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Rozac (Adapalene)

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Rozac is used to treat acne. It may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Rozac belongs to a class of medications called retinoids. It works by affecting the growth of cells and decreasing swelling and inflammation.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Hytrin, Revia, Prandin, Zyloprim, Lodine, Lasix

Also known as: Adapalene


{name} (adapalene) is a topical medicine (a medication that is applied to the surface of the skin) similar to vitamin A. It helps the skin to renew itself.

{name} is used to treat severe acne in people who are at least 12 years old. It works by decreasing acne formation.


Follow the directions for using this medicine provided by your doctor. Use Rozac exactly as directed. Rozac is best applied after washing and drying your skin. Apply a thin layer of gel to the affected areas once daily at bedtime. Avoid the eyes, lips and nose. Do not allow this preparation to come into contact with the mucous membranes (e.g. mouth, vagina, inside of nose etc.). Try not to touch the treated areas overnight. Do not use any harsh soaps or exfoliants while you are being treated with Rozac. Rozac should not be used on broken, sunburnt or infected skin. You may notice a slight change of colour of the skin you are applying this preparation to. This is only temporary and should return to normal soon after finishing treatment with Rozac. Continue using Rozac until no new acne spots appear. You may need to use it for several months. You should notice some clinical improvement after 4-8 weeks and more improvement after further use. There may be a worsening of acne during the first few weeks of therapy because Rozac promotes the growth of pimples that have begun to form but are not yet visible. Therefore, treatment should not be stopped if acne appears to be worsening. Use a sunscreen cream and wear protective clothing if exposure to strong or prolonged sunlight cannot be avoided. Weather extremes such as wind or cold may also be irritating.


If you overdose Rozac and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Rozac dosage information

Side effects

The most common side effects associated with Rozac are:

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There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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The persistence of protection from meningococcal disease following immunization with serogroup C meningococcal (MenC) glycoconjugate vaccines in infancy is short-lived. Toxoplasma gondii and fungi are the leading causative organisms in patients after allogeneic SCT, but also viruses such as herpes simplex virus or JC virus may be detected in these patients. No changes in GM-CSF-induced p38 MAPK phosphorylation were observed. In order to understand complex vortical flows in large data sets, we must be able to detect and visualize vortices in an automated fashion. The main reasons were stoma-associated morbidity and nutritional deficiency syndromes.

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Bone tissue engineering on calcium phosphate-coated titanium plates utilizing cultured rat bone marrow cells: a preliminary study. The data presented here justify further pharmacogenetic studies for potentially optimizing recommended drug dosages and evaluating relationships with disease processes. In the coming decade, scientific and clinical advances are to be expected in several fields such as nerve injuries including brachial plexus lesion, microsurgery, flexor tendon injuries and tendon transfer. Comparison of clinical, radiographic and immunological parameters of teeth and different dental implant platforms. This paper discusses the technical aspects of a newly designed circular retractor system for endoscopic and microsurgical spinal interventions (SpineGate) and presents first clinical results in a series of 20 consecutive patients. Intrauterine growth restriction increases morbidity and mortality among premature neonates. This study was undertaken to determine the apoptotic potential of lactosylceramide and the effect of cyclooxygenase inhibitors and cAMP activators on lactosylceramide-induced apoptosis in primary amnion and WISH cells. These microorganisms did not cause any detectable manifestation of disease, despite being potential pathogens. pseudolongum strain Patronus exerts an effect on a biomarker of oxidative damage by reducing the susceptibility to oxidation of proteins in the colon and the small bowel. Certain ethnic groups, such as Ashkenazi Jews and those of Mediterranean origin, are especially liable to pemphigus.

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In the last decade, the identification of appropriate surrogate models that reflected the antiresorptive potencies of bisphosphonates, such as Dictyostelium slime molds and macrophages, helped overcome this problem and proved to be instrumental in elucidating the molecular pathways by which these compounds inhibit osteoclast-mediated bone resorption. Inflammatory cells and fibroblasts were observed in the adventitial layer of collared arteries 4, 7, 14 and 28 days after injury. Notably, the shift in the coreceptor usage from CCR5 to CXCR4 is associated with an increase in the net positive charge in the V3 region. Body weight at the time of RTx and weight gain 1 year after RTx, but not cardiovascular complications and allograft loss, are related to the ACE I/D genotype of RTx recipients. Specific disruption of spatial behaviour in rats by central muscarinic receptor blockade. Evolution of the stimulation threshold and myocardial tissue changes during intracavitary electric stimulation. Simultaneous endovascular exclusion of thoracic aortic aneurysm with open abdominal aortic aneurysm repair. This ubiquitous epiphenomenon is a major complication in several CNS pathologies, including head trauma and stroke. The purpose of this study was to investigate the importance of the ephrin system in OA subchondral bone osteoblasts.

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Marketing orientation in hospitals: findings from a multi-phased research study. Previous research has shown fluid replacement beverages ingested after exercise can affect hydration biomarkers. The covalent modification of chromatin provides an attractive mechanism for establishing and maintaining stable states of gene activity. 125I-labeled calmodulin binding to Ca/calmodulin protein kinase was also demonstrated using filters containing Ca/calmodulin protein kinase transferred from polyacrylamide gels after two-dimensional gel electrophoresis. We performed genetic analysis of 134 patients in Taiwan with HTG (53 with HLP and 81 without HLP). Preovulatory serum gonadotropin levels in hMG stimulated menstrual cycles in pregnant and nonpregnant patients. When ApoG2 was combined with ADM, increased cytotoxicity and apoptosis were observed in SMMC-7721 cells compared to treatment with ApoG2 alone.

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99mTcN(NOEt)2 may be a gamma imaging agent better than 99mTc-MIBI for nasopharyngeal carcinoma imaging. The purpose of this study was to examine the relationship between alcohol exposure in pregnancy and offspring conduct disorder symptoms in adolescence and to examine how much this increasingly known association may be mediated by maternal and paternal externalizing diagnoses, including lifetime maternal and paternal alcohol and drug abuse/dependence diagnoses as well as antisocial disorders. Mutations along a TET2 active site scaffold stall oxidation at 5-hydroxymethylcytosine. A literature review was carried out in PubMed following the PRISMA criteria. Both bathing of the yolk-sac fry in thiamine hydrochloride (1000 mg l-1, 1 h) and a single intraperitoneal injection given to the female brood fish (100 mg kg-1 fish) during the summer 3 mo before stripping were shown to elevate the whole body total thiamine concentration in the fry. Gastric emptying of solid or liquid with oesophageal infusion was not significantly different from that with gastric infusion. Evidence that phospholipids play a key role in pre-beta apoA-I formation and high-density lipoprotein remodeling.

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Observer ratings of perceived qualities and effects of lifelike (fake) plants while spending time in the waiting room. Gaps identified in our understanding of uncertainty include: a limitation in the availability of basic measurements, a lack of knowledge of the environmental processes, an inability to predict the effects of mixtures, the aetiology of disease and devising procedures for optimal resource allocation in impact assessment. Outcome after three years of laronidase enzyme replacement therapy in a patient with Hurler syndrome. Decreased levels of dehydroepiandrosterone sulphate in severe critical illness: a sign of exhausted adrenal reserve?. The data collected included patient demographics, the tumor histology and stage, the type of treatment for both CLL and lung carcinoma, the presence of a third malignancy, the disease status at last follow-up, and the first site of relapse. The retrograde tracer FluoroGold (FG), administered through the probe after cessation of dialysis sampling, was observed within identified noradrenergic cells primarily within the A1 and A2 cell groups.

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Sugarcane transcriptome analysis in response to infection caused by Acidovorax avenae subsp. Effects of baby walkers on motor and mental development in human infants. Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial. In this study, we found that ATRA treatment of the APL cell line NB4 induced the expression of CD52, both at transcriptional and translational levels. Evaluation of three immunoserological techniques in the detection of porcine trichinellosis. Neutron dose measurement and evaluation techniques in criticality accident conditions using a thermo luminescence dosemeter (TLD) was glimepiride tablet uses in telugu studied at the Transient Experiment Critical Facility (TRACY) of Japan Atomic Energy Research Institute (JAERI). Diuretics and carbohydrate metabolism: effects of a single dose of hydrochlorothiazide, furosemide and ethacrynic acid on the tolbutamide test in senile subjects. Prospective, controlled study of students in a technical training facility.

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The differences in prostate definition in the anterior base region suggest that the commonly reported underdose may be due to overestimation of the prostate in this region by CT. These results suggested that we have successfully prepared honokiol-loaded micelles in an improved method which is safer and more efficient. All observational studies that evaluated the association between urinary prograf 5 mg price bladder risk and the petroleum industry were reviewed. Over the past decade and a half, a substantial literature has documented age-dependent variations in breast cancer care. In this study, we show that cigarette smoke extract (CSE) induced MMP-2 protein expression and increased MMP-2 gelatinase activity of normal lung fibroblasts. Letter to the Editor: Obesity Severity and Duration Are Associated With Incident Metabolic Syndrome: Evidence Against Metabolically Healthy Obesity From the Multi-Ethnic Study of Atherosclerosis.

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