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Wellbutrin (Bupropion)
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Wellbutrin

Wellbutrin works in depression by increasing the levels of chemical messengers in the brain that helps in regulating mood. The mechanism underlying its use in smoking addiction are not fully understood.

Other names for this medication:
Aplenzin, Budeprion, Bupdep, Bupraset, Bupron, Bupropion, Ession, Nicotex, Smoquit, Unidep, Zyban

Similar Products:
Allegra, Ovral, Floxin, Naprosyn, Cycrin, Alprostadil, Silagra, Xanax, Mysoline

Also known as: Bupropion

Description

{name} (bupropion) is an antidepressant medication used to treat major depressive disorder and seasonal affective disorder.

Dosage

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Too much of this medicine can increase your risk of a seizure.

You may take Wellbutrin SR with or without food.

Swallow the extended-release tablet whole and do not crush, chew, or break it.

You should not change your dose or stop using Wellbutrin SR suddenly, unless you have a seizure while taking this medicine. Stopping suddenly can cause unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

If you take Zyban to help you stop smoking, you may continue to smoke for about 1 week after you start the medicine. Set a date to quit smoking during the first 2 weeks of treatment. Talk to your doctor if you have trouble quitting after taking Zyban for 7 to 12 weeks.

Your doctor may prescribe a nicotine replacement product (such as patches or gum) to help you stop smoking. Start using the nicotine replacement product on the same day you stop (quit) smoking or using tobacco products.

Some people taking Wellbutrin SR (Wellbutrin or Zyban) have had high blood pressure that is severe, especially when also using a nicotine replacement product (patch or gum). Your blood pressure may need to be checked before and during treatment with this medicine.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

You may have nicotine withdrawal symptoms when you stop smoking, including: increased appetite, weight gain, trouble sleeping, trouble concentrating, slower heart rate, having the urge to smoke, and feeling anxious, restless, depressed, angry, frustrated, or irritated. These symptoms may occur with or without using medication such as Zyban.

Smoking cessation may also cause new or worsening mental health problems, such as depression.

This medicine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use Wellbutrin SR.

Store at room temperature away from moisture, heat, and light.

Detailed Wellbutrin SR dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Wellbutrin XL can be fatal. Overdose symptoms may include muscle stiffness, hallucinations, fast or uneven heartbeat, shallow breathing, or fainting.

Storage

Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Wellbutrin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Drinking alcohol with bupropion may increase your risk of seizures. If you drink alcohol regularly, talk with your doctor before changing the amount you drink. Bupropion can also cause seizures in people who drink a lot of alcohol and then suddenly quit drinking when they start using the medication.

Bupropion may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

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Spontaneous rupture of the normal esophagus: report of a case with an unusual clinical course and pathologic findings. The hypervariable loops are all visible in the electron density map with the exception of three residues in the first hypervariable loop of the light chain. Large multicenter studies that include all children with perinatal stroke are needed to determine further the risk factors and outcome of perinatal stroke. On the other hand, AT2 receptor stimulation induced apoptosis myofibroblasts associated with reduced interstitial fibrosis. Botulinum neurotoxin is the most potent naturally occurring toxin known to inhibit various neurotransmitters. A redescription of Protospirura muricola Gedoelst, 1916 (Nematoda: Spiruridae), a parasite of murid rodents.

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Cost-effectiveness of inhaled nitric oxide in near-term and term infants with respiratory failure: eighteen- to 24-month follow-up for Canadian patients. Some rats were naive at the start of spatial training, whereas other rats received water maze strategies pretraining prior to spatial training to familiarize them with the general behavioral strategies required in the task. In addition, the greatly elevated content of thiobarbituric acid reactive substances (TBARS) and carbonylated protein in diabetic rats were reduced by P55A treatment. NHE) was measured for MP8, which was almost identical to that reported for N-acetyl-MP8 in aqueous solution. Pharmacological inactivation of the EGFR and ERK kinase activities, by use of specific inhibitors AG1478 and PD98059 respectively, blocked PV-IgG-induced phosphorylation of EGFR, ERK and c-Jun and cellular apoptosis, measured by flow cytometry and caspase 3 activity. Dual PPARalpha/gamma ligand TZD18 either alone or in combination with imatinib inhibits proliferation and induces apoptosis of human CML cell lines. Childbirth-related perineal trauma: clinical significance and prevention. In neurons of mutant animals, PI(4,5)P2 levels are increased, and clathrin-coated vesicles accumulate in the cytomatrix-rich area that surrounds the synaptic vesicle cluster in nerve endings. The clinical prediction rules are helpful for improved clinical decision making for bacteremia patients.

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Analysis of HtrA1 serine protease expression in human lung cancer. The radical SAM tryptophan (Trp) lyase NosL involved in nosiheptide biosynthesis catalyzes two parallel reactions, converting l-Trp to 3-methyl-2-indolic acid (MIA) and to dehydroglycine and 3-methylindole, respectively. About 49,000 miners are defined as exposed (underground or processing), while the internal control group (surface only) consists of 15,000 workers. In mice with VM, the activities of myocardial MMP-2 and MMP-9 at acute stage increased significantly, then myocardial collagen amount elevated in recovery stage. The youth/adolescent questionnaire has low validity and modest reliability among low-income African-American and Hispanic seventh- and eighth-grade youth. Autonomic activation was investigated in response to facial expressions of emotion in adolescents and adults with WS, compared to age-matched normal controls and to age-, IQ- and language-matched individuals with learning or intellectual disabilities (LID).

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The cytoplasmic domain of human FcgammaRIa alters the functional properties of the FcgammaRI.gamma-chain receptor complex. Simultaneous detection of co-segregating missense mutations of the Toll-like receptor 4. Nations face numerous challenges in providing high-quality end-of-life care for their citizens, and an aging population that has a prolonged trajectory of decline and substantial needs for care magnifies these challenges. Genetic architecture of resistance to aphids and mites in a willow hybrid system. Eight male beagle dogs with moderate periodontitis were enrolled in this split-mouth, double-blind randomized trial with ethical approval.

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In some cases, these structures imitate the region of protein binding to rRNA. Physicians take lead in the integration of medication and disease management. A significant change in attitudes was evident, with the students feeling more comfortable interacting with people with disabilities after the session than before. None of the tested sorbents reduced the mercury concentration to less than the existing 12 ng/l NPDES limit. Each collagen type isolated from the treated tissue preparations displayed properties consistent with those exhibited by its counterpart obtained from fresh tissue which was directly processed. We used our recently published and experimentally validated L3-S1 finite element model for the present study. However, the physical nature of this DFT estimate of electron correlation energy is not well understood and, in fact, most current DFT methods do not describe dispersion energy at all.

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A reversed graft may ensure that regenerating nerve fibers are not lost at branching points, however this may not translate into improved function. In agreement with these changes, analysis of a major substrate of cyclin-activated cdks, retinoblastoma protein (Rb), showed an increase in the level of phosphorylated forms within 1 hr of KCl withdrawal. Mice bearing a luciferase reporter gene for mPer2 were subjected to a 6-h advance of the light cycle and molecular rhythms in suprachiasmatic nuclei (SCN), thymus, spleen, lung and esophagus were measured periodically for 2 weeks following the shift. These findings in pediatric encephalitis are suggestive of influenza A infection and may guide investigation and early diagnosis. Developmental indicators, established by measuring the length of florets and panicles, indicate that the critical stage for sex determination occurs when floret and panicle lengths are 1-2 mm and 3 cm, respectively. Percutaneous endovascular techniques are used increasingly in the vascular armamentarium. The fate of free cholesterol released after endocytosis of low-density lipoproteins remains obscure. Control patients were patients with CF not B cepacia complex colonized during the study period.

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The Fluoropen is a device consisting of a light source fitted with color filters to create the required emission and visualization wavelengths. Structural insights into Cdc45 function: was there a nuclease at the heart of the ancestral replisome?. Subsequent to concentration of Fcepsilon receptor I, the mast cell receptor for IgE, and colocalized tyrosine phosphorylation activity, Lyn kinase and other proteins anchored to the inner leaflet of the plasma membrane redistribute selectively with the receptor clusters in a process that depends on actin polymerization. We report the use of costochondral autograft as an interposition material in revision of trapeziectomy in trapeziometacarpal osteoarthritis and to study its usefulness. Selective regulation of integrin--cytoskeleton interactions by the tyrosine kinase Src. The following two groups were assessed: (1) an early relapse (ER) group of patients who experienced recurrence during AED withdrawal and (2) a late relapse (LR) group of patients who experienced recurrence after completion of the AED discontinuation process. However, four cages inserted through posterior exposure during an interbody lumbar fusion procedure had to be removed because of migration into the spinal canal.

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The modeling revealed that the intermolecular contacts of chymosin in crystal have negligible influence on the energy stabilization of its self-inhibited conformation. Physical Activity Contributes to Several Sleep-Cardiometabolic Health Relationships. Two independent assessments of ego level were related to IQ and defense mechanism use in a sample of 89 young adults. The maximum tolerable dose (MTD) of CDDP suppressed early-stage c26 and c38 tumor growth when treatment was started after the tumor volume (TV) reached 0.2-0.5 cm3, but it showed reduced activity against the same tumors at an advanced growth stage when TV exceeded 2 cm3. The first formant was very stable in every child and showed only discrete deviations from the normal range. Absolute left ventricular volume changes after sublingual nitroglycerine and nifedipine intervention.

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The characteristics and performance of FLURBIPROFEN 8.75 mg SPRAY were compared with 12 other sprays. Use of macrolides as part of an initial therapeutic regimen appears to be associated with shorter LOS. Cyclin A correlates with carcinogenesis and metastasis, and p27(kip1) correlates with lymphatic invasion, in colorectal neoplasms. Hepatocelluar norethindrone 5 mg coupon carcinoma is one of the commonest cancers in Nigeria. Using such an allelic series and a novel thermotolerance assay for Drosophila embryos, we investigated the role of the 70 kD heat-shock protein, Hsp 70, in thermotolerance.

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In total 70 patients, 53 men and 17 women, who were recruited into the study, were indicated for primary laparoscopic resection for colorectal carcinoma, with laparoscopic intra-operative ulrasonographic examination of the liver (L-IOUS) being used during the initial part of the operation. Fatty acid biomarkers of symbionts and unusual inhibition of tetracosapolyenoic acid biosynthesis in corals (octocorallia). Nasal carriage of methicillin-resistant staphylococcus aureus in vascular surgery. Functionalized oxepines via fragmentation of highly strained epoxides. The aim of this article is to provide a systematic review of the literature concerned, and to present a case series with representative defects from various zones.

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We formulated a prognostic index according to SPF and tumor stage that has discriminatory capacity for biologic behavior in colorectal tumors. In a study of 39 subjects, blood pressure was measured using two indirect methods (two-stage and one-stage approaches). This review focuses on the aims, results, advantages, and possible disadvantages of preoperative chemotherapy and endocrine therapy. Usefulness of an inexpensive, Paracheck test in detecting asymptomatic infectious reservoir of plasmodium falciparum during dry season in an inaccessible terrain in central India. Caricatures of faces of famous people and photographs of non-famous faces yielded higher percent signal changes in the OFA and FFA compared to photographs of famous faces. We highlight and discuss the different topological patterns recovered by concatenated and coalescent species tree methods for these closely related lineages.

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