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Nifelat (Nifedipine)

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Nifelat belongs to the group of Calcium Channel Broker (CCB). This medication is used to control chest pain (angina) and hyper tension (high blood pressure). Nifelat was produced by Bayer, a reputed German pharmaceutical company. The initial studies on the drug were undertaken in the year of 1970. This drug is approved by FDA.

Other names for this medication:
Afeditab, Bresben, Calcheck, Calcigard, Cardicon, Casanmil, Chronadalate, Conetrin, Depicor, Glopir, Macorel, Menoprizin, Nedipin, Nifedipin, Nifedipino, Nifin, Nipidin, Nycopin, Oxcord, Pressolat, Sidalat, Siopelmin, Tenif, Viscard, Xepalat

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Nifelat OROS. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Nifelat and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Using Mycobacterium marinum as a model, we performed a genome-wide screen to identify mutants whose ability to inhibit phagosome maturation was impaired, and we succeeded in isolating a comprehensive set of mutants that were not able to occupy an early endosome-like phagosomal compartment in mammalian macrophages. The current model for autodisplay suggests a mechanism that allows a passenger protein to be translocated across the outer membrane by coordinate action of a C-terminal beta-barrel and its preceding linking region. Alkaloids of Ervatamia pandacaqui Pichon (Tabernaemontana pandacaqui Poir.), Apocynaceae. Proximal aortic stiffness is related to left ventricular function and exercise capacity in patients with dilated cardiomyopathy. To validate the data from cDNA microarrays on clinical prostate cancer specimens, a tissue microarray of specimens from 26 prostates with benign prostatic hyperplasia, 208 primary prostate cancers, and 30 hormone-refractory local recurrences was constructed and used for immunohistochemical detection of protein expression. Some preliminary data on the structure of quail (Coturnix coturnix) hemoglobin. Family accommodation of obsessive-compulsive symptoms: instrument development and assessment of family behavior. Studies on the excretion of guanethidine (Ismelin) metabolites in the urine of hypertonics.

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The Center for Epidemiologic Studies-Depression (CES-D) scale was used to assess depression. Our novel analytical approach represents to be a potentially useful tool to obtain particle-specific lipid components of lipoproteins. Observations on the diagnosis and management of segmental arterial obstruction from arteriosclerosis. We suggest that this drug may be a useful adjuvant in difficult cases of status convulsivus in neonates. Although the significant cohort effects may give a caution for a continuous increase of colorectal cancer incidence, the future trend may be influenced by the period-related factors. Bolus intravenous injection of phosphorothioate oligonucleotides causes hypotension by acting as alpha(1)-adrenergic receptor antagonists. Evolution of the schistosomal hepatic lesions in mice after curative chemotherapy.

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After decannulation, the esthetic result in patients that underwent the dilatational tracheotomy can be considered excellent. Additional evidence is needed to clarify the role of this blood purification technique for the treatment of septic shock. Four common extracellular proteins (EspA, EspB, EspD, and Tir) were regulated by both IHF and Ler in EHEC EDL933 and EPEC E2348/69. Analytical relationships between NMR order parameters and conformational entropies are derived, and the possibility to extract the latter from NMR experiments is discussed. The role of hydroxyurea (HU) in the treatment of HIV infection remains controversial. Since the joint statement of the German Societies of Oto-Rhino-Laryngology, Head and Neck surgery, of pediatrics and of anesthesiology regarding the necessity of coagulation tests prior to adenoidectomy or tonsillectomy in children we wanted to know whether blood tests have any effect for ear operations. Two of the most remarkable properties of these compounds are their structural and physiological diversities. Implications of the findings for future research and for identifying high-risk subgroups of adolescents for purposes of intervention based on timing and pattern of escalation are discussed. Both trainees and trainers have stressed the importance of change in vocational training. Similarly, substitution of four Ser/Thr residues between positions 334 and 339 results in a deficit in desensitization but again no decrease in internalization, suggesting that phosphorylation at either site evokes receptor internalization, whereas maximal desensitization requires phosphorylation at both sites.

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The concentration of 1-(2-tetrahydrofuryl)-5-fluorouracil (FT), 5-fluorouracil (5-FU) and uracil in blood, the bladder tumor tissue and the bladder mucosa after oral administration of 600 mg per day of UFT for 7 consecutive days was examined in 10 cases of bladder tumors. Thus, of the diamines evaluated, cadaverine elicited both antennal and behavioral responses comparable to that of putrescine and will be studied further as a potential attractant for pest Anastrepha species. By contrast, DMAA did not influence the number and location of gamma-tubulin signals in interphase cells. Furthermore, MALAT1-targeted therapies showed great potential in enhancing the radiotherapeutic effect on ESCC. Percutaneous nephrolithotomy is a safe and relatively efficacious mode of managing pediatric renal calculi. The studies included clinical examination, audiological findings, radiological studies and craniometrical X-ray measurements. A case of complete median cleft of the upper lip and alveolus with holoprosencephaly is presented. The effects of CETP on atherogenesis are currently unpredictable, and they are likely to depend on the metabolic context. The internal bony defect was at the junction of the frontal and ethmoid bones, in front of the crista galii, in the floor of the anterior cranial fossa. The degree of induction is unpredictable due to factors such as the variable quality and quantity of constituent(s) in SJW preparations.

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The present study helps to improve our knowledge of waste leachate organic composition. Information-seeking behavior of faculty in one school of public health. Many of these conditions are associated with intractable epilepsy. Upon hybridization with a specific target, the TSPs immobilized on the GNP surface hybridized with the corresponding target miRNA to form DNA-RNA heteroduplexes, and the DSN can recognize the formed DNA-RNA heteroduplexes to hydrolyze the DNA in the heteroduplexes to produce a specific fluorescent signal corresponding to a specific miRNA, while the released target miRNA strands can initiate another cycle, resulting in a significant signal amplification for sensitive miRNA detection. To investigate the role of TCEAL4 in ATC carcinogenesis, we examined expression levels of TCEAL4 in ACLs as well as in other types of thyroid cancers and normal human tissue. Stimulation of brain homogenates with a mixture of neurotransmitters increased the association of lobGRK2 with membranes and with G(beta). The survey reveals that mometasone furoate, a new inhaled steroid with topical activity, has the greatest binding affinity for the glucocorticoid receptor, followed by fluticasone propionate, budesonide, triamcinolone acetonide, and dexamethasone. Data Library: Breast cancer survival rates are going up, largely due to early detection and diagnosis. Although this was a small study, systematic and careful monitoring of ARI, antibiotic use, and asthma and atopic diseases did not indicate that receipt of antibiotics early in life led to subsequent asthma or atopy at 5 years. Angiographic results from the PRISM-PLUS trial (Platelet receptor inhibition for ischemic syndrome management in patients limited by unstable signs and symptoms).

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The modified dosing schedule was prospectively tested in a subsequent population of 18 pediatric patients after cardiac surgery. Effects of temperature, light, and nutrition on the sensitivity of the male Rana pipiens to exogenous chorionic gonadotropin. Detecting overlapping coding sequences with pairwise alignments. A genome-screen experiment to detect quantitative trait loci affecting resistance to facial eczema disease in sheep. In this study, the next generation of InGaN near-UV laser diodes (NUVLDs) emitting in the 370-375-nm range have been evaluated as laser sources for cuvette-based flow cytometers. A comparison of flashbacks and ordinary autobiographical memories of trauma: cognitive resources and behavioural observations. A human immunoglobulin G preparation, enriched in antibodies to lipopolysaccharide (LPS) Pseudomonas aeruginosa antigens (PA-IGIV) and murine monoclonal antibodies (MAb) to P.

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A prospective study was undertaken to assess the efficacy and toxicity of conformal proton-beam radiotherapy for early-stage, medically inoperable non-small cell lung cancer. The role of multislice CT in polytrauma management, differential diagnosis and insurance aspects. Bronchial responsiveness to nonantigenic bronchoconstrictors in awake sheep. The constant-bandwidth hot-wire anemometer can be used in measurements of high-frequency variable flows characterized by a wide range of velocity changes. Cortical and subcortical multiunitary activities (MUA) and EEG were simultaneously recorded in baboons rendered photosensitive by a subconvulsant dose of DL-allylglycine. The provided comonomers define the character of the surface and its behaviour towards biomolecules and biosystems, such as proteins and cells. We will conclude our review by a description of potential gene therapeutic and hormonal approaches and of new developments in the design of effective vaccines.

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As an alternative to standard surgical therapy, the patient was treated with selective intravenous low-dose infusion of streptokinase at doses of 5,000-20,000 units/h. Editorial comment on: Thirty-day mortality after nephrectomy: clinical implications for informed consent. However, more literature exists on cognitive impairment in schizophrenia than in bipolar disorder. Previous studies have provided useful information regarding thoracic pedicle anatomy, but this information is difficult to apply intra-operatively. Transcultural child psychiatry: its history, present status and future challenges. Labour is associated with increased expression of type-IIA secretory phospholipase A2 but not type-IV cytosolic phospholipase A2 in human myometrium. Annular geometry was evaluated by diameters, areas and their percentual shortening. In diabetic rats cured of their diabetes with transplants of fetal pancreatic tissue beneath the renal capsule, ventromedial hypothalamic (VMH) lesions do not produce the characteristic rise in food intake nor do they significantly increase serum insulin.

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The BK-channel antagonist paxilline possesses significant anticonvulsant activity in both picrotoxin and pentylenetetrazole seizure models, an effect that may be related to the seizure-dependent gain-of-function in BK channel previously observed in neocortical neurons in vitro. The subunit molecular weight of the enzyme was 93,000 as determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. In this study, we show that the complex stimulated in vitro transcription from nucleosome templates in an activation domain-dependent manner. Condensin is required for chromosome arm cohesion during mitosis. Only when both the myristoyl moiety and the ED are excised does the interaction fall to zero in the case of the acidic membranes, with very small residual binding still detectable in the presence of neutral membranes. In this paper, we revisit the issue of ideal therapeutic BP target in diabetes patients with hypertension. Statin monotherapy is efficacious, well tolerated and safe in the short-term, although long-term safety remains unclear. Research on oxidative phosphorylation in the brain of animals subjected to high temperature. Thirteen subjects performed an incidental encoding task for words presented auditorily during the inhalation of a subanesthetic dose of isoflurane. It is a well described but rare complication of surgical abortions, and tends to have an aggressive course.

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Mapping of five subtype genes for muscarinic acetylcholine receptor to mouse chromosomes. We examine the projection of this SA angle onto the transverse, coronal, and sagittal planes to gauge some measure of rotation, lateral tilt, and anterior tilt with respect to the patient. Functionally, the corresponding proteins were divided into four groups. Error-resilient video communications over CDMA networks with a bandwidth constraint. Such an approach is advantageous, compared to postfunctionalization of premade graphene, as both functionalization and exfoliation occur at the same time, meaning that monolayer or few-layer graphene can be functionalized and stabilized in situ before they aggregate. The induction of class I HLA by interferon-alpha is independent of bisoprolol dose equivalent the cell cycle, but the expression is enhanced by a G1/S block. CagA tyrosine phosphorylation and interleukin-8 induction by Helicobacter pylori are independent from alpAB, HopZ and bab group outer membrane proteins. The use of middleware to develop widely distributed healthcare information systems (HIS) has become inevitable. This review focuses on facial hyperpigmentation and outlines the most common skin disorders and treatment options. Analyses of serum lipoprotein(a) and the relation to phenotypes and genotypes of apolipoprotein(a) in type 2 diabetic patients with retinopathy.

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One hundred women with a mean age of 52.5 years (91 evaluable) were randomly and blindly assigned to either a sequential estradiol-norethisterone acetate regimen or placebo for 3 months, after which all participants received open HT for a further 3 months. The distribution of focal adhesion sites and of the cytoskeletal protein vinculin was determined in large, fused, multinucleated PC12 cells. In 6 patients the mucosal wave was found stroboscopically to be abnormal. The alpha subunit is comprised of four homologous domains containing six transmembrane alpha helices (S1 through S6) and additional membrane-associated segments (SS1/SS2). Triatoma dimidiata (Latreille, 1811): a review of its diversity across its geographic range and the relationship among populations. Although both activin and glucocorticoids are notable regulators of FSHbeta by themselves, we find that cotreatment results in a synergistic interaction on the mouse FSHbeta promoter at the level of the gonadotrope using transient transfection of a reporter gene into the LbetaT2 immortalized gonadotrope-derived cell line.

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The action of cortistatin (CST), a novel cyclic neuropeptide, as an noroxin 400 mg fiyat anti-inflammatory factor has been studied, but few investigations have explored the immunomodulatory role of CST in transplantation. Invasive Kingella kingae infections in children: clinical and laboratory characteristics. Industry still divided over whether SNFs may refuse to admit Medicare patients based on payment concerns. A legally approved personal dosemeter for photon and beta radiation based on direct ion storage. No relation was found between circulating plasma levels of TNF-alpha and levels after in vitro LPS stimulation. The treatment of demerol addiction with adrenal cortical extract and glycyrrhiza (licorice): report of a case. Epidermal growth factor (EGF) has a neurotrophic activity on developing midbrain dopaminergic neurons. CaBP binds to the longer peptide melittin, but does not bind to mastoparan, the binding enthalpy being endothermic in nature. Nanoengineering of the coated colloids and microcapsules allows precision control over optical, mechanical, and catalytic properties to achieve sensitive response using a combination of polymers, fluorescent indicators, and glucose-specific proteins.

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