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Primacal (Calcitriol)
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Primacal

Primacal is a hormonally-active, synthetic vitamin D analog prescribed to treat hypocalcemia, osteoporosis, and the prevention of corticosteroid-induced osteoporosis. Systemic Primacal is FDA indicated to control hypocalcemia in patients on chronic renal dialysis, secondary hyperparathyroidism in those with chronic kidney disease not yet on dialysis, and hypocalcemia in patients with hypoparathyroidism and pseudohypoparathyroidism.

Other names for this medication:
Admax, Alfabond, Alfacal, Alfacip, Arachitol, Biocitral, Bonetuf, Calbec, Calbovic, Calcimet, Calcor, Caldikind, Calfa, Calgel, Calosto, Calsure, Carcal, Dmcal, Estovon, Fovit, Koncal, Lctrol, Netxod, Novadee, Ostriol, Politrol, Qpcal, Rockbon, Rolsical, Solbiocal, Sorvate, Tobalt, Trolec

Similar Products:
Levlen, Adalat, Pepcid, Caverta, Mircette

Also known as: Calcitriol

Description

Generic Primacal is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Primacal are intestine and bone. Generic Primacal receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Primacal may also act on the kidney and the parathyroid glands. Generic Primacal is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Primacal has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Primacal, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Primacal in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Primacal produces other independent beneficial effects. Primacal is also known as Calcitriol. Generic Primacal treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Primacal is Calcitriol. Brand name of Generic Primacal is Primacal.

Dosage

Generic Primacal is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Primacal suddenly.

Overdose

If you overdose Generic Primacal and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Primacal are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Problems in older adults have not been reported with intake of normal daily recommended amounts. Studies have shown that older adults may have lower blood levels of vitamin D than younger adults, especially those who have little exposure to sunlight. Your health care professional may recommend that you take a vitamin supplement that contains vitamin D.

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Microsomal triglyceride transfer protein inhibitors: discovery and synthesis of alkyl phosphonates as potent MTP inhibitors and cholesterol lowering agents. Addressing these issues is critical because even a modest association between neck manipulation and cervical artery dissection could translate into a significant number of avoidable dissections given the widespread use of neck manipulation by providers from various backgrounds. To our knowledge there is no multi-institutional report on prepubertal testicular tumors in Korea to date. Under these same experimental conditions, however, VPA neither inhibited GSK-3 activation nor hindered GSK-3 mediated Tau phosphorylation. Clinical characterisation of severe hypoglycaemia--a prospective population-based study. The purpose of this study was to compare the effectiveness of a consultative model of intervention with that of direct-indirect intervention for meeting goals of preschool students with mild motor delays. Disruption of vascular homeostasis can lead to the development of endothelial dysfunction which in turn contributes to the early and late stages of atherosclerosis. These observations identify astrocytic end-foot processes plastered at the vessel wall as a center for purinergic signaling. Their babies did not have any evidence of minor or major malformations, and showed normal neurological development at 6 and 2 years of follow-up, respectively. The VAS and the bladder problem question of the KHQ show the greatest promise as single-item scales to assess problem intensity in OAB patients.

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Lasso repair of SLAP or Bankart lesions: a new arthroscopic technique. Taking the Local Health Administration Committees (CLAS) from the second Fujimori government (1995-2000) as an example, it is shown that for self-motivated rural communities to work in harmony with the state, there must be willingness to adapt to the varying levels of intra-community differences, social integration and social support. This, and the observation that c i remained relatively constant as irradiance was varied, suggest that changes in c i played a minor role in mediating the stomatal response to light.The ecological significance of the seasonal changes in stomatal response to light is discussed. Secondly, a meta-analysis was performed comparing ICG to intraoperative cholangiography (IOC) for identification of biliary structures. Bag-in-the-lens implantation was highly effective in preventing PCO in vitro and in vivo provided the anterior and posterior capsules were secured properly in the peripheral groove of the IOL. These findings suggest that NO-producing neurons constitute a subclass that is distinct from that of catecholaminergic neurons. These cases presented with varying types of eyelid abnormality associated with the systemic disease.

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A novel predictive control algorithm and robust stability criteria for integrating processes. A nested polymerase chain reaction (PCR) was used to detect human cytomegalovirus (HCMV) DNA in serum of patients with adult T-cell leukemia (ATL). The molecular mechanisms of the asterin action on the lymphocyte transformation characterized by an increase in the metabolism and synthesis of the membrane phospholipids are likely associated with the control of their free radical processes. The nature and purity of the fraction were confirmed by electron microscopy. Unexplained elevated maternal serum alpha-fetoprotein and/or human chorionic gonadotropin and the risk of adverse outcomes. The active electrode was placed over the corresponding somatosensory cortex at C4 according to the 10-20 EEG system and the reference electrode at the forehead above the contralateral orbita. The aim is not to denigrate one or the other but to share things between these two families of anticoagulants. Intramedullary nailing is the treatment of choice for patients with femoral shaft fractures.

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Spontaneous vegetative endocarditis due to Enterococcus faecalis in a rottweiler puppy. Patient satisfaction of emergency nursing care in the United States, Slovenia, and Australia. Recent studies have shown that long noncoding RNAs (lncRNAs) play pivotal roles in the initiation and progression of cancer, including esophageal squamous cell carcinoma (ESCC). Sedimentation field flow fractionation (SdFFF) has been described as an effective tool for cell separation, respecting integrity and viability. Irrelevant auditory attention shifts prime corresponding responses. Recent studies have demonstrated its involvement in developmental patterning and in the regulation of various genes implicated in chromatin remodelling. Comparison of our data with previous studies suggests that the putative relationship between semen quality and 2D:4D may have been driven by the inclusion of severely oligozoospermic men within the original subject group. Studies on supercritical CO2 fluid extraction for ginkgolic acids in the epicarp of Ginkgo biloba. The second and more quantitative approach generates a grid of Langevin dipoles, which are polarized by the TSA, and then uses the grid to bind the TS.

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A variety of binding sites for endotoxin (LPS) have been identified on leukocytes. The activity of lupeol (5), 29-hydroxylupeol (6) and 29-hydroxylupenone (7) might be involved with the prostanoid synthesis. Understanding differences in physiological and metabolic responses between the leaf and spike organs during drought can help us develop high yielding cultivars for environments where terminal drought is prevalent. Hypertrophic osteoarthropathy (HOA) is a condition that accompanies many seemingly unrelated diseases. A history of the behavior program at the Jackson laboratory: an overview. Reliability of EUCLIDIAN: an autonomous robotic system for image-guided prostate brachytherapy. The supine subcostal modification of the thoraco-abdominal incision. To describe breed-specific causes of death in all instances of canine mortality recorded in the Veterinary Medical Database (VMDB)(a) between 1984 and 2004.

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Regulation of leg size and shape: involvement of the Dachsous-fat signaling pathway. A simple topological identification method for highly (3,12)-connected 3D MOFs showing anion exchange and luminescent properties. Moreover, in the mutant follicles patches of columnar follicular epithelium differentiate locally although this type of epithelium forms normally only around the oocyte. In contrast with basal activity, pronounced age-related changes in response to specific stimuli were detected in all endocrine functions. Through a Bayesian spatial statistical method, a time-dependent approach for groundwater vulnerability assessment is developed to account for both the recent status of groundwater contamination and its evolution, as required by the European Union (Groundwater Directive, 2006/118/EC). Illumination of dark-grown Myxococcus xanthus with blue light leads to the induction of carotenoid synthesis.

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HPLC indicates the presence of several forms of GAL-like peptides. As a result of reading this manuscript the reader will (1) gain an understanding of types of perceptual scales and how to develop the set of vocal characteristics to be used in distinguishing patients with UVFP and those without, (2) learn which vocal characteristics listeners are able to use to successfully distinguish between patients with UVFP and those without and (3) understand the possible role for perceptual ratings in tracking changes in vocal characteristics in subjects over time following treatment or spontaneous recovery of function. Synthesis and evaluation of novel pyrimidine-based dual EGFR/Her-2 inhibitors. The effect of the dengue non-structural 1 protein expression over the HepG2 cell proteins in a proteomic approach. Stimulated Brillouin scattering in dispersion-decreasing fiber with ultrahigh-speed femtosecond soliton pulse compression. obtusa leaves was identified as beta-thujaplicin (C10H12(O2)) by spectroscopic analyses. Evaluation of stroke services in Anglia Stroke Clinical Network to examine the variation in acute services and stroke outcomes. Muscle atrophy is a common consequence of catabolic conditions like kidney failure, cancer, sepsis, and acute diabetes. FGFR1 is independently required in both developing mid- and hindbrain for sustained response to isthmic signals.

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Targeted modification of homogalacturonan by transgenic expression of a fungal polygalacturonase alters plant growth. A polyclonal assay for T helper function involving T-B cell contact mediated by L3T4 molecules. Molecular orientation of ultrahigh molecular weight the medication cardura polyethylene induced by various sliding motions. The complement system plays one of the leading roles in the pathogenesis of autoimmune diseases, wherein, not, as was earlier considered, because of the absence of an adequate clearance of immune complexes, but as a result of maintaining immunologic tolerance. We have also reported the anti-tumor efficacy of combination treatment with caffeine and valproic acid against osteosarcoma primary tumors in a cell-line orthotopic mouse model. tenella have been constructed in Escherichia coli using the expression vector lambda amp3.

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(18)F-FDG-PET is a useful diagnostic tool in patients with unclear systemic inflammation and FUO. Anti-leukemia effect of perillyl alcohol in Bcr/Abl-transformed cells indirectly inhibits signaling through Mek in a Ras- and Raf-independent fashion. The resulting articles were independently subjected to clear inclusion and exclusion criteria by two reviewers as follows. For dung beetles, abundance of smaller species was higher at the island site, whereas that of large species did not differ between the lakeshore and island sites. Musculoskeletal responses of 2-year-old Thoroughbred horses to early training. The distribution of dendritic cells in the synovial fluids of patients with arthritis. Temporal changes in food preferences of wood mice (Apodemus sylvaticus L.). An Exemplar-Based Multi-View Domain Generalization Framework for Visual Recognition. Prophylaxis of acute respiratory virus infections using nucleic acid-based drugs. The Endologix developed an aortoiliac stent graft system that is different than the conventional implantation technique (Nellix, EVAS-endovascular aneurysm sealing system).

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A questionnaire was mailed to 110 men who underwent BMG urethroplasty between January 1, 1997 and August 31, 2002. IFP technology makes it possible to view dynamic processes in living cells, but extended observation, using fluorescence microscopy (both wide-field and confocal), can result in significant light energy exposure. No evidence is available on the optimal treatment of acute cystitis and pyelonephritis in patients with DM. Here we show that the ParF partition protein specified by the TP228 plasmid is a ParA ATPase that assembles into extensive filaments in vitro. So far 5 monthly injections from November to March are recommended. Flank Hernia ventolin expectorant generic name Repair with Suture Anchor Mesh Fixation to the Iliac Crest. Repression of two different target genes could be distinguished by specific mutants, further supporting the notion of at least two different Myc repression mechanisms. The 3-methane-sulfonamide analogue (18) had a higher affinity for the D2 receptor than DPDA and was more selective for the D2 receptor. Nicotine use and dependence is very high in patients with schizophrenia.

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Focus group on licensed practical nurse scope of practice at National Council of State Boards of Nursing. The presence of a PDZ domain suggests that MYO18A may interact with other partners to perform muscle-specific functions. Comparative studies with C3H/HeN and C3H/HeJ mice demonstrated the strong dependency of the LF-LPS signal on TLR4. The models suggest the potential gains from controlling major established risk factors could be substantial in South Asians and greater than in Europeans. Differential utilization of systemic and enteral ammonia for urea synthesis in control subjects and ornithine transcarbamylase deficiency carriers. Our data suggest that in addition to well-known ER-directed quality control, tyrosinase is also subject to post-Golgi quality control. The renographic evaluation was first performed after ingestion of the daily therapy of angiotensin II receptor antagonist alone (Sartan renography) and was repeated within 7 d after the acute addition of 25 mg of captopril to chronic treatment with angiotensin II receptor antagonist (captopril-Sartan renography). The role of d-norfenfluramine in the indole-depleting effect of d-fenfluramine in the rat. tenuis within the cervical spinal cord of a horse with scoliosis and cutaneous analgesia. To investigate the mechanisms underlying sorting of proteins to SVs, fluorescent chimeras of vesicle-associated membrane protein (VAMP) 2, its highly homologous isoform VAMP1 and synaptotagmin I (SytI) were expressed in hippocampal neurons in culture.

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These data suggest that the dimeric capsid protein functions as a basic building block in the assembly process of flaviviruses. Hematologic and/or serum chemical analyses were done on a total of 27 non-tranquilized adult and juvenile wild sea otters, 66 tranquilized adult and juvenile wild sea otters, and 26 wild sea otter pups. This is the first study that attempts to identify the proteome of Z. Portulaca oleracea seedlings avoid growing how do you take albendazole syrup in the direction of neighbouring plants even when they are very small or remote. Structure of the mouse galectin-4 N-terminal carbohydrate-recognition domain reveals the mechanism of oligosaccharide recognition.

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The potential for a selective cyclooxygenase-2 inhibitor in the prevention of liver metastasis in human colorectal cancer. We describe a series of four patients with recurrent ovarian carcinoma and proximal intestinal obstructions treated with a bypass stapled side-to-side gastrojejunostomy at the time of secondary cytoreduction or surgical palliation. Extended at-home bleaching of tetracycline-stained teeth with different concentrations of carbamide peroxide. A haematologist/transfusion specialist was assigned as a member of the team. TD-DFT and even semiempirical ZINDO calculations reproduce the trends of longest wavelengths absorption bands and allow the assignment of these transitions to possess largely charge-transfer character from the adjacent phenothiazinyl moieties to the central thienyl unit.

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