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Ultram (Tramadol)

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Ultram is an oral medication that is used to help relieve ongoing moderate to moderately severe pain. Ultram is similar to opioid (narcotic) analgesics. It works in the brain to change how your body feels and responds to pain.

Other names for this medication:
Acuvin, Arodol, Atdol, Contradoc, Contramal, Cosdol, Dolfre, Drobit, Leedol, Medol, Movon, Mydol, Nobligan, Nopidol, Nosdol, Omodol, Painex, Pentazen, Ramcet, Sayodol, Sedate, Siatram, Soztram, Standol, Tacil, Taramol, Taxidol, Tramafen, Tramazac, Tramazol, Tramex, Tramol, Trandy, Trapain, Tromfil, Trydol, Ultracon, Veeradol, Victadol, Vintram, Xidol, Zamadol, Zytram

Similar Products:
Diflucan, Ambien, Levitra, Sovaldi, Sporanox

Also known as: Tramadol


{name} (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

{name} is used to treat moderate to severe pain in adults.

The extended-release form of tramadol ({name} ER) is for around-the-clock treatment of pain. {name} ER is not for use on an as-needed basis for pain.


Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Ultram: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Ultram is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Ultram dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Higher temperatures may cause the capsules to soften or melt. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Ultram are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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A reason for the reduced LC number may be an altered microenvironment in tumour tissue. To propose new frequency offset corrected inversion (FOCI) pulses with significantly reduced radiofrequency (RF) power deposition for spin echo imaging by incorporating the variable-rate selective excitation (VERSE) schemes into the pulse design. The temporal dynamics of the re-entry circuits, particularly the slowing of conduction as indicated by the crowding and zig-zag conducting of the activation isochrones, collocated well with scar substrate obtained by catheter voltage maps. Despite the well-established rewarding properties of these drugs, the reduction in intake of the taste cue has been interpreted as a conditioned taste aversion for decades. New insight into the synthesis of a novel azo-based optically active polyamidoamine side chain dendritic polyester architectural photoswitch. The cytotoxic activity of IL-2 stimulated PBL against K562, Jurkat and KYM-1 was evaluated. The histological findings as well as the usual differential diagnosis are discussed. Histamine binds to H1 sites on endothelial cells and induces changes in their shape that allow macromolecules to pass between them into the extravascular compartment. The role of protein phosphatase 2A catalytic subunit Calpha in embryogenesis: evidence from sequence analysis and localization studies.

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The total costs in the 6 months after first consultation for shoulder pain in primary care, mostly generated by a small part of the population, are not alarmingly high. We report two siblings from non consanguineous parents with a similar MCA/MR syndrome: Pre- and postnatal growth retardation, microcephaly, mental retardation, iris colobomata, facial dysmorphism, spasticity, dilated ventricles and abnormal immunoglobulin levels. The leaching behaviors of the P added to soil surface and the effect on subsurface Pb bioaccessibility must be addressed for this remedial technology to be acceptable. Hexamethylenelauramide (hexahydro-1-lauroyl-1H-azepine) was selected as a broad spectrum penetration enhancer worthy of further study. The short version of the Borderline Symptom List (BSL-23): development and initial data on psychometric properties. To avoid the influence of repeated food intake which stimulates renin release, the subjects were on continuous enteral nutrition. In a few cases, shortly after the onset of brain death, wave I and a wave II ipsilateral have been detected. Small-particle collection efficiency of vertical cylinders in flows of low-intensity turbulence. These are reassuring results given that a standardized approach to diagnosis was recommended and stimulant treatment is not first-line therapy for this age group.

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The Roles of Multidisciplinary Team Members in the Care of Pregnant Women. Anti-idiotype to monoclonal anti-swine SLA antibody detects a common idiotype shared by mouse anti-SLA sera and elicits an anti-SLA activity. Mammalian cell shape is critically important to cell differentiation, apoptosis, cell division, and growth arrest. In aortic ring preparations precontracted with phenylephrine, EOCA induced a concentration-dependent relaxation that was significantly reduced by vascular endothelium removal and pretreatment with atropine, indomethacin, or glibenclamide but remained unaffected by pretreatment with L-NAME or TEA. We report the results of a prospective randomized controlled trial comparing point-of-care testing (POCT) with central laboratory testing (CLT) in a six-bed coronary care unit in a district general hospital.

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The instrument is calibrated by reconciling measured angles with vacuum magnetic reconstructions through a range of pitch angles. To test this hypothesis, 122 patients from two dialysis centers were studied. Population-based data show that one in six newly diagnosed cancer patients received care from multiple institutions, and differed from patients seen only at a single institution. The clinical presentation, risk of systemic disease, pathogenesis, prognosis, and treatment options differ, largely depending on age at presentation. In this study, we investigated the association between the expression of MV antigens and MxA in subacute sclerosing panencephalitis (SSPE) brains.

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The mesentery of spontaneously hypertensive rats (SHRs) and their normotensive controls, Wistar Kyoto (WKY) rats, was examined with digital fluorescence microscopy after topical stimulation with an inflammatory mediator (f-met-leu-phe, 10(-8)M). Fifty percent of the operations are futile due to the presence of a locally advanced tumor or distant metastases. Gel mobility shift assays indicated that TraA is bound to a traA-ipd intergenic region, which is essential for cPD1 response. A catalytic manganese (Mn) cluster is required for the oxidation of water in the oxygen-evolving complex (OEC) of photosystem II (PSII) in plants. In this complex scenario, the role of genetic background likely represents a fundamental variable to attain successful aging and longevity. The theoretical calculations show that the dianions have aromatic oligothiophene moieties with two anionic dicyanomethylene groups. We identified a co-expression network of 320 genes (M30), which is significantly enriched for non-synonymous de novo mutations ascertained from patients with monogenic epilepsy and for common variants associated with polygenic epilepsy.

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Critical role of reactive oxygen species and mitochondrial membrane potential in Korean mistletoe lectin-induced apoptosis in human hepatocarcinoma cells. These studies were performed initially using thyrotropic tumor which lacked confounding gonadotropes. Furthermore, we show that pharmacophores derived from clusters of compounds resulting out of virtual screening could be useful probes for future structure-activity relationship studies (SARs) and fine-tune the lead molecules identified. Starting granulocyte-colony-stimulating factor (filgrastim) early after autologous peripheral blood progenitor cell transplantation leads to faster engraftment without increased resource utilization. The aim of our study was to describe the expression of c-erbB-1, c-erbB-2, c-erbB-3 and c-erbB-4 in endometrial cancer tissue and its correlation with clinicopathologic features and prognosis of the patients. Methodological approaches to the study of parenteral and tube feeding in an experiment. An efficient, sensitive, and rapid analysis of amino acids from in vivo perfusates of the vitreous is presented with 3-(4-carboxybenzoyl)-2-quinoline-carboxaldehyde (CBQCA) derivatitation and capillary electrophoresis (CE) separation with laser-induced fluorescence detection (LIF). The most significant qualitative difference in polycyclic aromatic hydrocarbon metabolism between the two species was the ability of the rat, but not the human, mammary epithelial cells to conjugate significant amounts of either polycyclic aromatic hydrocarbon to glucuronic acid. Primary analyses included elective, adult, inpatient surgical procedures from January 2013 to September 2015 available through University HealthSystem Consortium.


Primary neurological presentation is rare and we report a case that presented with obstructive hydrocephalus and infiltrative lesions in the brain unaccompanied by other features of accelerated phase. A detector based on spectral entropy surpassed two commonly used detectors based on peak-energy detection. It is proposed that the sex allocation theory, as applied to inbreeding populations, can explain the sex ratios observed for this diverse group of parasites. Membrane-based sample preparation coupled on-line to chromatography or electrophoresis. Specific host cytochrome B gene sequences were amplified by PCR and classified on the basis of their mobility in a heteroduplex assay. Hepatitis C virus infection propagates through interactions between Syndecan-1 and CD81 and impacts the hepatocyte glycocalyx. This report shows that TAE is a safe and effective therapy for patients with ADPKD with massively enlarged kidneys. Both the rigid and flexible bronchoscopes are used to diagnose and treat various pulmonary disorders.

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LCK, LAT, and the TCR all colocalized with lipid patches, although TCR association was sensitive to nonionic detergent. CFAR detection using waveguide invariant reverberation estimates is shown to outperform conventional cell-averaged and frequency-invariant CFAR detection methods in shallow water environments producing strong reverberation returns which exhibit the described striations. It is demonstrated that the system is capable of simultaneously acquiring B-mode, color Doppler mode and power Doppler mode small animal images. The resultant peptidic residues, which can be separated by thin-layer electrophoresis-thin-layer chromatography (2D TLE-TLC), SDS-PAGE, or HPLC, can be used in comparative studies or they can be recovered for further structural and immunological analyses. Among the various viral and non-viral gene delivery tools available, only adenoviral vectors have been tested for delivering SP-B cDNA to the lungs of animal models.

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Along with other recent studies, these findings suggest that improved care of depression in primary care is a prudent investment of health care resources. This newly cloned SLPI reduced HIV-1(Ba-L) infection in differentiated THP-1 cells, in contrast to the results observed when using commercially available preparations of SLPI. Syndrome of psychomotor retardation, bulbous nose norvasc type of medication , and epilepsy (Hernandez syndrome): a Brazilian case. From a strategic point of view, one major emphasis of :envihab is to form a closely interrelated network of scientists and the industry and the public. Platelet response to aspirin was assessed with Multiplate ASPI-test before coronary angiography in 70 patients on previous aspirin treatment admitted for acute STEMI. The authors report on a case of middle cerebral artery occlusion that mimicked the appearance of an aneurysm on angiography in the setting of acute stroke. SHC-alpha5beta1 integrin interactions regulate breast cancer cell adhesion and motility. The therapeutic potential of recombinant hIGF-1 (rthIGF-1) stems from the fact that hIGF-1 resembles insulin in many aspects of physiology.

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A 62-year-old female patient presents to the emergency department with complaints of a bleeding vaginal mass, pain referred to the vaginal introitus and dysu-ria. After this initial loss, however, Intralipid was removed from the circulation after first-order kinetics. We found 12 genes that were more commonly mutated in transformed samples than in the preceding FL tumors, including TP53, B2M, CCND3, GNA13, S1PR2, and P2RY8. Study of antimalarial activity of chemical constituents from Diospyros quaesita. Membrane tether extraction from human umbilical vein endothelial cells and its implication in leukocyte rolling. However, a high dose may be required to achieve optimal growth, platelet count, and hemoglobin level. Prescriptive authority offers broad opportunities for advanced practice psychiatric nurses. Next, clinical usefulness was evaluated by correlating the values obtained by kinematic measurement with the clinical grade. The half disappearance time of SQA-NPFF was 2-fold greater than that of NPFF.

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The 1980s and 1990s witnessed a substantial wave of organizational restructuring among hospitals and physicians, as health providers rethought their organizational roles given perceived market imperatives. The role of tumor necrosis factor inhibitors in patients with RA. Key words:Dental trauma, extrusive luxation, dento-alveolar fracture, esthetic restoration. BCL6 expression in hypermethylated samples was higher than that in low methylated samples. Available evidence supports the recommendation to consider allogeneic HCT for all acute myeloid leukemia patients in MRD CR1. Rapid, simple genotyping method by the variable numbers of tandem repeats (VNTR) for Mycobacterium tuberculosis isolates in Japan--analytical procedure of JATA (12)-VNTR. Opportunities in hospital security for improving performance and enhancing recognition through a highly professional public safety team exist in a number of areas. Molecular-based synthetic approach to new group IV materials for high-efficiency, low-cost solar cells and Si-based optoelectronics. The PTHrP levels in the conditioned medium also decreased in a similar dose-dependent manner.

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Hydroxycinnamoyl Glucose and Tartrate Esters and Their Role in the Formation of Ethylphenols in Wine. The Mre11 complex acts as a sensor of DNA double-strand breaks (DSBs) and regulates the signal transduction cascades that are triggered following damage detection.(1) Rare human genetic instability syndromes such as Ataxia-telangiectasia (A-T) and Nijmegen Breakage Syndrome (NBS) have underscored the importance of the DSB response in the suppression of tumorigenesis, as well as other severe pathologies affecting the development of both the immune system and the central nervous system. Intraarterial digital subtraction angiography was performed at 7 days, 2 weeks, and 1 month postprocedure. Three-dimensional relationship of the glenohumeral joint in the elevated position in shoulders with multidirectional instability. The reaction with glutathione appears to be enzymatic as 1-chloro-2,4-dinitrobenzene was a potent inhibitor of this reaction.

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Published clinical experiences for the use of rFVIIa in trauma patients are limited to small series and case reports. MMP-2 was significantly elevated before dialysis, perhaps indicative of progressive chronic renal sclerosis. Application of a widely electrically tunable diode laser to chemical gas sensing with quartz-enhanced photoacoustic spectroscopy. A study of its development against toxic doses of isoproterenol. The influence of vacuum assisted drainage on arterial line emboli. Pinnae measurements were obtained for 7 days following challenge to determine the magnitude of the inflammatory response. Knowledge of the clinical characteristics of these second other-site primary cancers becomes important especially during their follow-up surveillance.

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Identical satellite DNA sequences in how much do ventolin inhalers cost sibling species of Drosophila. DNA samples from 36 children with newly diagnosed precursor-B ALL were available for molecular analysis. Application of 5 ml seminal plasma into the tip of a ligated uterine horn lead to 3.6 h (mean) earlier ovulation on the adjacent ovary. Here we describe the isolation and culture of 47 nematodes with microsporidian infections. Our results imply that dendritic stratification of ferret ON and OFF RGCs, as in other mammals, occurs independently of visually driven activity. Spectrophotometric method of determination of the content of sodium salt of nalidixic acid (NA-Na). Survival curves by TNM stage and other prognostic factors are described.

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In a phylogenetic tree, the mouse and human DinB1 proteins specifically group with E. Using sequence and structural information, we predict that the GNAT homologous region contains the O-GlcNAcase activity. Arrangement of artificial teeth in the neutral zone after surgical reconstruction of the mandible: a clinical report. Moreover, MRI has the advantage of allowing simultaneous investigation of the biliary tree, owing to cholangiopancreatography techniques. Antithrombotic and antiallergic activities of daidzein, a metabolite of puerarin and daidzin produced by human intestinal microflora. Spread of bacteria of the genus Acinetobacter in the hydrobios of the Bay of Peter the Great, the Sea of Japan. In our environment, a substantial proportion of cases due to Staphylococcus microorganisms was observed. Polyethylene oxide (PEO)-hyaluronic acid (HA) nanofibers with kanamycin inhibits the growth of Listeria monocytogenes.

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