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